Buying a home in Lake City, South Carolina does not have to be difficult - Homes.com makes home buying a breeze. With 32 homes for sale in Lake City, South Carolina, you can search by price, bedrooms, neighborhood, and even by property type. Search Lake City homes for sale, foreclosures, MLS listings, and more. Make an informed decision with Lake City school data, neighborhood information, find Lake City real estate agents, and research home values in Lake City, SC. Homes.com has everything you need but the house keys.