New Madrid County MO Homes for Sale

/10
$1,200,000
- Land
- 22.84 Acres
- $52,539 per Acre
2338 S Acres Dr, Sikeston, MO 63801

Strategically positioned just off Exit 69 on Interstate 55 North, this prime, high-traffic vacant ground spans over 22 acres and offers exceptional visibility, constant drive-by exposure, and effortless ingress/egress. Surrounded by established retailers and a strong daytime population, it’s ideal for retail, restaurant/QSR, service, medical, or professional uses.

Ronnie Cline Jr

Poplar Bluff Realty Inc

2338 S Acres Dr, Sikeston, MO 63801
/26
$249,900
- 3 Beds
- 2 Baths
- 1,594 Sq Ft
1010 Pine St, Sikeston, MO 63801

This beautifully updated home is truly turnkey, with fresh interior paint, updated lighting, and refreshed landscaping completed within the last year. Every bedroom features a walk-in closet, offering exceptional storage throughout. The primary suite stands out with its elegant chandelier, spacious walk-in closet, and a newly renovated bathroom. The kitchen includes a large island, custom-painted

Cheryl Rushing

Integrity Realty Partners

1010 Pine St, Sikeston, MO 63801
/6
$2,206,160
- Land
- 270 Acres
- $8,171 per Acre
000 Cr 820 Unit Matthews, Matthews, MO 63867

Contact JR Goodin (573) 620-3264 .This productive row crop farm in New Madrid County, Missouri, offers a premium investment opportunity for those seeking a balance of agricultural income and recreational utility. The property consists of approximately 270+/- tillable acres of fertile ground, with two center pivots and a dedicated high-capacity well. Located off CR 820 near Matthews, the

Rooted Co. Rooted Real Estate & Auction Co.

000 Cr 820 Unit Matthews, Matthews, MO 63867
/13
$3,931,845
- Land
- 460 Acres
- $8,547 per Acre
000 Cr 706, Matthews, MO 63867

Contact JR Goodin (573) 620-3264 .This productive row crop farm, 460+/- acres in New Madrid County Missouri, represents a high-quality agricultural asset with excellent dual-purpose utility. The farm is fully equipped for consistent production, featuring two center pivots serviced by their own respective well and diesel power units, ensuring water and yield stability regardless of

Rooted Co. Rooted Real Estate & Auction Co.

000 Cr 706, Matthews, MO 63867
/6
$821,120
- Land
- 100 Acres
- $8,211 per Acre
000 Cr 714, Matthews, MO 63867

Contact JR Goodin (573) 620-3264 .This productive row crop farm, 100+/- acres in New Madrid County Missouri, represents a quality agricultural asset. The farm is not irrigated, but its heavy soils retain moisture for the hot growing months. Its location in the Mississippi River Delta Flyway makes it a very desirable spot for migrating waterfowl. This farm is an area between Yellow Dog

Rooted Co. Rooted Real Estate & Auction Co.

000 Cr 714, Matthews, MO 63867
/34
$4,570,410
- Land
- 460 Acres
- $9,936 per Acre
000 State Highway 80, East Prairie, MO 63845

Contact JR Goodin (573) 620-3264 .This productive row crop farm, 460+/- acres just east of East Prairie in Mississippi County Missouri, represents a high-quality agricultural asset with excellent dual-purpose utility. The farm is fully equipped for consistent production, with one half-mile center pivot serviced by its own high capacity well and a 6 cylinder John Deere diesel power unit,

Rooted Co. Rooted Real Estate & Auction Co.

000 State Highway 80, East Prairie, MO 63845
/2
$15,000
- Land
- 8,712 Sq Ft
- $75,000 per Acre
807 Bollweevil Blvd, Sikeston, MO 63801

This vacant residential lot is ready for you to build on, and priced to help you get started quickly. Covenants and restrictions are in place to help protect your investment. Located inside Sikeston City Limits. Additional Rooms: In Platted Subdv.

Tim Merideth Century 21 Premiere Realty

807 Bollweevil Blvd, Sikeston, MO 63801
/20
$155,000
- 3 Beds
- 1 Bath
- 1,720 Sq Ft
404 N Main St, Gideon, MO 63848

Welcome to 404 N. Main St. in Gideon, Missouri—a beautifully remodeled ranch-style home that blends timeless charm with modern comfort. Originally built in 1942, this inviting 3-bedroom, 1-bath residence has been thoughtfully updated to offer today's functionality while preserving its warm, country-inspired character. Chic finishes, contemporary appliances, and carefully selected design touches

Devin Barnes Trust Realty, LLC

404 N Main St, Gideon, MO 63848
/8
$90,000
- 1,415 Sq Ft
301/303 King Ave, Portageville, MO 63873

Investor Opportunity in the Downtown Area! Located next to the Post Office, this property package offers a fantastic opportunity for investors or owner-occupants looking to build equity while generating rental income. This unique offering includes two single-family homes on one parcel. 301 King features 3 bedrooms and 1 bathroom, while 303 King offers 2 bedrooms and 1 bathroom. With two homes on

Christina Essner EXP Realty, LLC

301/303 King Ave, Portageville, MO 63873
/2
$229,900
- 5 Beds
- 3 Baths
- 3,010 Sq Ft
1001 Davis St, New Madrid, MO 63869

Welcome to this 5-bedroom, 3-bath home offering approximately 3,010 square feet of living space on three city lots in the heart of New Madrid. Rich in character and classic architectural details, this impressive 11⁄2-story home combines timeless charm with the space and functionality today's buyers are looking for. From the inviting front porch and distinctive dormers to the spacious interior,

Nick White HARVEY GRAHAM & ASSOC. REALTY

1001 Davis St, New Madrid, MO 63869
/2
$15,000
- Land
- 12,196 Sq Ft
- $53,571 per Acre
801 Bollweevil Blvd, Sikeston, MO 63801

This vacant residential lot is ready for you to build on, and priced to help you get started quickly. Covenants and restrictions are in place to help protect your investment. Located inside Sikeston City Limits. Additional Rooms: In Platted Subdv.

Tim Merideth Century 21 Premiere Realty

801 Bollweevil Blvd, Sikeston, MO 63801
/12
$450,000
- Land
- 2.93 Acres
- $153,584 per Acre
1168 Stallcup Dr, Sikeston, MO 63801

Located on the south end of town next to Sikeston’s vibrant, commercial area. Close-by retailers include Wal-mart, Lowe’s, and Ollies. Restaurants include Taco Bell, Colton’s Steakhouse, and Applebee’s. 3 national hotels are close by, all driving traffic count to this part of town.

Tim Merideth Century 21 Premiere Realty

1168 Stallcup Dr, Sikeston, MO 63801
/2
$15,000
- Land
- 9,147 Sq Ft
- $71,429 per Acre
811 Cotton Ridge Dr, Sikeston, MO 63801

This vacant residential lot is ready for you to build on, and priced to help you get started quickly. Covenants and restrictions are in place to help protect your investment. Located inside Sikeston City Limits. Additional Rooms: In Platted Subdv.

Tim Merideth Century 21 Premiere Realty

811 Cotton Ridge Dr, Sikeston, MO 63801
/20
$260,000
- 3 Beds
- 3 Baths
- 2,338 Sq Ft
914 Pine St, Sikeston, MO 63801

Wonderful 3 bedroom / 3 bath home with a basement, garage and a storage building. The best feature is a screened in porch, if you are an outdoors person. This location is convenient to shopping, schools and more. When you enter this home you will see that is is great for entertaining or a big family. The large great room will hold ample furniture and there is also a den in the basement for

allen basham EXP Realty, LLC

914 Pine St, Sikeston, MO 63801
/2
$15,000
- Land
- 8,712 Sq Ft
- $75,000 per Acre
811 Bollweevil Blvd, Sikeston, MO 63801

This vacant residential lot is ready for you to build on, and priced to help you get started quickly. Covenants and restrictions are in place to help protect your investment. Located inside Sikeston City Limits. Additional Rooms: In Platted Subdv.

Tim Merideth Century 21 Premiere Realty

811 Bollweevil Blvd, Sikeston, MO 63801
/41
$165,000
- 2 Baths
- 16,847 Sq Ft
110 N Main St, Gideon, MO 63848

Prime opportunity on 8.20; acres in Gideon, MO with direct frontage on North Main Street. This property features a 16,800; sq ft functional warehouse currently in use, offering an open floor plan, steel frame construction, concrete floors, and multiple access points including overhead, sliding, and roll-up doors. The site also includes a loading dock and loading well, making it well suited for

Kaydee Mitchell EDGE Realty, ERA Powered

110 N Main St, Gideon, MO 63848
/21
$235,000
- 3 Beds
- 2 Baths
- 2,015 Sq Ft
841 Stanford Dr, Sikeston, MO 63801

This home offers plenty of space for a growing family, inside and outside. With over 2000sqft of living space inside you will find 3 bedrooms and 2 updated bathrooms. Updated kitchen with plenty of space for a formal dining room table. A family room and spacious den that offers a beautiful wood burning fireplace. Laundry room with plenty of cabinets for all your storage needs. This home offers a

Breanne Marks Ross Realty

841 Stanford Dr, Sikeston, MO 63801
/4
$88,000
- 864 Sq Ft
306 N Huffman Ave, Portageville, MO 63873

Investor Alert! Check out this cash-flowing property that's ready to help expand your rental portfolio. Whether you're a seasoned investor or just getting started, this income-producing opportunity offers immediate potential and long-term value. With rental income already in place, this property is a great addition for those looking to grow their investment holdings and build wealth through real

Christina Essner EXP Realty, LLC

306 N Huffman Ave, Portageville, MO 63873
/2
$15,000
- Land
- 12,196 Sq Ft
- $53,571 per Acre
800 Cotton Ridge Dr, Sikeston, MO 63801

This vacant residential lot is ready for you to build on, and priced to help you get started quickly. Covenants and restrictions are in place to help protect your investment. Located inside Sikeston City Limits. Additional Rooms: In Platted Subdv.

Tim Merideth Century 21 Premiere Realty

800 Cotton Ridge Dr, Sikeston, MO 63801
/36
$250,000

$10K PRICE DROP
- 3 Beds
- 3 Baths
- 1,492 Sq Ft
119 Depro Ave, Sikeston, MO 63801

Set on a spacious 0.72-acre corner lot just outside Sikeston, this property features a brand-new 30x40 pole barn, a large shed, and a garage, giving you more covered storage and workspace.Inside, the raised ranch layout offers 1,492 square feet with 3 bedrooms and 3 full bathrooms across two levels. Fresh updates throughout and a new roof mean the big-ticket items are already done. Central

Jessica Moore EXP Realty, LLC

119 Depro Ave, Sikeston, MO 63801
/4
$500,000
1201 Lawrence St, Sikeston, MO 63801

1.24 acres of commercial land located on the corner of Stallcup Drive and Lawrence Street. This lot is located beside a 60 unit apartment complex; and there is a Lowe's, JC Penney and Taco Bell within walking distance. Concrete streets. Located in New Madrid County, Sikeston city limits. Zoned light industrial.

Tim Merideth Century 21 Premiere Realty

1201 Lawrence St, Sikeston, MO 63801
/18
$110,000
- 3 Beds
- 2 Baths
- 1,219 Sq Ft
205 S Lunbeck Ave, Gideon, MO 63848

Check out this charming 3 bedroom 2 bathroom home located in the heart of Gideon! This brick home features a metal roof, large kitchen with eat-in dining area & a covered patio leading out to the large backyard. The outbuilding has full electricity.This affordable home is move in ready! If you are ready to stop renting & become a home owner, this is your chance.Call today for your

Melissa Weatherwax Century 21 Semo Realtors

205 S Lunbeck Ave, Gideon, MO 63848
/25
$139,900

$44K PRICE DROP
- 3 Beds
- 2 Baths
- 1,767 Sq Ft
1349 County Hwy, Parma, MO 63870

Country living at its best! Situated on 2.3 acres in the quiet farming community of Risco, Missouri, this remodeled 3-bedroom, 2-bath home offers 1,767 sq. ft. of comfortable living space with beautiful views of surrounding farmland. Features include a durable metal roof, paved circle drive, storm shelter, outbuilding, and a large sunroom perfect for enjoying peaceful country sunsets. Inside,

Thomas Orosz Keller Williams Realty St. Louis

1349 County Hwy, Parma, MO 63870
/20
$195,000

$5K PRICE DROP
- 3 Beds
- 2 Baths
- 1,196 Sq Ft
308 de Lisle Ave, Portageville, MO 63873

Looking for a move in ready newer home!? Here it is! This 3 bedroom 2 full bath is an semi open concept with a split floor plan. Perfect for entertaining but privacy for your bedroom retreat. The whole home has tile throughout, double vanity in the primary, patio area, laundry area, and all appliances stay including the refrigerator. Schedule your tour today!!

Leann Adams Silverthorn Realty

308 de Lisle Ave, Portageville, MO 63873
/4
$500,000
1209 Lawrence St, Sikeston, MO 63801

Commercial land on a corner lot available for development in Sikeston's busiest retail area. 1.05 acres zoned light industrial is located directly across the street from Wal-Mart. Other major retailers located close by include JC Penney, Goodies, and Lowe's. Located in New Madrid county, Sikeston city limits.

Tim Merideth Century 21 Premiere Realty

1209 Lawrence St, Sikeston, MO 63801
/5
$780,000
- Land
111 County Hwy 341, Parma, MO 63870

78.18 FSA acres of highly productive Bootheel row-crop ground in New Madrid County, Missouri. Sharkey silty clay loam ground. Fields are largely open, well-suited to precision farming and good county road access with proximity to grain and cotton markets; local cash-rent and custom-farming options are strong.

Joel King PEOPLES COMPANY

111 County Hwy 341, Parma, MO 63870
/2
$150,000
- Land
- 30,230 Sq Ft
- $216,138 per Acre
0 E 1st St, Portageville, MO 63873

Prime commercial development opportunity in Portageville, Missouri. This fully paved city lot offers outstanding potential for a variety of commercial and investment uses.With excellent accessibility and a highly functional layout, the property is well suited for equipment storage, fleet parking, truck parking, storage units, warehouse development, office space, retail use, contractor

Kaydee Mitchell EDGE Realty, ERA Powered

0 E 1st St, Portageville, MO 63873
/13
$21,900

$8K PRICE DROP
- 4 Beds
- 2 Baths
- 2,244 Sq Ft
430 N 3rd St, Lilbourn, MO 63862

Unique redevelopment opportunity! This 2,244 sq. ft. multi-use building offers endless potential for investors, entrepreneurs, contractors, or those seeking a custom renovation project. Formerly configured as a duplex with two separate entrances, the structure has been gutted to the studs, providing a blank canvas for your vision. The walls remain standing, allowing you to reimagine the layout

Thomas Orosz Keller Williams Realty St. Louis

430 N 3rd St, Lilbourn, MO 63862
/40
$295,000
- 4 Beds
- 3.5 Baths
- 3,297 Sq Ft
200 Clover Ln, Portageville, MO 63873

Come see this beautifully maintained two story residence offering a great blend of space, comfort, and functionality in the heart of Portageville. With 4 spacious bedrooms and 3.5 bathrooms, this home provides plenty of room for friends or family, guests, and entertaining. The floor plan features generous living areas, natural light, and ample storage throughout to keep everything organized. Step

Jenna Hawkins Ritter Real Estate

200 Clover Ln, Portageville, MO 63873
/11
$40,000
- 2 Beds
- 1 Bath
- 832 Sq Ft
944 Brush Prairie Rd, New Madrid, MO 63869

This two bedroom one bath home is the ultimate value opportunity at this listed price of $40,000. The interior features a smart, no waste layout that makes the home feel much larger than the actual square footage. For added convenience, the laundry area is located in the kitchen making it easy to manage. The exterior features a metal roof, a major asset for long-term maintenance. The home is

Reida Kimes Century 21 Premiere Realty

944 Brush Prairie Rd, New Madrid, MO 63869
/4
$195,000
- Land
- 31,363 Sq Ft
- $270,833 per Acre
116 Hospitality Dr, Sikeston, MO 63801

Vacant, level lot. Not in the flood plain.

Larry Lindsey Century 21 Premiere Realty

116 Hospitality Dr, Sikeston, MO 63801
/2
$15,000
- Land
- 10,454 Sq Ft
- $62,500 per Acre
810 Cotton Ridge Dr, Sikeston, MO 63801

This vacant residential lot is ready for you to build on, and priced to help you get started quickly. Covenants and restrictions are in place to help protect your investment. Located inside Sikeston City Limits. Additional Rooms: In Platted Subdv.

Tim Merideth Century 21 Premiere Realty

810 Cotton Ridge Dr, Sikeston, MO 63801
/4
$69,900

$5K PRICE DROP
- 3 Beds
- 1 Bath
- 1,078 Sq Ft
304 N Anderson Ave, Gideon, MO 63848

This affordable home was completely updated three years ago. Here are a few of the recent updates: new water heater, new dishwasher, and new flooring. This charming 3-bedroom home has one full bathroom, spacious laundry room, and a partially fenced yard. This home is low maintenance, updated, and priced to move.

Cindy Thomas Image Realty

304 N Anderson Ave, Gideon, MO 63848
/2
$10,000
- Land
- 0 Sq Ft
301 Warren Ave, Portageville, MO 63873

Judy Scherer HARVEY GRAHAM & ASSOC. REALTY

301 Warren Ave, Portageville, MO 63873
/31
$360,000
000 County Road 732, New Madrid, MO 63869

Turn-Key Waterfowl Tract: 83.17+/- Acres in the Heart of the Mississippi Flyway Location, Location, Location. Positioned less than 2 miles from the Mississippi River in New Madrid County, Missouri, this 83.17+/- acre tract sits squarely in one of the most productive waterfowl corridors in the Midwest. New Madrid County is legendary for holding massive concentrations of waterfowl every single

Landon Carlton Mossy Oak Properties Mozark Re

000 County Road 732, New Madrid, MO 63869
/2
$25,000
- Land
- 0 Sq Ft
201 W 8th St, Portageville, MO 63873

201 West 8th203 West 8th709 Meatte

Judy Scherer HARVEY GRAHAM & ASSOC. REALTY

201 W 8th St, Portageville, MO 63873
/15
$3,931,845
000 Cr 706 Unit 3, Matthews, MO 63867

This productive row crop farm, 460+/- acres in New Madrid County Missouri, represents a high-quality agricultural asset with excellent dual-purpose utility. The farm is fully equipped for consistent production, featuring two center pivots serviced by their own respective well and diesel power units, ensuring water and yield stability regardless of seasonal rainfall. Its location in the

John Goodin Rooted Real Estate & Auction Co.

000 Cr 706 Unit 3, Matthews, MO 63867
/10
$119,900

$20K PRICE DROP
- 3 Beds
- 2 Baths
- 1,428 Sq Ft
1846 County Highway 524, Parma, MO 63870

Enjoy peaceful country living just outside of town in this 3 bedroom, 2 bath home situated on 5.95 acres with wide-open views and beautiful sunsets. Offering 1,428 sq ft of living space, this home features an open-concept layout with spacious living and dining areas, a functional kitchen with ample cabinet storage, and a split-bedroom design. The primary suite includes a private bath, while two

Scott Harrison Delta Realty, LLC

1846 County Highway 524, Parma, MO 63870
/19
$99,000
- 3 Beds
- 1.5 Baths
- 1,331 Sq Ft
300 S Main St, Gideon, MO 63848

Welcome to this updated 3-bedroom, 1.5-bath home located in Gideon, Missouri. This property combines classic character with modern updates at an affordable price point. Recent improvements can be seen throughout the home, including updated flooring, paint, kitchen cabinetry, countertops, fixtures, and more. The spacious living and dining areas provide plenty of room for entertaining, while the

Kaydee Mitchell EDGE Realty, ERA Powered

300 S Main St, Gideon, MO 63848
/18
$45,000

$15K PRICE DROP
- 676 Sq Ft
507/509 Payne Ave, Portageville, MO 63873

Investor Opportunity! This unique package includes two single-family homes and an additional lot, all situated on a quiet road with excellent potential for investors looking to expand their rental portfolio. Both 507 Payne and 509 Payne feature 2 bedrooms and 1 bathroom homes, offering a solid foundation for renovation and future rental income. Whether you're looking to add long-term rentals,

Christina Essner EXP Realty, LLC

507/509 Payne Ave, Portageville, MO 63873

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