Sikeston, MO Homes for Sale

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  /4

  $15,000

  • Land
  • 6,969 Sq Ft
  • $93,750 per Acre

  315 Jackson St, Sikeston, MO 63801

  Vacant residential lot ready for a buyer to build on. This is a 70 x 100 corner lot.

  Annie Harris Century 21 Premiere Realty

  315 Jackson St, Sikeston, MO 63801
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  /14

  $89,400

  • 2 Beds
  • 1 Bath
  • 1,000 Sq Ft

  406 W Gladys St, Sikeston, MO 63801

  Step inside this beautifully remodeled 2-bedroom, 1-bath home that’s move-in ready and full of modern updates! Fresh interior and exterior paint give the home a crisp, inviting look, while the brand-new flooring throughout adds warmth and style. Outside, the freshly painted exterior provides excellent curb appeal, and the manageable yard makes maintenance a breeze. Whether you’re a first-time

  Lawren McMullan EDGE Realty, ERA Powered

  406 W Gladys St, Sikeston, MO 63801
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  /2

  $90,000

  • 3 Beds
  • 1 Bath
  • 1,077 Sq Ft

  849 William St, Sikeston, MO 63801

  Enjoy entertaining in this 3-bedroom, 1-bath home with a spacious yard and separate dining room. Updates like the new dryer plug-in, baseboard heaters, fresh interior paint, kitchen cabinets, and sink add modern convenience while keeping maintenance low. Plus, the covered carport provides protected parking. Set up a showing today!

  Tasha Cardin EXP Realty, LLC

  849 William St, Sikeston, MO 63801
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  /3

  $42,500

  • Land
  • 16,988 Sq Ft
  • $108,974 per Acre

  419 Secretariat, Sikeston, MO 63801

  Welcome to Saddleridge South, 2nd Addition! Located inside the city limits of Sikeston, these lots have utilities already ran to them and are ready for construction to begin. You can be the general contractor, or we can introduce you to some of the area's finest builders to work with. Covenants and restrictions were crafted to help protect property value and are available upon request. These are

  Tim Merideth Century 21 Premiere Realty

  419 Secretariat, Sikeston, MO 63801
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  /4

  $65,000

  • Land
  • 3.78 Acres
  • $17,196 per Acre

  00 Illinois Ave, Sikeston, MO 63801

  Nearly 4 acres in a peaceful setting bordering a quiet neighborhood and adjacent to a park. This beautiful property offers endless potential - build your dream home, create a private retreat, or explore subdivision development opportunities. Enjoy the perfect balance of privacy and convenience with plenty of space to. Rare opportunity in a desirable location with natural surroundings and easy

  Rene Church Century 21 Premiere Realty

  00 Illinois Ave, Sikeston, MO 63801
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  /2

  $44,000

  • 4 Beds
  • 2 Baths
  • 1,300 Sq Ft

  408 Carroll St, Sikeston, MO 63801

  If you are looking for an investment property or a home that requires some TLC, this home is ready for your renovations. Priced to sell quickly, schedule your viewing today!

  Thomas Williams Century 21 Premiere Realty

  408 Carroll St, Sikeston, MO 63801
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  /14

  $3,960,000

  0 Ables Rd, Sikeston, MO 63801

  Located on the northwest corner of I-55 and I-57 inside Sikeston City limits, this ground is in a prime location for commercial development. This property can be accessed via Ables Road or County Line Road. Owner will subdivide into smaller tracts. There is power, water and sewer available, all provided by Sikeston Board of Municipal Utilities.

  Tim Merideth Century 21 Premiere Realty

  0 Ables Rd, Sikeston, MO 63801
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  /9

  $106,000

  • Land
  • 37,461 Sq Ft
  • $123,256 per Acre

  120 Cypress Branch Rd, Sikeston, MO 63801

  Greenfield North will be a gated, fenced cul-de-sac community located inside the city limits of Sikeston, just off Highway 61. You'll experience the convenience of town combined with the calm of a quiet neighborhood. Enjoy a private, secure location for your custom home. The covenants and restrictions were designed to help preserve property values and maintain a safe, high-quality, and

  Tim Merideth Century 21 Premiere Realty

  120 Cypress Branch Rd, Sikeston, MO 63801
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  /3

  $42,500

  • Land
  • 15,246 Sq Ft
  • $121,429 per Acre

  408 Secretariat, Sikeston, MO 63801

  Welcome to Saddleridge South, 2nd Addition! Located inside the city limits of Sikeston, these lots have utilities already ran to them and are ready for construction to begin. You can be the general contractor, or we can introduce you to some of the area's finest builders to work with. Covenants and restrictions were crafted to help protect property value and are available upon request. These are

  Tim Merideth Century 21 Premiere Realty

  408 Secretariat, Sikeston, MO 63801
• 

  

  /16

  $185,000

  • 2 Beds
  • 2 Baths
  • 1,365 Sq Ft

  1300 N Main St Unit 219, Sikeston, MO 63801

  Gated Community. Wow is the only words to describe you next home at The Residence at Maingate. This beautiful andwell maintain condo has it all. Two large bedrooms with on suite bathrooms. End unit that provides a lot of light. Private deckaccessible from one bedroom and main living area. Neutral paint color that coordinates with laminate flooring through out.

  Elaine Edgar Semo Home Realty

  1300 N Main St Unit 219, Sikeston, MO 63801
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  /8

  $9,330

  • 3 Beds
  • 1 Bath
  • 1,152 Sq Ft

  105 Adams St, Sikeston, MO 63801

  Opportunity awaits with this 3-bedroom, 1-bath home offering 1,152 sq. ft. of living space on a .23 acre lot. Built in 1972, this property features a functional single-level layout, metal roof, covered parking, and plenty of potential for an investor, flipper, or buyer ready to make it their own. The spacious yard provides room for outdoor living, gardening, or future improvements, while the

  Scott Harrison Delta Realty, LLC

  105 Adams St, Sikeston, MO 63801
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  /18

  $75,000

  • 2 Beds
  • 1 Bath
  • 850 Sq Ft

  838 E Gladys St, Sikeston, MO 63801

  Cute fully remodeled 2 bed 1 bath home just few houses down from the Sikeston High School. This home features new subfloors/joists, walls/ceilings, cabinets flooring, plumbing, electrical, water heater, and much more. Along with a spacious backyard. Right in the center of Sikeston and only walking distance to a lot of the amenities.

  Chris Mathes RE/MAX Platinum

  838 E Gladys St, Sikeston, MO 63801
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  /3

  $42,500

  • Land
  • 14,374 Sq Ft
  • $128,788 per Acre

  403 Secretariat, Sikeston, MO 63801

  Welcome to Saddleridge South, 2nd Addition! Located inside the city limits of Sikeston, these lots have utilities already ran to them and are ready for construction to begin. You can be the general contractor, or we can introduce you to some of the area's finest builders to work with. Covenants and restrictions were crafted to help protect property value and are available upon request. These are

  Tim Merideth Century 21 Premiere Realty

  403 Secretariat, Sikeston, MO 63801
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  /9

  $108,000

  • Land
  • 43,124 Sq Ft
  • $109,091 per Acre

  110 Cypress Branch Rd, Sikeston, MO 63801

  Greenfield North will be a gated, fenced cul-de-sac community located inside the city limits of Sikeston, just off Highway 61. You'll experience the convenience of town combined with the calm of a quiet neighborhood. Enjoy a private, secure location for your custom home. The covenants and restrictions were designed to help preserve property values and maintain safe, high-quality, and comfortable

  Tim Merideth Century 21 Premiere Realty

  110 Cypress Branch Rd, Sikeston, MO 63801
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  /22

  $169,000 Open Sun 1PM - 3PM

  • 3 Beds
  • 1.5 Baths
  • 1,302 Sq Ft

  116 Terrace Dr, Sikeston, MO 63801

  Jessica Merideth Century 21 Premiere Realty

  116 Terrace Dr, Sikeston, MO 63801
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  /2

  $69,900

  • 2 Beds
  • 2 Baths
  • 1,008 Sq Ft

  118 N 3rd St, Sikeston, MO 63801

  Welcome to this 2-bedroom, 2-bath ranch home—a perfect choice for a starter home or someone looking to downsize! Enjoy the ease of single-level living with a functional layout and plenty of natural light throughout. The home includes a detached garage, offering extra storage or workspace potential. With its classic design and solid bones, this property is full of potential to make it your own.

  Christina Essner EXP Realty, LLC

  118 N 3rd St, Sikeston, MO 63801
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  /2

  $45,000

  • 3 Beds
  • 1 Bath
  • 1,309 Sq Ft

  1140 Ruth St, Sikeston, MO 63801

  If you are looking for an investment property or a home that requires some TLC, this home is ready for your renovations. Priced to sell quickly, schedule your viewing today!

  Thomas Williams Century 21 Premiere Realty

  1140 Ruth St, Sikeston, MO 63801
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  /21

  $245,000 New Construction

  • 3 Beds
  • 2 Baths
  • 1,300 Sq Ft

  50 Byrd Dr, Sikeston, MO 63801

  Welcome to this stunning NEW construction home, thoughtfully designed with modern living in mind. This beautifully crafted residence features an open-concept floor plan that seamlessly connects the living, dining, and kitchen areas—perfect for both everyday living and entertaining. Offering 3 spacious bedrooms and 2 full bathrooms, the home provides comfort and functionality for a variety of

  Lawren McMullan EDGE Realty, ERA Powered

  50 Byrd Dr, Sikeston, MO 63801
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  /2

  $15,000

  • Land
  • 8,712 Sq Ft
  • $75,000 per Acre

  809 Bollweevil Blvd, Sikeston, MO 63801

  This vacant residential lot is ready for you to build on, and priced to help you get started quickly. Covenants and restrictions are in place to help protect your investment. Located inside Sikeston City Limits. Additional Rooms: In Platted Subdv.

  Tim Merideth Century 21 Premiere Realty

  809 Bollweevil Blvd, Sikeston, MO 63801
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  /2

  $59,900

  • 2 Beds
  • 1 Bath
  • 744 Sq Ft

  321 Benton St, Sikeston, MO 63801

  Investor Opportunity! This income-producing property offers solid potential with hardwood and tile floors throughout, combining durability with low-maintenance appeal. The fenced-in yard adds value for tenants seeking outdoor space, and the property's layout and location make it an attractive rental option. Whether you're expanding your portfolio or diving into your first investment, this is a

  Christina Essner EXP Realty, LLC

  321 Benton St, Sikeston, MO 63801
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  /9

  $27,500

  • 2 Beds
  • 1 Bath
  • 1,116 Sq Ft

  405 Branum St, Sikeston, MO 63801

  Investor Special in Sikeston! Opportunity awaits at 405 Branum St. This property has been partially gutted and is ready for your vision to bring it back to life. Major demo work has already been completed, saving you time and upfront labor. Whether you’re looking for your next fix-and-flip project, rental property, or long-term hold, this is a blank canvas with serious upside potential.

  Jonathan Adams Keller Williams Realty West

  405 Branum St, Sikeston, MO 63801
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  /2

  $48,000

  • 3 Beds
  • 2 Baths
  • 1,120 Sq Ft

  1205 W Murray Ln, Sikeston, MO 63801

  If you are looking for an investment property or a home that requires some TLC, this home is ready for your renovations. Priced to sell quickly, schedule your viewing today!

  Thomas Williams Century 21 Premiere Realty

  1205 W Murray Ln, Sikeston, MO 63801
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  /30

  $265,000

  • 3 Beds
  • 2 Baths
  • 1,980 Sq Ft

  218 Thomas Dr, Sikeston, MO 63801

  **Charming Family Retreat with Whimsical Touches!**Discover your dream home in this delightful all-brick house featuring 3 spacious bedrooms and 2 baths, perfect for families seeking comfort and style. Entertain in the inviting dining room or cozy up in the family room, complete with a charming fireplace that sets the scene for memorable gatherings. Step outside to a huge fenced backyard,

  Brandon Kielhofner EPM Real Estate

  218 Thomas Dr, Sikeston, MO 63801
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  /19

  $95,000

  • 2 Beds
  • 1 Bath
  • 1,045 Sq Ft

  302 Marshall St, Sikeston, MO 63801

  Welcome to this cozy 2 bed, 1 bath home on a desirable corner lot! Featuring a new heating unit, this property offers comfort and peace of mind. Whether you're a first-time buyer, looking to downsize, or searching for your next investment property, this home checks all the boxes. Affordable, manageable, and full of potential!

  Lynsey Perry Silverthorn Realty, LLC

  302 Marshall St, Sikeston, MO 63801
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  /14

  $99,900

  • 3 Beds
  • 1 Bath
  • 1,080 Sq Ft

  318 Kendall St, Sikeston, MO 63801

  Welcome home to this fully remodeled 3-bedroom, 1-bath charmer, offering modern comfort and timeless style. Every detail has been thoughtfully updated, including fresh flooring, contemporary fixtures, new paint, and an inviting open layout that maximizes both light and space. All three bedrooms are generously sized, providing flexibility for family, guests, or a home office. The updated bathroom

  Lawren McMullan EDGE Realty, ERA Powered

  318 Kendall St, Sikeston, MO 63801
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  /2

  $72,500

  • 2 Beds
  • 1 Bath
  • 1,049 Sq Ft

  733 Matthews Ave, Sikeston, MO 63801

  Are you a first time homebuyer or looking to expand your investment portfolio? This cozy 2 bedroom home might be just for you! This home is located in a quiet neighborhood, yet is conveniently located close to shopping centers, schools, and both mid-town and downtown. This home offers an eat-in kitchen, laundry room and full bathroom with tub all that have been newly updated. This home is great

  Katrina Dowell C. Lawrence Realty LLC

  733 Matthews Ave, Sikeston, MO 63801
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  /23

  $179,900

  • 3 Beds
  • 2 Baths
  • 2,919 Sq Ft

  908 Davis Blvd, Sikeston, MO 63801

  This story and a half has great curb appeal with mature trees and a large backyard with a shed and a storage room. Inside there is ample room for growth in this 3 bedroom 2 bath home with a full basement. Updated bathrooms have a modern flare and you can bring your creativity for the bedrooms and living space. The large dining room will provide great space for entertaining or regular family

  allen basham EXP Realty, LLC

  908 Davis Blvd, Sikeston, MO 63801
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  /26

  $285,500 Open Sun 2PM - 3:30PM

  • 4 Beds
  • 3 Baths
  • 2,400 Sq Ft

  904 Pine St, Sikeston, MO 63801

  Ashley Cross EPM Real Estate

  904 Pine St, Sikeston, MO 63801
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  /2

  $74,900

  • 3 Beds
  • 1 Bath
  • 1,252 Sq Ft

  512 S New Madrid St, Sikeston, MO 63801

  Great opportunity for investors! This 3-bedroom property offers solid potential as a rental or flip, with a manageable layout and room to add value. Whether you're expanding your portfolio or getting started in real estate, this is a smart, affordable option. Don't miss out on this income-producing opportunity—schedule a showing today to see the possibilities!

  Christina Essner EXP Realty, LLC

  512 S New Madrid St, Sikeston, MO 63801
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  /3

  $42,500

  • Land
  • 20,037 Sq Ft
  • $92,391 per Acre

  311 Citation Dr, Sikeston, MO 63801

  Come see Sikeston's newest subdivision! These are excellent sites for first-time home buyers, families, or those wanting to downsize. Turn south off Broadway onto South Illinois Avenue to two new cul-de-sacs, ensuring reduced traffic. This subdivision is inside Sikeston City limits, and has covenants and restrictions to help protect your investment. Super easy, fast access to Highway 60 and

  Tim Merideth Century 21 Premiere Realty

  311 Citation Dr, Sikeston, MO 63801
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  /30

  $242,900 New Construction

  • 3 Beds
  • 2 Baths
  • 1,400 Sq Ft

  166 Cypress Dr, Sikeston, MO 63801

  Welcome to this beautifully maintained 3 bedroom, 2 bathroom home in a great location in Sikeston. Built just 2 years ago, this home offers the perfect blend of modern design, quality craftsmanship, and everyday functionality. As you step inside, you’re welcomed by an open floor plan that creates a seamless flow between the living, dining, and kitchen areas that’s ideal for both entertaining and

  Paul Fox Mossy Oak Properties Mozark Re

  166 Cypress Dr, Sikeston, MO 63801
• 

  /2

  $15,000

  • Land
  • 10,454 Sq Ft
  • $62,500 per Acre

  804 Cotton Ridge Dr, Sikeston, MO 63801

  This vacant residential lot is ready for you to build on, and priced to help you get started quickly. Covenants and restrictions are in place to help protect your investment. Located inside Sikeston City Limits. Additional Rooms: In Platted Subdv.

  Tim Merideth Century 21 Premiere Realty

  804 Cotton Ridge Dr, Sikeston, MO 63801
• 

  /2

  $44,900

  • 2 Beds
  • 1.5 Baths
  • 576 Sq Ft

  136 N 6th St, Sikeston, MO 63801

  Great opportunity for investors! This 2-bedroom property offers solid potential as a rental or flip, with a manageable layout and room to add value. Whether you're expanding your portfolio or getting started in real estate, this is a smart, affordable option.

  Christina Essner EXP Realty, LLC

  136 N 6th St, Sikeston, MO 63801
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  /25

  $185,000

  • 3 Beds
  • 2 Baths
  • 1,527 Sq Ft

  303 Kramer Dr, Sikeston, MO 63801

  Welcome home to one of Sikeston’s most sought-after north-end neighborhoods. Step inside to discover a bright and inviting formal living room filled with natural light pouring through large windows, creating an inviting atmosphere. The spacious kitchen offers abundant counter space and cabinetry, along with a cozy breakfast area perfect for everyday meals. Just off the kitchen, the den features a

  Emily Deuster Century 21 Premiere Realty

  303 Kramer Dr, Sikeston, MO 63801
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  /36

  $309,500

  • 3 Beds
  • 2 Baths
  • 1,800 Sq Ft

  1201 Yosemite, Sikeston, MO 63801

  Welcome to this stunning 2023-built home offering the perfect blend of modern design, functionality, and comfort. Featuring 3 bedrooms, 2 bathrooms, and approximately 1,800 sq ft of living space, this property is thoughtfully designed for both everyday living and entertaining. Situated on a spacious corner lot within a brand-new subdivision, the home offers exceptional curb appeal along with a

  Shawn Adams Poplar Bluff Realty Inc

  1201 Yosemite, Sikeston, MO 63801
• 

  

  /3

  $42,500

  • Land
  • 13,939 Sq Ft
  • $132,812 per Acre

  414 Secretariat, Sikeston, MO 63801

  Welcome to Saddleridge South, 2nd Addition! Located inside the city limits of Sikeston, these lots have utilities already ran to them and are ready for construction to begin. You can be the general contractor, or we can introduce you to some of the area's finest builders to work with. Covenants and restrictions were crafted to help protect property value and are available upon request. These are

  Tim Merideth Century 21 Premiere Realty

  414 Secretariat, Sikeston, MO 63801
• 

  

  /11

  $169,900

  • 4 Beds
  • 2 Baths
  • 2,101 Sq Ft

  502 Jaycee St, Sikeston, MO 63801

  This well-maintained four-bedroom, two-bath home offers plenty of room to grow, plus a versatile bonus space that can serve as a fifth bedroom, home office, playroom, or anything you envision. Situated on a desirable corner lot, the property features a fully fenced backyard—perfect for pets, gardening, or outdoor entertaining. Step inside to a warm and inviting layout, beginning with an eat-in

  Scott Harrison Delta Realty, LLC

  502 Jaycee St, Sikeston, MO 63801
• 

  

  /9

  $106,000

  • Land
  • 35,283 Sq Ft
  • $130,864 per Acre

  130 Cypress Branch Rd, Sikeston, MO 63801

  Greenfield North will be a gated, fenced cul-de-sac community located inside the city limits of Sikeston, just off Highway 61. You'll experience the convenience of town combined with the calm of a quiet neighborhood. Enjoy a private, secure location for your custom home. The covenants and restrictions were designed to help preserve property values and maintain a safe, high-quality, and

  Tim Merideth Century 21 Premiere Realty

  130 Cypress Branch Rd, Sikeston, MO 63801
• 

  /2

  $400,000

  • Land
  • 2.63 Acres
  • $152,091 per Acre

  109 Stallcup Dr, Sikeston, MO 63801

  Over 2.5 acres of commercial property located in the heart of Sikeston's booming retail and hospitality area. Just a block from Wal-Mart Supercenter, 2 new hotels, shopping and restaurants, and a half mile to the intersection of US Highways 60 & 61. This is a premium location at an outstanding price.

  Tim Merideth Century 21 Premiere Realty

  109 Stallcup Dr, Sikeston, MO 63801
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  /26

  $259,000 Open Sun 1PM - 3PM

  • 3 Beds
  • 2 Baths
  • 1,828 Sq Ft

  126 Bradley Dr, Sikeston, MO 63801

  Recently remodeled and ready for Y-O-U!This great home is updated and move in ready! Improvements include all new flooring, windows, fixtures, and hardware—just to name a few. Bathrooms are spacious and have been tastefully modernized with new vanities, tile, and matching fixtures. The eat-in kitchen boasts beautiful quartz countertops, subway tile backsplash, and updated appliances. From the

  Jessica Merideth Century 21 Premiere Realty

  126 Bradley Dr, Sikeston, MO 63801

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