Buying a home in Salem, South Carolina does not have to be difficult - Homes.com makes home buying a breeze. With 514 homes for sale in Salem, South Carolina, you can search by price, bedrooms, neighborhood, and even by property type. Search Salem homes for sale, foreclosures, MLS listings, and more. Make an informed decision with Salem school data, neighborhood information, find Salem real estate agents, and research home values in Salem, SC. Homes.com has everything you need but the house keys.