Homes for Sale in 63801

• 

  

  

  /27

  $279,900

  • 3 Beds
  • 2 Baths
  • 1,946 Sq Ft

  829 Plantation Blvd, Sikeston, MO 63801

  Welcome to this beautiful 3-bedroom, 2-bath home located in a desirable Sikeston neighborhood! Step inside to an inviting open floor plan that seamlessly connects to the living, dining and kitchen areas-perfect for both everyday living and entertaining. The vaulted ceilings add an airy, spacious feel, while natural light fills the home throughout. The kitchen offers great functionality and flows

  Pam Dannenmueller EDGE Realty, ERA Powered

  829 Plantation Blvd, Sikeston, MO 63801
• 

  

  

  /8

  $90,000

  • Land
  • 3 Acres
  • $30,000 per Acre

  2215 State Highway U, Sikeston, MO 63801

  Imagine a quiet country setting just a short drive to Interstate 55 with only 15 minutes to both Cape Girardeau & Sikeston. This property is not only located in Kelly School district but situated directly on a paved state road with access to county water. This cleared lot is ready for you to build your dream home on with a lot of space to stretch out and enjoy a peaceful country setting.

  Kyla Evans Paul Kitchen & Associates

  2215 State Highway U, Sikeston, MO 63801
• 

  

  /2

  $194,000

  • 2 Beds
  • 1 Bath
  • 3,300 Sq Ft

  617 Daniel St, Sikeston, MO 63801

  Great investment opportunity featuring two recently remodeled duplexes, offering a total of four 2-bedroom, 1-bath units. These properties have been updated and are ready for immediate occupancy or lease-up. Each unit is thoughtfully laid out with comfortable living spaces, making them attractive to long-term tenants. Three of the four units are currently vacant, providing flexibility for an

  Lawren McMullan EDGE Realty, ERA Powered

  617 Daniel St, Sikeston, MO 63801
• 

  

  

  /21

  $249,000 New Construction

  • 3 Beds
  • 2 Baths
  • 1,300 Sq Ft

  50 Byrd Dr, Sikeston, MO 63801

  Welcome to this stunning NEW construction home, thoughtfully designed with modern living in mind. This beautifully crafted residence features an open-concept floor plan that seamlessly connects the living, dining, and kitchen areas—perfect for both everyday living and entertaining. Offering 3 spacious bedrooms and 2 full bathrooms, the home provides comfort and functionality for a variety of

  Lawren McMullan EDGE Realty, ERA Powered

  50 Byrd Dr, Sikeston, MO 63801
• 

  

  

  /60

  $475,000

  • 4 Beds
  • 4 Baths
  • 3,833 Sq Ft

  118 Greenbriar Dr, Sikeston, MO 63801

  Located on a desirable corner lot in one of the most sought-after neighborhoods on the north end of Sikeston, this meticulously maintained custom-built home (1988) offers exceptional space, craftsmanship, and distinctive features rarely found in today’s homes. With approximately 3,800 square feet of living space, the home features 4 bedrooms and 4 bathrooms, providing plenty of room for

  Stephanie Anderson SMG Realty

  118 Greenbriar Dr, Sikeston, MO 63801
• 

  /2

  $400,000

  • Land
  • 2.63 Acres
  • $152,091 per Acre

  109 Stallcup Dr, Sikeston, MO 63801

  Over 2.5 acres of commercial property located in the heart of Sikeston's booming retail and hospitality area. Just a block from Wal-Mart Supercenter, 2 new hotels, shopping and restaurants, and a half mile to the intersection of US Highways 60 & 61. This is a premium location at an outstanding price.

  Tim Merideth Century 21 Premiere Realty

  109 Stallcup Dr, Sikeston, MO 63801
• 

  

  /34

  $215,000

  • 4 Beds
  • 2 Baths
  • 1,922 Sq Ft

  406 Lynn St, Sikeston, MO 63801

  Located in the highly sought-after Mini Farms subdivision just outside Sikeston, this beautifully remodeled 4-bedroom, 2-bath home on 1.84 acres offers the perfect combination of modern updates and country-style living with convenient access to town. The home was completely remodeled in 2025 and includes major system updates such as new gas heat and air, a new gas tankless water heater, and an

  Lynsey Perry Silverthorn Realty, LLC

  406 Lynn St, Sikeston, MO 63801
• 

  

  /27

  $149,900

  • 1 Bed
  • 1 Bath
  • 986 Sq Ft

  1300 N Main St Unit 204, Sikeston, MO 63801

  LUXURY LIVING REDEFINED at Maingate Condominiums. Experience the perfect blend of security, style, and sophistication in this rarely available one bedroom executive condo. Located in Sikeston‘s premier gated community, unit 204 has been upgraded with new flooring, light fixtures, fresh paint and kitchen upgrades to make this a turnkey lifestyle for the new owner. Step inside to an open-concept

  Reida Kimes Century 21 Premiere Realty

  1300 N Main St Unit 204, Sikeston, MO 63801
• 

  

  /43

  $325,000

  • 4 Beds
  • 3.5 Baths
  • 4,799 Sq Ft

  307 Circle Dr, Sikeston, MO 63801

  Spacious 4,000+ sq ft home with a saltwater pool on a quiet circle street in Sikeston! This well-built property offers incredible space for living, entertaining, and relaxing both inside and out. The home features large, light-filled living areas and two fireplaces, creating a warm and inviting atmosphere perfect for everyday living or hosting family and friends. A standout feature of this

  Stephanie Anderson SMG Realty

  307 Circle Dr, Sikeston, MO 63801
• 

  

  /11

  $99,900

  • 3 Beds
  • 1 Bath
  • 1,237 Sq Ft

  303 Greer Ave, Sikeston, MO 63801

  Are you ready for a small home in Sikeston? You can sit on the covered, front porch and enjoy a morning cup of coffee while watching others out and about! This Bungalow-style home boasts of 3 bedrooms, 1 bathroom, an eat-in kitchen, a covered carport in back yard all located on a corner lot. The kitchen has several cabinets, an island along the wall, and a range and a dishwasher included. It's

  Scott Harrison Delta Realty, LLC

  303 Greer Ave, Sikeston, MO 63801
• 

  

  /19

  $189,000

  • 4 Beds
  • 2 Baths
  • 1,914 Sq Ft

  410 Hux St, Sikeston, MO 63801

  Discover your dream home in this delightful 4-bedroom, 2-bath ranch that perfectly blends comfort and style. Nestled on a serene street, this inviting residence features a spacious front porch, ideal for sipping morning coffee or enjoying evening sunsets. Step inside to find a bright and airy layout that welcomes you with warmth and charm.The heart of the home boasts an open living area,

  Brandon Kielhofner EPM Real Estate

  410 Hux St, Sikeston, MO 63801
• 

  

  /12

  $237,000

  • 2,262 Sq Ft

  203 N Kingshighway St Unit A & B, Sikeston, MO 63801

  Lisa Russell EXP Realty LLC

  203 N Kingshighway St Unit A & B, Sikeston, MO 63801
• 

  

  /12

  $139,000

  • 3 Beds
  • 1 Bath
  • 1,080 Sq Ft

  2012 Kentucky St, Sikeston, MO 63801

  Charming 3 bedroom, 1 bathroom home featuring warm and inviting living spaces. Recent updates include an updated bathroom, freshly painted kitchen cabinets, and exterior paint improvements that add to the home’s curb appeal. This property offers comfortable living and great potential, making it a perfect option for first-time home buyers, those looking to downsize, or investors seeking an

  Rebecca Ault EDGE Realty, ERA Powered

  2012 Kentucky St, Sikeston, MO 63801
• 

  

  /17

  $255,000

  • 4 Beds
  • 2 Baths
  • 2,347 Sq Ft

  209 Aletha Dr, Sikeston, MO 63801

  Looking for a home outside the city limits in a great neighborhood? This property offers the space, yard, and location you’ve been looking for. This 4 bedroom, 2 bathroom home has been recently remodeled and features several major updates including a newer roof, new hot water heater, new septic system, updated kitchen. The home offers an open concept layout between the living area and kitchen,

  Hudson Kuykendall EDGE Realty ERA Powered

  209 Aletha Dr, Sikeston, MO 63801
• 

  

  /9

  $32,000

  • 2 Beds
  • 1 Bath
  • 1,116 Sq Ft

  405 Branum St, Sikeston, MO 63801

  Investor Special in Sikeston! Opportunity awaits at 405 Branum St. This property has been partially gutted and is ready for your vision to bring it back to life. Major demo work has already been completed, saving you time and upfront labor. Whether you’re looking for your next fix-and-flip project, rental property, or long-term hold, this is a blank canvas with serious upside potential.

  Jonathan Adams Keller Williams Realty West

  405 Branum St, Sikeston, MO 63801
• 

  

  /9

  $100,000

  • 2 Beds
  • 1 Bath
  • 1,030 Sq Ft

  448 Crowe St, Sikeston, MO 63801

  TWO BEDROOM HOUSE LOCATED ON A LARGE CORNER LOT WITH 3 EXTRA VACANT LOTS INCLUDED, ALONG WITH TWO DETACHED SHOPS

  Tony McDonald McDonald Realty

  448 Crowe St, Sikeston, MO 63801
• 

  

  /22

  $275,000

  • 3 Beds
  • 2 Baths
  • 2,147 Sq Ft

  2011 State Highway H, Sikeston, MO 63801

  This one checks a LOT of boxes!3 beds. 2 baths. Kelly School District. Updated kitchen. Finished basement with a full bath. Big backyard. 2-car garage.And yes — the expensive stuff is already done. We're talking a recently remodeled basement and updated kitchen that actually makes you want to cook in it. No big projects waiting for you on move-in day. Just a solid, move-in ready home in

  Amber Prasanphanich EDGE Realty ERA Powered

  2011 State Highway H, Sikeston, MO 63801
• 

  

  /20

  $172,900

  • 3 Beds
  • 2 Baths
  • 1,382 Sq Ft

  10 Dement Rd, Sikeston, MO 63801

  This 3 bedroom, 1 & 3/4 bath home features a split bedroom floor plan and an eat-in kitchen, with a two car garage. Outside features an RV electrical hookup with parking, a nice rear patio, large yard, a shed and a kennel. If you area looking for space, check this one out. It is just out of town in Ridgeview Acres with friendly neighbors and feels like country living. The backyard is large enough

  allen basham EXP Realty, LLC

  10 Dement Rd, Sikeston, MO 63801
• 

  

  /11

  $127,500

  • 2 Beds
  • 1 Bath
  • 910 Sq Ft

  628 Moore Ave, Sikeston, MO 63801

  This charming bungalow in Sikeston's historic district has been beautifully updated and is ready for its new owner. Featuring 2 bedrooms and 1 bath, it's the perfect home for first-time buyers or anyone looking to downsize. Conveniently located withing walking distance to the YMCA and local grocery stores, this home offers both everyday convenience and timeless charm.

  Rene Church Century 21 Premiere Realty

  628 Moore Ave, Sikeston, MO 63801
• 

  

  /53

  $560,000

  • 4 Beds
  • 3 Baths
  • 3,770 Sq Ft

  106 Jennings Ln, Sikeston, MO 63801

  Experience elevated living in this beautifully crafted 3,770-square-foot residence ideally located just minutes from the conveniences of Sikeston. Offering four bedrooms and three full baths, this home was designed for both impressive entertaining and effortless daily living.The open-concept design creates a seamless flow between the living room, dining space, and chef-inspired kitchen. A

  Karen Chamberlain Poplar Bluff Realty Inc

  106 Jennings Ln, Sikeston, MO 63801
• 

  

  /4

  $15,000

  • Land
  • 0.16 Acre
  • $93,750 per Acre

  315 Jackson St, Sikeston, MO 63801

  Vacant residential lot ready for a buyer to build on. This is a 70 x 100 corner lot.

  Annie Harris Century 21 Premiere Realty

  315 Jackson St, Sikeston, MO 63801
• 

  

  /11

  $169,900

  • 4 Beds
  • 2 Baths
  • 2,101 Sq Ft

  502 Jaycee St, Sikeston, MO 63801

  This well-maintained four-bedroom, two-bath home offers plenty of room to grow, plus a versatile bonus space that can serve as a fifth bedroom, home office, playroom, or anything you envision. Situated on a desirable corner lot, the property features a fully fenced backyard—perfect for pets, gardening, or outdoor entertaining. Step inside to a warm and inviting layout, beginning with an eat-in

  Scott Harrison Delta Realty, LLC

  502 Jaycee St, Sikeston, MO 63801
• 

  

  /12

  $195,000

  • 3 Beds
  • 2 Baths
  • 1,421 Sq Ft

  112 N 6th St, Sikeston, MO 63801

  Step inside to find a bright and airy living space featuring a freshly painted interior and brand-new flooring throughout. The heart of the home is the spacious, open-concept kitchen—perfect for entertaining—boasting ample cabinetry and a layout that flows seamlessly into the dining and living areas. Both bathrooms have been updated, ensuring this home is move-in ready from day one.Situated

  Kaci Self Epique Realty

  112 N 6th St, Sikeston, MO 63801
• 

  

  /4

  $200,000

  • Land
  • 18.5 Acres
  • $10,811 per Acre

  2093 E County Highway 450, Sikeston, MO 63801

  Discover the perfect blend of open space and natural beauty with this 18.5-acre tract offering a variety of potential uses. Featuring a mix of wooded areas and open ground, this property is ideal for building your dream home, creating a private retreat, or investing for the future. Abundant wildlife—including deer and turkey—makes this a great spot for nature lovers or recreational use. Multiple

  Tara Newell-Koehler Century 21 Ashland Realty

  2093 E County Highway 450, Sikeston, MO 63801
• 

  

  /13

  $171,000

  • Land
  • 14 Acres
  • $12,214 per Acre

  000 Heathercrest St, Rootwad Township, MO 63801

  14 +/- acres of row-crop farmland with development potential located just outside Sikeston, Missouri. Property includes approximately 14 acres of tillable cropland plus 9 platted building lots. Ideal for farmland investors, developers, or buyers seeking agricultural income, residential development, or long-term land investment. Level, open ground with easy access to Sikeston, highways, and local

  Geoffrey Myers Living The Dream Inc.

  000 Heathercrest St, Rootwad Township, MO 63801
• 

  

  /17

  $380,000

  • Land
  • 38 Acres
  • $10,000 per Acre

  00 Ellen Ave, Sikeston, MO 63801

  38 +/- acres of row-crop farmland with development potential located just outside Sikeston, Missouri. Property includes approximately 38 acres of tillable cropland plus 39 platted building lots in. Ideal for farmland investors, developers, or buyers seeking agricultural income, residential development, or long-term land investment. Level, open ground with easy access to Sikeston, highways, and

  Geoffrey Myers Living The Dream Inc.

  00 Ellen Ave, Sikeston, MO 63801
• 

  

  /16

  $205,000

  • 3 Beds
  • 2 Baths
  • 1,200 Sq Ft

  2163 E County Highway 450, Sikeston, MO 63801

  Welcome to this beautifully maintained one-owner home, thoughtfully designed and built with comfort in mind. Offering 3 bedrooms, 2 bathrooms, and approximately 1,200 sq ft of living space, this property blends an open, inviting layout with the peaceful feel of country living. Step inside to an open concept living room and kitchen, perfect for entertaining, family gatherings, or simply enjoying

  Christy Lawrence C. Lawrence Realty LLC

  2163 E County Highway 450, Sikeston, MO 63801
• 

  

  /38

  $315,000

  • 3 Beds
  • 2 Baths
  • 2,495 Sq Ft

  202 N Brushwick Ave, Sikeston, MO 63801

  Welcome home to this stunning single-level retreat on a huge lot, offering the perfect blend of space, comfort, and style. Step inside to a large open-concept floor plan filled with natural light from dramatic floor-to-ceiling windows, creating an airy, inviting atmosphere ideal for both everyday living and entertaining.The warm and inviting den features beautiful wood paneling, adding

  Lawren McMullan EDGE Realty, ERA Powered

  202 N Brushwick Ave, Sikeston, MO 63801
• 

  

  /28

  $249,900

  • 3 Beds
  • 1.5 Baths
  • 1,782 Sq Ft

  109 Lynn St, Sikeston, MO 63801

  Welcome to 109 Lynn St. in Sikeston, located in the desirable Mini Farms subdivision - where space and comfort come together for family living. This 3-bedroom, 2-bathroom home offers two spacious living rooms, perfect for family movie nights, play areas, or hosting friends and relatives. Sitting on 1.62 acres, there is plenty of room for kids to play, pets to roam, and outdoor gatherings to

  Lauren DeWitt EDGE Realty, ERA Powered

  109 Lynn St, Sikeston, MO 63801
• 

  

  /36

  $260,000

  • 3 Beds
  • 3 Baths
  • 1,492 Sq Ft

  119 Depro Ave, Sikeston, MO 63801

  Newly remodeled and move-in ready just outside Sikeston! Sitting on a spacious corner lot with 0.7187 acres, this home gives you room to breathe and room to work. You’ll love the outdoor setup with a large shed plus a brand-new 30x40 pole barn, perfect for hobbies, storage, or a workshop. New roof, fresh updates, and space inside and out—this one checks all the boxes!

  Jessica Moore EXP Realty, LLC

  119 Depro Ave, Sikeston, MO 63801
• 

  

  /21

  $265,000

  • 3 Beds
  • 2.5 Baths
  • 1,774 Sq Ft

  1811 State Highway Z, Sikeston, MO 63801

  This 3 bedroom, 2.5 bath home offers the perfect blend of space, privacy, and convenience. Situated on just over an acre +/- outside of city limits, you can enjoy peaceful country living while still being less than a 10 minute drive to town. The spacious layout provides comfortable living with thoughtful updates throughout. A standout feature is the shop, which offers over a thousand square feet

  Rachel Sitzes Poplar Bluff Realty Inc

  1811 State Highway Z, Sikeston, MO 63801
• 

  

  /17

  $37,900

  • 2 Beds
  • 1 Bath
  • 728 Sq Ft

  309 Benton St, Sikeston, MO 63801

  Charming 2-bedroom, 1-bath home with great potential. A warm and welcoming layout offers the perfect canvas for your personal touches. Make it your own and enjoy the possibilities!

  Mike Zouglas REO Xpress, LLC

  309 Benton St, Sikeston, MO 63801
• 

  

  /32

  $149,900

  • 3 Beds
  • 2 Baths
  • 1,250 Sq Ft

  219 Petroleum St, Sikeston, MO 63801

  Take a look at this nice, clean, move-in ready home sporting a NEW ROOF! The charming front porch leads to an open living, kitchen & dining area. Primary bedroom with 3/4 bath, two additional bedrooms, one full bath and a one car attached carport, a 12x24 storage shed with walk-in door and garage door. This is the perfect size for a starter home or someone ready to downsize. Come and see for

  Rebecca Shaver C. Lawrence Realty LLC

  219 Petroleum St, Sikeston, MO 63801
• 

  

  /14

  $119,000

  • 3 Beds
  • 1 Bath
  • 1,080 Sq Ft

  318 Kendall St, Sikeston, MO 63801

  Welcome home to this fully remodeled 3-bedroom, 1-bath charmer, offering modern comfort and timeless style. Every detail has been thoughtfully updated, including fresh flooring, contemporary fixtures, new paint, and an inviting open layout that maximizes both light and space. All three bedrooms are generously sized, providing flexibility for family, guests, or a home office. The updated bathroom

  Lawren McMullan EDGE Realty, ERA Powered

  318 Kendall St, Sikeston, MO 63801
• 

  

  /72

  $665,000

  • 4 Beds
  • 4 Baths
  • 4,924 Sq Ft

  1304 Primrose Dr, Sikeston, MO 63801

  Built in 2019, this beautiful 4-bedroom, 4-bathroom home sits in one of Sikeston’s most desirable neighborhoods and offers a great mix of comfort, style, and modern features.You’ll love the brick-and-stone exterior and the inviting main-level living room with a cozy gas fireplace. Two bedrooms are located on the main floor, with two more upstairs—perfect for guests, kids, or a home office

  Lauren DeWitt EDGE Realty, ERA Powered

  1304 Primrose Dr, Sikeston, MO 63801
• 

  /2

  $8,500

  • Land
  • 0.17 Acre
  • $51,082 per Acre

  Lot 6 Fisher Dr, Morehouse, MO 63868

  Nice corner lot located at the intersection of Fisher Drive and Spruce Street in Morehouse, Missouri. This level lot offers excellent access and visibility and would make a great home site or investment property. City utilities are available nearby (buyer to verify). Convenient location within a quiet residential area, just a short drive to Sikeston and area amenities.

  Stephanie Anderson SMG Realty

  Lot 6 Fisher Dr, Morehouse, MO 63868
• 

  

  /12

  $264,000

  • 3 Beds
  • 2 Baths
  • 1,965 Sq Ft

  402 Garner St, Sikeston, MO 63801

  FIRST TIME ON THE MARKET !CUSTOM BUILT, ONE OWNER HOME, OPEN FLOOR PLAN WITH CUSTOM CABINETS, FLOORING , HUGE WALK IN SHOWER, INCLOSED SUNROOM ,ALL SITTING ON A LARGE CORNER LOT IN THE WESTVIEW SUBDIVISION AND SIKESTON SCHOOL DISTRICT .

  Tony McDonald McDonald Realty

  402 Garner St, Sikeston, MO 63801
• 

  

  /7

  $169,900

  • 3 Beds
  • 1.5 Baths
  • 1,653 Sq Ft

  926 Crescent Dr, Sikeston, MO 63801

  This beautifully maintained all-brick hoe is nestled in a quiet, family-friendly neighborhood. It features 3 bedrooms, 1.5 baths, and a full basement with the potential for an additional bathroom. The interior boasts new laminate flooring throughout, and the roof was replaced in 2020, and the HVAC is 2 years old. Enjoy a spacious kitchen, with a double oven - perfect for cooking and entertaining

  Rene Church Century 21 Premiere Realty

  926 Crescent Dr, Sikeston, MO 63801
• 

  

  /22

  $77,000

  • Land
  • 3 Acres
  • $25,667 per Acre

  Lot 5 County Highway 401, Benton, MO 63736

  Discover the perfect blend of country charm and modern convenience in Legacy Lake Estates, located just off County Highway 401 in Benton, MO. Phase 1 offers 14 spacious 3-acre lots, each thoughtfully designed to provide privacy, tranquility, and direct views and access to a beautiful lake. Enjoy the peace of rural living while being just minutes from Interstate 55, ideally situated between Cape

  Lauren DeWitt EDGE Realty, ERA Powered

  Lot 5 County Highway 401, Benton, MO 63736
• 

  

  /22

  $77,000

  • Land
  • 3 Acres
  • $25,667 per Acre

  Lot 12 County Highway 401, Benton, MO 63736

  Discover the perfect blend of country charm and modern convenience in Legacy Lake Estates, located just off County Highway 401 in Benton, MO. Phase 1 offers 14 spacious 3-acre lots, each thoughtfully designed to provide privacy, tranquility, and direct views and access to a beautiful lake. Enjoy the peace of rural living while being just minutes from Interstate 55, ideally situated between Cape

  Lauren DeWitt EDGE Realty, ERA Powered

  Lot 12 County Highway 401, Benton, MO 63736

Showing Results 1 - 40, Page 1 of 4