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Homes for Sale in 63801

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    $500,000

    1209 Lawrence St, Sikeston, MO 63801

    Commercial land on a corner lot available for development in Sikeston's busiest retail area. 1.05 acres zoned light industrial is located directly across the street from Wal-Mart. Other major retailers located close by include JC Penney, Goodies, and Lowe's. Located in New Madrid county, Sikeston city limits.

    Tim Merideth Century 21 Premiere Realty

    1209 Lawrence St, Sikeston, MO 63801
  • /2

    $48,000

    • 2 Beds
    • 1 Bath
    • 1,335 Sq Ft

    420 Malcolm Ave, Sikeston, MO 63801

    If you are looking for an investment property or a home that requires some TLC, this home is ready for your renovations. Priced to sell quickly, schedule your viewing today!

    Thomas Williams Century 21 Premiere Realty

    420 Malcolm Ave, Sikeston, MO 63801
  • /38

    $344,500

    • 3 Beds
    • 3 Baths
    • 6,536 Sq Ft

    901 Moore Ave, Sikeston, MO 63801

    Do you like both indoor and outdoor space? This is the one for you. This home includes a large sunroom with ceiling fans located on the back of the house overlooking gorgeous landscaping. There's also outdoor space on the composite deck if you'd like a little sun. This nice brick home is on a corner lot in Sikeston's north end. Inside, the kitchen was recently remodeled with a nice island and

    Tim Merideth Century 21 Premiere Realty

    901 Moore Ave, Sikeston, MO 63801
  • /3

    $42,500

    • Land
    • 0.34 Acre
    • $125,000 per Acre

    404 Secretariat, Sikeston, MO 63801

    Welcome to Saddleridge South, 2nd Addition! Located inside the city limits of Sikeston, these lots have utilities already ran to them and are ready for construction to begin. You can be the general contractor, or we can introduce you to some of the area's finest builders to work with. Covenants and restrictions were crafted to help protect property value and are available upon request. These are

    Tim Merideth Century 21 Premiere Realty

    404 Secretariat, Sikeston, MO 63801
  • /13

    $171,000

    • Land
    • 19 Acres
    • $9,000 per Acre

    000 Heathercrest St, Rootwad Township, MO 63801

    19 +/- acres of row-crop farmland with development potential located just outside Sikeston, Missouri. Property includes approximately 19 acres of tillable cropland plus 9 platted building lots. Ideal for farmland investors, developers, or buyers seeking agricultural income, residential development, or long-term land investment. Level, open ground with easy access to Sikeston, highways, and local

    Geoffrey Myers Living The Dream Inc.

    000 Heathercrest St, Rootwad Township, MO 63801
  • /4

    $195,000

    • Land
    • 0.72 Acre
    • $270,833 per Acre

    116 Hospitality Dr, Sikeston, MO 63801

    Vacant, level lot. Not in the flood plain.

    Larry Lindsey Century 21 Premiere Realty

    116 Hospitality Dr, Sikeston, MO 63801
  • /2

    $15,000

    • Land
    • 0.24 Acre
    • $62,500 per Acre

    810 Cotton Ridge Dr, Sikeston, MO 63801

    This vacant residential lot is ready for you to build on, and priced to help you get started quickly. Covenants and restrictions are in place to help protect your investment. Located inside Sikeston City Limits. Additional Rooms: In Platted Subdv.

    Tim Merideth Century 21 Premiere Realty

    810 Cotton Ridge Dr, Sikeston, MO 63801
  • /10

    $74,500

    • 2 Beds
    • 1 Bath
    • 884 Sq Ft

    516 Coleman St, Sikeston, MO 63801

    Welcome to 516 Coleman St. in Sikeston, a 2-bedroom home that combines classic charm with modern updates. Step inside to find some original hardwood floors that add warmth and character, complemented by new carpet in the bedrooms for a cozy touch. The fully remodeled bathroom features stylish finishes and a fresh, contemporary feel. This home offers comfortable living spaces, great natural light,

    Lauren DeWitt EDGE Realty, ERA Powered

    516 Coleman St, Sikeston, MO 63801
  • /21

    $265,000

    • 3 Beds
    • 2.5 Baths
    • 1,774 Sq Ft

    1811 State Highway Z, Sikeston, MO 63801

    This 3 bedroom, 2.5 bath home offers the perfect blend of space, privacy, and convenience. Situated on just over an acre +/- outside of city limits, you can enjoy peaceful country living while still being less than a 10 minute drive to town. The spacious layout provides comfortable living with thoughtful updates throughout. A standout feature is the shop, which offers over a thousand square feet

    Rachel Sitzes Poplar Bluff Realty Inc

    1811 State Highway Z, Sikeston, MO 63801
  • /22

    $225,000 Open Sun 1PM - 3PM

    • 3 Beds
    • 2 Baths
    • 1,674 Sq Ft

    707 Bayberry Dr, Sikeston, MO 63801

    Welcome home to this well-maintained 3-bedroom, 2-bath split-level home nestled in a quiet subdivision. Featuring an oversized master bedroom, a functional split-level layout, and a basement offering additional living or storage space, this home provides both comfort and flexibility. The attached garage adds convenience, while the location truly shines—situated within walking distance to the

    Lynsey Perry Silverthorn Realty, LLC

    707 Bayberry Dr, Sikeston, MO 63801
  • /14

    $94,400

    • 2 Beds
    • 1 Bath
    • 1,000 Sq Ft

    406 W Gladys St, Sikeston, MO 63801

    Step inside this beautifully remodeled 2-bedroom, 1-bath home that’s move-in ready and full of modern updates! Fresh interior and exterior paint give the home a crisp, inviting look, while the brand-new flooring throughout adds warmth and style. Outside, the freshly painted exterior provides excellent curb appeal, and the manageable yard makes maintenance a breeze. Whether you’re a first-time

    Lawren McMullan EDGE Realty, ERA Powered

    406 W Gladys St, Sikeston, MO 63801
  • /2

    $90,000

    • 3 Beds
    • 1 Bath
    • 1,077 Sq Ft

    849 William St, Sikeston, MO 63801

    Enjoy entertaining in this 3-bedroom, 1-bath home with a spacious yard and separate dining room. Updates like the new dryer plug-in, baseboard heaters, fresh interior paint, kitchen cabinets, and sink add modern convenience while keeping maintenance low. Plus, the covered carport provides protected parking. Set up a showing today!

    Tasha Cardin EXP Realty, LLC

    849 William St, Sikeston, MO 63801
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    $299,900

    • 3 Beds
    • 2 Baths
    • 1,734 Sq Ft

    1205 Yosemite, Sikeston, MO 63801

    This well-maintained 3-bedroom, 2-bath home offers a thoughtful layout designed for everyday comfort and convenience, complemented by a modern, neutral color palette throughout. The laundry room is conveniently located just off the garage, making daily routines a breeze. The kitchen features granite countertops and stainless steel appliances, blending style with functionality. The primary suite

    Lynsey Perry Silverthorn Realty, LLC

    1205 Yosemite, Sikeston, MO 63801
  • /3

    $42,500

    • Land
    • 0.39 Acre
    • $108,974 per Acre

    419 Secretariat, Sikeston, MO 63801

    Welcome to Saddleridge South, 2nd Addition! Located inside the city limits of Sikeston, these lots have utilities already ran to them and are ready for construction to begin. You can be the general contractor, or we can introduce you to some of the area's finest builders to work with. Covenants and restrictions were crafted to help protect property value and are available upon request. These are

    Tim Merideth Century 21 Premiere Realty

    419 Secretariat, Sikeston, MO 63801
  • /2

    $47,000

    • 4 Beds
    • 2 Baths
    • 1,300 Sq Ft

    408 Carroll St, Sikeston, MO 63801

    If you are looking for an investment property or a home that requires some TLC, this home is ready for your renovations. Priced to sell quickly, schedule your viewing today!

    Thomas Williams Century 21 Premiere Realty

    408 Carroll St, Sikeston, MO 63801
  • /14

    $3,960,000

    0 Ables Rd, Sikeston, MO 63801

    Located on the northwest corner of I-55 and I-57 inside Sikeston City limits, this ground is in a prime location for commercial development. This property can be accessed via Ables Road or County Line Road. Owner will subdivide into smaller tracts. There is power, water and sewer available, all provided by Sikeston Board of Municipal Utilities.

    Tim Merideth Century 21 Premiere Realty

    0 Ables Rd, Sikeston, MO 63801
  • /2

    $69,900

    • 2 Beds
    • 1 Bath
    • 1,204 Sq Ft

    334 E Kathleen St, Sikeston, MO 63801

    Christina Essner EXP Realty, LLC

    334 E Kathleen St, Sikeston, MO 63801
  • /2

    $106,000

    • Land
    • 0.86 Acre
    • $123,256 per Acre

    120 Cypress Branch Rd, Sikeston, MO 63801

    Greenfield North will be a gated, fenced cul-de-sac community located inside the city limits of Sikeston, just off Highway 61. You'll experience the convenience of town combined with the calm of a quiet neighborhood. Enjoy a private, secure location for your custom home. The covenants and restrictions were designed to help preserve property values and maintain a safe, high-quality, and

    Tim Merideth Century 21 Premiere Realty

    120 Cypress Branch Rd, Sikeston, MO 63801
  • /3

    $42,500

    • Land
    • 0.35 Acre
    • $121,429 per Acre

    408 Secretariat, Sikeston, MO 63801

    Welcome to Saddleridge South, 2nd Addition! Located inside the city limits of Sikeston, these lots have utilities already ran to them and are ready for construction to begin. You can be the general contractor, or we can introduce you to some of the area's finest builders to work with. Covenants and restrictions were crafted to help protect property value and are available upon request. These are

    Tim Merideth Century 21 Premiere Realty

    408 Secretariat, Sikeston, MO 63801
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    $259,900

    • 3 Beds
    • 1.5 Baths
    • 1,782 Sq Ft

    109 Lynn St, Sikeston, MO 63801

    Welcome to 109 Lynn St. in Sikeston, located in the desirable Mini Farms subdivision - where space and comfort come together for family living. This 3-bedroom, 2-bathroom home offers two spacious living rooms, perfect for family movie nights, play areas, or hosting friends and relatives. Sitting on 1.62 acres, there is plenty of room for kids to play, pets to roam, and outdoor gatherings to

    Lauren DeWitt EDGE Realty, ERA Powered

    109 Lynn St, Sikeston, MO 63801
  • /3

    $42,500

    • Land
    • 0.33 Acre
    • $128,788 per Acre

    403 Secretariat, Sikeston, MO 63801

    Welcome to Saddleridge South, 2nd Addition! Located inside the city limits of Sikeston, these lots have utilities already ran to them and are ready for construction to begin. You can be the general contractor, or we can introduce you to some of the area's finest builders to work with. Covenants and restrictions were crafted to help protect property value and are available upon request. These are

    Tim Merideth Century 21 Premiere Realty

    403 Secretariat, Sikeston, MO 63801
  • /2

    $8,500

    • Land
    • 0.17 Acre
    • $51,082 per Acre

    Lot 6 Fisher Dr, Morehouse, MO 63868

    Nice corner lot located at the intersection of Fisher Drive and Spruce Street in Morehouse, Missouri. This level lot offers excellent access and visibility and would make a great home site or investment property. City utilities are available nearby (buyer to verify). Convenient location within a quiet residential area, just a short drive to Sikeston and area amenities.

    Stephanie Anderson SMG Realty

    Lot 6 Fisher Dr, Morehouse, MO 63868
  • /2

    $108,000

    • Land
    • 0.99 Acre
    • $109,091 per Acre

    110 Cypress Branch Rd, Sikeston, MO 63801

    Greenfield North will be a gated, fenced cul-de-sac community located inside the city limits of Sikeston, just off Highway 61. You'll experience the convenience of town combined with the calm of a quiet neighborhood. Enjoy a private, secure location for your custom home. The covenants and restrictions were designed to help preserve property values and maintain safe, high-quality, and comfortable

    Tim Merideth Century 21 Premiere Realty

    110 Cypress Branch Rd, Sikeston, MO 63801
  • /2

    $69,900

    • 2 Beds
    • 2 Baths
    • 1,008 Sq Ft

    118 N 3rd St, Sikeston, MO 63801

    Welcome to this 2-bedroom, 2-bath ranch home—a perfect choice for a starter home or someone looking to downsize! Enjoy the ease of single-level living with a functional layout and plenty of natural light throughout. The home includes a detached garage, offering extra storage or workspace potential. With its classic design and solid bones, this property is full of potential to make it your own.

    Christina Essner EXP Realty, LLC

    118 N 3rd St, Sikeston, MO 63801
  • /2

    $47,000

    • 3 Beds
    • 1 Bath
    • 1,309 Sq Ft

    1140 Ruth St, Sikeston, MO 63801

    If you are looking for an investment property or a home that requires some TLC, this home is ready for your renovations. Priced to sell quickly, schedule your viewing today!

    Thomas Williams Century 21 Premiere Realty

    1140 Ruth St, Sikeston, MO 63801
  • /2

    $15,000

    • Land
    • 0.2 Acre
    • $75,000 per Acre

    809 Bollweevil Blvd, Sikeston, MO 63801

    This vacant residential lot is ready for you to build on, and priced to help you get started quickly. Covenants and restrictions are in place to help protect your investment. Located inside Sikeston City Limits. Additional Rooms: In Platted Subdv.

    Tim Merideth Century 21 Premiere Realty

    809 Bollweevil Blvd, Sikeston, MO 63801
  • /7

    $169,900

    • 3 Beds
    • 1.5 Baths
    • 1,653 Sq Ft

    926 Crescent Dr, Sikeston, MO 63801

    This beautifully maintained all-brick hoe is nestled in a quiet, family-friendly neighborhood. It features 3 bedrooms, 1.5 baths, and a full basement with the potential for an additional bathroom. The interior boasts new laminate flooring throughout, and the roof was replaced in 2020, and the HVAC is 2 years old. Enjoy a spacious kitchen, with a double oven - perfect for cooking and entertaining

    Rene Church Century 21 Premiere Realty

    926 Crescent Dr, Sikeston, MO 63801
  • /2

    $59,900

    • 2 Beds
    • 1 Bath
    • 744 Sq Ft

    321 Benton St, Sikeston, MO 63801

    Investor Opportunity! This income-producing property offers solid potential with hardwood and tile floors throughout, combining durability with low-maintenance appeal. The fenced-in yard adds value for tenants seeking outdoor space, and the property's layout and location make it an attractive rental option. Whether you're expanding your portfolio or diving into your first investment, this is a

    Christina Essner EXP Realty, LLC

    321 Benton St, Sikeston, MO 63801
  • /16

    $188,900

    • 3 Beds
    • 2 Baths
    • 1,985 Sq Ft

    719 N West St, Sikeston, MO 63801

    Nice brick home with a family room added on the back. Wood burning fireplace. Huge walk in pantry. The bedrooms area ll good size. Master bath, unfinished basement perfect for storage. Seller offers a concession of $3,000 for buyers closing costs or for updates.

    Ricki Ing Century 21 Ashland Realty

    719 N West St, Sikeston, MO 63801
  • /15

    $250,999 Open Sun 1PM - 3PM

    • 3 Beds
    • 1.5 Baths
    • 2,034 Sq Ft

    106 Holmes Dr, Sikeston, MO 63801

    Spacious, modern, updated, extremely well appointed. Enter into a large living room plus a cozy family room at the back. Lots of natural light thru out. large eat in kitchen with island, all kitchen appliances stay including convection/air fryer oven and 2 pantry cabinets.. Vinyl plank flooring with new carpet in two bedrooms. Electric insert in the wood fireplace, the owner has never burned wood

    Linda Essner Century 21 Ashland Realty

    106 Holmes Dr, Sikeston, MO 63801
  • /2

    $48,000

    • 3 Beds
    • 2 Baths
    • 1,120 Sq Ft

    1205 W Murray Ln, Sikeston, MO 63801

    If you are looking for an investment property or a home that requires some TLC, this home is ready for your renovations. Priced to sell quickly, schedule your viewing today!

    Thomas Williams Century 21 Premiere Realty

    1205 W Murray Ln, Sikeston, MO 63801
  • /2

    $72,500

    • 2 Beds
    • 1 Bath
    • 1,049 Sq Ft

    733 Matthews Ave, Sikeston, MO 63801

    Are you a first time homebuyer or looking to expand your investment portfolio? This cozy 2 bedroom home might be just for you! This home is located in a quiet neighborhood, yet is conveniently located close to shopping centers, schools, and both mid-town and downtown. This home offers an eat-in kitchen, laundry room and full bathroom with tub all that have been newly updated. This home is great

    Katrina Dowell C. Lawrence Realty LLC

    733 Matthews Ave, Sikeston, MO 63801
  • /37

    $279,999

    • 5 Beds
    • 3 Baths
    • 2,800 Sq Ft

    216 Sherrie Dr, Sikeston, MO 63801

    Gracefully designed with comfort and charm in mind, this 4-bedroom, 3-bath home, just outside the city limits, offers the perfect blend of space, style, and Southern warmth. The open-concept layout flows effortlessly through the expansive family, dining, and kitchen areas—ideal for gathering, entertaining, and everyday living. The kitchen features soft-close cabinetry, quartz countertops, and

    Lynsey Perry Silverthorn Realty, LLC

    216 Sherrie Dr, Sikeston, MO 63801
  • /2

    $74,900

    • 3 Beds
    • 1 Bath
    • 1,252 Sq Ft

    512 S New Madrid St, Sikeston, MO 63801

    Great opportunity for investors! This 3-bedroom property offers solid potential as a rental or flip, with a manageable layout and room to add value. Whether you're expanding your portfolio or getting started in real estate, this is a smart, affordable option. Don't miss out on this income-producing opportunity—schedule a showing today to see the possibilities!

    Christina Essner EXP Realty, LLC

    512 S New Madrid St, Sikeston, MO 63801
  • /3

    $42,500

    • Land
    • 0.46 Acre
    • $92,391 per Acre

    311 Citation Dr, Sikeston, MO 63801

    Come see Sikeston's newest subdivision! These are excellent sites for first-time home buyers, families, or those wanting to downsize. Turn south off Broadway onto South Illinois Avenue to two new cul-de-sacs, ensuring reduced traffic. This subdivision is inside Sikeston City limits, and has covenants and restrictions to help protect your investment. Super easy, fast access to Highway 60 and

    Tim Merideth Century 21 Premiere Realty

    311 Citation Dr, Sikeston, MO 63801
  • /12

    $264,000

    • 3 Beds
    • 2 Baths
    • 1,965 Sq Ft

    402 Garner St, Sikeston, MO 63801

    FIRST TIME ON THE MARKET !CUSTOM BUILT, ONE OWNER HOME, OPEN FLOOR PLAN WITH CUSTOM CABINETS, FLOORING , HUGE WALK IN SHOWER, INCLOSED SUNROOM ,ALL SITTING ON A LARGE CORNER LOT IN THE WESTVIEW SUBDIVISION AND SIKESTON SCHOOL DISTRICT .

    Tony McDonald McDonald Realty

    402 Garner St, Sikeston, MO 63801
  • /2

    $15,000

    • Land
    • 0.24 Acre
    • $62,500 per Acre

    804 Cotton Ridge Dr, Sikeston, MO 63801

    This vacant residential lot is ready for you to build on, and priced to help you get started quickly. Covenants and restrictions are in place to help protect your investment. Located inside Sikeston City Limits. Additional Rooms: In Platted Subdv.

    Tim Merideth Century 21 Premiere Realty

    804 Cotton Ridge Dr, Sikeston, MO 63801
  • /4

    $184,000

    0 County Hwy 544 Unit MAR25013765, Sikeston, MO

    Nice small farm Interstate 55 and Interstate 57 agricultural and commercial property. Farm has been graded and is irrigated by neighbors well. Has County Road blacktop frontage.

    Jeff Carter

    0 County Hwy 544 Unit MAR25013765, Sikeston, MO
  • /2

    $44,900

    • 2 Beds
    • 1.5 Baths
    • 576 Sq Ft

    136 N 6th St, Sikeston, MO 63801

    Great opportunity for investors! This 2-bedroom property offers solid potential as a rental or flip, with a manageable layout and room to add value. Whether you're expanding your portfolio or getting started in real estate, this is a smart, affordable option.

    Christina Essner EXP Realty, LLC

    136 N 6th St, Sikeston, MO 63801
  • /34

    $200,000

    • 3 Beds
    • 2 Baths
    • 1,750 Sq Ft

    918 Hawthorn Dr, Sikeston, MO 63801

    Back on the Market- No Fault to Sellers! Beautiful and charming move-in ready ranch home! This thoughtfully updated property features a great floor plan with an open kitchen flowing into the dining room, 3 bedrooms on the main level, and a very spacious master bathroom. Step inside to a brand-new kitchen (2025) with modern finishes and some new appliances. Major updates include new HVAC,

    Christina Essner EXP Realty, LLC

    918 Hawthorn Dr, Sikeston, MO 63801

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