The area was originally patented in 1824 and was allegedly named by a settler from Fresno, California. By 1914, the area had been developed with a working telephone line, a post office, a general store and a hardware store. At this point, the population was 32, and the area remained relatively small through the 40s, 50s and 60s, maintaining a population of approximately 100. It wasn't until the 80s and 90s that the population boomed as a result of the growing Houston area. Today, the region has a number of modern bedroom communities including six central neighborhoods, Teal Run North, New Point Estates, Winfield Lakes, Andover Farms, Cambridge Falls and Fort Bend Tollway. While the area has grown and modernized, it maintains an intimate small community atmosphere.

Located in Fort Bend County, Fresno, Texas is defined as a Census Designated Territory. Fresno is bordered by Houston, Missouri City, Arcola, Pearland and Rosharon. With a population of 19,069, the territory is largely inhabited by families. The area contains a number of suburban neighborhoods with detached single-family homes. There are a very limited number of alternative housing options.

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