Defiance Homes for Sale

/62
$775,000
- 3 Beds
- 3.5 Baths
- 5,601 Sq Ft
3840 Rooster Ridge Ln, Defiance, MO 63341

LOCATION is perfection! Travel down a paved road and arrive at your custom ranch home, with double garages, a finished basement, stunning seller/builder details with over 5,000 total finished SF! I need way more space here to describe all of the features. Large kitchen with second dining / living area arranged around the Buck stove fireplace. Brazilian cherry flooring, double wall ovens, long

Hope Fick

(636) 556-4474

3840 Rooster Ridge Ln, Defiance, MO 63341
Explore Defiance
/19
$325,000
- Land
- 5.03 Acres
- $64,612 per Acre
3077 S Highway 94 (5 03+ - Acres), Defiance, MO 63341

5.03 acre homesite with exceptional Missouri River Valley views just outside the heart of Defiance. This scenic property offers a rare opportunity to build your home where the landscape opens to sweeping countryside views and beautiful sunrise exposure over the valley. The property features a PRIVATE Lane with direct access to Hwy 94, providing convenient access while maintaining a peaceful

Meyer Auctions Meyer & Company Real Estate and Auctions

3077 S Highway 94 (5 03+ - Acres), Defiance, MO 63341
/3
$199,900
- Land
- 3.45 Acres
- $57,942 per Acre
0 Defiance Rd Unit 22755774, Defiance, MO 63341

This expansive 3.45-acre lot is ideally situated in the heart of downtown Defiance, offering a rare combination of space and convenience. The property features a charming, rustic red barn that adds a touch of character and potential for various uses, from storage to creative projects. The ample size of the lot provides plenty of room for development, gardening, or outdoor activities. With its

MO Realty MO Realty

0 Defiance Rd Unit 22755774, Defiance, MO 63341
/4
$587,000
- Land
- 5.87 Acres
- $100,000 per Acre
4 Cooper's Ct, Defiance, MO 63341

Nestled in the heart of St. Charles County near Defiance and New Melle, MO, Callaway Lake Estates offers a rare opportunity to build your dream home surrounded by natural beauty while remaining close to modern conveniences. This private community is designed for those seeking space, recreation, and long-term value. The development features 108 homesites, with 35 already sold in the first 18

Toni Dillon Trophy Properties & Auction

4 Cooper's Ct, Defiance, MO 63341
/19
$1,225,000
- Land
- 32.32 Acres
- $37,902 per Acre
032 Callaway Ridge Dr, Boone Township, MO 63341

Experience the ultimate in privacy and natural beauty with this stunning waterfront property nestled on approximately 32 wooded acres fronting the Gorgeous 168 acre Callaway Valley Lake. Choose the perfect, private home site overlooking this peaceful lake. and enjoy endless days of hunting, fishing, boating, and peaceful views. Additional features include your own private boat dock plus a

Kelly Beanblossom-Schlake Blondin Group, Inc

032 Callaway Ridge Dr, Boone Township, MO 63341
/4
$279,900
- Land
- 5 Acres
- $55,980 per Acre
5011 Lily Ridge, Defiance, MO 63341

Sunset Estates in St. Charles County MO. Four Luxurious home sites, on 5 acre lots. Located in the heart of Defiance and wine country. Bring your own builder/plans and build your dream home on one of these premium secluded, all wooded lots. Homesites are located on a private street with cul-de-sac. Homeowners will enjoy the peace and quiet, along with privacy. County water and high-speed

Bill McNair II First American Real Estate Co.

5011 Lily Ridge, Defiance, MO 63341
/2
$485,000 Coming Soon
- Land
- 9.05 Acres
- $53,591 per Acre
2461 Highway F, Defiance, MO 63341

This mostly level 9.05 Acres of land includes a well with a solar-powered pump and five frost-free spigots on the southeast side—perfect for gardens, orchards, or hobby farming. A gravel driveway has already been added along the south side for convenient access. Only a small portion of the front is in the 100-year floodplain, while the majority of the property sits outside of it, giving you

Catherine Shaw-Connely Tom Shaw, REALTORS

2461 Highway F, Defiance, MO 63341
/4
$151,000
- Land
- 5.03 Acres
- $30,020 per Acre
180 Steeple Point Dr Lot #7 Dr, Defiance, MO 63341

Awesome lot available in a rural subdivision

Dan Lauderdale Lauderdale Realty

180 Steeple Point Dr Lot #7 Dr, Defiance, MO 63341
/30
$949,900
- 4 Beds
- 5 Baths
- 2,436 Sq Ft
4075 Highway D, Defiance, MO 63341

NOT IN A SUBDIVISION, NO INDENTURES OR RESTRICTIONS!!!! NEW ROOF.This is a must see!!! This beautifully updated, well maintained home with 3 beds, (3) full (2) 1/2 baths is on 10 flat acres. Primary bedroom has a bay window, separate shower/jacuzzi tub. Family room has a wood burning fireplace. Relax on the covered porch that overlooks a water feature and the lake. Kitchen has granite

John Shaw Tom Shaw, REALTORS

4075 Highway D, Defiance, MO 63341
/9
$151,000
- Land
- 5.05 Acres
- $29,901 per Acre
130 Steeple Point Dr Lot #12 Dr, Defiance, MO 63341

Great Building Lot. Schedule an appointment and view this property today.

Dan Lauderdale Lauderdale Realty

130 Steeple Point Dr Lot #12 Dr, Defiance, MO 63341
/2
$152,000
- Land
- 5.06 Acres
- $30,040 per Acre
120 Steeple Point Dr Lot #13 Dr, Defiance, MO 63341

Another Great Lot in the Steeple Point Subdivision. Schedule your appointment to view today.

Dan Lauderdale Lauderdale Realty

120 Steeple Point Dr Lot #13 Dr, Defiance, MO 63341
/43
$1,499,000
- 4 Beds
- 3.5 Baths
- 4,461 Sq Ft
115 Markham Trail Ln, Defiance, MO 63341

Looking for the perfect multi-generational home or private in-law suite with its own entrance? This custom-built Lombardo Ranch on 5.44 acres checks every box. Thoughtfully designed with high-end upgrades throughout, this home blends style, comfort, and function in every detail.On the main level, you’ll find a chef’s kitchen featuring white custom cabinetry, quartz countertops, a striking

Madison Lantz Berkshire Hathaway HomeServices Select Properties

115 Markham Trail Ln, Defiance, MO 63341
/15
$550,000
- Land
- 10 Acres
- $55,000 per Acre
55 Rustic Lodge Ln, Boone Township, MO 63341

Beautiful 10 acre wooded lot located in Defiance! The heart of wine country, minutes away from the katy trial, parks, wineries and brewery. This 10 acre lot can be subdivided up to 3 lots. Bring your own builder and build the home of your dreams. No HOA , no restrictions. There is a $300 road maintance fee yearly, if there is no road maintance done for the year the fee will be $150 for that year.

Robyn Ackerman Blondin Group, Inc

55 Rustic Lodge Ln, Boone Township, MO 63341
/26
$295,000
- Land
- 5 Acres
- $59,000 per Acre
Lot 1 Boone Ridge Trail, Boone Township, MO 63341

Sitting on a quiet cove with over 600 feet of water frontage, this gorgeous, wooded 5 acres is the perfect place to build the home of your dreams. The pristine 70-acre lake is stocked with muskies, bass, and crappie, so your fishing retreat will be just outside your door. The subdivision even offers a boat dock and picnic area. Nearby attractions include The Historic Daniel Boone Trail, the Katy

Stephen Kaiser Trophy Properties & Auction

Lot 1 Boone Ridge Trail, Boone Township, MO 63341
/2
$238,900
- Land
- 8.89 Acres
- $26,873 per Acre
110 Steeple Point Dr Lot # 14 Dr, Defiance, MO 63341

WOW, nearly 9 acres for under $250,000. Schedule an appointment and view this lot today.

Dan Lauderdale Lauderdale Realty

110 Steeple Point Dr Lot # 14 Dr, Defiance, MO 63341
/16
$325,000
- Land
- 5.03 Acres
- $64,612 per Acre
3077 S Missouri 94, Defiance, MO 63341

A truly rare opportunity to purchase 5 unrestricted acres with exceptional Missouri River Valley views. Ideally located within walking distance of the charming town of Defiance and the Katy Trail. Enjoy a 10-minute scenic drive to several county parks, the Weldon Spring Conservation Area, Missouri River access, and the Busch Shooting Range. Or unwind at one of the region’s many wineries, as this

Sherry Ruyle Meyer & Company Real Estate

3077 S Missouri 94, Defiance, MO 63341
/9
$165,000
- Land
- 5.03 Acres
- $32,803 per Acre
161 Steeple Point Dr, Boone Township, MO 63341

Discover the perfect blend of natural beauty and tranquility with this picturesque 5-acre parcel known as lot #5. Nestled among rolling hills, this stunning property offers breathtaking views, mature trees, and peaceful surroundings—ideal for your dream home or private retreat.Meandering walking trails wind through the landscape, inviting you to explore the rich scenery and enjoy leisurely

Dan Lauderdale Lauderdale Realty

161 Steeple Point Dr, Boone Township, MO 63341
/5
$279,900
- Land
- 5 Acres
- $55,980 per Acre
5001 Lily Ridge Ct, Defiance, MO 63341

Four Luxurious home sites, on 5 acre lots. Sunset Estates in St. Charles County MO. Located in the heart of Defiance and wine country. Bring your own builder/plans and build your dream home on one of these premium secluded, all wooded lots. Homesites are located on a private street with cul-de-sac. Homeowners will enjoy the peace and quiet, along with privacy. County water and high-speed

Bill McNair II First American Real Estate Co.

5001 Lily Ridge Ct, Defiance, MO 63341
/4
$154,000
- Land
- 5.13 Acres
- $30,019 per Acre
150 Steeple Point Dr Lot #10 Dr, Defiance, MO 63341

Gorgeous Lot in Steeple Point. Great views and quite living.

Dan Lauderdale Lauderdale Realty

150 Steeple Point Dr Lot #10 Dr, Defiance, MO 63341
/47
$649,900
- 4 Beds
- 2.5 Baths
- 2,556 Sq Ft
1330 Lake Hollow Dr, Defiance, MO 63341

Enjoy the serenity of your own private retreat, surrounded by trees and nature while still being just minutes from shopping, dining, and entertainment. Inside, the stunning kitchen is a true showpiece—featuring quartz countertops, cherry cabinetry, stainless steel appliances, a massive island, and a spacious walk-in pantry. The main level shines with new 5” wide wood-plank luxury vinyl flooring,

Suzanne Matyiko ReeceNichols Real Estate

1330 Lake Hollow Dr, Defiance, MO 63341
/5
$675,000 Open Sun 1PM - 3PM
- 4 Beds
- 3.5 Baths
- 3,831 Sq Ft
35 Greenview Dr, Defiance, MO 63341

Enjoy serene country living on 3+level, wooded acres in picturesque Defiance! This spacious 4-bedroom, 3.5-bath ranch offers an open floor plan with hardwood flooring throughout, fresh paint, and a new roof. The expansive kitchen features custom oak cabinetry, Corian countertops, center island with cooktop, double ovens, Sub-Zero refrigerator, built-in desk, and pantry—flowing seamlessly into a

Victoria Meder Platinum Realty of St. Louis

35 Greenview Dr, Defiance, MO 63341
/4
$350,000
- Land
- 5 Acres
- $70,000 per Acre
12 Still Waters Ct, Defiance, MO 63341

Nestled in the heart of St. Charles County near Defiance and New Melle, MO, Callaway Lake Estates offers a rare opportunity to build your dream home surrounded by natural beauty while remaining close to modern conveniences. This private community is designed for those seeking space, recreation, and long-term value. The development features 108 homesites, with 35 already sold in the first 18

Toni Dillon Trophy Properties & Auction

12 Still Waters Ct, Defiance, MO 63341
/67
$2,750,000
- 3 Beds
- 4.5 Baths
- 4,037 Sq Ft
353 Callaway Ridge Dr, Defiance, MO 63341

Experience the ultimate in privacy and natural beauty with this stunning custom waterfront property nestled on 37+ mostly wooded acres fronting the serene waters of Callaway Valley Lake. Crafted with exceptional attention to detail, this one-of-a-kind property showcases rich woodwork and impeccable craftsmanship throughout. Highlighted by a grand wood-paneled ceiling with softly arched beams, and

Kelly Beanblossom-Schlake Blondin Group, Inc

353 Callaway Ridge Dr, Defiance, MO 63341
/2
$99,900
- Land
- 3.08 Acres
- $32,435 per Acre
235 Quail Run Dr, Boone Township, MO 63341

3 acre wooded tract with million dollar views of peaks and valleys! Creek in the back attracts lots of wildlife year around. This is an established neighborhood of custom homes and this is one of the few lots available. Black top streets and public water.

Chad Matlick Coldwell Banker Realty - Gundaker

235 Quail Run Dr, Boone Township, MO 63341
/50
$950,000 Coming Soon
- 4 Beds
- 4.5 Baths
- 4,579 Sq Ft
50 Sunfish Dr, Defiance, MO 63341

Experience the best of Callaway Valley living—where privacy, luxury, and lifestyle align.Situated on a stunning 6-acre estate with coveted lake rights, this exceptional property offers a rare blend of space, serenity, and high-end living.The heart of the home is a chef’s dream kitchen, beautifully updated in 2022 with a 48” Wolf gas range with pot filler, Sub-Zero refrigerator, expansive

Jessica Settlemoir Realty Shop

50 Sunfish Dr, Defiance, MO 63341
/4
$350,000
- Land
- 5 Acres
- $70,000 per Acre
510 Callaway Estates Dr, Defiance, MO 63341

Nestled in the heart of St. Charles County near Defiance and New Melle, MO, Callaway Lake Estates offers a rare opportunity to build your dream home surrounded by natural beauty while remaining close to modern conveniences. This private community is designed for those seeking space, recreation, and long-term value. The development features 108 homesites, with 35 already sold in the first 18

Toni Dillon Trophy Properties & Auction

510 Callaway Estates Dr, Defiance, MO 63341
/98
$1,389,000 Open Sun 1PM - 3PM
- 5 Beds
- 5.5 Baths
- 5,504 Sq Ft
170 Blue Sky, Defiance, MO 63341

Brand new custom-built home on 3+ wooded acres in Kohler Estates subdivision. Features 4 bedrooms and 5 1/2 baths, a oversized 4 car garage with stair access to basement, a Great Room with a stone gas fireplace, with custom bookshelves, Gourmet kitchen offers custom cabinetry with quartz countertops, tile backsplash, and a complete appliance package, and walk-in pantry with custom shelving.

Chris Dawson Orenda Real Estate Services

170 Blue Sky, Defiance, MO 63341
/91
$785,000
- 4 Beds
- 3.5 Baths
- 4,564 Sq Ft
2 Woodridge Dr, Defiance, MO 63341

Spacious ranch home on 3 acres in one of the most beautiful settings in St. Charles County. Welcome home to picturesque rustic hardwood floors, a spacious country kitchen, large windows, vaulted ceilings, and TWO cozy fireplaces. The front, back, and side yards boast lovely mature trees placed perfectly to enhance the view and privacy. The pool (complete with a waterfall, salt water, and heater)

Kathleen Helbig EXP Realty, LLC

2 Woodridge Dr, Defiance, MO 63341
/2
$290,000
- Land
- 10.72 Acres
- $27,052 per Acre
190 Steeple Point Dr Lot #6 Dr, Defiance, MO 63341

Great home site in a rural setting.

Dan Lauderdale Lauderdale Realty

190 Steeple Point Dr Lot #6 Dr, Defiance, MO 63341
/3
$650,000
- Land
- 28.1 Acres
- $23,132 per Acre
Unlisted Address

Discover your private oasis on this rare 28.1-acre parcel in the sought-after Callaway Valley Subdivision! Perfect for your dream home or personal estate, this expansive property offers serene seclusion amidst lush nature, with the flexibility to create up to four (4) ideal building sites. Surrounded by custom homes on private roads and located within the highly regarded Francis Howell School

Suzanne Matyiko ReeceNichols Real Estate

Unlisted Address
/23
$300,000
- Land
- 5.01 Acres
- $59,907 per Acre
404 Stones Throw Ct, Defiance, MO 63341

Beautiful 5-acre building lot located in the highly sought-after gated community of Callaway Lake Estates! Bring your builder and design the home of your dreams while adhering to community building restrictions that help preserve the neighborhood’s character and value. Enjoy access to the 168-acre Callaway Lake, perfect for fishing, boating, and relaxing by the water. This prime lot is within the

Tim Phillips MO Realty

404 Stones Throw Ct, Defiance, MO 63341
/12
$155,000
- Land
- 5.17 Acres
- $29,981 per Acre
160 Steeple Point Dr Lot #9 Dr, Defiance, MO 63341

Dan Lauderdale Lauderdale Realty

160 Steeple Point Dr Lot #9 Dr, Defiance, MO 63341

Missouri St. Charles County Defiance Defiance

Why Live in Defiance

Defiance, an unincorporated community in southwest St. Charles County, Missouri, is characterized by its expansive lots and rural charm. Homes typically sit on lots of 5 acres or more, though 3-acre lots are also common. The area is part of the highly rated Francis Howell School District, with students attending Daniel Boone Elementary School, Francis Howell Middle School, and the newly relocated Francis Howell Union High School. Local attractions include the Defiance General Store on Highway 94, offering coffee, deli sandwiches, and ice cream, and Defiance Ridge Vineyards, known for its locally made wines. For outdoor enthusiasts, Matson Hill State Park provides 475 acres of forestland with 6 miles of trails for hiking and mountain biking, as well as the historic Hays Home. Despite its rural feel, Defiance is experiencing residential growth, with new construction spilling over from other parts of the county. The community maintains a low crime risk compared to the national average, making it a desirable location for those seeking privacy and a rural lifestyle.

Learn more about living in Defiance

Frequently Asked Questions

Is Defiance a good place to live?

Defiance is a good place to live. Defiance is considered very car-dependent and somewhat bikeable. Defiance is a rural neighborhood with a crime score of 2, making it safer than the average neighborhood in the U.S. Defiance has 7 parks for recreational activities. It is sparse in population with 0.1 people per acre and a median age of 51. The average household income is $153,599 which is above the national average. College graduates make up 48.6% of residents. A majority of residents in Defiance are home owners, with 5.3% of residents renting and 94.7% of residents owning their home. A local real estate agent serving Defiance can help you decide if this neighborhood is the right one for you. Learn more on our Defiance neighborhood guide.

Is Defiance, MO a safe neighborhood?

Defiance, MO is safer than the average neighborhood in the United States. It received a crime score of 2 out of 10.

How much do you need to make to afford a house in Defiance?

The median home price in Defiance is $749,000. If you put a 20% down payment of $149,800 and had a 30-year fixed mortgage with an interest rate of 6.37%, your estimated principal and interest payment would be $3,740 a month plus property taxes, HOA fees, home insurance, PMI, and utilities. Using the 28% rule, you would need to make at least $160K a year to afford the median home price in Defiance. Learn how much home you can afford with our Home Affordability Calculator. The average household income in Defiance is $154K.

What are the best public schools in Defiance?

The best public schools that serve Defiance are:

Francis Howell Middle School has an A Niche grade, a student teacher ratio of 16:1 and an average review score of 4.0.
Francis Howell High School has an A Niche grade, a student teacher ratio of 20:1 and an average review score of 4.0.
Daniel Boone Elementary School has an A Niche grade and a student teacher ratio of 14:1.

What are the most popular zip codes in Defiance, Defiance, MO?

The most popular zip codes in Defiance, Defiance, MO include 63341, 63385, 63332, 63073 and 63005.

Are home prices dropping in Defiance?

Yes, home prices in Defiance are down 6% in the last 12 months.

Home Trends in Defiance, MO

On average, homes in Defiance, MO sell after 54 days on the market compared to the national average of 55 days. The median sale price for homes in Defiance, MO over the last 12 months is $615,000, down 2% from the median home sale price over the previous 12 months.

Housing Trends

Median Sale Price

$615,000

Median Single Family Sale Price

$660,000

Average Price Per Sq Ft

$207

Number of Homes for Sale

Last 12 months Home Sales

Months of Supply

2.90

Median List Price

$749,000

Median Change From 1st List Price

Median Home Sale Price YoY Change

-2%

How to Buy a Home How to Finance a Home How to Sell a Home

Defiance Types of Homes for Sale

Defiance Land for Sale

More About Living in Defiance

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