168

Florence County SC Homes for Sale with Acreage

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  • /10

    $130,000

    • Land
    • 4.00 Acres
    • $32,500 per Acre

    2492 Bridle Path Ln, Timmonsville, SC 29161

    Roughly +-4 acres to be subdivided out of a larger tract 00054-04-091. Property can be accessed from garner rd. or bridle path. Owner is willing to sell the half acre lot on garner rd separately from the 3.5 acres, or the entire tract as a whole. Has county water and will need septic permit if you desire to build a house on the property.

    Agent Photo

    Hunter Lowe

    Lowe Key Realty, Llc

    (843) 920-3585

    2492 Bridle Path Ln, Timmonsville, SC 29161
  • /13

    $59,700

    • Land
    • 1.70 Acres
    • $35,118 per Acre

    3141 Woodside Dr, Florence, SC 29541

    Discover the perfect opportunity to build your dream home on this spacious 1.7-acre residential lot located in the desirable Millwood Run subdivision. This lot offers a serene and picturesque setting, backing up to the tranquil Alligator Branch, providing a peaceful backdrop for your future residence.Contact your agent for more information or to schedule a viewing!

    Agent Photo

    Robricco Porter

    Coldwell Banker McMillan and Associates

    (843) 612-1932

    3141 Woodside Dr, Florence, SC 29541
  • /14

    $1,644,000

    • 10 Beds
    • 5 Baths
    • 14,576 Sq Ft

    200 Hudson Dr, Florence, SC 29506

    **Investment Opportunity -Charming Duplex Apartment Complex in Florence, SC**Discover an exceptional investment opportunity with this well-maintained apartment complex featuring 8 spacious duplexes, each designed for comfortable living. Located in the heart of Florence, SC, this property is an investor's dream, offering significant cash flow potential and strong returns.Each duplex consists of 2

    Agent Photo

    Tammy Lyles

    SM Realty & Associates LLC

    (843) 919-4679

    200 Hudson Dr, Florence, SC 29506
  • /28

    $375,000

    • Land
    • 27 Acres
    • $13,998 per Acre

    tbd Pandoras Path, Timmonsville, SC 29161

    26.79 acres in Florence County. With Florence County water, sewer, and dominion gas hookups on site. Roughly 5 acres of cleared land with paved road access, and a building pad already in place. The remaining 22+- acres have good timber value and provide privacy for your future homesite and mini farm. The current land owner is digging a shared pond that will be divided with the neighboring tract.

    Agent Photo

    Hunter Lowe

    Lowe Key Realty, Llc

    (843) 892-6578

    tbd Pandoras Path, Timmonsville, SC 29161
  • /2

    $399,900

    • Land
    • 1.38 Acres
    • $289,783 per Acre

    1521 2nd Loop Rd, Florence, SC 29505

    For sale a portion of lot located at 1521 2nd Loop Rd, approx 1.38 acres (lot is to the left side of the Carolina Trading Post. The actual address and TMS of the lot is TBD

    Agent Photo

    Chad Yates

    Assist 2 Sell, Buyers & Seller

    (843) 938-1717

    1521 2nd Loop Rd, Florence, SC 29505
  • /32

    $245,000

    • 3 Beds
    • 2 Baths
    • 1,650 Sq Ft

    226 S Wallace Rd, Florence, SC 29506

    What a fantastic property with tons of updates—and boy, does it look good! This 3-bedroom, 2-bath home sits on a beautiful one-acre lot and has been cared for with impressive improvements. In 2025, the entire home was freshly painted, including walls, trim & ceilings and a breakfast bar was added in the kitchen. In 2024, new septic field lines were installed, a moisture barrier was added and a

    Agent Photo

    Tom Snyder

    ERA Leatherman Realty, Inc.

    (843) 699-8488

    226 S Wallace Rd, Florence, SC 29506
  • /20

    $179,900

    • 3 Beds
    • 2 Baths
    • 1,960 Sq Ft

    4710 Jordan Cir, Timmonsville, SC 29161

    Very well kept home on a large 1.29 acre lot. Interior of the home features fresh paint, new heating and air system and new flooring. Great location just minutes from West Florence, private setting, brick underpinning.

    Agent Photo

    Chad Yates

    Assist 2 Sell, Buyers & Seller

    (854) 504-2753

    4710 Jordan Cir, Timmonsville, SC 29161
  • /4

    $35,000

    • Land
    • 1.18 Acres
    • $29,661 per Acre

    935 E Main St, Lake City, SC 29560

    OWNER FINANCING AVAILABLE- Discover the perfect opportunity to build your dream home or investment property on this 1.18-acre fully cleared lot located on E Main Street in Lake City, SC. With plenty of space and a level terrain, this property is ready for development, no need for clearing or heavy prep work.Situated in a convenient location just minutes from downtown Lake City, schools, shopping,

    Agent Photo

    Arturo Rojas Diaz

    SERHANT

    (843) 920-5543

    935 E Main St, Lake City, SC 29560
  • /14

    $559,900

    • 4 Beds
    • 3 Baths
    • 2,839 Sq Ft

    3703 State Road S-21-1389, Florence, SC 29501

    Discover refined luxury in this Modern farmhouse design, this home is to-be-built currently in the foundation phase. This plan features 2839sqft with 4 bedrooms, 3 bathrooms and a 2 car garage. This well appointed home will be situated on a 1.11 acre corner lot in Colonial Heights Subdivision in West Florence. There are many features and upgrades planned for the interior of this home from

    Agent Photo

    Chad Yates

    Assist 2 Sell, Buyers & Seller

    (843) 400-2112

    3703 State Road S-21-1389, Florence, SC 29501
  • /5

    $799,000 New Construction

    • 5 Beds
    • 3.5 Baths
    • 3,883 Sq Ft

    928 Barclay Dr, Florence, SC 29501

    Luxury New Construction on 1.06 Acres! Experience the perfect blend of elegance and space in this stunning new construction brick home nestled on over an acre. Boasting 5 large bedrooms, 3 full bathrooms, and a convenient half bath, this residence offers luxurious living at its finest. The gourmet eat-in kitchen features a spacious island, stainless steel appliances, and quartz countertops —

    Agent Photo

    Crystal White Stroud

    My Real Estate Group,LLC

    (854) 204-4521

    928 Barclay Dr, Florence, SC 29501
  • /40

    $650,000

    • 4 Beds
    • 2.5 Baths
    • 2,800 Sq Ft

    1128 Mclaughlin Rd, Effingham, SC 29541

    Welcome to 1128 McLaughlin Rd – a beautifully crafted, custom-built 4 bedroom, 2.5 bathroom home nestled on a 3 acres with no HOA, beautiful mature trees, and stunning views in every direction. Step into the grand foyer and you’re immediately greeted by a striking staircase with elegant iron railing leading to the second floor. The formal dining room boasts custom wainscoting and upgraded trim

    Laura Bryn Barnhill Coastal Land & Home

    1128 Mclaughlin Rd, Effingham, SC 29541
  • /19

    $124,900

    • 3 Beds
    • 2 Baths
    • 1,140 Sq Ft

    869 W Deer Rd, Timmonsville, SC 29161

    2016 Year Model Approximately 1140 Sq Ft Upscale Manufactured Home. 3 Bedrooms, 2 Ful Baths, Living Room, Eat in Kitchen with Range, Refrigerator and Dishwasher. Primary Bath with Garden Tub, Separate Shower and Dual Sinks Vanity. Central Heat and Air, Permanent Foundation, Public Water, Private Septic, 1.49 Acre Lot, Large Storage Building.fha, VA, usda, Conventional.

    Coye Sanders Carolinas Full Service Realty

    869 W Deer Rd, Timmonsville, SC 29161
  • /22

    $572,000

    • Land
    • 98 Acres
    • $5,847 per Acre

    Sugar Hill Fox Rd, Florence, SC 29505

    97+/- acre tract located in Pamplico, SC - Near Florence, SC! Being part of Sugar Hill Fox Pen, this property is partially fenced. Located at the front of the property is a small building that has water and power. Equipped with a mixture hardwoods and pines, this a great for the avid hunter. There is a small branch at the rear of the property that has the potential to make a great duck hunting

    Fred Chandler

    Sugar Hill Fox Rd, Florence, SC 29505
  • /81

    $450,000

    • 3 Beds
    • 2.5 Baths
    • 3,200 Sq Ft

    923 Moulds Rd, Lake City, SC 29560

    Welcome home to this turn-key equestrian farm with a beautiful custom house, large barn with living quarters and just under 15 acres of private land! Step into this well designed 3 bedroom, 2.5 bath home that offers easy single level living, perfect for the busy farm life! The spacious house includes 2 living rooms, a separate dining room, large eat-in kitchen, an office that could be used as a

    Jeanene Campbell Keller Williams Preferred

    923 Moulds Rd, Lake City, SC 29560
  • /41

    $1,180,000

    • Land
    • 215 Acres
    • $5,488 per Acre

    00 E Myrtle Beach Hwy, Johnsonville, SC 29555

    Located along the Great Pee Dee River and Kingsburg Bridge, the Kingsburg Pee Dee River Tract blends recreation, agriculture, and investment potential. With approximately 155 acres of uplands and 60 acres of wetlands, the property provides ideal habitat for whitetail deer and wild turkeys, making it perfect for a family farm, hunting club, or private recreational retreat.The property features

    Matthew Brownlee

    00 E Myrtle Beach Hwy, Johnsonville, SC 29555
  • /6

    $269,000

    • Land
    • 45 Acres
    • $5,978 per Acre

    0 W Myrtle Beach Hwy, Johnsonville, SC 29555

    Located just outside Johnsonville, SC, this 45-acre recreational tract offers a versatile blend of recreational, commercial, and development potential. With approximately 1,980 feet of frontage along Hwy 378 and additional frontage on Capitola Road, the property provides excellent visibility and access.A 5-acre pasture fronts the highway, offering an ideal location for a homesite, business,

    Jack Beasley

    0 W Myrtle Beach Hwy, Johnsonville, SC 29555
  • /31

    $59,000

    • Land
    • 5 Acres
    • $11,753 per Acre

    E Street Luke Church Rd Unit LotWP001, Johnsonville, SC 29555

    Have you been thinking about getting out of the city? This beautiful, spacious farm has a peaceful setting that can only be found in the country! Located near US Highway 378, you are only 30 minutes from the rapidly growing towns of Florence and Conway, SC. With approximately 3.5+/- acres of open farmland, you have plenty of options to build your dream estate, hunting property, or generate

    Jay Garner

    E Street Luke Church Rd Unit LotWP001, Johnsonville, SC 29555
  • /37

    $79,000

    • Land
    • 7 Acres
    • $11,254 per Acre

    E Street Luke Church Rd Unit LotWP002, Johnsonville, SC 29555

    Have you been thinking about getting out of the city? This beautiful, spacious farm has a peaceful setting that can only be found in the country! Located near US Highway 378, you are only 30 minutes from the rapidly growing towns of Florence and Conway, SC. With approximately 4+/- acres of open farmland, you have plenty of options to build your dream estate, hunting property, or generate income.

    Jay Garner

    E Street Luke Church Rd Unit LotWP002, Johnsonville, SC 29555
  • /46

    $119,000

    • Land
    • 12 Acres
    • $9,884 per Acre

    E Street Luke Church Rd Unit LotWP000, Johnsonville, SC 29555

    Have you been thinking about getting out of the city? This beautiful, spacious farm has a peaceful setting that can only be found in the country! Located near US Highway 378, you are only 30 minutes from the rapidly growing towns of Florence and Conway, SC. With approximately 8+/- acres of open farmland, you have plenty of options to build your dream estate, hunting property, or generate income.

    Jay Garner

    E Street Luke Church Rd Unit LotWP000, Johnsonville, SC 29555
  • /16

    $2,200,000

    • 3 Beds
    • 2 Baths
    • 1,300 Sq Ft

    1339 Johnsonville Hwy, Lake City, SC 29560

    The Sharp Farm is located just outside of Lake City, South Carolina, in Florence County. The sprawling 435-acre tract has it all, and it's the perfect property for someone seeking a comfortable weekend getaway in the country. Nearly 65 acres of the property are open fields, which are planted and farmed annually. A smaller 10-acre field is planted and used for fall dove hunts. Roughly 32 acres of

    Robert McCants

    1339 Johnsonville Hwy, Lake City, SC 29560
  • /3

    $118,000

    • Land
    • 45 Acres
    • $2,599 per Acre

    122 Beans Ln, Johnsonville, SC 29555

    Lake Swamp Farm is a great location for a homesite or recreation tract located 5 miles west of Johnsonville, SC and 15 miles east of Lake City, SC. With being a 40 minute drive to Florence or an hour ride to Myrtle Beach beaches this tract is an optimal location for a southern rural home. Tract has frontage off of Lake City Hwy (HWY 341) along with access off of Beans Lane. This property has 14

    Steve McMillan Southeastern Forestry, Inc.

    122 Beans Ln, Johnsonville, SC 29555
  • /7

    $320,000

    • Land
    • 32 Acres
    • $10,000 per Acre

    0 E Twin Church Rd, Timmonsville, SC 29161

    Grist Mill Northwest consists of +/- 32 stunning acres of land for sale in Timmonsville, SC.Situated just 15 minutes from Florence and 30 minutes from Manning,, this 32-acre property provides an ideal balance of rural tranquility and convenient access to nearby towns and amenities, making it a prime choice for those seeking both peace and practicality.Optimal AccessibilityWith nearly 4,000 feet

    Jared Walker Compass South Inc.

    0 E Twin Church Rd, Timmonsville, SC 29161
  • /9

    $3,900,000

    • 4 Beds
    • 4.5 Baths
    • 3,000 Sq Ft

    0 Mill Branch Rd, Pamplico, SC 29583

    LOCATION: River Place Farm is located on historic Mill Branch Road off Old River Road in Florence County, SC. It sits approximately 16 miles from Florence, and 6 miles from downtown Pamplico.DESCRIPTION: River Place Farm covers 380.98 acres of meticulously manicured land. It features upland pine, hardwood bottoms, and 3,689 feet of frontage on the Great Pee Dee River. The property

    Andrew Chaplin PALMETTO COMMERCIAL REAL ESTATE

    0 Mill Branch Rd, Pamplico, SC 29583
  • /63

    $398,000

    • 5 Beds
    • 3.5 Baths
    • 2,610 Sq Ft

    4013 U S 52, Coward, SC 29530

    Welcome to 4013 US Hwy 52 in Coward, SC — a well-maintained dual-property gem set on over an acre of spacious, rural land. Offering both space and versatility, this property is ideal for families seeking room to grow, multigenerational living, or potential rental income — all while being conveniently located just minutes from Florence, SC and within easy reach of Hwy 378 for quick trips to Myrtle

    Amber Poling LPT Realty, LLC.

    4013 U S 52, Coward, SC 29530
  • /60

    $425,000

    • 4 Beds
    • 4 Baths
    • 3,601 Sq Ft

    2019 Cale Yarborough Hwy, Timmonsville, SC 29161

    OPEN HOUSE 7/12 11:00 TO 1:00 Welcome Home to this one of a kind traditional brick home on 4 acres! If you are looking for space in the country but close to the interstate you are in luck. This home has a country feel and is situated right off I-95. Short day trip to Myrtle Beach and Charlotte, NC. Upon entering the foyer you are greeted with hardwood flooring, heavy crown molding and wanes

    Abigail Howard Real Broker, Llc

    2019 Cale Yarborough Hwy, Timmonsville, SC 29161
  • /46

    $464,999

    • 3 Beds
    • 2.5 Baths
    • 2,906 Sq Ft

    4625 Old Dr S, Timmonsville, SC 29161

    Welcome to your dream home in the prestigious Old South Plantation subdivision of Timmonsville, South Carolina, just minutes from West Florence and conveniently located near I-20 and I-95. This immaculate 2,906-square-foot residence, nestled on a sprawling 2.08-acre lot, offers timeless elegance and modern comfort. Meticulously maintained, the home boasts gleaming hardwood floors, stainless steel

    Samuel Fryer Drayton Realty Group

    4625 Old Dr S, Timmonsville, SC 29161
  • /56

    $449,900

    • 5 Beds
    • 4 Baths
    • 3,338 Sq Ft

    4531 E National Cemetery Rd, Florence, SC 29506

    Charming Country Brick Home on 4 Acres with Pond. This spacious 5-bedroom, 4-bath home offers the perfect blend of country charm and modern comfort. Set on 4 picturesque acres with a serene pond, the brick residence features a freshly painted interior, stainless steel bathrooms, and a main-level owner’s suite. Enjoy peaceful living with plenty of room to roam—ideal for those seeking privacy and

    Ashley Drayton Drayton Realty Group

    4531 E National Cemetery Rd, Florence, SC 29506
  • /72

    $619,900

    • 7 Beds
    • 4.5 Baths
    • 6,276 Sq Ft

    1602 Cherokee Rd, Florence, SC 29501

    This spacious property offers a 5-bedroom, 3.5-bathroom main house with 4,676 sqft of living space, situated on 1.63 acres. The home features two full kitchens, perfect for multi-functional use, including a large, updated kitchen with a 4'x6' island, granite countertops, and a metal backsplash. Hardwood floors throughout the downstairs, dental crown molding, and a cozy family room with a gas log

    Tom Langan exp Realty Greyfeather Group

    1602 Cherokee Rd, Florence, SC 29501
  • /57

    $594,000

    • 3 Beds
    • 2 Baths
    • 3,706 Sq Ft

    4835 Willow Creek Rd, Florence, SC 29505

    Welcome to a truly unique country estate where historic charm meets modern amenities. Set on three picturesque acres, this exceptional property features a beautifully preserved main house built in 1880, offering timeless character and warmth throughout. Thoughtful updates have been seamlessly integrated, creating a comfortable and inviting home that honors its heritage. In addition to the main

    Steven Ateyeh EXP Realty LLC

    4835 Willow Creek Rd, Florence, SC 29505
  • /39

    $535,000

    • 3 Beds
    • 2 Baths
    • 1,352 Sq Ft

    3101 Willow Creek Rd, Florence, SC 29505

    For all Equine Lovers this is it: 19 Acres with a 5,300 square foot 18 stall horse barn, wash rack, 2 tack rooms and office with a full bath. 2 acre stocked pond; 53 x 40 pole shed. Dog pin. This is truly a special property. Nice home on front of property. So, a place for your horses, dogs, fish, equipment and people. Home can be split off and sold separately from land or vice versa.

    Joe McMillan C/B McMillan and Assoc.

    3101 Willow Creek Rd, Florence, SC 29505
  • /30

    $449,900

    • 3 Beds
    • 1 Bath
    • 1,316 Sq Ft

    130 N Mustang Rd, Florence, SC 29506

    2 Brick Ranch Homes---1) Home 3/1 Super Nice inside & 1 - Brick Ranch Home 3/2 coming available soon 1 -14x60 Singlewide Mastercraft All OF THIS IS A GREAT INVESTMENT PROPERTY 1-Double Wide 24x44 Mansion M 1n Garage Apartment 1 bedroom 1 bath den & kitchen & Garage 1 Rented Mobile Home Lot 1Tiny House MH 12x34 AHOY

    Jane Singleton Coldwell Banker McMillan and Associates

    130 N Mustang Rd, Florence, SC 29506
  • /8

    $659,900 New Construction

    • 4 Beds
    • 3.5 Baths
    • 3,328 Sq Ft

    4540 Tightrope Dr, Florence, SC 29501

    Welcome to Plum's Place! This stunning new construction home by Bean Builders LLC, situated on 2.70 acres in a beautiful setting. With 3,328 square feet, this thoughtfully designed residence offers the perfect combination of style, comfort, and functionality. Step inside to find an open and inviting floor plan featuring 4 spacious bedrooms and 3.5 bathrooms. A dedicated home office makes working

    Natasha Byrd House of Real Estate

    4540 Tightrope Dr, Florence, SC 29501
  • /35

    $189,000

    • 4 Beds
    • 3 Baths
    • 1,600 Sq Ft

    1098 State Road S-21-225, Johnsonville, SC 29555

    4 bedroom 3 full bath double wide mobile home on 2.01 acres of land. Private with well water and septic. There are 2 covered porches on the mobile home. Large metal shed on side of the property for storage. If you are looking to get away from it all this may be the place for you.

    Doug Joy RE/MAX Executive

    1098 State Road S-21-225, Johnsonville, SC 29555
  • /33

    $970,000

    • Land
    • 160 Acres
    • $6,062 per Acre

    TBD E Friendfield Rd, Coward, SC 29530

    Welcome to Legacy Hollow! A premier 160-acre tract nestled just outside Coward, South Carolina on E. Friendfield Road—only 20 minutes from both Florence and Lake City. This exceptional property offers the perfect blend of recreation, investment, and natural beauty. Key Features • Water Features: 3-acre pond and 0.5-acre pond • Recreation: Private shooting range, extensive road system, and

    Zeb Freeman Weichert Realtors - Freedom

    TBD E Friendfield Rd, Coward, SC 29530
  • /3

    $42,500

    • Land
    • 1.67 Acres
    • $25,449 per Acre

    4059 Twin Church Rd, Timmonsville, SC 29161

    1.67 Acre lot on Twin Church Rd ready for your dream home! The lot is cleared and also has a water tap for city water that is already installed!! There is also a septic tank permit on file that will convey with the property.

    Brandon Stepp Stepp One Real Estate & Property Management

    4059 Twin Church Rd, Timmonsville, SC 29161
  • /9

    $187,500

    • Land
    • 11 Acres
    • $17,789 per Acre

    10.5 Acres Leigh Ln, Florence, SC 29505

    This 10.5-acre wooded tract is tucked away at the back of Tara Village in South Florence, offering both privacy and potential. The property has deeded access through Aunt Prissey Court and Leigh Lane, giving it convenient entry points. It is zoned rural residential in the county, but right next door the city limits bring water and sewer service to the surrounding homes—making this a property with

    Brian Rodgers Northgroup Real Estate Llc

    10.5 Acres Leigh Ln, Florence, SC 29505
  • /3

    $272,000

    • Land
    • 64 Acres
    • $4,250 per Acre

    64AC Vox Hwy, Lake City, SC 29560

    64 AC FARM OFFERING 18AC OF CROPLAND AND BALANCE IN WOODS WITH LAKE SWAMP CROSSING THE BACK 3RD OF PROPERTY . GOOD DEER, TURKEY & DOVE HUNTING!!!

    Billy Mitchell Tidewater Properties

    64AC Vox Hwy, Lake City, SC 29560
  • /45

    $3,500,000

    • 3 Beds
    • 4 Baths
    • 2,500 Sq Ft

    739 & 741 Jones Rd, Lake City, SC 29560

    Take a step back in time with this quintessential Southern estate, the Jones Plantation. Situated on 285.6 acres, this property was once the home to a plantation producing rice and other crops as well as raising cattle. The raised antebellum style main house consists of 1 bedroom and one bathroom, multiple fireplaces along with a kitchen on the top level. Below you will find an ideal

    Rebecca Teal Epps Miles Eaddy Realty Inc

    739 & 741 Jones Rd, Lake City, SC 29560
  • /28

    $572,000

    • Land
    • 98 Acres
    • $5,847 per Acre

    97.83 Acres-TBD Sugar Hill Fox Rd Unit Chisolm Trail, Pamplico, SC 29583

    97+/- acre tract located in Pamplico, SC - Near Florence, SC! Being part of Sugar Hill Fox Pen, this property is partially fenced. Located at the front of the property is a small building that has water and power. Equipped with a mixture hardwoods and pines, this a great for the avid hunter. There is a small branch at the rear of the property that has the potential to make a great duck hunting

    Fred 'Davis' Chandler Tidewater Properties

    97.83 Acres-TBD Sugar Hill Fox Rd Unit Chisolm Trail, Pamplico, SC 29583
  • /13

    $265,000

    • Land
    • 7 Acres
    • $40,520 per Acre

    6.54 Acres-TBD Alligator Rd, Florence, SC 29501

    6.54 acres located on Alligator Road in Florence, SC! Looking for the perfect spot to build a home or open a business? Then take a look at this! Currently, unzoned, this 6.54 acres offers tons of potential. Located 15 minutes from downtown Florence and 10 minutes from Florence mall, this piece of land offers exclusion but close proximity to all things! There is a small adjoining pond at the rear

    Robert McCants Tidewater Properties

    6.54 Acres-TBD Alligator Rd, Florence, SC 29501

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