9

Melrose, FL Homes for Rent

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    $1,600 Per Month

    • 1 Bed
    • 1 Bath
    • 1,060 Sq Ft
    • Apartment for Rent

    1464 SE County Road 21b, Melrose, FL 32666

    Come live on Lake Santa Fe with an awesome lake view. Lake access included but NO DOCK ACCESS. Nice quiet place to live. Office space with lake view for working from home. Utilities are included except electric and cable. Sorry no pets,.

    Freddie Stephens AMERICAN DREAM OF NORTHEAST FLORIDA

    1464 SE County Road 21b, Melrose, FL 32666
  • /24

    $2,250 Per Month

    • 4 Beds
    • 3 Baths
    • 2,240 Sq Ft
    • House for Rent

    7662 Monongahela Ave, Keystone Heights, FL 32656

    Enjoy plenty of space inside and out with this spacious 4 bedroom, 3 bath rental home situated on over 2 acres. The home also features two additional flex rooms, perfect for a home office, playroom, hobby room, or extra living space. Relax outdoors on the 8x12 front deck or the large 30x16 back deck. The property is fully fenced, offering plenty of room for pets and outdoor enjoyment. Located on

    7662 Monongahela Ave, Keystone Heights, FL 32656
  • /30

    $1,485 Per Month

    • 3 Beds
    • 2 Baths
    • 1,400 Sq Ft
    • Property for Rent

    932 SE 40th Place, Melrose, FL 32666

    WELCOME HOME !!! Spacious 3-bedroom, 2 bath double-wide situated on a half an acre quiet street. Incredibly clean and beautiful decor to match all your furnishings. Enjoy a peaceful setting surrounded by mature trees, with plenty of outdoor space and room to relax. Comfortable, inviting, and ready to call home!!

    Lynde Jones LA ROSA REALTY LLC

    932 SE 40th Place, Melrose, FL 32666
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    $2,595 Per Month

    • 3 Beds
    • 2.5 Baths
    • 2,945 Sq Ft
    • House for Rent

    436 SE 4th Ave, Melrose, FL 32666

    Charming Lake Santa Fe Canal Basin Home – Melrose, FL. Welcome to this beautiful 3-bedroom, 2.5-bath home located in the tranquil Lake Santa Fe Canal Basin community of Melrose. This spacious two-story home also features a versatile bonus room above the garage complete with a half bath, perfect for a guest suite, office, or hobby space. Enjoy a short boat ride to the open waters of Lake Santa

    436 SE 4th Ave, Melrose, FL 32666
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    $1,800 Per Month

    • 3 Beds
    • 2 Baths
    • 1,296 Sq Ft
    • House for Rent

    7934 Sunnybrook Rd, Melrose, FL 32666

    Views out EVERY window. Water pond area in back. TONS of incredible upgrades to the house. Quiet. Tranquil. Down a quiet private path awaits your new home.

    Steven Koleno BEYCOME OF FLORIDA LLC

    7934 Sunnybrook Rd, Melrose, FL 32666
  • /24

    $1,395 Per Month

    • 3 Beds
    • 2 Baths
    • 1,200 Sq Ft
    • Property for Rent

    877 SE 38th Way, Melrose, FL 32666

    Beautiful 3BR/2BA Home on 1⁄2 Acre –Clean, Spacious & Move-In Ready!Looking for a home you’ll be proud to live in? Thisbeautifully maintained 3-bedroom, 2-bath home offersthe perfect combination of comfort, space, and privacy.Situated on a peaceful 1⁄2-acre lot with gorgeous matureshade trees, this home features a bright, open floor planthat’s perfect for relaxing,

    Lynde Jones LA ROSA REALTY LLC

    877 SE 38th Way, Melrose, FL 32666
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    $3,200 Per Month

    • 2 Beds
    • 2 Baths
    • 2,057 Sq Ft
    • House for Rent

    22826 NE 69th Ave, Melrose, FL 32666

    Beautiful 2024 custom built home for rent on Lake Santa Fe! This 2 bedroom, 2 bath home offers 2,057 sq. ft. of living space, approximately 82 feet of waterfront and a huge 4-car garage. The open living and kitchen area has impressive 22-foot ceilings and large sliding glass doors with beautiful lake views that lead out to a 62-foot covered porch. The kitchen features granite countertops,

    DEBBIE BEALS FLORIDA HOMES REALTY & MORTGAGE PROPERTY MANAGEMENT

    22826 NE 69th Ave, Melrose, FL 32666

Why Live in Melrose

Melrose, Florida, is a rural community in north-central Florida, spanning parts of Putnam, Clay, Alachua and Bradford counties. Known for its Victorian-era historic district and the expansive Lake Santa Fe, Melrose is a hub for recreational activities such as boating, fishing and kayaking. The area is about 18 miles east of Gainesville, providing a convenient route via Florida state Road 26. Housing in Melrose ranges from historic 19th-century homes to ranch-styles and waterfront properties. The community is noted for its vibrant arts scene, highlighted by events like the First Friday Art Walk at Mossman Hall. Local attractions include the Blue Water Bay seafood restaurant and the historic Chiappini Gulf Station, which serves as a community gathering spot. Melrose is served by four school districts, with Clay and Alachua counties having the highest ratings. The area's natural beauty and laid-back lifestyle attract artists and part-time residents, while its proximity to Gainesville draws professionals from the University of Florida and regional healthcare centers. Nearby, Palatka has hosted Bassmaster tournament events, underscoring the region's reputation for fishing.

Frequently Asked Questions

How much does it cost to rent a home in Melrose, FL?
The median rent for a home in Melrose, FL is $1,800 per month, though prices vary by neighborhood, size, and property type. As of September 2026, single-family homes tend to be the most affordable option.
How much do you need to make to afford rent in Melrose, FL?
To comfortably afford the median rent in Melrose, FL, a household needs to earn roughly $72,000 per year. This is based on the common guideline that households should spend no more than 30% of gross income on housing. Most landlords require monthly household income of at least 3x the monthly rent, and with a median rent of $1,800 per month in Melrose, FL, renters typically need to show $5,400 per month in gross income to qualify. Actual affordability will vary depending on household debts, other living expenses, and overall budget.
Is it more affordable to rent or buy in Melrose, FL?
In Melrose, FL, the price-to-rent ratio is 17.8, which generally favors renting. This ratio divides the median home price by the annual median rent: below 15 typically favors buying, 15 to 20 is balanced, and above 20 typically favors renting. Your finances, how long you plan to stay, and costs like mortgage rates, taxes, and maintenance all factor into the decision.
What neighborhoods in Melrose, FL are best for renting a home?
The best neighborhood for renting in Melrose, FL depends on your priorities: commute, walkability, budget, and lifestyle all play a role. Popular areas for renting a home include Duckpond, Pleasant Street, Kirkwood and Downtown Gainesville, each with its own character and price range.

Rental Home Trends

Number of Homes for Rent
9
Median Rent
$1,800
Median Single Family Home Rent
$1,975
How to Rent a Home