Sikeston, MO Homes for Sale with Acreage

Located in the highly sought-after Mini Farms subdivision just outside Sikeston, this beautifully remodeled 4-bedroom, 2-bath home on 1.84 acres offers the perfect combination of modern updates and country-style living with convenient access to town. The home was completely remodeled in 2025 and includes major system updates such as new gas heat and air, a new gas tankless water heater, and an

Lynsey Perry Silverthorn Realty, LLC

This 3 bedroom, 2.5 bath home offers the perfect blend of space, privacy, and convenience. Situated on just over an acre +/- outside of city limits, you can enjoy peaceful country living while still being less than a 10 minute drive to town. The spacious layout provides comfortable living with thoughtful updates throughout. A standout feature is the shop, which offers over a thousand square feet

Rachel Sitzes Poplar Bluff Realty Inc

Exceptional Poultry Farm Opportunity with a 1,800 sqft 3 bed 2 bath home that was built in 2020. Presenting a rare opportunity to acquire a modern, income-producing poultry operation. This farm has been meticulously maintained and is available due to the owners’ retirement. Designed with efficiency and productivity in mind, the property offers state-of-the-art facilities and equipment to support

Christy Lawrence C. Lawrence Realty LLC

Step into timeless charm with The Stallcup House, a grand historic estate built in 1909, nestled on 1.24 beautifully landscaped acres in the heart of Sikeston. This remarkable property spans two adjoining lots, zoned both residential and commercial, offering endless opportunities for living, entertaining, or business ventures. The main residence boasts over 5,000 square feet of refined

Lauren DeWitt EDGE Realty, ERA Powered

Located in the heart of Southeast Missouri, this 67-acre tract of land lies between I-55 and Highway AA in Sikeston. Enrolled in the Wetlands Reserve Program (WRP), this property offers prime recreational and conservation value, making it ideal for hunting and outdoor recreation. With easy access via nearby major highways and a secluded feel, the property combines convenience and privacy. As WRP

Lauren DeWitt EDGE Realty, ERA Powered

Located on the northwest corner of I-55 and I-57 inside Sikeston City limits, this ground is in a prime location for commercial development. This property can be accessed via Ables Road or County Line Road. Owner will subdivide into smaller tracts. There is power, water and sewer available, all provided by Sikeston Board of Municipal Utilities.

Tim Merideth Century 21 Premiere Realty

1.24 acres of commercial land located on the corner of Stallcup Drive and Lawrence Street. This lot is located beside a 60 unit apartment complex; and there is a Lowe's, JC Penney and Taco Bell within walking distance. Concrete streets. Located in New Madrid County, Sikeston city limits. Zoned light industrial.

Tim Merideth Century 21 Premiere Realty

Commercial land on a corner lot available for development in Sikeston's busiest retail area. 1.05 acres zoned light industrial is located directly across the street from Wal-Mart. Other major retailers located close by include JC Penney, Goodies, and Lowe's. Located in New Madrid county, Sikeston city limits.

Tim Merideth Century 21 Premiere Realty