9

De Soto, WI Homes for Sale with Acreage

Section Image
  • S6284 Wisconsin 35, de Soto, WI 54624
    S6284 Wisconsin 35, de Soto, WI 54624
    S6284 Wisconsin 35, de Soto, WI 54624
    /18

    $119,900

    • Land
    • 4.1 Acres
    • $29,244 per Acre

    S6284 Wisconsin 35, de Soto, WI 54624

    Mississippi River View 4 acre Lot with an established driveway and electric already on the property! This incredible small acreage is located just 20 min. south of La Crosse along Hwy 35, and near the Genoa National Fish Hatchery and close to several nearby boat landings. A cleared level bench area at the top of the driveway awaits your preferred use! Hike into the woods and you will discover

    Dean Tainter CENTURY 21 Affiliated

    S6284 Wisconsin 35, de Soto, WI 54624
  • S7437 Forest Ln, de Soto, WI 54624
    S7437 Forest Ln, de Soto, WI 54624
    S7437 Forest Ln, de Soto, WI 54624
    /16

    $375,000

    $10K PRICE DROP
    • 2 Beds
    • 1 Bath
    • 1,862 Sq Ft

    S7437 Forest Ln, de Soto, WI 54624

    Escape to your own private retreat on 13.7 wooded acres in Wisconsin's scenic Driftless Area! Tucked away on a quiet dead-end road, this raised ranch offers 2 BR, 1 BA, an attached 2-car garage and fiber-optic internet availability. Large storage closet on main floor would work great to add a half bath or laundry or both. Enjoy abundant wildlife and excellent hunting for whitetail deer and wild

    Karla Frank-Anderson Bi-State Realty & Appraisals

    S7437 Forest Ln, de Soto, WI 54624
  • 9642 Wisconsin 35, de Soto, WI 54624
    9642 Wisconsin 35, de Soto, WI 54624
    9642 Wisconsin 35, de Soto, WI 54624
    /31

    $699,900

    $50K PRICE DROP
    • 5 Beds
    • 4 Baths
    • 3,950 Sq Ft

    9642 Wisconsin 35, de Soto, WI 54624

    Enjoy breathtaking Mississippi River views from this versatile property ideally located just off the main road for easy access. Thoughtfully designed to function as either a single-family residence or multi-family setup, the home offers the unique ability to separate living spaces, complete with independent utilities for added convenience and flexibility. Inside, you'll find two spacious living

    LeNae Schwickerath Riverstone Real Estate Services LLC

    9642 Wisconsin 35, de Soto, WI 54624
  • S5943 Shady Ln, de Soto, WI 54624
    S5943 Shady Ln, de Soto, WI 54624
    S5943 Shady Ln, de Soto, WI 54624
    /41

    $175,000

    $24K PRICE DROP
    • 2 Beds
    • 1 Bath
    • 1,084 Sq Ft

    S5943 Shady Ln, de Soto, WI 54624

    Unique fully furnished property in Wisconsin's scenic Driftless Region! Situated on just under 1.5 acres, this property features a 2bdr 1bath mobile home with an addition, a charming cabin complete with a kitchenette and full bath, and a spacious 4 car garage offering plenty of room for vehicles, boats, ATVs, and outdoor equipment. Both the mobile home and cabin are being sold fully furnished,

    Kari Beeman Rush Creek Realty

    S5943 Shady Ln, de Soto, WI 54624
  • S6998 Missel Rd, de Soto, WI 54624
    S6998 Missel Rd, de Soto, WI 54624
    S6998 Missel Rd, de Soto, WI 54624
    /20

    $225,000

    • Land
    • 10 Acres
    • $22,500 per Acre

    S6998 Missel Rd, de Soto, WI 54624

    Rare opportunity to own 10 m/l secluded acres in Wisconsin’s beautiful Driftless Area! This versatile property offers privacy, beautiful countryside views, and an excellent setting for a future home, or getaway. With no restrictions and no HOA, you’ll have the flexibility to make this property your own. Power, a well, and holding tank are already in place, adding value. Two existing buildings

    Kari Beeman Rush Creek Realty

    S6998 Missel Rd, de Soto, WI 54624
  • S8068 Will Kumlin Rd, de Soto, WI 54624
    S8068 Will Kumlin Rd, de Soto, WI 54624
    S8068 Will Kumlin Rd, de Soto, WI 54624
    /14

    $150,000

    • Land
    • 14.2 Acres
    • $10,563 per Acre

    S8068 Will Kumlin Rd, de Soto, WI 54624

    Hiking, Hunting, Fishing! With an established building site & widened driveway, this 14.2-acre wooded property near DeSoto offers a a great get-away! Excellent hunting on this property, nearby fishing, and forage for a variety of mushrooms & berries. Just minutes from the boat landing on the Mississippi River, it's an ideal spot for outdoor enthusiasts. Enjoy easy access to nearby campgrounds,

    Michele Williams Century 21 Affiliated

    S8068 Will Kumlin Rd, de Soto, WI 54624
  • 4.1 +/- ACRES Wisconsin 35, de Soto, WI 54624
    4.1 +/- ACRES Wisconsin 35, de Soto, WI 54624
    4.1 +/- ACRES Wisconsin 35, de Soto, WI 54624
    /39

    $110,900

    $15K PRICE DROP
    • Land
    • 4.1 Acres
    • $27,049 per Acre

    4.1 +/- ACRES Wisconsin 35, de Soto, WI 54624

    Mississippi River View 4 acre Lot with an established driveway and electric already on the property! This incredible small acreage is located just 20 min. south of La Crosse along Hwy 35, and near the Genoa National Fish Hatchery and close to several nearby boat landings. A cleared level bench area at the top of the driveway awaits your preferred use! Hike into the woods and you will discover

    Dean Tainter Century 21 Affiliated

    4.1 +/- ACRES Wisconsin 35, de Soto, WI 54624
  • 11215 Midway Ct, de Soto, WI 54624
    11215 Midway Ct, de Soto, WI 54624
    11215 Midway Ct, de Soto, WI 54624
    /30

    $715,000

    • 3 Beds
    • 2.5 Baths
    • 2,454 Sq Ft

    11215 Midway Ct, de Soto, WI 54624

    A rare Mississippi River estate offering unmatched craftsmanship, privacy, and panoramic main-channel views. This executive 3-bed, 3-bath residence is finished with premium details throughout — zoned LP furnace, custom cabinetry, granite surfaces, and a hand-crafted hardwood staircase anchoring the home’s elegant design. Sun-filled, open living spaces frame the river like a living masterpiece.

    Jenn Swiggum Wisconsin Land and Homes LLC

    11215 Midway Ct, de Soto, WI 54624
  • 65741 Desoto Bluffs Dr, de Soto, WI 54624
    65741 Desoto Bluffs Dr, de Soto, WI 54624
    65741 Desoto Bluffs Dr, de Soto, WI 54624
    /46

    $549,000

    $36K PRICE DROP
    • 2 Beds
    • 2 Baths
    • 2,300 Sq Ft

    65741 Desoto Bluffs Dr, de Soto, WI 54624

    Welcome to your Driftless retreat overlooking the breathtaking Mississippi River. Beautifully maintained 2 bedroom, 2 bathroom home in charming De Soto offers the perfect blend of comfort, investment potential, and unforgettable scenery. Inside, find warm, updated finishes including new hardwood flooring, a wood-burning stove, along with gas fireplace for an inviting atmosphere year-round. Living

    Emma Justin Rush Creek Realty

    65741 Desoto Bluffs Dr, de Soto, WI 54624
Wisconsin Vernon County

Homes for Sale with Acreage in De Soto, WI

How to Buy a Home How to Finance a Home How to Sell a Home

Disclaimer: Certain information contained herein is derived from information provided by parties other than Homes.com. All information provided is deemed reliable, but is not guaranteed to be accurate and should be independently verified.

Homes.com Licensing Information

§ 442-H New York Standard Operating Procedures

New York Fair Housing Notice

TREC: Information about brokerage services, Consumer protection notice

California DRE #01937601

Contact Homes.com Brokerage

Copyright © 2026 CoStar Group