Florence County SC Homes for Sale

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  $99,000

  • Land
  • 2 Acres
  • $49,500 per Acre

  0 S Pamplico Hwy Unit 25025051, Pamplico, SC 29583

  WHAT AN ENTRANCE!! **2 Full ACRES! -- Almost 500 Ft frontage on S. Pamplico HWY... Right at the Start of the center of town! - Just across the street from Pamplico Rescue and ambulance. -- A multitude of opportunities for business in a prime location with excellent visibility! -- Seller is motivated and looking for offers! - Hurry while this opportunity is still available! -- Electricity

  Shawn Smith Atlantic Edge Real Estate

  0 S Pamplico Hwy Unit 25025051, Pamplico, SC 29583
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  /2

  $290,000

  • Land
  • 28.81 Acres
  • $10,066 per Acre

  5894 E Old Marion Hwy - + -28 81 Ac, Florence, SC 29506

  Hank Edwards Aiken & Company

  5894 E Old Marion Hwy - + -28 81 Ac, Florence, SC 29506
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  $160,000

  • Land
  • 0.87 Acre
  • $183,908 per Acre

  517 S Church St, Florence, SC 29501

  Large Lot, Just under an acre situated in a high traffic area of Florence close to downtown. Fronts on both Church Street and Barringer Street. Adjacent to Florence County EMS Station. Close to McLeod Hospital (less than 1 mile) as well as MUSC Hospital and Florence Regional Airport (both less than a 3 mile drive)

  Melissa Hucks Greystone Properties, Llc

  517 S Church St, Florence, SC 29501
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  /2

  $24,800

  • Land
  • 0.26 Acre
  • $95,385 per Acre

  335 Byrnes Cir, Johnsonville, SC 29555

  Build Your Dream Home in the Heart of Johnsonville. Discover the perfect place to create your dream home on this beautiful, cleared lot, ideally located within the city limits of Johnsonville. Enjoy the convenience of public water and sewer with no HOA restrictions, giving you the freedom to design a home that truly fits your lifestyle. Nestled in a peaceful, well-established neighborhood, this

  Jill Lovell Diamond Shores Realty

  335 Byrnes Cir, Johnsonville, SC 29555
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  /21

  $317,648 New Construction

  • 4 Beds
  • 2.5 Baths
  • 2,340 Sq Ft

  2994 Royal Bluff Ln, Florence, SC 29505

  Come tour 2994 Royal Bluff Lane! One of our new homes at The Bluffs at Mill Creek, located in Florence, SC. The Galen's classic design offers an open concept main level with an expansive living area. The kitchen, featuring a working island with room for seating and an oversized pantry, flows into a casual eating area then into the spacious family room. An additional flex room on the first floor

  D.R. Horton Builder

  2994 Royal Bluff Ln, Florence, SC 29505
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  /2

  $279,000 New Construction

  • 3 Beds
  • 2 Baths
  • 1,600 Sq Ft

  2718 Ivywood Rd, Florence, SC 29501

  Welcome to this new construction home in a desired neighborhood with NO HOA! Located conveniently to all that West Florence has to offer. With a split floor plan the primary bedroom is separate from the two guest bedrooms. Enjoy LVP flooring throughout, Whirlpool kitchen appliances and granite countertops. The primary features a walk in closet and its own primary bathroom.**More photos to come

  Abigail Howard Real Broker, Llc

  2718 Ivywood Rd, Florence, SC 29501
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  $849,900

  • 4 Beds
  • 4.5 Baths
  • 4,000 Sq Ft

  3241 Lakeshore Dr, Florence, SC 29501

  Discover your perfect 4000 sq-ft, lakefront sanctuary in this stunning four-bedroom, four-bathroom home with an additional bonus of a private entranced suite with full bath. Multigenerational living is a breeze with the main bedroom in one wing of the house, three addition full sized bedrooms and two full baths in another wing, and the additional full-suite in the lower level. This impressive

  Beth Jones C/b Mcmillan And Assoc.

  3241 Lakeshore Dr, Florence, SC 29501
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  $319,500 New Construction

  • 3 Beds
  • 2 Baths
  • 1,730 Sq Ft

  7417 E National Cemetery Rd, Florence, SC 29506

  Majestic Comfort Meets Modern Design. Step into this beautifully crafted 3-bedroom home featuring a split floor plan designed for privacy and functionality. The Owner’s Suite earns its “Majestic” title with generous proportions, a spacious walk-in closet, dual vanities, and a luxurious 5-foot walk-in shower insert. Interior Highlights: No carpet—Luxury Vinyl Plank flooring flows throughout.

  Dorothy Corriero Era Leatherman Realty, Inc.

  7417 E National Cemetery Rd, Florence, SC 29506
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  $1,149,000

  • Land
  • 158.59 Acres
  • $7,245 per Acre

  1315 Hill-Harrell Rd, Effingham, SC 29541

  Imagine enjoying the seclusion of 158 acres and being just minutes from the Heart of Florence or having an Exclusive Venue for Special Events!! The possibilities are endless on this amazing property with approx. 20 cleared acres and pathways that lead to so much wildlife and a stocked pond with brim and bass on approx. 1 acre complete with a concrete dock. The metal warehouse is 50 x 120 with a

  Dottie O'Neal C/b Mcmillan And Assoc.

  1315 Hill-Harrell Rd, Effingham, SC 29541
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  $160,000

  • 3 Beds
  • 2 Baths
  • 1,549 Sq Ft

  900 S Morris St, Lake City, SC 29560

  Welcome to 900 S Morris Street! A charming home nestled in the heart of Lake City! This property blends classic character with modern touches, creating a comfortable and inviting space that’s move-in ready. The beautiful Vinyl Flooring adds a Modern bright look to this Home. Outside, you’ll love the large yard, great for entertaining, gardening, or simply relaxing and enjoying the outdoors. The

  Bryce Miles Keller Williams Palmetto Sumter

  900 S Morris St, Lake City, SC 29560
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  $164,900

  • 3 Beds
  • 1.5 Baths
  • 1,550 Sq Ft

  454 E Glendale Dr, Florence, SC 29506

  Located in the Glendale subdivision, this property features 3 bedrooms, 1.5 bathrooms, and a 2-car carport. The living room, hallway, and bedrooms include original oak hardwood floors. The spacious kitchen has ample cabinets and countertops. The breakfast bar provides additional counter space and seating. The dining room with a ceiling fan adjoins the kitchen, creating a cozy space for morning

  Melissa Floyd Real Estate Direct

  454 E Glendale Dr, Florence, SC 29506
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  /2

  $22,800

  • Land
  • 0.25 Acre
  • $91,200 per Acre

  421 N Railroad Ave, Johnsonville, SC 29555

  Build Your Dream Home in the Heart of Johnsonville! Discover the perfect place to create your dream home on this beautifully cleared quarter-acre lot, ideally located within the city limits of Johnsonville. Enjoy the convenience of public water and sewer with no HOA restrictions, giving you the freedom to design a home that truly fits your lifestyle. Nestled in a peaceful, well-established

  Victoria Martin Diamond Shores Realty

  421 N Railroad Ave, Johnsonville, SC 29555
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  $229,900

  • 3 Beds
  • 2.5 Baths
  • 4,249 Sq Ft

  609 E Main St, Lake City, SC 29560

  Brick home with 3 bedrooms and 2.5 baths. Features hardwood floors in the living area with fireplace, separate living and dining areas, bonus room, detached carport, and is situated on approximately 0.73 acres. Minutes from downtown Lake City. This property is eligible under the Freddie Mac First Look Initiative through 3-1-2026

  Mack Bryant Transcendent Real Estate Group

  609 E Main St, Lake City, SC 29560
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  $40,000

  • Land
  • 0.89 Acre
  • $44,944 per Acre

  7 W Lynhurst Rd, Pamplico, SC 29583

  Welcome to Tupelo Farm! If you have been looking to build your dream home, this could be the perfect opportunity to do so. This nearly one-acre residential lot offers the perfect blend of peaceful country living and everyday convenience. With plenty of room to stretch out, enjoy wide-open space, fresh air, and the freedom to create your dream home just the way you want it. Tucked away from the

  Jackson Stephens Greystone Properties, Llc

  7 W Lynhurst Rd, Pamplico, SC 29583
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  /3

  $153,000

  • Land
  • 15.35 Acres
  • $9,967 per Acre

  TBD Alice Meyers Dr, Olanta, SC 29114

  15.35 ac of cleared land inside the city limits of Olanta SC that is ready to be sub-divided into lots. Water & Sewer present at property.

  Billy Mitchell TIDEWATER PROPERTIES OF SC,LLC

  TBD Alice Meyers Dr, Olanta, SC 29114
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  $219,900

  • 3 Beds
  • 2.5 Baths
  • 2,359 Sq Ft

  215 Brantley St, Lake City, SC 29560

  Welcome Home to 215 Brantley Street in Lake City, South Carolina! This beautifully updated home offers 3 spacious bedrooms, 2.5 bathrooms, and a fully finished basement—perfect for extra living space, a home office, or entertainment. Conveniently located just minutes from popular shopping and dining, this property combines comfort and convenience. Enjoy a brand-new kitchen complete with modern

  Shelley Johnson Re/max Professionals

  215 Brantley St, Lake City, SC 29560
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  $214,900

  • 3 Beds
  • 1 Bath
  • 1,419 Sq Ft

  918 S Edisto Dr, Florence, SC 29501

  Easy on the eyes and full of character, this 3 bedroom, 1 bath home offers charm, comfort, and countless updates—all situated on a large corner lot in the heart of Florence! Step inside to a spacious, bright den featuring a cozy fireplace, perfect for relaxing or entertaining. The formal dining room provides a great space for gatherings, while the updated kitchen shines with butcher block

  Jackson Stephens Greystone Properties, Llc

  918 S Edisto Dr, Florence, SC 29501
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  /19

  $198,000

  • 3 Beds
  • 2.5 Baths
  • 2,304 Sq Ft

  2007 Cypress Rd, Florence, SC 29505

  3-bedroom, 2.5-bath home featuring a cozy fireplace and a welcoming covered porch. Situated on a spacious lot, this home offers plenty of room to relax, entertain, and enjoy outdoor living. A perfect blend of comfort and space.

  Karen Congilaro Carolina Pines Realty Office B

  2007 Cypress Rd, Florence, SC 29505
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  /6

  $396,396

  • Land
  • 0.91 Acre
  • $435,600 per Acre

  0 Presbyterian Rd Unit 126968, Florence, SC 29501

  .91 Acres located behind Dunkin Donuts off Hwy 52 & I-95 Interchange in Florence. This parcel has been cut from the larger parcel represented by the tax map number. Contact listing agent for more information or copy of survey. Priced at $10/sq. ft.

  David Grantham Griggs, Floyd, And Grantham In

  0 Presbyterian Rd Unit 126968, Florence, SC 29501
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  /2

  $15,000

  • Land
  • 0.15 Acre
  • $100,000 per Acre

  2224 N Church St, Scranton, SC 29591

  Cleared residential lot

  Heather Nero Vylla Home, Inc

  2224 N Church St, Scranton, SC 29591

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