Buying a home in Hartsville, South Carolina does not have to be difficult - Homes.com makes home buying a breeze. With 378 homes for sale in Hartsville, South Carolina, you can search by price, bedrooms, neighborhood, and even by property type. Search Hartsville homes for sale, foreclosures, MLS listings, and more. Make an informed decision with Hartsville school data, neighborhood information, find Hartsville real estate agents, and research home values in Hartsville, SC. Homes.com has everything you need but the house keys.