Lafayette County FL Homes for Sale

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  /53

  $884,900

  • 3 Beds
  • 3 Baths
  • 2,273 Sq Ft

  536 SE Lakeview Dr, Branford, FL 32008

  Upscale lakefront living in beautiful North Central Florida! This stunning 2,200+ sq ft home sits on 8.68 acres just minutes from Branford and the crystal-clear springs of the Suwannee River. Designed with style and comfort in mind, the home features bamboo flooring, vaulted ceilings, and an open, light-filled floor plan perfect for entertaining or relaxing. The spacious kitchen is a chef’s

  Michael DeGeorge POOLE REALTY INC.

  536 SE Lakeview Dr, Branford, FL 32008
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  /32

  $433,920

  • Land
  • 54.24 Acres
  • $8,000 per Acre

  423 NW Keystone Dr, Mayo, FL 32066

  This 54-acre, High and Dry, property in Lafayette County, Florida offers excellent frontage on three roads: County Road 251, Keystone Road, and Longitude Road. The diverse land includes 22 acres of hardwoods, 17 acres of pasture with scattered trees, and 15 acres of planted pines. There are producing pecan, pear, and orange trees on the property, offering a promising start for a mini farm or

  Ryan Walker Southern Land & Homes

  423 NW Keystone Dr, Mayo, FL 32066
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  /45

  $650,000

  • 5 Beds
  • 2 Baths
  • 2,400 Sq Ft

  365 NW County Road 292, Mayo, FL 32066

  Off Grid Ranch style (Cyprus Wood Exterior) super energy efficient custom home complete with concrete floors, concrete roof and concrete walls (providing extreme insulation). Home was built 10 ft below Earth’s surface with a 10 in pipe providing Geothermal heating and cooling. Home features include: Pella brand windows, steel roof with 3 inches of poured concrete covered with more sheet metal

  Suzanne Rossignol UNITED COUNTRY DICKS REALTY

  365 NW County Road 292, Mayo, FL 32066
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  /42

  $369,900

  • 3 Beds
  • 2 Baths
  • 1,700 Sq Ft

  1339 E Main St, Mayo, FL 32066

  Completely updated ranch-style home offering the perfect blend of modern comfort and timeless character. Updated flooring runs throughout, complemented by a beautifully refreshed kitchen featuring new cabinetry, updated appliances, and an eat-in island ideal for gathering. The oversized primary suite is a true retreat, complete with a stunningly updated primary bath showcasing his-and-her

  Chelsea Morgan Focus Real Estate Group, Inc.

  1339 E Main St, Mayo, FL 32066
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  /72

  $350,000

  • 5 Beds
  • 3 Baths
  • 2,552 Sq Ft

  112 NE Rowan Rd, Mayo, FL 32066

  Situated on 4.2 acres in Lafayette County, this two-story home offers five bedrooms, three bathrooms, and a functional layout designed for a variety of living needs. The property spans three road frontages—US Highway 27, NE Rowan Road, and NE Rosemary Way—and features established landscaping with large live oaks, original flowering plants, and irrigated garden areas.The first floor includes a

  Candice Land United Country Smith & Associates

  112 NE Rowan Rd, Mayo, FL 32066
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  /27

  $348,000

  • 3 Beds
  • 2 Baths
  • 1,536 Sq Ft

  1564 S Sr-349 (6 Ac), Branford, FL 32008

  Beautifully updated home offering 3 bedrooms, 2 bathrooms, plus a dedicated office or flex space, all set on a peaceful 6-acre property. The home underwent a complete remodel in 2025 featuring brand-new upgrades throughout, including a metal roof, energy-efficient windows, HVAC system, appliances, luxury vinyl plank flooring, custom cabinetry, granite countertops, a spacious eat-in island,

  Renee Tillman DANIEL CRAPPS AGENCY, INC

  1564 S Sr-349 (6 Ac), Branford, FL 32008
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  /27

  $359,000

  • 3 Beds
  • 2 Baths
  • 1,536 Sq Ft

  1564 State Road 349, Branford, FL 32008

  One or more photo(s) has been virtually staged. Beautifully updated brick home offering 3 bedrooms, 2 bathrooms, plus a dedicated office or flex space, all set on a peaceful 6-acre property. The home underwent a complete remodel in 2025 featuring brand-new upgrades throughout, including a metal roof, energy-efficient windows, HVAC system, appliances, luxury vinyl plank flooring, custom cabinetry,

  Daniel Crapps DANIEL CRAPPS AGENCY, INC.

  1564 State Road 349, Branford, FL 32008
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  /69

  $624,500

  • 4 Beds
  • 2 Baths
  • 1,638 Sq Ft

  176 NE Lilac Cir, Mayo, FL 32066

  Spanning 91 acres MOL, this remarkable North Florida property offers a rare blend of history, infrastructure, and endless opportunity. At its heart stands the original 1936 farmhouse, a timeless reminder of generations past with walls that could tell stories of early mornings, hard work, and family traditions rooted deep in the land. An additional home, ready for some TLC, could be restored to

  Chelsea Morgan Focus Real Estate Group, Inc.

  176 NE Lilac Cir, Mayo, FL 32066
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  /37

  $485,000

  • 3 Beds
  • 2 Baths
  • 1,982 Sq Ft

  270 NE Edward Perry Ln, Mayo, FL 32066

  Don’t miss out on this beautifully updated home situated on 5 peaceful acres! Enjoy the best of country living while still being just minutes from town. The kitchen features new stainless-steel appliances and stunning granite countertops, creating a modern and functional space for cooking and gathering. A bonus room has been thoughtfully updated and makes the perfect home office. Step outside and

  Kristie Land DANIEL CRAPPS AGENCY, INC

  270 NE Edward Perry Ln, Mayo, FL 32066
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  /47

  $389,000

  • 4 Beds
  • 2 Baths
  • 1,638 Sq Ft

  #44 Cr 354, Mayo, FL 32066

  Spanning 44 acres MOL, this exceptional North Florida property offers a rare blend of history, infrastructure, and opportunity. The old farmhouse, in need of some TLC, could be restored to habitable condition in no time. The property features mostly open, usable land, ideal for crops, cattle, horses, residential construction, or investors seeking subdivision potential. Agricultural infrastructure

  Chelsea Morgan Focus Real Estate Group, Inc.

  #44 Cr 354, Mayo, FL 32066
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  /53

  $609,999

  • 4 Beds
  • 2 Baths
  • 2,225 Sq Ft

  374 NE Magnolia Rd, Branford, FL 32008

  Beautiful Brick Home on 24.3 Acres – Peaceful Country Living with Exceptional Amenities. Discover the perfect blend of comfort and functionality with this well-maintained 4-bedroom, 2-bath brick home offering 2,225 square feet of living space. Featuring a durable metal roof and brand-new laminate flooring, brand new A/C, wood burning fireplace, this home is move-in ready and designed for both

  Mike McGinty Hatcher Realty Services, Inc. Branford

  374 NE Magnolia Rd, Branford, FL 32008
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  /2

  $20,000

  • Land
  • 25,264 Sq Ft
  • $34,483 per Acre

  0 SW San Pedro Ave, Mayo, FL 32066

  Location! Location! Location! Beautiful parcel of land in Mayo, FL waiting for you to build your dream home. Please verify all information. Measurements are estimates. All offers are welcomed.

  Elizabeth Ganesh KELLER WILLIAMS SUBURBAN TAMPA

  0 SW San Pedro Ave, Mayo, FL 32066
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  $1,499,998

  • Land
  • 93.87 Acres
  • $15,980 per Acre

  1083 NE Old Bridge Rd, Mayo, FL 32066

  Discover this extraordinary 93.87-acre recreational retreat nestled along the enchanting Suwannee River. Relax on the inviting porch of the brand-new tiny home, which comfortably accommodates up to eight guests and offers breathtaking views of the river. With its open layout and a fully equipped kitchen featuring gleaming stainless steel appliances, you'll feel right at home! For those needing

  Elizabeth Phillips DANIEL CRAPPS AGENCY, INC

  1083 NE Old Bridge Rd, Mayo, FL 32066
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  /27

  $4,500,000

  • Land
  • 118.77 Acres
  • $37,888 per Acre

  Unlisted Address

  118± Acres | Permitted Rock Mine | Lafayette County, FL 118± acre permitted, operational limerock mine located just off US 27, west of Mayo in Lafayette County. Property features shallow limerock deposits for efficient extraction, along with additional sand resources. This site offers substantial reserves to support years of continued production, with permits already in place—saving significant

  Joshua McDougal Tides & Timber Realty LLC

  Unlisted Address
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  /49

  $315,000

  • 3 Beds
  • 2 Baths
  • 1,784 Sq Ft

  344 NE Candy Ln, Mayo, FL 32066

  Step into a home that feels like a work of art where every detail has been thoughtfully refreshed and every space tells a story. Recently remodeled by a talented painter, this home truly serves as a blank canvas brought to life with style and intention. Inside, you’ll immediately notice the fresh paint, updated windows, and beautiful new flooring that flows through most of the home. The large

  Chelsea Morgan Focus Real Estate Group, Inc.

  344 NE Candy Ln, Mayo, FL 32066
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  $275,000

  • 2 Beds
  • 3 Baths
  • 1,560 Sq Ft

  103 NE Suwannee River Dr, Mayo, FL 32066

  Located along the scenic Suwannee River in Mayo, this 2-bedroom, 3-bath home is situated on 3 private acres with beautiful river views and exceptional privacy. The spacious kitchen opens to a combined living and dining area, creating an inviting layout ideal for both everyday living and entertaining. A large pantry and separate laundry room provide added convenience and storage.The former

  Sondra Hunt UNITED COUNTRY SMITH & ASSOCIATES - NEWBERRY

  103 NE Suwannee River Dr, Mayo, FL 32066
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  /22

  $95,000

  • Land
  • 1.98 Acres
  • $47,980 per Acre

  TBD NE Tansy Rd (2 Lots), Mayo, FL 32066

  Uncover this stunning 1.98-acre property for sale, just a stone's throw from the iconic Suwannee River! This tranquil and private oasis is brimming with wildlife and offers the perfect backdrop for your dream home—whether a custom-built residence, a mobile home, or a delightful recreational getaway. With two convenient boat ramps nearby, you can easily indulge in kayaking and boating adventures.

  Elizabeth Phillips DANIEL CRAPPS AGENCY, INC

  TBD NE Tansy Rd (2 Lots), Mayo, FL 32066
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  /4

  $19,950

  • Land
  • 1 Acre
  • $19,950 per Acre

  00 SW Doe Rd, Mayo, FL 32066

  Discover the perfect opportunity to create your own slice of country living on this beautiful 1-acre residential lot in Lafayette County. Zoned residential, this spacious parcel offers the freedom and flexibility buyers are looking for—whether you're dreaming of building a custom home, starting a mini farm, or simply enjoying more privacy and open space. With plenty of room for a garden,

  Melissa J. Martinez REAL BROKER LLC - OCALA

  00 SW Doe Rd, Mayo, FL 32066
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  /3

  $24,000

  • Land
  • 1 Acre
  • $24,000 per Acre

  00 SW Roosevelt Cir, Mayo, FL 32066

  Nestled at the end of a quiet cul-de-sac, this expansive 1-acre property offers the perfect blend of tranquility and opportunity. Whether you're dreaming of building your forever home or creating a private retreat, this picturesque lot provides the ideal canvas. Surrounded by lush greenery and enjoying minimal traffic, the location is perfect for families, nature enthusiasts, or anyone seeking a

  Melissa J. Martinez REAL BROKER LLC - OCALA

  00 SW Roosevelt Cir, Mayo, FL 32066
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  /18

  $85,000

  • Land
  • 8.11 Acres
  • $10,481 per Acre

  185 SE Dees Ct, Mayo, FL 32066

  PRICE IMPROVEMENT! Don't miss this incredible opportunity! This 8.11-acre property in Mayo, Florida, has just seen a price reduction. Tucked away at the end of a peaceful cul-de-sac, this private sanctuary offers the perfect blend of tranquility and convenience, with local amenities just a short drive away. The property comes with previously active electric, water, and septic systems, but buyers

  Kimberly Campbell Hatcher Realty Services, Inc. Steinhatchee

  185 SE Dees Ct, Mayo, FL 32066
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  /26

  $469,900

  • 3 Beds
  • 3.5 Baths
  • 2,108 Sq Ft

  301 NE Ka-Di Ln, Branford, FL 32008

  Escape the noise and reclaim your independence on this pristine five-acre homestead where comfort meets total self-sufficiency. Surrounded by the quiet beauty of the Branford countryside, this property is a sanctuary designed for those who want to live off the land without sacrificing modern convenience. Fully fenced and ready for horses, cattle, or a sprawling organic garden, the grounds offer a

  Lyle Kastrati ENGEL & VOLKERS GAINESVILLE

  301 NE Ka-Di Ln, Branford, FL 32008
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  /26

  $255,000

  • Land
  • 5.06 Acres
  • $50,395 per Acre

  TBD NE Tansy Rd Trestle Dr, Mayo, FL 32066

  Uncover this stunning 5-acre property for sale, just a stone's throw from the iconic Suwannee River! This tranquil and private oasis is brimming with wildlife and offers the perfect backdrop for your dream home—whether a custom-built residence, a mobile home, or a delightful recreational getaway. With two convenient boat ramps nearby, you can easily indulge in kayaking and boating adventures.

  Elizabeth Phillips DANIEL CRAPPS AGENCY, INC

  TBD NE Tansy Rd Trestle Dr, Mayo, FL 32066
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  /27

  $180,000

  • Land
  • 25.27 Acres
  • $7,123 per Acre

  1285 SE Koon Lake Rd, Mayo, FL 32066

  Tucked away in the heart of Lafayette County, this 25+ acre wooded retreat offers the perfect blend of privacy, nature, and opportunity. Scattered with mature oaks, towering cypress trees, and natural Florida brush, the property provides a peaceful setting with an area already cleared for your future homesite. Approximately 8+ acres are high and dry, giving you plenty of room to build without the

  Chelsea Morgan Focus Real Estate Group, Inc.

  1285 SE Koon Lake Rd, Mayo, FL 32066
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  /4

  $25,000

  • Land
  • 1.05 Acres
  • $23,810 per Acre

  0 Tbd Unit 376712, Mayo, FL 32066

  Vacant lot located just outside the city limits of Mayo in Lafayettee County

  0 Tbd Unit 376712, Mayo, FL 32066
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  /12

  $188,000

  • 4 Beds
  • 2 Baths
  • 1,568 Sq Ft

  3075 SE County Road 405, Mayo, FL 32066

  Stunning mobile home set in the country on 2.71 acres. This property is located on a paved road and a short drive to Branford or Mayo. The land has beautiful natural woods and granddaddy live oak trees on it. The home was completely remodeled in 2018. Come and see it for yourself!

  Jacob Garnier DANIEL CRAPPS AGENCY, INC

  3075 SE County Road 405, Mayo, FL 32066
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  /32

  $290,000

  • 6 Beds
  • 4 Baths
  • 1,936 Sq Ft

  800 SE Lynx Rd, Branford, FL 32008

  This property offers a peaceful country escape near the scenic Suwannee River! Nestled on five acres of lush land, this listing includes two mobile homes: Mobile Home #1 – Ideal for a primary residence or rental opportunity, with a spacious layout and room for updates. Mobile Home #2 – Great for a guest house, second rental, or multi-generational living. Surrounded by nature, with mature

  Emma Garcia United Country Smith & Assoc Bell

  800 SE Lynx Rd, Branford, FL 32008
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  /7

  $299,000

  • Land
  • 38.5 Acres
  • $7,766 per Acre

  0 N County Road 53 Unit 795290, Other Florida, FL 32066

  **Charming Country Haven – 38.5 Acres of Endless Possibilities in Day, FL** Welcome to your dream retreat nestled in the serene landscapes of Day, Florida! This remarkable property offers a sprawling 38.5 acres of lush green pastures and peaceful tranquility, making it the perfect canvas for your future home or investment opportunities. As you drive along the paved road leading to this stunning

  Nathan Allen Hatcher Realty Services, Inc. Cross City

  0 N County Road 53 Unit 795290, Other Florida, FL 32066
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  /37

  $135,000

  • 2 Beds
  • 1 Bath
  • 1,186 Sq Ft

  133 SW Monroe Ave, Mayo, FL 32066

  Experience the best of small-town Florida living in this beautifully refreshed 1905 historic cottage located in the heart of Mayo, Florida. This unique property perfectly balances its turn-of-the-century roots with the essential modern upgrades you’ve been looking for, offering all the soul of an "Old Florida" home. The exterior radiates curb appeal, featuring a classic hipped-roof silhouette,

  133 SW Monroe Ave, Mayo, FL 32066
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  /32

  $299,000

  • 3 Beds
  • 2 Baths
  • 1,740 Sq Ft

  755 NW County Road 260, Mayo, FL 32066

  3-bedroom, 2-bath mobile home on 5.19 acres in Mayo, FL. The home offers a functional layout with a primary bedroom and private bath, plus two additional bedrooms. The property provides ample space for animals, gardening, or future use. Located in a quiet rural area with easy access to town amenities. Suitable for full-time living or investment.

  Andrew Poole POOLE REALTY INC.

  755 NW County Road 260, Mayo, FL 32066
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  /6

  $42,000

  • Land

  TBD Lot 21 3-River Estat, Branford, FL 32008

  BOAT RAMP LESS THAN A MILE AWAY, AS PICUTRED. VERY NICE LOCATION IN A RIVER COMMUNITY.

  Marisol Brown TRINITY ROSE REALTY, INC

  TBD Lot 21 3-River Estat, Branford, FL 32008
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  /23

  $145,000

  • Land
  • 20 Acres
  • $7,250 per Acre

  TBD C R 340, Mayo, FL 32066

  A true Lafayette County gem — diverse timberland with the kind of mixed upland and lowland terrain that serious hunters and outdoor enthusiasts dream about. Corner road frontage provides excellent access from two directions while the property itself transitions from high dry uplands into lush lowland timber, creating the exact edge habitat that concentrates deer, turkey, hog, and a wide variety

  Tucker Smith United Country Smith & Associates

  TBD C R 340, Mayo, FL 32066
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  /47

  $149,900

  • 2 Beds
  • 2 Baths
  • 651 Sq Ft

  786 SE Turkey, Mayo, FL 32066

  Registered RV campground with a move-in-ready 2BR/2BA home-ideal base for Steinhatchee fishing & scalloping or seasonal hunting. Set on quiet country acreage just south of Mayo and less than 3/4 of a mile off State Road 51, the cabin/home offers an open living area, full kitchen, two bedrooms, two baths, and practical storage. Two detached garages/workshops provide covered parking and gear space,

  Robert Mastrangelo Realty Hub

  786 SE Turkey, Mayo, FL 32066
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  /29

  $199,900

  • 3 Beds
  • 2 Baths
  • 1,248 Sq Ft

  591 SW San Pedro Ave, Mayo, FL 32066

  This beautiful 2023 doublewide offers the perfect blend of comfort and convenience in the heart of Mayo. Featuring 3 bedrooms and 2 bathrooms, this home is set on a high and dry half-acre lot with plenty of space to enjoy. Relax and cool off in the above-ground pool, or take advantage of the ramped entryway for ease of access. Located in a peaceful country setting, yet just minutes from town and

  Karen McGinty Hatcher Realty Services, Inc. Branford

  591 SW San Pedro Ave, Mayo, FL 32066
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  /3

  $14,900

  • Land

  0 SE Suwannee Trail, Obrien, FL 32071

  WOW....A Really Great Deal, 2 parcels of land for the price of one! Lots 17, 18, 19, and 20 in SE Suwannee Heights Subdivision and Lots 21, 22, 23, and 24 in Suwannee Estates Subdivision. Lots are in Flood Zone X, rural, and wooded. Roads leading to property is overgrown and a path will have to be cleared to access the property. Seller is open to short term owner financing with 20% down.

  Crystal Bochnia Madison Realty Group, LLC

  0 SE Suwannee Trail, Obrien, FL 32071
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  /14

  $149,500

  • Land
  • 50 Acres
  • $2,990 per Acre

  0 W US Hwy 27 Unit 795887, Mayo, FL 32066

  50 acres of prime hunting land located just off Hwy 27 in Mayo! This expansive tract has recently had the timber harvested, making it a blank canvas ready for replanting or customizing to fit your needs. Surrounded by natural habitat and abundant with wildlife, this property is ideal for hunting, recreation, or future timber investment. With easy access from a main highway and plenty of space to

  Dewey Hatcher Hatcher Realty Services, Inc. Steinhatchee

  0 W US Hwy 27 Unit 795887, Mayo, FL 32066
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  /4

  $25,000

  • Land
  • 1.01 Acres
  • $24,752 per Acre

  3 Tbd, Mayo, FL 32066

  Vacant lot located just outside the city limits of Mayo in Lafayettee County

  3 Tbd, Mayo, FL 32066
• 

  

  /19

  $109,000

  • Land
  • 14.55 Acres
  • $7,491 per Acre

  TBD SE County Road 360, Mayo, FL 32066

  14.55 acres of diverse North Florida woodlands with highway frontage in Lafayette County — the rare combination of true privacy and easy access in one tract. The southeastern portion of the property sits high and dry right along the highway, offering an ideal homesite. Step back from the road and the land transitions into a beautiful mixed timber stand — pine, oak, maple, sweet gum, and cypress —

  Tucker Smith United Country Smith & Associates

  TBD SE County Road 360, Mayo, FL 32066
• 

  

  /17

  $329,000

  • 3 Beds
  • 2 Baths
  • 1,152 Sq Ft

  TBD NE Rowan Rd, Mayo, FL 32066

  This 47-acre parcel, split from a larger 130+ acre property offers a rare chance to own a mostly open, pasture-style property with unlimited potential. A mobile home on site, in need of some rehabilitation, provides an opportunity for restoration, temporary housing, or future rental use while you bring your vision to life. The original 1930s farmhouse is also onsite, a gentle reminder of the

  Chelsea Morgan Focus Real Estate Group, Inc.

  TBD NE Rowan Rd, Mayo, FL 32066
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  /24

  $160,000

  • Land
  • 3.08 Acres
  • $51,948 per Acre

  TBD NE Trestle Dr (4 Lots), Mayo, FL 32066

  Uncover this stunning 3-acre property for sale, just a stone's throw from the iconic Suwannee River! This tranquil and private oasis is brimming with wildlife and offers the perfect backdrop for your dream home—whether a custom-built residence, a mobile home, or a delightful recreational getaway. With two convenient boat ramps nearby, you can easily indulge in kayaking and boating adventures.

  Elizabeth Phillips DANIEL CRAPPS AGENCY, INC

  TBD NE Trestle Dr (4 Lots), Mayo, FL 32066
• 

  

  /4

  $64,900

  • Land
  • 5.67 Acres
  • $11,446 per Acre

  0 W Tbd Main St Unit 130885, Mayo, FL 32066

  5.67 Acres in Mayo, Florida – Prime Location Near Harrington Community Center Discover the perfect opportunity to own 5.67 beautiful acres in the charming town of Mayo, Florida. Ideally situated next to the Harrington Community Center, this property offers both convenience and small-town appeal. Enjoy close proximity to local shopping, schools, churches, and everyday essentials while still

  Michael DeGeorge POOLE REALTY INC.

  0 W Tbd Main St Unit 130885, Mayo, FL 32066

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