Buying a home in Saint James, Missouri does not have to be difficult - Homes.com makes home buying a breeze. With 98 homes for sale in Saint James, Missouri, you can search by price, bedrooms, neighborhood, and even by property type. Search Saint James homes for sale, foreclosures, MLS listings, and more. Make an informed decision with Saint James school data, neighborhood information, find Saint James real estate agents, and research home values in Saint James, MO. Homes.com has everything you need but the house keys.