59

New Madrid County MO Homes for Sale

Section Image Section Image
  • /2

    $30,000

    • 2,244 Sq Ft

    430 N 3rd St, Lilbourn, MO 63862

    Multi use building

    Agent Photo

    Thomas Orosz

    Keller Williams Realty St. Louis

    (573) 763-2619

    430 N 3rd St, Lilbourn, MO 63862
  • /10

    $1,200,000

    • Land
    • 22.84 Acres
    • $52,539 per Acre

    2338 S Acres Dr, Sikeston, MO 63801

    Strategically positioned just off Exit 69 on Interstate 55 North, this prime, high-traffic vacant ground spans over 22 acres and offers exceptional visibility, constant drive-by exposure, and effortless ingress/egress. Surrounded by established retailers and a strong daytime population, it’s ideal for retail, restaurant/QSR, service, medical, or professional uses.

    Agent Photo

    Ronnie Cline Jr

    Poplar Bluff Realty Inc

    (573) 779-4886

    2338 S Acres Dr, Sikeston, MO 63801
  • /6

    $2,206,160

    • Land
    • 270 Acres
    • $8,171 per Acre

    000 Cr 820 Unit Matthews, Matthews, MO 63867

    Contact JR Goodin (573) 620-3264 .This productive row crop farm in New Madrid County, Missouri, offers a premium investment opportunity for those seeking a balance of agricultural income and recreational utility. The property consists of approximately 270+/- tillable acres of fertile ground, with two center pivots and a dedicated high-capacity well. Located off CR 820 near Matthews, the

    Rooted Co. Rooted Real Estate & Auction Co.

    000 Cr 820 Unit Matthews, Matthews, MO 63867
  • /13

    $3,931,845

    • Land
    • 460 Acres
    • $8,547 per Acre

    000 Cr 706, Matthews, MO 63867

    Contact JR Goodin (573) 620-3264 .This productive row crop farm, 460+/- acres in New Madrid County Missouri, represents a high-quality agricultural asset with excellent dual-purpose utility. The farm is fully equipped for consistent production, featuring two center pivots serviced by their own respective well and diesel power units, ensuring water and yield stability regardless of

    Rooted Co. Rooted Real Estate & Auction Co.

    000 Cr 706, Matthews, MO 63867
  • /6

    $821,120

    • Land
    • 100 Acres
    • $8,211 per Acre

    000 Cr 714, Matthews, MO 63867

    Contact JR Goodin (573) 620-3264 .This productive row crop farm, 100+/- acres in New Madrid County Missouri, represents a quality agricultural asset. The farm is not irrigated, but its heavy soils retain moisture for the hot growing months. Its location in the Mississippi River Delta Flyway makes it a very desirable spot for migrating waterfowl. This farm is an area between Yellow Dog

    Rooted Co. Rooted Real Estate & Auction Co.

    000 Cr 714, Matthews, MO 63867
  • /34

    $4,570,410

    • Land
    • 460 Acres
    • $9,936 per Acre

    000 State Highway 80, East Prairie, MO 63845

    Contact JR Goodin (573) 620-3264 .This productive row crop farm, 460+/- acres just east of East Prairie in Mississippi County Missouri, represents a high-quality agricultural asset with excellent dual-purpose utility. The farm is fully equipped for consistent production, with one half-mile center pivot serviced by its own high capacity well and a 6 cylinder John Deere diesel power unit,

    Rooted Co. Rooted Real Estate & Auction Co.

    000 State Highway 80, East Prairie, MO 63845
  • /2

    $15,000

    • Land
    • 8,712 Sq Ft
    • $75,000 per Acre

    807 Bollweevil Blvd, Sikeston, MO 63801

    This vacant residential lot is ready for you to build on, and priced to help you get started quickly. Covenants and restrictions are in place to help protect your investment. Located inside Sikeston City Limits. Additional Rooms: In Platted Subdv.

    Tim Merideth Century 21 Premiere Realty

    807 Bollweevil Blvd, Sikeston, MO 63801
  • /43

    $329,900

    $20K PRICE DROP
    • 5 Beds
    • 3.5 Baths
    • 3,019 Sq Ft

    130 Saint Mark Ln, New Madrid, MO 63869

    Harvey Graham HARVEY GRAHAM & ASSOC. REALTY

    130 Saint Mark Ln, New Madrid, MO 63869
  • /2

    $15,000

    • Land
    • 12,196 Sq Ft
    • $53,571 per Acre

    801 Bollweevil Blvd, Sikeston, MO 63801

    This vacant residential lot is ready for you to build on, and priced to help you get started quickly. Covenants and restrictions are in place to help protect your investment. Located inside Sikeston City Limits. Additional Rooms: In Platted Subdv.

    Tim Merideth Century 21 Premiere Realty

    801 Bollweevil Blvd, Sikeston, MO 63801
  • /2

    $15,000

    • Land
    • 9,147 Sq Ft
    • $71,429 per Acre

    811 Cotton Ridge Dr, Sikeston, MO 63801

    This vacant residential lot is ready for you to build on, and priced to help you get started quickly. Covenants and restrictions are in place to help protect your investment. Located inside Sikeston City Limits. Additional Rooms: In Platted Subdv.

    Tim Merideth Century 21 Premiere Realty

    811 Cotton Ridge Dr, Sikeston, MO 63801
  • /15

    $135,000

    $15K PRICE DROP
    • 2 Beds
    • 2 Baths
    • 1,272 Sq Ft

    4499 State Highway 153, Gideon, MO 63848

    If you’ve been looking for space outside of town with the upgrades already handled—this is it. Situated on almost an acre, this updated home offers peaceful country living with the convenience you want. The 30x40 shop sits on a 40x40 concrete pad and gives you the flexibility for a workshop, hobbies, or storage. Hard to find this kind of setup with this much versatility.

    Kaydee Mitchell EDGE Realty, ERA Powered

    4499 State Highway 153, Gideon, MO 63848
  • /2

    $15,000

    • Land
    • 8,712 Sq Ft
    • $75,000 per Acre

    811 Bollweevil Blvd, Sikeston, MO 63801

    This vacant residential lot is ready for you to build on, and priced to help you get started quickly. Covenants and restrictions are in place to help protect your investment. Located inside Sikeston City Limits. Additional Rooms: In Platted Subdv.

    Tim Merideth Century 21 Premiere Realty

    811 Bollweevil Blvd, Sikeston, MO 63801
  • /41

    $165,000

    • 2 Baths
    • 16,847 Sq Ft

    110 N Main St, Gideon, MO 63848

    Prime opportunity on 8.20± acres in Gideon, MO with direct frontage on North Main Street. This property features a 16,800± sq ft functional warehouse currently in use, offering an open floor plan, steel frame construction, concrete floors, and multiple access points including overhead, sliding, and roll-up doors. The site also includes a loading dock and loading well, making it well

    Kaydee Mitchell EDGE Realty, ERA Powered

    110 N Main St, Gideon, MO 63848
  • /59

    $299,000

    $100K PRICE DROP
    • 5 Beds
    • 3.5 Baths
    • 4,392 Sq Ft

    22 Greenbriar Dr, New Madrid, MO 63869

    BRAND NEW ROOF AND HVAC!!!!Welcome to your dream home—where rustic elegance meets comfort. Situated on a generous, beautifully landscaped lot in one of the area’s most sought-after neighborhoods, this spacious residence offers the perfect blend of privacy, character, and convenience. From the moment you step inside, you'll be captivated by the warm wood finishes, exposed beams, and soaring

    Lawren McMullan EDGE Realty, ERA Powered

    22 Greenbriar Dr, New Madrid, MO 63869
  • /21

    $207,500

    • 3 Beds
    • 2 Baths
    • 1,753 Sq Ft

    2112 County Highway 264, Gideon, MO 63848

    Where country peace meets modern style! This fully renovated 3-bedroom, 2-bath ranch boasts 1,753 sq. ft. of move-in-ready space. Bright, open rooms flow to a kitchen with a butcher block island, perfect for cooking, homework, or coffee with a view. Enjoy a leased security system, a new front deck hand railing, and thoughtful updates throughout. Outside, 1.58 acres offer space to roam, plus a

    Dawn Simpson Delta Realty, LLC

    2112 County Highway 264, Gideon, MO 63848
  • /2

    $15,000

    • Land
    • 12,196 Sq Ft
    • $53,571 per Acre

    800 Cotton Ridge Dr, Sikeston, MO 63801

    This vacant residential lot is ready for you to build on, and priced to help you get started quickly. Covenants and restrictions are in place to help protect your investment. Located inside Sikeston City Limits. Additional Rooms: In Platted Subdv.

    Tim Merideth Century 21 Premiere Realty

    800 Cotton Ridge Dr, Sikeston, MO 63801
  • /36

    $250,000

    $10K PRICE DROP
    • 3 Beds
    • 3 Baths
    • 1,492 Sq Ft

    119 Depro Ave, Sikeston, MO 63801

    Set on a spacious 0.72-acre corner lot just outside Sikeston, this property features a brand-new 30x40 pole barn, a large shed, and a garage, giving you more covered storage and workspace.Inside, the raised ranch layout offers 1,492 square feet with 3 bedrooms and 3 full bathrooms across two levels. Fresh updates throughout and a new roof mean the big-ticket items are already done. Central

    Jessica Moore EXP Realty, LLC

    119 Depro Ave, Sikeston, MO 63801
  • /4

    $500,000

    1201 Lawrence St, Sikeston, MO 63801

    1.24 acres of commercial land located on the corner of Stallcup Drive and Lawrence Street. This lot is located beside a 60 unit apartment complex; and there is a Lowe's, JC Penney and Taco Bell within walking distance. Concrete streets. Located in New Madrid County, Sikeston city limits. Zoned light industrial.

    Tim Merideth Century 21 Premiere Realty

    1201 Lawrence St, Sikeston, MO 63801
  • /20

    $195,000

    $5K PRICE DROP
    • 3 Beds
    • 2 Baths
    • 1,196 Sq Ft

    308 de Lisle Ave, Portageville, MO 63873

    Looking for a move in ready newer home!? Here it is! This 3 bedroom 2 full bath is an semi open concept with a split floor plan. Perfect for entertaining but privacy for your bedroom retreat. The whole home has tile throughout, double vanity in the primary, patio area, laundry area, and all appliances stay including the refrigerator. Schedule your tour today!!

    Leann Adams Silverthorn Realty, LLC

    308 de Lisle Ave, Portageville, MO 63873
  • /4

    $500,000

    1209 Lawrence St, Sikeston, MO 63801

    Commercial land on a corner lot available for development in Sikeston's busiest retail area. 1.05 acres zoned light industrial is located directly across the street from Wal-Mart. Other major retailers located close by include JC Penney, Goodies, and Lowe's. Located in New Madrid county, Sikeston city limits.

    Tim Merideth Century 21 Premiere Realty

    1209 Lawrence St, Sikeston, MO 63801
  • /37

    $340,000

    • 4 Beds
    • 2 Baths
    • 2,004 Sq Ft

    1132 Pollard Plaza, Sikeston, MO 63801

    Welcome to this beautifully built 2024 home in Sikeston offering the perfect blend of modern design and everyday comfort. This stunning property features 4 spacious bedrooms, 2 full bathrooms, and 2,004 square feet of finished living space, providing plenty of room for both relaxing and entertaining.Situated on a desirable corner lot, this wonderful brick home offers great curb appeal along

    Jakahran Johnson EXP Realty, LLC

    1132 Pollard Plaza, Sikeston, MO 63801
  • /2

    $150,000

    • Land
    • 30,230 Sq Ft
    • $216,138 per Acre

    0 E 1st St, Portageville, MO 63873

    Kaydee Mitchell EDGE Realty, ERA Powered

    0 E 1st St, Portageville, MO 63873
  • /11

    $40,000

    • 2 Beds
    • 1 Bath
    • 832 Sq Ft

    944 Brush Prairie Rd, New Madrid, MO 63869

    This two bedroom one bath home is the ultimate value opportunity at this listed price of $40,000. The interior features a smart, no waste layout that makes the home feel much larger than the actual square footage. For added convenience, the laundry area is located in the kitchen making it easy to manage. The exterior features a metal roof, a major asset for long-term maintenance. The home is

    Reida Kimes Century 21 Premiere Realty

    944 Brush Prairie Rd, New Madrid, MO 63869
  • /4

    $195,000

    • Land
    • 31,363 Sq Ft
    • $270,833 per Acre

    116 Hospitality Dr, Sikeston, MO 63801

    Vacant, level lot. Not in the flood plain.

    Larry Lindsey Century 21 Premiere Realty

    116 Hospitality Dr, Sikeston, MO 63801
  • /2

    $15,000

    • Land
    • 10,454 Sq Ft
    • $62,500 per Acre

    810 Cotton Ridge Dr, Sikeston, MO 63801

    This vacant residential lot is ready for you to build on, and priced to help you get started quickly. Covenants and restrictions are in place to help protect your investment. Located inside Sikeston City Limits. Additional Rooms: In Platted Subdv.

    Tim Merideth Century 21 Premiere Realty

    810 Cotton Ridge Dr, Sikeston, MO 63801
  • /4

    $69,900

    $5K PRICE DROP
    • 3 Beds
    • 1 Bath
    • 1,078 Sq Ft

    304 N Anderson Ave, Gideon, MO 63848

    This affordable home was completely updated three years ago. Here are a few of the recent updates: new water heater, new dishwasher, and new flooring. This charming 3-bedroom home has one full bathroom, spacious laundry room, and a partially fenced yard. This home is low maintenance, updated, and priced to move.

    Cindy Thomas Image Realty

    304 N Anderson Ave, Gideon, MO 63848
  • /2

    $10,000

    • Land
    • 0 Sq Ft

    301 Warren Ave, Portageville, MO 63873

    Judy Scherer HARVEY GRAHAM & ASSOC. REALTY

    301 Warren Ave, Portageville, MO 63873
  • /2

    $25,000

    • Land
    • 0 Sq Ft

    201 W 8th St, Portageville, MO 63873

    201 West 8th203 West 8th709 Meatte

    Judy Scherer HARVEY GRAHAM & ASSOC. REALTY

    201 W 8th St, Portageville, MO 63873
  • /15

    $3,931,845

    000 Cr 706 Unit 3, Matthews, MO 63867

    This productive row crop farm, 460+/- acres in New Madrid County Missouri, represents a high-quality agricultural asset with excellent dual-purpose utility. The farm is fully equipped for consistent production, featuring two center pivots serviced by their own respective well and diesel power units, ensuring water and yield stability regardless of seasonal rainfall. Its location in the

    John Goodin Rooted Real Estate & Auction Co.

    000 Cr 706 Unit 3, Matthews, MO 63867
  • /11

    $129,900

    $10K PRICE DROP
    • 3 Beds
    • 2 Baths
    • 1,428 Sq Ft

    1846 County Highway 524, Parma, MO 63870

    Enjoy peaceful country living just outside of town in this 3 bedroom, 2 bath home situated on 5.95 acres with wide-open views and beautiful sunsets. Offering 1,428 sq ft of living space, this home features an open-concept layout with spacious living and dining areas, a functional kitchen with ample cabinet storage, and a split-bedroom design. The primary suite includes a private bath, while two

    Scott Harrison Delta Realty, LLC

    1846 County Highway 524, Parma, MO 63870
  • /7

    $821,120

    000 Cr 714 Unit 4, Matthews, MO 63867

    This productive row crop farm, 100+/- acres in New Madrid County Missouri, represents a quality agricultural asset. The farm is not irrigated, but its heavy soils retain moisture for the hot growing months. Its location in the Mississippi River Delta Flyway makes it a very desirable spot for migrating waterfowl. This farm is an area between Yellow Dog and the infamous Gee Bottoms, southwest of

    John Goodin Rooted Real Estate & Auction Co.

    000 Cr 714 Unit 4, Matthews, MO 63867
  • /35

    $279,900

    $45K PRICE DROP
    • 4 Beds
    • 2.5 Baths
    • 2,935 Sq Ft

    101 Saint Matthew Ln, New Madrid, MO 63869

    Beautiful, well built, move in ready, 2935 sq. ft., two story, brick home featuring 3 bedrooms upstairs and a large master bedroom downstairs with large bathroom and lots of storage. Located on a corner lot.

    Harvey Graham HARVEY GRAHAM & ASSOC. REALTY

    101 Saint Matthew Ln, New Madrid, MO 63869
  • /13

    $59,900

    $6K PRICE DROP
    • 2 Beds
    • 2 Baths
    • 1,120 Sq Ft

    806 Dawson Rd, New Madrid, MO 63869

    Looking for an affordable path to homeownership or your next investment opportunity? This 2-bedroom, 2-bath modular home offers solid value at a price point that is hard to find in today’s market. Situated on a 0.16-acre lot, this home features a functional layout with a spacious living area, large kitchen with plenty of cabinet space, and a split-bedroom design that provides privacy. The home

    Nick White HARVEY GRAHAM & ASSOC. REALTY

    806 Dawson Rd, New Madrid, MO 63869
  • /2

    $8,500

    • Land
    • 7,248 Sq Ft
    • $51,082 per Acre

    Lot 6 Fisher Dr, Morehouse, MO 63868

    Nice corner lot located at the intersection of Fisher Drive and Spruce Street in Morehouse, Missouri. This level lot offers excellent access and visibility and would make a great home site or investment property. City utilities are available nearby (buyer to verify). Convenient location within a quiet residential area, just a short drive to Sikeston and area amenities.

    Stephanie Anderson SMG Realty

    Lot 6 Fisher Dr, Morehouse, MO 63868
  • /2

    $12,500

    • Land
    • 0 Sq Ft

    107 Eighth W, Portageville, MO 63873

    Judy Scherer HARVEY GRAHAM & ASSOC. REALTY

    107 Eighth W, Portageville, MO 63873
  • /3

    $24,900

    • 2 Beds
    • 1 Bath
    • 898 Sq Ft

    950 2nd St, New Madrid, MO 63869

    Christina Essner EXP Realty, LLC

    950 2nd St, New Madrid, MO 63869
  • /2

    $15,000

    • Land
    • 8,712 Sq Ft
    • $75,000 per Acre

    809 Bollweevil Blvd, Sikeston, MO 63801

    This vacant residential lot is ready for you to build on, and priced to help you get started quickly. Covenants and restrictions are in place to help protect your investment. Located inside Sikeston City Limits. Additional Rooms: In Platted Subdv.

    Tim Merideth Century 21 Premiere Realty

    809 Bollweevil Blvd, Sikeston, MO 63801
  • /13

    $59,900

    $6K PRICE DROP
    • 2 Beds
    • 2 Baths
    • 1,120 Sq Ft

    808 Dawson Rd, New Madrid, MO 63869

    Looking for an affordable path to homeownership or your next investment opportunity? This 2-bedroom, 2-bath modular home offers solid value at a price point that is hard to find in today’s market. Situated on a 0.16-acre lot, this home features a functional layout with a spacious living area, large kitchen with plenty of cabinet space, and a split-bedroom design that provides privacy. The home

    Nick White HARVEY GRAHAM & ASSOC. REALTY

    808 Dawson Rd, New Madrid, MO 63869
  • /23

    $275,000

    • 5 Beds
    • 2.5 Baths
    • 3,230 Sq Ft

    858 Cambridge Dr, Sikeston, MO 63801

    First time on the market! Proudly offered by the original owner and builder, this exceptional home showcases quality craftsmanship and meticulous care throughout. No detail was overlooked in the construction of this spacious 3-bedroom, 2 bath residence, featuring a finished basement with 2 additional bedrooms, a half bath, and abundant storage space. With over 3,000 square feet of total living

    Rene Church Century 21 Premiere Realty

    858 Cambridge Dr, Sikeston, MO 63801
  • /19

    $89,500

    $6K PRICE DROP
    • 2 Beds
    • 1 Bath
    • 1,045 Sq Ft

    302 Marshall St, Sikeston, MO 63801

    Welcome to this cozy 2 bed, 1 bath home on a desirable corner lot! Featuring a new heating unit, this property offers comfort and peace of mind. Whether you're a first-time buyer, looking to downsize, or searching for your next investment property, this home checks all the boxes. Affordable, manageable, and full of potential!

    Lynsey Perry Silverthorn Realty, LLC

    302 Marshall St, Sikeston, MO 63801

Showing Results 1 - 40, Page 1 of 2

How to Buy a Home How to Finance a Home How to Sell a Home