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Buffalo, SC Homes for Sale

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  • 2428 Mount Lebanon Rd, Buffalo, SC 29321
    2428 Mount Lebanon Rd, Buffalo, SC 29321
    2428 Mount Lebanon Rd, Buffalo, SC 29321
    /31

    $220,000

    • 3 Beds
    • 1 Bath
    • 1,574 Sq Ft

    2428 Mount Lebanon Rd, Buffalo, SC 29321

    A Cottage in the Country with small town Charm, Community, and Conveinence! This charming gem of a home is perfect for either the first time home buyer or seasoned buyers. Located near growing Union, SC on a winding country road this amazing brick ranch home has been lovingly restored with a new roof, newer HVAC and Water Heater, updated to a modern gray and white color scheme, new luxury vinyl

    CHARLES JETER SPRINGS REALTY

    2428 Mount Lebanon Rd, Buffalo, SC 29321
  • 104 Drugstore St, Buffalo, SC 29321
    104 Drugstore St, Buffalo, SC 29321
    104 Drugstore St, Buffalo, SC 29321
    /31

    $121,500

    • 3 Beds
    • 1 Bath
    • 1,700 Sq Ft

    104 Drugstore St, Buffalo, SC 29321

    A great value with room to live and entertain! Check out this 3-bedroom, 1-bath on a corner lot in Buffalo. The home features large bedrooms and a spacious layout. A new furnace and water heater was installed in 2024 and new wall mounted heaters installed upstairs in Dec 2025. This property is located in a USDA eligible area!

    Jenna Fleming Keller Williams on Main

    104 Drugstore St, Buffalo, SC 29321
  • 258 Dupree Farm Rd, Buffalo, SC 29321
    258 Dupree Farm Rd, Buffalo, SC 29321
    258 Dupree Farm Rd, Buffalo, SC 29321
    /20

    $1,250,000

    • Land
    • 177.27 Acres
    • $7,051 per Acre

    258 Dupree Farm Rd, Buffalo, SC 29321

    Your ideal family compound awaits: 177 acres of serenity in Buffalo SC. This sprawling property is a rare gem, offering a blend of natural beauty, recreational opportunites and a sence of community that makes it perfect for families seeking a tranquil retreat. Bordered by Sugar Creek and Fairforest Creek, this land boasts scenic views and the soothing sounds of flowing water, enhancing the

    Kathy Morrow COLDWELL BANKER REALTY

    258 Dupree Farm Rd, Buffalo, SC 29321
South Carolina Union County Buffalo

Real Estate & Homes for Sale in Buffalo, SC

Frequently Asked Questions

What are the most popular zip codes in Buffalo, SC?
The most popular zip codes in Buffalo, SC include 29321, 29379, 29353, 29374 and 29335.
What are the most popular neighborhoods near Buffalo, SC?
The most popular neighborhoods near Buffalo, SC are Duncan Park, Forest Park, Hillbrook, South Converse and Converse Heights.
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