Palisade, CO Homes for Sale with Acreage

Nestled in the heart of Palisade’s renowned fruit and wine country, surrounded by vineyards, orchards, and mountain views, Vista & Vineyards Bed and Breakfast offers a rare blend of lifestyle, flexibility, and proven income potential. This well-established and highly rated BnB is a favorite among wine lovers, cyclists, and travelers seeking an authentic Colorado getaway. The 363sf detached

Chanel Crumbaugh Century 21 Elevated Real Estate

There’s something truly different about this Palisade home. Maybe it’s the layout - a little whimsical, a little practical - offering unique spaces around every corner. Maybe it’s the yard, full of character and charm. Or maybe, it’s the feeling you get when you’re here - like the rest of the world melts away. Come see for yourself why this one is so special. Perfectly situated in Palisade wine

MELISSA ROLBIECKI THE CHRISTI REECE GROUP

Spacious country retreat with room for everyone! This incredible 6-bedroom home sits on 34.14 acres and offers the perfect blend of comfort, character, and breathtaking views of the Grand Mesa. Designed with space in mind, the home features 2 primary suites plus 2 non-conforming bedrooms with closets, providing flexible living options for large households, guests, hobbies, or office space. The

Toni Heiden Heiden Homes Realty

Major Price Improvement — Now Offered at $850,000!! This beautifully updated ranch with amazing views on 5.6 fully irrigated acres in coveted SE Palisade now represents an exceptional opportunity to own one of the area's most desirable acreage properties. Perfectly positioned among Palisade's vineyards and orchards, the property captures unobstructed views of Mount Garfield, the Palisade Valley,

Josh McGuire RE/MAX 4000, INC

Unique opportunity for sweat equity! Orchard Mesa Greenhouse was established in 1988. The property is poised for complete renovation or Buyer may choose to start with a fresh new build to suit their specific business vision. This Nexus-built greenhouses 87,000+ Sq. Ft plus commercial building with office and break room offers multiple individually controlled greenhouses for plants, water walls

Jeptha Sheene Compass Colorado, LLC - Boulder

Experience luxury living at 480 Desert Bluff Court in Palisade, Colorado. This beautiful modern farmhouse is 2,656sqft and sits on 1.5± acres at the base of the Grand Mesa, offering direct access to BLM land from your backyard. The home features 4 bedrooms and 4 bathrooms, along with a 3-car garage that includes a 220 outlet and built-in shelves. Outside, you'll find a heated saltwater pool and

Caitlin Lucchesi United Country Real Colorado Properties

OPEN TO OFFERS! Welcome to 3697 F Road, a vineyard haven in Palisade where sun-soaked vines, thoughtful upgrades, and warm, inviting interiors come together in that effortless, “this feels like home” kind of way. Set on almost 5 gorgeous acres, including 3.5 acres of producing Syrah and Riesling grapes, this property is equal parts lifestyle and legacy. The vineyard is fully irrigated by a

MELISSA ROLBIECKI THE CHRISTI REECE GROUP

Sought-after Opportunity in Palisade with major agritourism potential! Located on 2.48 irrigated acres with prime Highway 6 frontage, this high-traffic site offers endless opportunities to expand, reinvent, or create your dream business in the heart of Colorado’s fruit and wine country. The property features a beautifully remodeled 3-bedroom home, a large retail and tasting room space, attached

Laura Black RE/MAX 4000, INC

Beautifully renovated home in the heart of Palisade offering five spacious bedrooms and two bathrooms. This property features all-new HVAC, roof, windows, siding, and partial electrical upgrade—providing peace of mind and modern comfort throughout. Situated on an irrigated one-acre lot, the possibilities are endless. Enjoy ample RV parking and a three-car garage, perfect for all your toys,

Karina Parenteau HUMMEL REAL ESTATE

Situated on 6.3 acres with irrigated fields featuring a pond, and a creek that runs behind the home this 4BR/3BA single-family home at 311 34 Rd in Palisade offers approximately 2,205 sqft of living space. The home includes an open kitchen with granite countertops and a large pantry, providing ample workspace and storage. Multiple outbuildings include a detached garage/workshop and a large shop

Mandy Harter RE/MAX 4000, INC

Welcome to your dream retreat on East Orchard Mesa—where luxury meets lifestyle on 3 irrigated acres surrounded by orchards and vineyards. This custom brick ranch offers privacy, panoramic views of Mt. Garfield and the Grand Mesa, and a rare in-ground pool! A grand circular driveway welcomes you to the beautifully landscaped grounds. Step inside to discover a stunning and expansive open-concept

Laura Black RE/MAX 4000, INC

Endless hobby farm potential! Tucked against 45,000 acres of BLM land, this 6.5-acre property (5 acres irrigated) is the kind of opportunity that rarely comes along in Palisade. With a charming farmhouse, irrigation infrastructure, a private head gate, packing shed, cooler, greenhouse, and detached shop already in place - the groundwork is set for a productive hobby farm, small-scale growing

Laura Black RE/MAX 4000, INC

Of the thousands of homes that sell each year in the Grand Valley, this is the one that truly stands apart. An exceptionally rare offering, this luxury estate showcases authentic Tuscany-inspired finishes, breathtaking views, and a setting that simply cannot be replicated. Homes like this are not just purchased...they are experienced. This home has it all. With a Palisade address but centrally

KENZIE ROSS COLDWELL BANKER DISTINCTIVE PROPERTIES

Experience the best of Colorado wine country at this exceptional Palisade property, where luxury, privacy, and Western charm come together in an unforgettable setting. Nestled among established vineyards just west of downtown Palisade, this custom home enjoys breathtaking views of Mount Garfield, expansive skies, and the relaxed lifestyle that makes this area so desirable. Designed for both

Alicia Doolin Coldwell Banker Distinctive Properties

Welcome to this 6.87 AC Organic farm. This is vibrant space where the rhythm of nature and sustainable living converge. Operating as a carefully planned, field to table vegetable business since 2014, the owners have crafted a space for you to enjoy self-sustained living or continue with the roadside fruit stand business and work with current providers. The property includes 5 year-round

TAMMY CRAIG BETTER HOMES AND GARDENS FRUIT & WINE

Discover your own piece of paradise in Palisade's celebrated Fruit and Wine Byway. Set on nearly two picturesque acres beneath mature shade trees, this exceptional property offers the perfect balance of rural charm, privacy, and modern convenience. The three-bedroom, three-bath home is warm and inviting, featuring an eat-in kitchen, formal dining room, dramatic living room with soaring two-story

Brian Donaldson BRAY REAL ESTATE