4316 Penn Ave Pittsburgh, PA 15224

Located directly across from UPMC Children's Hospital, this well-maintained, family-owned two-unit property combines strong income potential with flexible future use options for both investors or owner-occupants. The first floor commercial space offers exceptional versatility with five dedicated rooms and has previously operated successfully as a retail shop, tea room, and tailor. The layout includes a spacious front room with a half bath and two closets, along with additional flexible use spaces, ideal for office, studio, retail, or service-based businesses. A dedicated area with industrial sinks makes it especially attractive for food preparation or light culinary use. High ceilings enhance the space. Major mechanical updates include Central A/C replaced in Summer 2025 and furnace replaced in Winter 2021.The second-floor residential unit features a 2 bedroom, 1 bathroom apartment with a large private balcony. The kitchen was updated approximately 2 years ago and included refrigerator, stackable W/D, and gas stove. Central A/C was replaced approximately 3 years ago.
The third floor has been utilized exclusively for storage, providing additional flexibility for future expansion. Basement has a dirt floor. Investors will appreciate the ability to lease immediately or reposition/upscale the property. Owner-occupant buyers will find a unique opportunity to live above their business in a prime location. Property has separate gas and electric meters and a single water meter. Parking isn't a problem with 2 car integral garage accessible via Woolslayer Way, or use easily accessible public transportation. This property sits at the center of one of the city's most dynamic growth corridors.