Buying a home in Manistique, Michigan does not have to be difficult - Homes.com makes home buying a breeze. With 271 homes for sale in Manistique, Michigan, you can search by price, bedrooms, neighborhood, and even by property type. Search Manistique homes for sale, foreclosures, MLS listings, and more. Make an informed decision with Manistique school data, neighborhood information, find Manistique real estate agents, and research home values in Manistique, MI. Homes.com has everything you need but the house keys.