Buying a home in Sanibel, Florida does not have to be difficult - Homes.com makes home buying a breeze. With 314 homes for sale in Sanibel, Florida, you can search by price, bedrooms, neighborhood, and even by property type. Search Sanibel homes for sale, foreclosures, MLS listings, and more. Make an informed decision with Sanibel school data, neighborhood information, find Sanibel real estate agents, and research home values in Sanibel, FL. Homes.com has everything you need but the house keys.