Buying a home in Matlacha, Florida does not have to be difficult - Homes.com makes home buying a breeze. With 1932 homes for sale in Matlacha, Florida, you can search by price, bedrooms, neighborhood, and even by property type. Search Matlacha homes for sale, foreclosures, MLS listings, and more. Make an informed decision with Matlacha school data, neighborhood information, find Matlacha real estate agents, and research home values in Matlacha, FL. Homes.com has everything you need but the house keys.