Buying a home in Buffalo, South Carolina does not have to be difficult - Homes.com makes home buying a breeze. With 3 homes for sale in Buffalo, South Carolina, you can search by price, bedrooms, neighborhood, and even by property type. Search Buffalo homes for sale, foreclosures, MLS listings, and more. Make an informed decision with Buffalo school data, neighborhood information, find Buffalo real estate agents, and research home values in Buffalo, SC. Homes.com has everything you need but the house keys.