Downtown Florence is experiencing a remarkable transformation, attracting new development, local entrepreneurs, and increased visitor traffic. With its central location and strong community support for growth, this lot is perfectly positioned for a flagship business, mixed-use project, or commercial venture that complements the city's exciting momentum. Opportunities like this don't last long -

Kenneth Godbold Drayton Realty Group

Great opportunity to build on this vacant residential lot conveniently located to downtown Florence, McLeod Hospital and the Florence airport. This lot has potential for single family home or a duplex to be built. No mobile or manufactured homes allowed in city limits.

Abigail Howard Real Broker, Llc

.17 Acres Commercial – City Location Great investment opportunity! .17 acres of commercial land in the city. Acquired through tax sale with tax deed; quiet title action may be needed. Buyer to verify all details, restrictions, and tax info.

Tilly Thompson E&a Realty

Rare Opportunity in Prestigious Queensferry! Welcome to one of the last remaining residential lots in the highly sought-after Queensferry subdivision—Florence’s premier address for luxury living. Spanning 1.33 acres, this spacious homesite offers the perfect setting to build your custom dream home, surrounded by stately residences and mature landscaping. Enjoy the privacy and exclusivity of this

Reeves Cannon Greystone Properties, LLC

Commercial Lot – 1.96 Acres | Excellent Location! Don’t miss this rare opportunity to own nearly 2 acres of commercially zoned land in a high-traffic, rapidly developing area. This 1.96-acre parcel offers endless potential that is located in a desirable and accessible location and it's ready for your vision.

Joi Perkins Re/max Professionals

Commercial Land Tract Available 1329 Turner Road 3.53 acres with paved road frontage on 3 sides. Estimated 630’ on Freedom Blvd. Highly attractive curve with very high visibility and easy access. Over 17,000 VPD Rapidly growing area.

Corey Craig Diamond Shores Realty

This residential building lot is a perfect opportunity to build a custom home tailored to your lifestyle. Located in the established Williams Heights neighborhood, you'll enjoy the convenience of nearby shopping, schools, and everyday amenities—all while having the freedom to design the home you've always envisioned. The owner will consider Owner Financing with an acceptable deposit.

Vonda Sellers Ford ERA Leatherman Realty, Inc.

Prime 59-Acre Parcel in Rapidly Growing Area – Unlimited Potential Don’t miss this rare opportunity to own 59 acres of unzoned land in one of the fastest-growing areas in the region. Perfectly positioned for future development, investment, or private use, this expansive property offers unmatched flexibility and endless possibilities. Located just minutes from key transportation routes,

Emily Fisher exp Realty Greyfeather Group

Awesome opportunity to own a piece of commercial property located on East Palmetto Street. Property currently has a shop in need of some TLC. Call/Text Tilly Thompson 843-229-9403 with any questions.

Tilly Thompson E&a Realty

High-Visibility Commercial Parcel – E. Palmetto Street & Dunton Drive, Florence, SC This exceptional ±12.65-acre commercial parcel offers 493 feet of frontage on E. Palmetto Street and 1,063 feet on Dunton Drive, positioned just off the corner of Hwy 327 and E. Palmetto Street. Located approximately 5 miles from I-95 Exit 170 (327)—the same exit as Buc-ee’s—this site enjoys consistently high

Dorothy Corriero ERA Leatherman Realty, Inc.

Prime Commercial Opportunity – Approx. 4.65 Acres on Freedom Blvd, Florence, SC. Located at the high-visibility corner of Freedom Blvd and Gilbert Drive, this tract offers unmatched potential in a rapidly expanding area of Florence. With 706 feet of frontage on Freedom Blvd with Commercial General zoning, the site is ideal for a wide range of development projects. Property Highlights:

Dorothy Corriero ERA Leatherman Realty, Inc.

260' road frontage on 2nd Loop Road with high visibility. Property is zoned Mixed-Use that permits schools, churches, preschools, libraries, community centers, child or adult day care, post office, police or fire station, indoor commercial amusement, indoor recreation/personal fitness, outdoor recreation, light automobile repairs, hotels, motels, commercial inns, business services, personal

Matt Scalise Scalise Realty Powered by KW

Seize the opportunity to establish your business at this exceptional +/- 0.50 acre commercial outparcel, ideally situated fronting Hoffmeyer Road in the dynamic West End District of Florence, SC. This highly visible location offers approximately +/- 150 feet of road frontage on Hoffmeyer Road and along a main entrance leading into West End District, making it a prime spot for attracting foot and

Hayden Harrington The Harrington Company, LLC

Seize the opportunity to establish your business at this exceptional +/- 1.50 acre commercial outparcel, ideally situated fronting Hoffmeyer Road in the dynamic West End District of Florence, SC. This corner site is one of the most prime locations in all of Florence. This highly visible location offers approximately +/- 245 feet of road frontage on Hoffmeyer Road and +/- 250 feet on W Darlington

Hayden Harrington The Harrington Company, LLC

Opportunity to purchase five lots zoned R-5A, located next to multifamily housing and an established single-family residential neighborhood. Conveniently situated near healthcare, grocery stores, and other amenities.

John Etheridge lll PLC Commercial

Absolutely beautiful lot in Parkland Subdivision. With nearly an acre(.96) to build on there are SO MANY OPTIONS. The lot is accessed through a private drive with THIS lot being the only one on it! Beautiful, mature landscaping with plenty of Oak trees to keep this lot even more private. There is also a pond on the property that is shared with adjacent property owner. This is a rare gem in

Brandon Stepp Stepp One Real Estate & Property Management

Unimproved commercial lot. Adjacent to Florence National Cemetery. Zoned R-5A. Could build multi-family housing, Triplex, duplex, or residential home. Located in central area in East Florence.

Ross McMillan Coldwell Banker McMillan and Associates

Unimproved vacant lot zoned for residential use. Centrally located.

Ross McMillan Coldwell Banker McMillan and Associates

Located adjacent to McLeod Medical Campus. Centrally located. Residential vacant lot. Public sewer & water, and Electric source.

Ross McMillan Coldwell Banker McMillan and Associates

Great location near Francis Marion University. Almost 300’ of road frontage with lots of visibility for your business. Rapidly growing area with endless possibilities for development. Nearby 1.08 lot is available for $275,000.

Ken Jackson PLC Commercial

High traffic/visibility location with dedicated access to Darlington Street. Seller may consider sub-dividing for the right user. This price is for a parcel 90024-02-007 and a portion of parcel 00123-01-021.

Ken Jackson PLC Commercial

Great location across from Post Office and adjacent to the Truist Bank Building. Lot of potential here for multiple uses. All utilities available.

Ken Jackson PLC Commercial

Embrace the potential of this remarkable commercial property, ideally situated on a bustling thoroughfare just moments away from the heart of Florence's vibrant downtown. Spanning an expansive 0.62 acres with approximately 110 feet of road frontage, this offering presents a rare chance to secure a coveted piece of real estate in a high-traffic location with immense business prospects.

Laith Kalbuneh Re/max Professionals

Amazing Opportunity! Don’t miss your chance to own this prime piece of property offering dual access from Pamplico Hwy and Barkley Ave. Excellent visibility and accessibility make it ideal for a variety of uses. Property is also available for lease. ?? Call today for details or with any questions!

Tilly Thompson E&a Realty

Large Lot, Just under an acre situated in a high traffic area of Florence close to downtown. Fronts on both Church Street and Barringer Street. Adjacent to Florence County EMS Station. Close to McLeod Hospital (less than 1 mile) as well as MUSC Hospital and Florence Regional Airport (both less than a 3 mile drive)

Melissa Hucks Greystone Properties, LLC

Corner Lot on Church and Cohen Streets // Close to downtown Florence, McLeod Hospital (less than 1 mile) as well as MUSC Hospital and Florence Regional Airport (both less than a 3 mile drive) // Two adjacent properties also for sale. Adjoining Property on the Corner of Barringer and Cohen Streets with Block building, the property next to that corner lot on Barringer Street has a Metal

Melissa Hucks Greystone Properties, LLC

Property backs up to Property fronting on Barringer also available for sale. Close to downtown Florence, McLeod Hospital (less than 1 mile) as well as MUSC Hospital and Florence Regional Airport (both less than a 3 mile drive) Multiple other properties available for sale in close proximity.

Melissa Hucks Greystone Properties, LLC

This property fronts on Barringer Street. Metal building on site. Heavy Traffic Location. Also available for sale - adjacent property on the corner of Barringer and Cohen Streets that has a block building on site and adjoining property on the Corner of Cohen and Church Streets. Close to downtown Florence, McLeod Hospital (less than 1 mile) as well as MUSC Hospital and Florence Regional

Melissa Hucks Greystone Properties, LLC

Heavy traffic daily Close to downtown Florence, McLeod Hospital (less than 1 mile) as well as MUSC Hospital and Florence Regional Airport (both less than a 3 mile drive)

Melissa Hucks Greystone Properties, LLC

Prime building lot just off N. Cashua Drive with access to Cashua Drive. A portion of parcel 00123-01-012 will be added for a total site size of 3.17 acres as shown on the survey. All utilities available.

Ken Jackson PLC Commercial

Unlock the potential of this high-traffic, prominent corner site with excellent exposure on a bustling 4-lane highway just minutes from Downtown Florence's retailers, dining, and the growing cultural hub. This site offers a rare opportunity for investors and developers seeking a prime location in Florence's emerging market. Flat, buildable site with utilities available.

Kenneth Godbold Drayton Realty Group

Great residential lot in Florence South Carolina.

Philip Greenberg Greenberg Real Estate, LLC

Great piece of land on Corner of Oakland Ave and E. Marion St. in Florence South Carolina.

Philip Greenberg Greenberg Real Estate, LLC

Property was acquired through a tax sale, and has a tax deed, a quiet title action might be required to clear title. Buyer and buyers agent to verify all important details and any restrictions. Tax information received through CRS Tax Data. Please verify.

Tilly Thompson E&a Realty

Property was acquired through a tax sale, and has a tax deed, a quiet title action might be required to clear title. Buyer and buyers agent to verify all important details and any restrictions. Tax information received through CRS Tax Data. Please verify.

Tilly Thompson E&a Realty

Great 0.40 acre residential building lot, lots 80 and 81 have been combined to make one (1) lot. Located next to the Church on W Dixie Street.

David Wimberly Coldwell Banker McMillan and Associates

What A Beautiful Setting!!! This large, fabulous 1.30 acre lot located on desirable Cherokee Road is convenient to everything Florence has to offer. The lot is zoned residential and the possibilities are endless.

Jean Leatherman ERA Leatherman Realty, Inc.