Homes for Sale in 63801

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  /30

  $379,900

  • Land
  • 20 Acres
  • $18,995 per Acre

  37 Plantation Dr, Sandywoods Township, MO 63801

  Discover 20 acres of prime land in one of Sikeston's most sought-after neighborhoods. This rare opportunity offers endless possibilities - whether you're looking to build your dream home with a walk-out basement surrounded by beautiful scenery, or you're a developer ready to design multiple residences in a desirable location. A pond adds natural charm to the landscape, while a lean-to shed

  Mossy Realty Mossy Oak Properties Mozark Realty

  37 Plantation Dr, Sandywoods Township, MO 63801
• 

  

  

  /12

  $124,500

  • 2 Beds
  • 2 Baths
  • 1,152 Sq Ft

  1510 E Kathleen St, Sikeston, MO 63801

  Discover this single-story residence in Sikeston, offering 1,152 square feet of living space on a level 0.25-acre lot. This home features a fresh roof in recent shingling and comes equipped with a dishwasher, refrigerator, washer, and dryer. Inside, you will find a functional layout and a public water/sewer connection. The interior serves as a blank canvas, ready for your custom flooring and

  John David USRealty.com, LLP

  1510 E Kathleen St, Sikeston, MO 63801
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  /38

  $315,000

  • 3 Beds
  • 2 Baths
  • 2,495 Sq Ft

  202 N Brushwick Ave, Sikeston, MO 63801

  Welcome home to this stunning single-level retreat on a huge lot, offering the perfect blend of space, comfort, and style. Step inside to a large open-concept floor plan filled with natural light from dramatic floor-to-ceiling windows, creating an airy, inviting atmosphere ideal for both everyday living and entertaining.The warm and inviting den features beautiful wood paneling, adding

  Lawren McMullan EDGE Realty, ERA Powered

  202 N Brushwick Ave, Sikeston, MO 63801
• 

  

  

  /14

  $199,000

  • 3 Beds
  • 1 Bath
  • 1,296 Sq Ft

  312 Hardin St, Sikeston, MO 63801

  Completely remodeled and ready to move into! Located near the center of Sikeston, close to shopping, schools and banking. The roof is brand new with Owens Corning Duration 30-year shingles, along with LP Smartside on the outside. The kitchen has been competely redone with new cabinets and counter tops. All kitchen appliances are new and come with factory warranty. The wiring, lights, switches,

  Tim Merideth Century 21 Premiere Realty

  312 Hardin St, Sikeston, MO 63801
• 

  

  

  /32

  $149,900

  • 3 Beds
  • 2 Baths
  • 1,250 Sq Ft

  219 Petroleum St, Sikeston, MO 63801

  Take a look at this nice, clean, move-in ready home sporting a NEW ROOF! The charming front porch leads to an open living, kitchen & dining area. Primary bedroom with 3/4 bath, two additional bedrooms, one full bath and a one car attached carport, a 12x24 storage shed with walk-in door and garage door. This is the perfect size for a starter home or someone ready to downsize. Come and see for

  Rebecca Shaver C. Lawrence Realty LLC

  219 Petroleum St, Sikeston, MO 63801
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  /20

  $120,000

  • 2 Beds
  • 1 Bath
  • 1,002 Sq Ft

  2012 Ables Rd, Sikeston, MO 63801

  Welcome to this cozy and inviting 2-bedroom, 1-bath home in Sikeston. It features a comfortable layout with a bright living spaced and functional kitchen. The attached carport adds convenience, while the spacious backyard offers plenty of room to relax, entertain, or enjoy the outdoors.

  Ashlyn Sutton Century 21 Premiere Realty

  2012 Ables Rd, Sikeston, MO 63801
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  /34

  $210,000

  • 4 Beds
  • 2 Baths
  • 1,922 Sq Ft

  406 Lynn St, Sikeston, MO 63801

  Located in the highly sought-after Mini Farms subdivision just outside Sikeston, this beautifully remodeled 4-bedroom, 2-bath home on 1.84 acres offers the perfect combination of modern updates and country-style living with convenient access to town. The home was completely remodeled in 2025 and includes major system updates such as new gas heat and air, a new gas tankless water heater, and an

  Lynsey Perry Silverthorn Realty, LLC

  406 Lynn St, Sikeston, MO 63801
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  /36

  $250,000

  • 3 Beds
  • 3 Baths
  • 1,492 Sq Ft

  119 Depro Ave, Sikeston, MO 63801

  Newly remodeled and move-in ready just outside Sikeston! Sitting on a spacious corner lot with 0.7187 acres, this home gives you room to breathe and room to work. You’ll love the outdoor setup with a large shed plus a brand-new 30x40 pole barn, perfect for hobbies, storage, or a workshop. New roof, fresh updates, and space inside and out—this one checks all the boxes!

  Jessica Moore EXP Realty, LLC

  119 Depro Ave, Sikeston, MO 63801
• 

  

  /19

  $184,900

  • 4 Beds
  • 2 Baths
  • 1,914 Sq Ft

  410 Hux St, Sikeston, MO 63801

  Discover your dream home in this delightful 4-bedroom, 2-bath ranch that perfectly blends comfort and style. Nestled on a serene street, this inviting residence features a spacious front porch, ideal for sipping morning coffee or enjoying evening sunsets. Step inside to find a bright and airy layout that welcomes you with warmth and charm.The heart of the home boasts an open living area,

  Brandon Kielhofner EPM Real Estate

  410 Hux St, Sikeston, MO 63801
• 

  

  /14

  $119,000

  • 3 Beds
  • 1 Bath
  • 1,080 Sq Ft

  318 Kendall St, Sikeston, MO 63801

  Welcome home to this fully remodeled 3-bedroom, 1-bath charmer, offering modern comfort and timeless style. Every detail has been thoughtfully updated, including fresh flooring, contemporary fixtures, new paint, and an inviting open layout that maximizes both light and space. All three bedrooms are generously sized, providing flexibility for family, guests, or a home office. The updated bathroom

  Lawren McMullan EDGE Realty, ERA Powered

  318 Kendall St, Sikeston, MO 63801
• 

  

  /11

  $127,500

  • 2 Beds
  • 1 Bath
  • 910 Sq Ft

  628 Moore Ave, Sikeston, MO 63801

  This charming bungalow in Sikeston's historic district has been beautifully updated and is ready for its new owner. Featuring 2 bedrooms and 1 bath, it's the perfect home for first-time buyers or anyone looking to downsize. Conveniently located withing walking distance to the YMCA and local grocery stores, this home offers both everyday convenience and timeless charm.

  Rene Church Century 21 Premiere Realty

  628 Moore Ave, Sikeston, MO 63801
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  /9

  $106,000

  • Land
  • 0.86 Acre
  • $123,256 per Acre

  190 Cypress Branch Rd, Sikeston, MO 63801

  Greenfield North will be a gated, fenced cul-de-sac community located inside the city limits of Sikeston, just off Highway 61. You'll experience the convenience of town combined with the calm of a quiet neighborhood. Enjoy a private secure location for your custom home. The covenants and restrictions were designed to help preserve property values and maintain a safe, high-quality, and comfortable

  Tim Merideth Century 21 Premiere Realty

  190 Cypress Branch Rd, Sikeston, MO 63801
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  /2

  $15,000

  • Land
  • 0.2 Acre
  • $75,000 per Acre

  807 Bollweevil Blvd, Sikeston, MO 63801

  This vacant residential lot is ready for you to build on, and priced to help you get started quickly. Covenants and restrictions are in place to help protect your investment. Located inside Sikeston City Limits. Additional Rooms: In Platted Subdv.

  Tim Merideth Century 21 Premiere Realty

  807 Bollweevil Blvd, Sikeston, MO 63801
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  /3

  $42,500

  • Land
  • 0.3 Acre
  • $141,667 per Acre

  404 Aster, Sikeston, MO 63801

  Welcome to Saddleridge South, 2nd Addition! Located inside the city limits of Sikeston, these lots have utilities already ran to them and are ready for construction to begin. You can be the general contractor, or we can introduce you to some of the area's finest builders to work with. Covenants and restrictions were crafted to help protect property value and are available upon request. These are

  Tim Merideth Century 21 Premiere Realty

  404 Aster, Sikeston, MO 63801
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  /2

  $79,900

  • 3 Beds
  • 2 Baths
  • 1,232 Sq Ft

  338 E Gladys St, Sikeston, MO 63801

  Great opportunity for investors! This 3-bedroom property offers solid potential as a rental or flip, with a manageable layout and room to add value. Whether you're expanding your portfolio or getting started in real estate, this is a smart, affordable option.

  Christina Essner EXP Realty, LLC

  338 E Gladys St, Sikeston, MO 63801
• 

  /2

  $54,900

  • 2 Beds
  • 1 Bath
  • 600 Sq Ft

  627 Vernon Ave, Sikeston, MO 63801

  Great opportunity for investors! This 2-bedroom property offers solid potential as a rental or flip, with a manageable layout and room to add value. Whether you're expanding your portfolio or getting started in real estate, this is a smart, affordable option.

  Christina Essner EXP Realty, LLC

  627 Vernon Ave, Sikeston, MO 63801
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  /3

  $42,500

  • Land
  • 0.28 Acre
  • $151,786 per Acre

  416 Secretariat, Sikeston, MO 63801

  Welcome to Saddleridge South, 2nd Addition! Located inside the city limits of Sikeston, these lots have utilities already ran to them and are ready for construction to begin. You can be the general contractor, or we can introduce you to some of the area's finest builders to work with. Covenants and restrictions were crafted to help protect property value and are available upon request. These are

  Tim Merideth Century 21 Premiere Realty

  416 Secretariat, Sikeston, MO 63801
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  /8

  $90,000

  • Land
  • 3 Acres
  • $30,000 per Acre

  2215 State Highway U, Sikeston, MO 63801

  Imagine a quiet country setting just a short drive to Interstate 55 with only 15 minutes to both Cape Girardeau & Sikeston. This property is not only located in Kelly School district but situated directly on a paved state road with access to county water. This cleared lot is ready for you to build your dream home on with a lot of space to stretch out and enjoy a peaceful country setting.

  Kyla Evans Paul Kitchen & Associates

  2215 State Highway U, Sikeston, MO 63801
• 

  

  /3

  $42,500

  • Land
  • 0.27 Acre
  • $157,407 per Acre

  405 Aster, Sikeston, MO 63801

  Welcome to Saddleridge South, 2nd Addition! Located inside the city limits of Sikeston, these lots have utilities already ran to them and are ready for construction to begin. You can be the general contractor, or we can introduce you to some of the area's finest builders to work with. Covenants and restrictions were crafted to help protect property value and are available upon request. These are

  Tim Merideth Century 21 Premiere Realty

  405 Aster, Sikeston, MO 63801
• 

  

  /21

  $1,000,000

  • 1,800 Sq Ft

  361 County Highway 405, Sikeston, MO 63801

  Exceptional Poultry Farm Opportunity with a 1,800 sqft 3 bed 2 bath home that was built in 2020. Presenting a rare opportunity to acquire a modern, income-producing poultry operation. This farm has been meticulously maintained and is available due to the owners’ retirement. Designed with efficiency and productivity in mind, the property offers state-of-the-art facilities and equipment to support

  Christy Lawrence C. Lawrence Realty LLC

  361 County Highway 405, Sikeston, MO 63801
• 

  

  /3

  $42,500

  • Land
  • 0.39 Acre
  • $108,974 per Acre

  407 Aster, Sikeston, MO 63801

  Welcome to Saddleridge South, 2nd Addition! Located inside the city limits of Sikeston, these lots have utilities already ran to them and are ready for construction to begin. You can be the general contractor, or we can introduce you to some of the area's finest builders to work with. Covenants and restrictions were crafted to help protect property value and are available upon request. These are

  Tim Merideth Century 21 Premiere Realty

  407 Aster, Sikeston, MO 63801
• 

  

  /3

  $42,500

  • Land
  • 0.39 Acre
  • $108,974 per Acre

  308 Citation Dr, Sikeston, MO 63801

  Come see Sikeston's newest subdivision! These are excellent sites for first-time home buyers, families, or those wanting to downsize. Turn south off Broadway onto South Illinois Avenue to two new cul-de-sacs, ensuring reduced traffic. This subdivision is inside Sikeston City limits, and has covenants and restrictions to help protect your investment. Super easy, fast access to Highway 60 and

  Tim Merideth Century 21 Premiere Realty

  308 Citation Dr, Sikeston, MO 63801
• 

  /2

  $15,000

  • Land
  • 0.28 Acre
  • $53,571 per Acre

  801 Bollweevil Blvd, Sikeston, MO 63801

  This vacant residential lot is ready for you to build on, and priced to help you get started quickly. Covenants and restrictions are in place to help protect your investment. Located inside Sikeston City Limits. Additional Rooms: In Platted Subdv.

  Tim Merideth Century 21 Premiere Realty

  801 Bollweevil Blvd, Sikeston, MO 63801
• 

  

  /3

  $42,500

  • Land
  • 0.4 Acre
  • $106,250 per Acre

  402 Secretariat, Sikeston, MO 63801

  Welcome to Saddleridge South, 2nd Addition! Located inside the city limits of Sikeston, these lots have utilities already ran to them and are ready for construction to begin. You can be the general contractor, or we can introduce you to some of the area's finest builders to work with. Covenants and restrictions were crafted to help protect property value and are available upon request. These are

  Tim Merideth Century 21 Premiere Realty

  402 Secretariat, Sikeston, MO 63801
• 

  /2

  $15,000

  • Land
  • 0.21 Acre
  • $71,429 per Acre

  811 Cotton Ridge Dr, Sikeston, MO 63801

  This vacant residential lot is ready for you to build on, and priced to help you get started quickly. Covenants and restrictions are in place to help protect your investment. Located inside Sikeston City Limits. Additional Rooms: In Platted Subdv.

  Tim Merideth Century 21 Premiere Realty

  811 Cotton Ridge Dr, Sikeston, MO 63801
• 

  /2

  $15,000

  • Land
  • 0.2 Acre
  • $75,000 per Acre

  811 Bollweevil Blvd, Sikeston, MO 63801

  This vacant residential lot is ready for you to build on, and priced to help you get started quickly. Covenants and restrictions are in place to help protect your investment. Located inside Sikeston City Limits. Additional Rooms: In Platted Subdv.

  Tim Merideth Century 21 Premiere Realty

  811 Bollweevil Blvd, Sikeston, MO 63801
• 

  

  /7

  $199,000

  • Land
  • 2 Acres
  • $99,500 per Acre

  224 S Interstate Dr, Miner, MO 63801

  This 2 acre commercial lot is ready for you to build to suit your needs.

  Thomas Williams Century 21 Premiere Realty

  224 S Interstate Dr, Miner, MO 63801
• 

  

  /9

  $108,000

  • Land
  • 0.79 Acre
  • $136,709 per Acre

  170 Cypress Branch Rd, Sikeston, MO 63801

  Greenfield North will be a gated, fenced cul-de-sac community located inside the city limits of Sikeston, just off Highway 61. You'll experience the convenience of town combined with the calm of a quiet neighborhood. Enjoy a private secure location for your custom home. The covenants and restrictions were designed to help preserve property values and maintain a safe, high-quality, and comfortable

  Tim Merideth Century 21 Premiere Realty

  170 Cypress Branch Rd, Sikeston, MO 63801
• 

  /2

  $54,900

  • 2 Beds
  • 1 Bath
  • 736 Sq Ft

  319 Benton St, Sikeston, MO 63801

  Great opportunity for investors! This 2-bedroom property offers solid potential as a rental or flip, with a manageable layout and room to add value. Whether you're expanding your portfolio or getting started in real estate, this is a smart, affordable option.

  Christina Essner EXP Realty, LLC

  319 Benton St, Sikeston, MO 63801
• 

  

  /3

  $42,500

  • Land
  • 0.39 Acre
  • $108,974 per Acre

  418 Secretariat, Sikeston, MO 63801

  Welcome to Saddleridge South, 2nd Addition! Located inside the city limits of Sikeston, these lots have utilities already ran to them and are ready for construction to begin. You can be the general contractor, or we can introduce you to some of the area's finest builders to work with. Covenants and restrictions were crafted to help protect property value and are available upon request. These are

  Tim Merideth Century 21 Premiere Realty

  418 Secretariat, Sikeston, MO 63801
• 

  /2

  $69,900

  • 2 Beds
  • 1 Bath
  • 837 Sq Ft

  322 Helen St, Sikeston, MO 63801

  Great opportunity for investors! This 2-bedroom property offers solid potential as a rental or flip, with a manageable layout and room to add value. Whether you're expanding your portfolio or getting started in real estate, this is a smart, affordable option.

  Christina Essner EXP Realty, LLC

  322 Helen St, Sikeston, MO 63801
• 

  /2

  $15,000

  • Land
  • 0.28 Acre
  • $53,571 per Acre

  800 Cotton Ridge Dr, Sikeston, MO 63801

  This vacant residential lot is ready for you to build on, and priced to help you get started quickly. Covenants and restrictions are in place to help protect your investment. Located inside Sikeston City Limits. Additional Rooms: In Platted Subdv.

  Tim Merideth Century 21 Premiere Realty

  800 Cotton Ridge Dr, Sikeston, MO 63801
• 

  /2

  $44,000

  • 3 Beds
  • 2 Baths
  • 1,124 Sq Ft

  108 Adams St, Sikeston, MO 63801

  If you are looking for an investment property or a home that requires some TLC, this home is ready for your renovations. Priced to sell quickly, schedule your viewing today!

  Thomas Williams Century 21 Premiere Realty

  108 Adams St, Sikeston, MO 63801
• 

  

  /4

  $39,000

  • Land
  • 1.67 Acres
  • $23,353 per Acre

  38 Matt St, Sikeston, MO 63801

  Lauren DeWitt EDGE Realty, ERA Powered

  38 Matt St, Sikeston, MO 63801
• 

  

  /4

  $500,000

  1201 Lawrence St, Sikeston, MO 63801

  1.24 acres of commercial land located on the corner of Stallcup Drive and Lawrence Street. This lot is located beside a 60 unit apartment complex; and there is a Lowe's, JC Penney and Taco Bell within walking distance. Concrete streets. Located in New Madrid County, Sikeston city limits. Zoned light industrial.

  Tim Merideth Century 21 Premiere Realty

  1201 Lawrence St, Sikeston, MO 63801
• 

  

  /3

  $42,500

  • Land
  • 0.41 Acre
  • $103,659 per Acre

  304 Seabiscuit Dr, Sikeston, MO 63801

  Come see Sikeston's newest subdivision! These are excellent sites for first-time home buyers, families, or those wanting to downsize. Turn south off Broadway onto South Illinois Avenue to two new cul-de-sacs, ensuring reduced traffic. This subdivision is inside Sikeston City limits, and has covenants and restrictions to help protect your investment. Super easy, fast access to Highway 60 and

  Tim Merideth Century 21 Premiere Realty

  304 Seabiscuit Dr, Sikeston, MO 63801
• 

  

  /9

  $108,000

  • Land
  • 0.81 Acre
  • $133,333 per Acre

  140 Cypress Branch Rd, Sikeston, MO 63801

  Greenfield North will be a gated, fenced cul-de-sac community located inside the city limits of Sikeston. Just off Highway 61. You'll experience the convenience of town combined with the calm of a quiet neighborhood. Enjoy a private, secure location for your custom home. The covenants and restrictions were designed to help preserve property values and maintain a safe, high-quality, and

  Tim Merideth Century 21 Premiere Realty

  140 Cypress Branch Rd, Sikeston, MO 63801
• 

  

  /11

  $99,900

  • 3 Beds
  • 1 Bath
  • 1,237 Sq Ft

  303 Greer Ave, Sikeston, MO 63801

  Are you ready for a small home in Sikeston? You can sit on the covered, front porch and enjoy a morning cup of coffee while watching others out and about! This Bungalow-style home boasts of 3 bedrooms, 1 bathroom, an eat-in kitchen, a covered carport in back yard all located on a corner lot. The kitchen has several cabinets, an island along the wall, and a range and a dishwasher included. It's

  Scott Harrison Delta Realty, LLC

  303 Greer Ave, Sikeston, MO 63801
• 

  

  /12

  $195,000

  • 3 Beds
  • 2 Baths
  • 1,421 Sq Ft

  112 N 6th St, Sikeston, MO 63801

  Step inside to find a bright and airy living space featuring a freshly painted interior and brand-new flooring throughout. The heart of the home is the spacious, open-concept kitchen—perfect for entertaining—boasting ample cabinetry and a layout that flows seamlessly into the dining and living areas. Both bathrooms have been updated, ensuring this home is move-in ready from day one.Situated

  Kaci Self Epique Realty

  112 N 6th St, Sikeston, MO 63801
• 

  

  /4

  $500,000

  1209 Lawrence St, Sikeston, MO 63801

  Commercial land on a corner lot available for development in Sikeston's busiest retail area. 1.05 acres zoned light industrial is located directly across the street from Wal-Mart. Other major retailers located close by include JC Penney, Goodies, and Lowe's. Located in New Madrid county, Sikeston city limits.

  Tim Merideth Century 21 Premiere Realty

  1209 Lawrence St, Sikeston, MO 63801

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