Wayne County MO Homes for Sale

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  /7

  $24,900

  • Land
  • 1.22 Acres
  • $20,410 per Acre

  CR 453 Lots 393 394 395 396 & 729 730 731, Piedmont, MO 63957

  Looking for a river getaway? This 1.22-acre property offers 7 lots in the Black River Retreat #2 subdivision. Partially cleared and featuring a nice mix of open space and mature trees, this property offers the perfect setting for a camper, cabin, or future getaway. Enjoy scenic views and easy access to the Black River just a short distance away. Electric is nearby, making development even more

  Matthew D'Amico Poplar Bluff Realty Inc

  CR 453 Lots 393 394 395 396 & 729 730 731, Piedmont, MO 63957
• 

  

  

  /5

  $32,999

  • Land
  • 2.92 Acres
  • $11,301 per Acre

  1105 Wayne 521a, Wappapello, MO 63966

  Discover this 2.92-acre residential lot in the Wappapello area of Wayne County. Featuring gently sloped, wooded terrain, the property offers a peaceful natural setting with plenty of privacy and a scenic forested environment. Public water is available, adding convenience for future development. Located in a quiet rural setting, the property provides a relaxed lifestyle while still offering access

  Joel Hinckley PlatLabs, LLC

  

  1105 Wayne 521a, Wappapello, MO 63966
• 

  

  

  /35

  $239,500

  • 3 Beds
  • 2 Baths
  • 1,128 Sq Ft

  1131 Wayne Route V, Piedmont, MO 63957

  Welcome to 1131 Wayne Route V. This 3 bedroom, 2 bath home has recently been totally remodeled from top to bottom. Brand new features include wall coverings, floor coverings, all electrical fixtures, all plumbing fixtures, all new windows, interior doors, stainless steel counter tops and more. Look over the pictures, most everything you see is brand new! The exterior just got a new paint job and

  Steve Johnson Poplar Bluff Realty Inc

  1131 Wayne Route V, Piedmont, MO 63957
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  /4

  $39,999

  • Land
  • 3.02 Acres
  • $13,245 per Acre

  205 Pisos Frst Dr, Wappapello, MO 63966

  Discover this 3.02-acre residential lot in the Wappapello area of Wayne County. Featuring sloped, wooded terrain, the property offers a peaceful natural setting surrounded by mature trees and the quiet beauty of southeastern Missouri. Located in a rural area with no HOA restrictions, it provides flexibility for a future home or retreat while maintaining privacy and space. The Wappapello region is

  Joel Hinckley PlatLabs, LLC

  

  205 Pisos Frst Dr, Wappapello, MO 63966
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  /60

  $995,000

  • 2 Beds
  • 2.5 Baths
  • 1,800 Sq Ft

  0 State Highway 49 Unit MIS26039731, Mill Spring, MO 63952

  It's rare to find a property that checks every single box, but this 147.8 acre +/- tract manages to pull it off. Offering an unmatched mix of privacy, convenience, and rugged natural beauty, this land features over 1900 feet of black river frontage, easy highway access and a creek that runs through the property. Best of all, it is bordered on the north and south sides by protected National

  Benjamin Vancil Mossy Oak Properties Mozark Re

  0 State Highway 49 Unit MIS26039731, Mill Spring, MO 63952
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  /6

  $87,500

  • Land
  • 25 Acres
  • $3,500 per Acre

  25 Acres, Lowndes, MO 63951

  Escape to your own private retreat with approximately 25 acres located in the highly desirable Turkey Creek Resort in Lowndes, Missouri. This secluded property offers the perfect blend of recreation, relaxation, and natural beauty. Turkey Creek Resort features three lakes, each with boat ramps, swimming access, and community beach areas for landowners and their guests to enjoy. Exciting

  Karen Cook Young Real Estate LLC

  25 Acres, Lowndes, MO 63951
• 

  

  /19

  $75,000

  Pending

  • 1 Bed
  • 1 Bath
  • 560 Sq Ft

  722 E Daniels St, Piedmont, MO 63957

  Discover the potential at 722 East Daniels St in Piedmont MO. Two manufactured homes offering a unique opportunity to craft your ideal living space. This property presents the option to live in one and rent out the other or rent them both for an income. Both homes were built in 2016, on concrete slabs, and each had new metal roofs installed in April of 2026. Both have the following, 1-bedroom,

  Gail Lumsden Farm & Home Realty

  722 E Daniels St, Piedmont, MO 63957
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  /27

  $200,000

  Pending

  • 3 Beds
  • 2 Baths
  • 1,400 Sq Ft

  122 Whitney Ln, Piedmont, MO 63957

  Clearwater Lake Home. Charming ranch home with many recent updates including public water and septic. Three bed & two bath home, with plank flooring, newer heat/air, kitchen appliances, washer & dryer, and attached and detached garages. Covered front porch and an open back deck. Room for storage of boats, camper, or lake related toys. Located one mile from Clearwater Lake where you can boat,

  Gail Lumsden Farm & Home Realty

  122 Whitney Ln, Piedmont, MO 63957
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  /25

  $139,900

  • 3 Beds
  • 1.5 Baths
  • 1,433 Sq Ft

  10843 Wayne Route D, Greenville, MO 63944

  Tucked away on 0.94 secluded acres, this beautifully updated 3-bedroom, 1.5-bath home offers the perfect blend of privacy and convenience. Featuring a full basement, attached garage, and detached carport, there’s plenty of room for storage, hobbies, and outdoor recreation. Recent updates throughout the home provide modern comfort while maintaining its inviting charm. Located just minutes from

  Matthew D'Amico Poplar Bluff Realty Inc

  10843 Wayne Route D, Greenville, MO 63944
• 

  

  /26

  $225,000

  • 3 Beds
  • 2 Baths
  • 1,064 Sq Ft

  1178 Wayne Route V, Piedmont, MO 63957

  Country home on 2.7 acres m/l with nice, shaded yard. Charming, wood-sided house has a covered front porch, attached 1-car carport, wrap around deck for entertaining, enjoying nature or just getting away to relax. Back yard has some fencing and 3 chicken houses, portable carport and detached shop/garage. Home has beautiful, real wood floors, spacious open floor plan living room, kitchen with

  Libby Clark Poplar Bluff Realty Inc

  1178 Wayne Route V, Piedmont, MO 63957
• 

  

  /37

  $219,900

  • 3 Beds
  • 1 Bath
  • 1,682 Sq Ft

  18198 State Highway 34, Piedmont, MO 63957

  Enjoy the beautiful views from the covered front porch of this cozy log home. The open floor plan, living room, kitchen and dining room with vaulted ceiling, stone fireplace, offer the perfect place to spend a night in. Updated kitchen and flooring throughout. Spacious bedroom, with adjoining smaller room, could be an office or nursery. Laundry and main bath combo with tub and shower. Upstairs

  Libby Clark Poplar Bluff Realty Inc

  18198 State Highway 34, Piedmont, MO 63957
• 

  

  /22

  $139,900

  • 3 Beds
  • 1 Bath
  • 1,040 Sq Ft

  418 N 2nd St, Piedmont, MO 63957

  Cute, cute, cute! These are the words to describe this newly remodeled and updated house. New flooring, fixtures, paint, plumbing, heat and air, roof and shutters. Cozy, roomy living room with new fan and tin ceiling, kitchen with small bar, rustic cabinets, new countertops and appliances, all adjoining a separate dining room. Charming barn doors offer privacy and save space. Bath has a walk-in

  Libby Clark Poplar Bluff Realty Inc

  418 N 2nd St, Piedmont, MO 63957
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  /10

  $99,900

  Pending

  • Land
  • 39 Acres
  • $2,562 per Acre

  0 Wayne 434 County, Piedmont, MO 63957

  This 39 m/l acre tract borders Mark Twain National forest land on two sides. Wayne County road 434 runs through it providing road frontage. There is a forest service road going through the larger tract also. Electric poles go along CR 434 so getting power to this land is not a major deal. There are some nice building spots for a home or a hunting cabin. The recreational and hunting possibilities

  Steve Johnson Poplar Bluff Realty Inc

  0 Wayne 434 County, Piedmont, MO 63957
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  /14

  $60,000

  • 2 Beds
  • 0.5 Baths
  • 672 Sq Ft

  156 River Rd, Piedmont, MO 63957

  Escape to your own peaceful retreat near Clearwater Lake and the Black River! This 600 sq. ft. m/l unfinished cabin offers the perfect opportunity to create the getaway you've envisioned. Nestled on a level lot with electric, well, and septic already in place. There is loft space on both ends, with room to add on if needed. The property provides a solid foundation for your finishing touches.

  Lexi Carter Poplar Bluff Realty Inc

  156 River Rd, Piedmont, MO 63957
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  /69

  $979,999

  $5K PRICE DROP

  • Land
  • 259.31 Acres
  • $3,779 per Acre

  1371 Wayne 344, Des Arc, MO 63636

  Amazing farm featuring a stunning custom home on 259.3 +/- acres in beautiful Southern Iron and Northern Wayne County! The home has LP Smart Siding. This gorgeous ranch-style home is perfectly elevated to capture breathtaking views across the rolling fields and countryside. Inside, you’ll find an open-concept living, dining, and kitchen area designed for comfort and entertaining. The chef’s

  

  Bobbie Browne

  RE/MAX Best Choice

  (573) 859-4314

  1371 Wayne 344, Des Arc, MO 63636
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  /4

  $24,999

  • Land
  • 3.17 Acres
  • $7,886 per Acre

  195 Valley Dr, Piedmont, MO 63957

  Explore this 3.17-acre residential corner lot in the Piedmont area of Wayne County. Featuring gently sloped, partially wooded terrain, the property offers an ideal setting for a custom home while providing plenty of space and privacy. Located in a quiet neighborhood with no HOA, it combines a peaceful rural atmosphere with convenient access to local amenities, schools, and nearby highways.

  Joel Hinckley PlatLabs, LLC

  195 Valley Dr, Piedmont, MO 63957
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  /37

  $419,900

  • 3 Beds
  • 2 Baths
  • 2,838 Sq Ft

  961 Wayne 519, Wappapello, MO 63966

  2 homes built in 2021 and 10 secluded acres (m/l) The main home is appx 1,832 sq ft and features 3 bedrooms, 2 bathrooms, an open floor plan, vaulted and coffered ceilings, split bedroom floor plan, concrete countertops, crown molding, modern lighting, huge primary suite with office/sunroom, front and rear covered decks with amazing views, outdoor kitchen with pellet smoker and flat top grill and

  Gina Ginocchio Borrowed Time Real Estate

  961 Wayne 519, Wappapello, MO 63966
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  /37

  $330,000

  • 3 Beds
  • 2.5 Baths
  • 3,538 Sq Ft

  197 Wayne 340, Piedmont, MO 63957

  Located at 197 Wayne 340, Piedmont, MO 63957, this single-family residence, promises a unique opportunity to create your ideal living space. HVAC installed in 2022, new roof in 2023, mini split in basement installed March 2025, new guttering and downspouts installed in November 2024, new natural gas water heater and new washer and gas dryer. The interior has new drywall and fresh paint, luxury

  Renee Williams Farm & Home Realty

  197 Wayne 340, Piedmont, MO 63957
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  /36

  $184,900

  Under Contract

  • 2 Beds
  • 2 Baths
  • 1,488 Sq Ft

  129 People Creek Rd, Wappapello, MO 63966

  Nestled on 3.5+/- acres in the heart of the Lake Wappapello area, this unique 2-bedroom, 2-bath earth home offers comfort, privacy, and convenient access to some of the area's best outdoor recreation. Inside, you'll find an open floor plan with a spacious living area, large dining room, and an oversized primary suite designed for comfort and functionality. The property also features an unfinished

  Matthew Tubb Mossy Oak Properties Mozark Re

  129 People Creek Rd, Wappapello, MO 63966
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  /70

  $264,900

  Under Contract

  • 3 Beds
  • 2 Baths
  • 1,960 Sq Ft

  3822 Wayne Route Bb, Greenville, MO 63944

  Escape to the Ozarks with this private 42+/- acre property located at 3822 Wayne Route BB in Greenville, Missouri. Tucked away at the end of the road, this secluded retreat offers unmatched privacy while adjoining thousands of acres of Mark Twain National Forest and sitting less than 2 miles from the Page Branch boat ramp on Wappapello Lake, making it a true outdoorsman's dream. The property

  Matthew Tubb Mossy Oak Properties Mozark Re

  3822 Wayne Route Bb, Greenville, MO 63944
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  /50

  $565,000

  • 3 Beds
  • 3.5 Baths
  • 2,600 Sq Ft

  877 Wayne 331, Piedmont, MO 63957

  Experience the perfect blend of country charm, modern comfort, and self-sufficient living on this beautiful 25± acre farm just outside of Piedmont, Missouri. With breathtaking views, fenced pasture, and infrastructure already in place for livestock, gardening, and homesteading, this property is ready for your rural lifestyle dreams.The land is fully fenced and features automatic livestock

  Ridge Huff Rooted Real Estate & Auction Co.

  877 Wayne 331, Piedmont, MO 63957
• 

  

  /25

  $85,000

  Pending

  • 3 Beds
  • 1 Bath
  • 1,274 Sq Ft

  65 Private Dr 143-9, Mill Spring, MO 63956

  This 1274 square ft. home offers two bedrooms (could be 3), one bath, large kitchen/dining combo, laundry room, living room and large family room. The living room and one bedroom have beautiful, pine, tongue & groove car siding on the walls. The home has updated, insulated windows and a complete new 3 ton HVAC system was installed in 2023. This home is located just off Hwy 143 just down the road

  Steve Johnson Poplar Bluff Realty Inc

  65 Private Dr 143-9, Mill Spring, MO 63956
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  /6

  $16,750

  • Land
  • 5.71 Acres
  • $2,933 per Acre

  00 NE 6th St, Mill Spring, MO 63952

  Discover the perfect spot to build your dream home, weekend getaway, or recreational retreat on this beautiful 5.71-acre lot in Mill Spring, Missouri. Enjoy the peace and privacy of country living while being just minutes from the Black River, offering easy access to fishing, floating, swimming, and camping. This property provides plenty of room to spread out and enjoy the outdoors. Need more

  Tonya Carter Century 21 American Realty

  00 NE 6th St, Mill Spring, MO 63952
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  /7

  $19,500

  • Land
  • 20,037 Sq Ft
  • $42,391 per Acre

  0 County Road 453 Unit MIS26036771, Piedmont, MO 63957

  This is a great spot to build a cabin, park a camper or both! These four lots sit at the top of the hill on CR 453 in Black River Retreat #2. The lots combine for almost a half an acre. This property has a gentle slope to it but is mostly level and is easily accessed from the county road. There is an electric pole close so getting power to the property will be easy. This would make a great place

  Steve Johnson Poplar Bluff Realty Inc

  0 County Road 453 Unit MIS26036771, Piedmont, MO 63957
• 

  

  /75

  $299,000

  • 2 Beds
  • 1 Bath
  • 880 Sq Ft

  1520 Madison 9346, Silva, MO 63964

  This private and secluded, excellent hunting property is located just south of Fredericktown, off County Road 325. The two-bedroom, one-bathroom home has been used as a full-time residence, but would also serve as a perfect hunting and weekend getaway cabin. The self-sufficient home has two 1,500-gallon water tanks for rain collection and electric with solar power backup. The property has a

  Carter Roth Whitetail Properties Real Estate, LLC

  1520 Madison 9346, Silva, MO 63964
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  /6

  $16,750

  • Land
  • 5.57 Acres
  • $3,007 per Acre

  0 6th St, Mill Spring, MO 63952

  Discover the perfect spot to build your dream home, weekend getaway, or recreational retreat on this beautiful 5.57-acre lot in Mill Spring, Missouri. Enjoy the peace and privacy of country living while being just minutes from the Black River, offering easy access to fishing, floating, swimming, and camping. This property provides plenty of room to spread out and enjoy the outdoors. Need more

  Tonya Carter Century 21 American Realty

  0 6th St, Mill Spring, MO 63952
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  /39

  $309,000

  • 3 Beds
  • 2 Baths
  • 1,988 Sq Ft

  633 Wayne 339a, Piedmont, MO 63957

  This is an incredible opportunity to purchase a home that has never been on the market. This 1988 square foot home is all on one level and features 3 bedrooms 2 full baths. It has beautiful hardwood flooring, and ceramic tile in the bathrooms. The large living room, dining, and kitchen provide open concept living. There are two bedrooms and one bath on one end of the home, and the primary suite

  Lexi Carter Poplar Bluff Realty Inc

  633 Wayne 339a, Piedmont, MO 63957
• 

  /2

  $65,000

  • 2 Beds
  • 1 Bath
  • 688 Sq Ft

  727 Eastwood St, Piedmont, MO 63957

  Stephanie Knoppe Mossy Oak Properties Mozark Re

  727 Eastwood St, Piedmont, MO 63957
• 

  

  /15

  $218,000

  New Construction

  • 3 Beds
  • 3 Baths
  • 1,760 Sq Ft

  2601 County Road 517, Wappapello, MO 63966

  Welcome to a rare real estate opportunity combining contemporary design, energy efficiency, and expansive outdoor space. Situated on a sprawling, serene 1-acre lot, this brand-new construction duplex offers the perfect layout for an owner-occupant looking for rental income, a multi-generational family, or an investor seeking a high-yield property.Both units boast a sleek, modern interior

  Stephanie Knoppe Mossy Oak Properties Mozark Re

  2601 County Road 517, Wappapello, MO 63966
• 

  

  /12

  $49,900

  • 2 Beds
  • 1 Bath
  • 644 Sq Ft

  1097 Wayne 459, Piedmont, MO 63957

  Completely remodeled and move in ready! Cute and comfortable mobile home sitting on a level, wooded, corner lot. Open floor plan, living room, kitchen and dining room, split floor plan, 2 bedrooms and one bath. Front and back decks for entertaining or just sitting and relaxing. Nice starter home or weekend getaway. Black River Retreat gives you access to community boat launch and swimming.

  Libby Clark Poplar Bluff Realty Inc

  1097 Wayne 459, Piedmont, MO 63957
• 

  

  /86

  $895,000

  • 3 Beds
  • 2.5 Baths
  • 2,599 Sq Ft

  352 Madison Wayne 9305, Marquand, MO 63655

  Welcome to your own private retreat in Marquand! Nestled on 100 mostly wooded acres and bordered by Big Creek along one side, this incredible property offers the perfect blend of country living, recreation, and equestrian amenities. Explore riding trails perfect for horses or ATVs, enjoy the privacy of your own private pond, and experience the natural beauty this property provides.The 3

  

  Kim Hutson

  Coldwell Banker Hulsey

  (573) 488-5775

  352 Madison Wayne 9305, Marquand, MO 63655
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  /11

  $85,000

  $35K PRICE DROP Pending

  • 3 Beds
  • 1 Bath
  • 865 Sq Ft

  240 Wayne 512, Wappapello, MO 63966

  Fully furnished Mobile Home on 3.5 wooded acres in a secluded area near Wappapello Lake. Included with the property is a one car portable carport, a 30x30 heated and cooled building suitable for family gatherings, fish fries, and get togethers. Also included is a smaller open front building used for cooking and barbequing and an 18x20 storage shed. The Mobile Home features an 8x11 porch.

  Harvey Graham HARVEY GRAHAM & ASSOC. REALTY

  240 Wayne 512, Wappapello, MO 63966
• 

  

  /99

  $2,200,000

  $300K PRICE DROP Pending

  • 14,628 Sq Ft

  5019 Wayne 380, Patterson, MO 63956

  This beautiful property is located along Wayne 380, just northwest of Greenville. This property was formerly used as a school and ministry in the past but has endless possibilities. The schoolhouse contains a commercial kitchen, dining hall, locker rooms with bathrooms and showers, dorms, apartments, and multiple large rooms to fit any of your needs. A venue building is also on the property and

  Carter Roth Whitetail Properties Real Estate, LLC

  5019 Wayne 380, Patterson, MO 63956
• 

  

  /78

  $448,000

  Pending

  • 800 Sq Ft

  001 Wayne 224a, Hiram, MO 63944

  This 160 acre property in Wayne County, Missouri offers an outstanding combination of privacy, recreation, and utility. The land includes a rustic cabin— equipped with electric, well, and septic—making it ideal for weekend stays, a hunting camp, or a future build site. Multiple work sheds and equipment barns provide excellent storage for tractors, implements, and hunting gear. Roughly 15 acres of

  Jason Stokes Midwest Land Group LLC

  001 Wayne 224a, Hiram, MO 63944
• 

  

  /49

  $399,900

  115 Madison Wayne 9305, Cascade, MO 63655

  Discover an outstanding 115.08 surveyed-acre recreational tract in Wayne County, Missouri, featuring year-round live water, excellent hunting opportunities, and multiple potential building locations. A spring-fed creek flows through the property, providing a reliable water source for wildlife while adding tremendous scenic appeal to this diverse Ozark landscape. Recently subjected to a selective

  Jason Stokes Midwest Land Group LLC

  115 Madison Wayne 9305, Cascade, MO 63655
• 

  

  /16

  $84,900

  • 3 Beds
  • 1 Bath
  • 1,056 Sq Ft

  110 Navajo St, Piedmont, MO 63957

  Looking for a home in Piedmont? This charming 3 bedroom, 1 bath home offers 1,056 square feet of comfortable living space with an open floor plan that’s perfect for everyday living and entertaining. Outside, you’ll find a spacious 24’ x 16’ storage shed, a covered patio for relaxing evenings, and a one-car carport for convenient parking. Whether you’re a first-time homebuyer, downsizing, or

  Natali Ketcherside Century 21 American Realty

  110 Navajo St, Piedmont, MO 63957
• 

  

  /45

  $460,000

  6483 Wayne Route P, Lowndes, MO 63951

  Discover an exceptional 115+/- acre recreational and hunting farm in Lowndes, Missouri, offering the perfect blend of seclusion, wildlife habitat, and build-site potential. With convenient highway frontage and multiple elevated building locations, this property provides breathtaking views and endless opportunities for a dream home, hunting retreat, or weekend getaway. Outdoor enthusiasts will

  Justin Parker Mossy Oak Properties Mozark Re

  6483 Wayne Route P, Lowndes, MO 63951
• 

  

  /47

  $175,000

  • 2 Beds
  • 2 Baths
  • 1,008 Sq Ft

  404 Ridgeview Dr, Piedmont, MO 63957

  Nestled on a gentle, tree dotted lot that backs up to a peaceful wooded area, this updated two bedroom ranch offers comfortable one level living with a fully finished walkout basement. The main floor features a bright living room, a dining area, and a kitchen equipped with a dishwasher, electric oven, and refrigerator, all tied together with durable luxury vinyl plank flooring. Both main floor

  Todd Henson Trust Realty, LLC

  404 Ridgeview Dr, Piedmont, MO 63957
• 

  

  /26

  $199,900

  • Land
  • 40 Acres
  • $4,998 per Acre

  TBD Wayne, Piedmont, MO 63957

  Rare opportunity to own 40 private acres just minutes from Black River, Sam A. Baker park, and Clearwater Lake, featuring prime hunting land with thriving deer and turkey populations. Property includes an established food plot, hilly terrain with peaceful valleys, several picturesque building sites, and valuable marketable timber. A perfect blend of seclusion, recreation, and natural beauty.

  Jenny Elliott Mossy Oak Properties Mozark Re

  TBD Wayne, Piedmont, MO 63957
• 

  

  /43

  $279,900

  Pending

  000, Piedmont, MO 63957

  Located just minutes west of Piedmont along County Road 353, this beautiful 80 +/- acre farm offers an outstanding combination of hunting, recreation, and agricultural opportunity. Featuring approximately 30 acres of open pasture with the balance in rolling hardwood timber, the property is well suited for cattle production, outdoor recreation, or a future homestead. The farm has great county road

  Jason Stokes Midwest Land Group LLC

  000, Piedmont, MO 63957

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