South Carolina Homes for Sale with a Guest House

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  /60

  $3,000,000

  • 5 Beds
  • 5.5 Baths
  • 7,401 Sq Ft

  804 Old Forge Rd, Chapin, SC 29036

  An extraordinary private estate on Lake Murray offering a level of space, craftsmanship, & waterfront access that is nearly impossible to replicate today. Situated on 2 beautifully landscaped acres with 242 feet of shoreline, this all-brick residence delivers over 6,000 sq.ft. of thoughtfully designed living, complemented by a two bath guest house—also all brick—creating a true multi-generational

  Michael DiMaria RE/MAX At The Lake

  804 Old Forge Rd, Chapin, SC 29036
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  /58

  $1,150,000 New Construction

  • 4 Beds
  • 3.5 Baths
  • 3,000 Sq Ft

  26 Longwood Dr, Okatie, SC 29909

  When you cross over the causeway into Callawassie Island, you are transported into a peaceful private world where moss-draped oaks, winding marsh views, and quiet coastal beauty instantly replace the pace of everyday life, creating a true sense of retreat the moment you arrive. Driving past beautifully manicured golf fairways woven seamlessly with natural wildlife habitat and serene lagoons,

  Robert Moul Moul, REALTORS

  

  26 Longwood Dr, Okatie, SC 29909
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  /46

  $2,400,000

  • 5 Beds
  • 5 Baths
  • 3,805 Sq Ft

  4637 Hagan Rd, Hollywood, SC 29449

  Known as the Toogoodoo River House, this extraordinary one-acre waterfront property is perched on a high bluff overlooking Toogoodoo Creek and the surrounding Lowcountry marshlands near Hollywood, South Carolina. Rich in history and character, the property features four unique historic structures that were carefully relocated and reconstructed on site during the 1990s and early 2000s, creating a

  Katie Poole The Exchange Company, LLC

  4637 Hagan Rd, Hollywood, SC 29449
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  /35

  $1,585,000 New Construction

  • 4 Beds
  • 3.5 Baths
  • 2,752 Sq Ft

  695 Distant Island Dr, Beaufort, SC 29907

  Be the first to reside in this exquisite Distant Island custom home, slated for completion in late 2026. Crafted for Low Country living, this 4-bedroom, 3.5-bathroom residence boasts an open concept design and premium finishes throughout. Enjoy the serene pond front setting from spacious porches, complemented by a 2-car detached garage featuring a complete guest suite. A short walk will lead you

  Jim Ware Tideland Realty Inc

  

  695 Distant Island Dr, Beaufort, SC 29907
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  /45

  $1,394,000

  • 7 Beds
  • 5.5 Baths
  • 5,140 Sq Ft

  492 Starr Ridge Rd, Gaffney, SC 29340

  Discover the perfect blend of privacy, comfort, and convenience with this extraordinary 72-acre farm estate—peacefully secluded yet located within an hour of Greenville, Charlotte, and the Tryon International Equestrian Center. Designed for those who value both refined living and the beauty of nature, this property offers a rare opportunity to enjoy country serenity without sacrificing

  Derek Worrell NorthGroup Real Estate LLC

  

  492 Starr Ridge Rd, Gaffney, SC 29340
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  /95

  $1,150,000

  • 4 Beds
  • 4.5 Baths
  • 3,976 Sq Ft

  25 Timber Trail, Beaufort, SC 29907

  Welcome to 25 Timber Trail, an exceptional Lowcountry residence located in the distinguished waterfront community of Cat Island. This expansive property blends traditional Southern architecture with coastal accents to deliver refined comfort. Purposefully designed for both everyday living and upscale entertaining, the home features spacious interiors complemented by abundant natural light, high

  Marsha Widenhofer BHHS Bay Street Realty

  

  25 Timber Trail, Beaufort, SC 29907
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  /33

  $1,050,000

  • 3 Beds
  • 2.5 Baths
  • 1,717 Sq Ft

  4881 Victoria Ave, North Charleston, SC 29405

  Welcome to 4881 Victoria Avenue, a thoughtfully renovated Park Circle home that blends historic character with modern functionality. This 3 bedroom, 2 bathroom main residence offers 1,717 square feet of beautifully curated living space, complemented by a fully equipped 816 square foot detached guest house (ADU) featuring 1 bedroom, 1 bathroom, and a full kitchen -- ideal for guests, or

  Jurgen Wagner Keller Williams Realty Charleston

  4881 Victoria Ave, North Charleston, SC 29405
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  /87

  $1,135,000

  • 3 Beds
  • 4 Baths
  • 3,138 Sq Ft

  255 Mallard Cove Rd, Prosperity, SC 29127

  PLEASE VIEW VIRTUAL TOUR LINK! Rare opportunity to own a true point lot on Lake Murray with approximately 400 feet of shoreline, Private Dock and Boat Ramp. The main residence is situated on a 0.75-acre homesite and is complemented by an adjacent 0.44-acre dock-approved, ready-to-build lot, offering exceptional flexibility and future potential. The 2,979 sq. ft. home features 3 bedrooms and 3

  Michael Murphy Lake Homes Realty LLC

  255 Mallard Cove Rd, Prosperity, SC 29127
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  /29

  $1,210,000

  • 3 Beds
  • 2 Baths
  • 1,360 Sq Ft

  227 Fishburne St, Charleston, SC 29403

  THREE Properties! Rare Downtown Opportunity - 227 Fishburne St, 229 Fishburne St, and 3 Woodall Court. An incredible opportunity to own multiple properties in the heart of downtown Charleston! 227 Fishburne Street, 229 Fishburne Street, and 3 Woodall Court are available for purchase individually or together, offering endless possibilities for renovation, expansion, or a spacious development

  Carmilla Brown Keller Williams Realty Charleston

  227 Fishburne St, Charleston, SC 29403
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  $1,290,000

  • 5 Beds
  • 4.5 Baths
  • 2,561 Sq Ft

  6 & 6.5 Addison St, Charleston, SC 29403

  2,561 Total SqFt! Welcome Home to your Downtown Double-Gem! Step into a realm of timeless elegance and contemporary luxury with this rare TWO-dwelling property, perfectly positioned in the vibrant heart of downtown Charleston in the North Central subdivision. The front residence at 6 Addison has been meticulously and fully rebuilt, featuring an inviting living area with a stunning exposed beams

  Nick Crane Realty ONE Group Coastal

  6 & 6.5 Addison St, Charleston, SC 29403
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  /120

  $1,299,000

  • 3 Beds
  • 2.5 Baths
  • 2,906 Sq Ft

  111 E Carolina Ave, Summerville, SC 29483

  Step into the charm of circa 1860 living with the comforts of thoughtful modern updates in the heart of Historic Summerville. Set on beautifully landscaped grounds, this three bedroom, two and a half bathroom property offers exceptional curb appeal and privacy, highlighted by a magnificent grand live oak, mature camellias, mature azaleas, and winding brick pathways that create a true garden oasis

  Taylor Charpia The Boulevard Company

  111 E Carolina Ave, Summerville, SC 29483
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  /107

  $1,350,000

  • 4 Beds
  • 6 Baths
  • 6,011 Sq Ft

  527 Wichman St, Walterboro, SC 29488

  The Elmore-Henderson House | c. 1821Some homes were built to impress. This one was built to endure.Established in the early 1820s by U.S. Congressman Franklin Harper Elmore, this historic Federal-style residence remains one of Walterboro's most significant and recognizable estates. Set behind gates on over seven private acres within the Hickory Valley Historic District, the property offers a rare

  Lisa Patterson Daniel Ravenel Sotheby's International Realty

  527 Wichman St, Walterboro, SC 29488
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  /100

  $1,399,000

  • 3 Beds
  • 3.5 Baths
  • 2,167 Sq Ft

  139 Cherry Point Rd S, Okatie, SC 29909

  There is a finite number of river waterfront properties left. This property is for the person who understands the value in obtaining 260 feet of riverfront. The community is a rural neighborhood hidden from the bustling activity of hwy. 170. This is not just a home for sale, it is a way of life. Nearly 1 acre on the tidal waters of the Okatie river with a privacy fenced-in yard, TWO lots, private

  Felice LaMarca BHHS Hilton Head Bluffton Real

  

  139 Cherry Point Rd S, Okatie, SC 29909
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  /40

  $1,299,999 Coming Soon

  • 9 Beds
  • 8 Baths
  • 4,116 Sq Ft

  2976 / 2980 Propst Rd, Clover, SC 29710

  Opportunity to own nearly 28 acres in Clover, SC with two homes, multiple outbuildings, and land set up for livestock and farming. This versatile property is well suited for multi-generational living, a working farm, or buyers looking for space, privacy, and long-term potential. The main brick farmhouse offers 4 bedrooms and 3.5 bathrooms with plenty of living space and classic character. The

  Kawthar Suleiman Alhambra Realty LLC

  

  2976 / 2980 Propst Rd, Clover, SC 29710
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  $1,195,000

  • 4 Beds
  • 5.5 Baths
  • 2,345 Sq Ft

  1317 Lakeview Dr, Manning, SC 29102

  Welcome to 1317 Lakeview Drive, a stunning fully renovated waterfront retreat on the shores of Lake Marion. This exceptional 4-bedroom, 51/2-bath home has been completely reimagined from top to bottom, blending modern luxury with the relaxed beauty of lakeside living.Step inside to an impressive open-concept floor plan highlighted by soaring tongue-and-groove wood ceilings with exposed beams,

  Stuart Hovermale Brand Name Real Estate

  1317 Lakeview Dr, Manning, SC 29102
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  /79

  $1,195,000

  • 4 Beds
  • 3.5 Baths
  • 3,346 Sq Ft

  55 Park Square N, Beaufort, SC 29907

  Rare brick home, 1 of only 2 in the River Front Community of Coosaw Point. Built for the builders daughter and completely updated by current owner, an artist/designer. A solid mahogany front door and copper lanterns warm the entrance. Solid oak flooring and 12 in crown molding and 8 in baseboards. Custom mill work and cabinets around gas fireplace. All hardware and plumbing fixtures have been

  Karen Godley Charter One Realty

  

  55 Park Square N, Beaufort, SC 29907
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  /66

  $1,075,000

  • 3 Beds
  • 2 Baths
  • 2,200 Sq Ft

  1373 Bridge St, Branchville, SC 29432

  Sportsman's paradise and duck hunter's haven! Large main house, guest cottage, expanded workshop, large barn, several out buildings, gorgeous ox bow water view with river access, abundant wildlife. Home has ornate glass work throughout, rustic living. Must see to appreciate.

  George Corley The Moore Group - A Division of the Litchfield Company

  1373 Bridge St, Branchville, SC 29432
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  /100

  $1,399,000 New Construction

  • 4 Beds
  • 2 Baths
  • 2,120 Sq Ft

  2021 Lafayette St, Beaufort, SC 29902

  This rare new-build estate offers a highly flexible three-residence setup on a single expansive lot, just minutes from historic downtown Beaufort and the Pigeon Point Boat Landing and Park. With close proximity to local shops, dining, and Waterfront Park, the location blends Lowcountry charm with everyday convenience.The estate includes a thoughtfully designed main residence of approximately

  Elijah Harris Greco Group Brokered by eXp

  

  2021 Lafayette St, Beaufort, SC 29902
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  /67

  $1,375,000

  • 5 Beds
  • 4.5 Baths
  • 3,361 Sq Ft

  2142 Golfview Dr, Charleston, SC 29412

  Tucked beneath a canopy of sweeping live oaks, this beautifully updated home is ideally located in the heart of Riverland Terrace--just moments from downtown Charleston and steps from the award-winning Charleston Municipal Golf Course. An automatic gate welcomes you to the property, providing privacy and ease of access to your spacious two-car garage. A blooming English garden entrance and

  Amy Byrne Compass Carolinas, LLC

  2142 Golfview Dr, Charleston, SC 29412
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  /96

  $1,475,000

  • 4 Beds
  • 3 Baths
  • 4,667 Sq Ft

  8347 Saint Lukes Church Rd, Newberry, SC 29108

  Looking for the perfect family farm or private estate? This custom-built, all-brick home with a metal roof is perfectly situated atop a hill overlooking 55 acres of beautiful, mostly pasture land, complete with a creek bordering the southern property line.Designed with accessibility in mind, the home is fully handicap accessible and features a heated and cooled three-car attached garage. Inside,

  Tara Berry Lake Murray Properties, Inc.

  8347 Saint Lukes Church Rd, Newberry, SC 29108
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  /18

  $1,100,000 New Construction

  • 4 Beds
  • 3.5 Baths
  • 1,872 Sq Ft

  911 7th St, Port Royal, SC 29935

  Welcome to your coastal oasis in the heart of Port Royal, SC! This stunning new construction home blends timeless Lowcountry charm with modern luxury in one of the area's most desirable locations. Just minutes from Sands Beach, local restaurants, coffee shops, and scenic trails like the Cypress Wetlands and Mossy Oak Trail, it offers the perfect combination of convenience and coastal

  Justin Keown BHHS Bay Street Realty

  

  911 7th St, Port Royal, SC 29935
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  /40

  $1,249,000

  • 3 Beds
  • 2 Baths
  • 1,568 Sq Ft

  212 E Hudson Ave, Folly Beach, SC 29439

  Welcome to the Folly Beach lifestyle with this beautifully renovated coastal cottage, perfectly located just steps from the beach access path. Every detail has been thoughtfully updated, including the HVAC system, septic, tankless water heater, custom kitchen, spacious primary bath, and fresh interior and exterior paint--trim, ceilings, and walls. While enhanced with modern comforts, the home

  Melissa Black AgentOwned Realty Preferred Group

  212 E Hudson Ave, Folly Beach, SC 29439
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  /75

  $487,500

  • 4 Beds
  • 2 Baths
  • 3,300 Sq Ft

  302 N 1st St, Cameron, SC 29030

  This charming Southern home offers the perfect blend of character, space, and versatility, set on approximately 1.5 acres in a peaceful small-town setting. With 3,300 square feet, this 4-bedroom, 2-bath residence provides plenty of room to spread out while maintaining a warm, inviting feel.Inside, you'll find beautiful hardwood floors and impressive 12 ft ceilings that enhance the home's timeless

  Ashby O'Cain Next Level Real Estate

  302 N 1st St, Cameron, SC 29030
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  $324,999

  • 4 Beds
  • 3 Baths
  • 2,377 Sq Ft

  1260 Pinecrest Dr, Lugoff, SC 29078

  Welcome to 1260 Pinecrest Drive in Lugoff, SC—a versatile all-brick property with exceptional potential for homeowners and investors alike. Situated on nearly an acre, this spacious 3-bedroom, 2-bathroom home spans 1,767 heated square feet and includes a detached apartment that adds 610 heated square feet of living space.The main home features timeless hardwood floors, an updated hall bathroom,

  Angelia Dodson Better Homes and Gardens Real Est Medley

  1260 Pinecrest Dr, Lugoff, SC 29078
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  /43

  $395,000

  • 3 Beds
  • 2 Baths
  • 1,344 Sq Ft

  50 Sea Pines Dr, Saint Helena Island, SC 29920

  Experience a private Lowcountry retreat at 50 Sea Pines Drive, set beneath a canopy of mature oaks just minutes from the beaches of St. Helena Island and Hunting Island State Park.The property offers a versatile layout featuring a main residence along with a detached guest space, creating opportunities for multi-generational living, rental income, or flexible use depending on your

  Valerie Romig Greco Group Brokered by eXp

  

  50 Sea Pines Dr, Saint Helena Island, SC 29920
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  /130

  $335,900 New Construction

  • 4 Beds
  • 3.5 Baths
  • 3,005 Sq Ft

  Bradley II Plan at Cottages at Roofs Pond, West Columbia, SC 29170

  The Bradley II offers 3,005 square feet of comfortable living space, thoughtfully designed with four bedrooms and three bathrooms. Several exterior elevations (A, B, B6, C, D, D4) are available, providing options for brick, stone, and siding combinations to personalize your home's curb appeal. The main level features an open floor plan, seamlessly connecting the spacious living room, dining area,

  Great Southern Homes Builder

  117 Judiths Path Unit 36475654, West Columbia, SC 29170
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  /35

  $625,000

  • 4 Beds
  • 3 Baths
  • 3,000 Sq Ft

  2854 Old Charleston Rd, Gilbert, SC 29054

  Turnkey Homestead Estate with Guest House on 5 Acres – Pool, Workshop, and Endless Possibilities Welcome to your private retreat in Gilbert, where comfort, space, and self-sufficient living come together on 5 beautiful acres. This thoughtfully designed 4-bedroom, 3-bath home offers over 3,000 square feet of living space, paired with a rare combination of features that make this property truly

  Charles Caughman Caughman Realty

  2854 Old Charleston Rd, Gilbert, SC 29054
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  /16

  $190,000

  • 5 Beds
  • 2 Baths
  • 3,216 Sq Ft

  1420 U S 52, Moncks Corner, SC 29461

  Remarkable opportunity to own one of the most visible locations between Moncks Corner and Bonneau. This old country store ran for years and just needs the right person to bring it back to where people shop in the store and hang out on the full front porch. The store has a residential dwelling attached to it that has a kitchen and living room plus 3 bedrooms. Also on the property is a 2 bedroom, 2

  Jay Law The Real Estate Firm

  1420 U S 52, Moncks Corner, SC 29461
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  /48

  $599,000

  • 5 Beds
  • 3.5 Baths
  • 2,790 Sq Ft

  209 Fairway Rd, Cheraw, SC 29520

  This incredible property spans a vast, corner lot in one of Cheraw’s most desirable neighborhoods. The primary residence offers 5 bedrooms and 3.5 bathrooms, with a flexible bonus room accessible from both the upstairs hallway and the downstairs kitchen area—ideal for a home office or extra living space. The downstairs features a beautifully renovated kitchen that opens to a spacious demand a

  Mary Anderson Lewis Realty

  

  209 Fairway Rd, Cheraw, SC 29520
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  /37

  $635,000

  • 3 Beds
  • 2 Baths
  • 1,493 Sq Ft

  4412 Holmes Ave, North Charleston, SC 29405

  Set on a rare double corner lot framed by grand, mature trees, 4412 Holmes Avenue offers the kind of space, flexibility, and turnkey condition that's increasingly hard to find.Fully renovated from top to bottom, this home blends thoughtful design with major system upgrades already completed--including a brand new HVAC system with all new ductwork, updated plumbing throughout, and a new 200-amp

  Richard Callari Birchin Lane Realty Advisors, LLC

  4412 Holmes Ave, North Charleston, SC 29405
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  /49

  $695,000

  • 3 Beds
  • 2.5 Baths
  • 2,978 Sq Ft

  6 Spring Knob Cir, Beaufort, SC 29907

  This well-designed ranch home offers 3 bedrooms, 2.5 baths, and a flexible layout ideal for both everyday living and entertaining. Inside, you'll find a dedicated office, a true dining room, laundry room, and two separate living areas, creating space to work, gather, and relax. The primary bedroom features a private en-suite bath, while additional bedrooms provide comfortable accommodations. Set

  Laura Chambers Keller Williams

  

  6 Spring Knob Cir, Beaufort, SC 29907
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  /70

  $7,200,000

  • 7 Beds
  • 7.5 Baths
  • 5,916 Sq Ft

  36 Society St, Charleston, SC 29401

  An extraordinary offering in the heart of historic Ansonborough -- where Charleston's past is not only preserved, but beautifully reimagined.Constructed in 1840 by Henry Street in the years following the Great Fire, this rare double-front Greek Revival residence stands as a lasting expression of resilience, craftsmanship, and architectural significance. Its stately masonry facade and iconic

  Jessica Lee AgentOwned Realty Co. Premier Group, Inc.

  36 Society St, Charleston, SC 29401
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  /135

  $1,500,000

  • 3 Beds
  • 2 Baths
  • 2,470 Sq Ft

  317 Sumter Ave, Summerville, SC 29483

  Welcome to the expansive porch of 317 Sumter Avenue. This circa 1884 Charming Cottage is more than you can imagine! The main house is 2470sq.ft and the totally remodeled apartment over the 4-bay (tandem) garage is 879sq.ft. What a wonderful use of 3349sq.ft for living. The entire home has been renovated with perfect touches. The front door opens to a traditional center hall with living space on

  Candice Pratt RE/MAX Southern Shores

  317 Sumter Ave, Summerville, SC 29483
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  /45

  $2,095,000

  • 5 Beds
  • 4.5 Baths
  • 2,804 Sq Ft

  4 Bogard St, Charleston, SC 29403

  Location. Flexibility. Income. All in one unbeatable Charleston property. Two Homes, One Lot, Prime Downtown Charleston! An exceptional opportunity in the heart of Historic Downtown Charleston--just one street off King Street. This versatile property offers two fully independent homes on a single lot, totaling 5 bedrooms of rentable and livable space in one of the city's most in-demand locations.

  Cynthia Beasley Coldwell Banker Realty

  4 Bogard St, Charleston, SC 29403
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  /60

  $1,595,000

  • 6 Beds
  • 6.5 Baths
  • 6,087 Sq Ft

  2884 Lake Rd, Ridgeway, SC 29130

  Beautiful custom-built home on Lake Wateree convenient to both Columbia and Charlotte with 230 feet of lakefront, stunning views, and an acre of land. Notable features include: high ceilings, heart pine floors, and gorgeous reclaimed Pecky cypress paneling; three kitchens with granite countertops, a butlers pantry, and prep sink; a master suite with private sitting room, fireplace, large soaking

  Mary Lane Sloan eXp Realty LLC

  2884 Lake Rd, Ridgeway, SC 29130
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  /60

  $775,000

  • 5 Beds
  • 6.5 Baths
  • 3,200 Sq Ft

  6440 Saint Anthony Dr, Hollywood, SC 29449

  Gracefully blending privacy, scale, and thoughtful design, this gated estate offers a rare opportunity to own a property that truly stands apart. From its expansive acreage and custom craftsmanship to its exceptional flexibility -- including two fully independent in-law suites -- this residence is perfectly suited for those who value both refined living and unmatched versatility.Set on a fully

  Mandy Law The Real Estate Firm

  6440 Saint Anthony Dr, Hollywood, SC 29449
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  /48

  $899,900

  • 4 Beds
  • 3 Baths
  • 2,483 Sq Ft

  105 Ocean Point Dr, Saint Helena Island, SC 29920

  Motivated Seller! Welcome to 105 Ocean Point, Fripp Island SC! This stunning real estate gem is located in the sought-after Fripp Island Resort, offering a coastal paradise that you'll never want to leave. With 4 bedrooms and 3 baths spread over 2,430 sqft, this home provides ample space for comfortable living and entertaining. As you step inside, you'll be captivated by the breathtaking views of

  Todd McDaniel BHHS Bay Street Realty

  

  105 Ocean Point Dr, Saint Helena Island, SC 29920
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  /67

  $559,900

  • 3 Beds
  • 2 Baths
  • 1,792 Sq Ft

  371 Rhode Dr, Cottageville, SC 29435

  PRICE REDUCTION! Rare multi-generational or income-producing property on 5.7 acres, all on one tax parcel. This unique estate features a brand-new primary residence, a renovated 1940s farmhouse rental, equestrian and farm facilities, and extensive land improvements.The primary home at 371 Rhode Dr is a new 3BR/2BA manufactured home with an open floor plan, abundant natural light, and a

  Rob Sanderson Carolina One Real Estate

  371 Rhode Dr, Cottageville, SC 29435
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  /37

  $370,900 New Construction

  • 4 Beds
  • 3.5 Baths
  • 2,510 Sq Ft

  Madeline II Plan at Beach Forest, Sumter, SC 29153

  Great Southern Homes Builder

  1980 Castlerock Dr Unit 36495119, Sumter, SC 29153
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  /67

  $2,275,000

  • 5 Beds
  • 5 Baths
  • 4,239 Sq Ft

  1244 Weston Rd, Hopkins, SC 29061

  Beautiful Colonial style home with over 4200 square feet nestled on 149 acres spread across 6 parcels. Surrounded by a 3 bedroom/2bath guest home, a 4 stall horse barn, with storage upstairs and a full bathroom, and fenced area for horses, this property has everything you are looking for. Behind the home is a shed large enough for a motor home and storage. Enter the home through a two story

  Janet Feimster Coldwell Banker Realty

  1244 Weston Rd, Hopkins, SC 29061

Showing Results 41 - 80, Page 2 of 5