Buying a home in Kirksville, Missouri does not have to be difficult - Homes.com makes home buying a breeze. With 218 homes for sale in Kirksville, Missouri, you can search by price, bedrooms, neighborhood, and even by property type. Search Kirksville homes for sale, foreclosures, MLS listings, and more. Make an informed decision with Kirksville school data, neighborhood information, find Kirksville real estate agents, and research home values in Kirksville, MO. Homes.com has everything you need but the house keys.