Newest Homes for Sale in De Soto, IL

This is the one you've been waiting for! This magnificent custom-built cabin offers the perfect blend of modern luxury, expansive living space and storage, and absolute privacy, ideal for those seeking a grand family home or a serene nature retreat. Situated on a private road and nearly 19 acres of some of the best fields and forest Southern Illinois has to offer, it borders the Burning Star

Katarena Moroz KELLER WILLIAMS PINNACLE

Welcome to this move-in-ready 3-bedroom, 2-bath home in a quiet subdivision! The current owners have done a remarkable job refreshing this home! A new roof was installed in 2025, new flooring, new paint! Featuring solid counters throughout, vaulted ceilings, and over an acre of yard for playing and entertaining. The kitchen/dining/living is open-concept, perfect for hosting the approaching

Angela Horn REALTY 618 LLC

What a fantastic starter home for your family! This 3 bedroom home is located in a great neighborhood conveniently located close to the Desoto Park. Step inside to this open floorplan with a great kitchen with lots of counterspace and appliances. Nice sized bedrooms and a huge dry basement for added space. Nice private backyard and priced just right at 124,900

Nikki Rishel Southern Illinois Realty Experts Carbondale

4 bedroom, 2 bath home on a corner lot

Jenell Brookhouse C21 House of Realty, INC.

The perfect property with woods, a stocked lake and a great place to build! This 27-acre piece is located on the outskirts of DeSoto! Grab your fishing pole and head to the boat ramp or enjoy the sunsets while the wildlife is at your back door.

Nikki Rishel Southern Illinois Realty Experts Carbondale

Move-in ready with rustic charm! All the work’s been done, just move in and enjoy! This completely remodeled 3-bedroom, 1.5-bath home in De Soto sits on a spacious corner lot with plenty of yard space. Inside, you’ll find a large living room and a cozy family room featuring a wood-burning stove set against a beautiful stone wall — perfect for chilly nights. The home blends warm, rustic touches

Nikki Rishel Southern Illinois Realty Experts Carbondale

Great remodeled starter home conveniently located in DeSoto, check out this two bed one bath home with a fenced in backyard. Comes with a home warranty for peace of mind.

Nikki Rishel Southern Illinois Realty Experts Carbondale

Check out this property in the heart of DeSoto IL! This house is ready to be called HOME with your personal touch! This home features 3 bedrooms and 1 bathroom, new carpet, and new appliances! Check out this convenient property today!

Randi Lindsay House 2 Home Realty Carterville

This impressive residence offers over 3,500 sq ft of refined living space with captivating lake/pond views. Blending elegance and comfort, the home features 4 bedrooms, 3 bathrooms, and 2 fireplaces. A chef-inspired kitchen with high-end appliances, center island, and abundant cabinetry opens to inviting living area with a stylish wet bar designed for entertaining. The master suite features a

Nikki Rishel Southern Illinois Realty Experts Carbondale

Great rental property to own. 2 other rentals at 216 S Pecan and 500 E Washington DeSoto could be bought at the same time. Rent for this property is $1,050. Lease runs to 3/31/26. Take a look today. See rent sheet and floor plan under documents on the MLS. Seller says deposit is the same as the rent.

Mark Krones C21 HOUSE OF REALTY, INC. C

Great rental property to own. 2 other rentals at 103 Kim St and 216 S Pecan St DeSoto could be bought at the same time. Rent for this property is $1,200. Lease runs to 4/30/26. Solid renters. Take a look today. See rent sheet and floor plan under documents in the MLS. Seller says deposit is the same amount as the rent.

Mark Krones C21 HOUSE OF REALTY, INC. C

Great rental property to own. 2 other rentals at 103 Kim St and 500 E Washington St DeSoto could be bought at the same time. Rent for this property is $1,100. Lease runs to 4/30/26. Solid renter. Take a look today. Rents for all 3 properties and floor plan for this property under documents on MLS.

Mark Krones C21 HOUSE OF REALTY, INC. C

This 3 bedroom, 2 bath home has a lot of updates, including a new laundry room. New electric panel installed in 2024. With a main living room, family room, and extra room that could be used as a fourth bedroom, office, playroom, or whatever your needs might be, space is not an issue with this home. Home has a deck that overlooks the large backyard. Schedule an appointment to see this home today

ERIN CAMFIELD Infinity Realty of Southern IL

Nine acres of prime forest land accessed from Rt. 51 north. There is approximately 1300+' frontage. This would make a convenient commercial location OR a secluded homestead.

Pam Schilling COMMERCIAL REALTY ASSOCIATES

Great location! These 2 parcels are conveniently situated with easy access to city amenities. The lots are being offered together and equal slightly under .5 acre. They are close to Walker’s Bluff Winery and Casino. Together these lots offer the added advantage of city water and sewer, ensuring hassle-free utility access for development. Nice opportunity for a possible investment.

Cindy Canning C21 HOUSE OF REALTY, INC. CD