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South San Francisco, CA Homes for Rent

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  • /74

    Starting at $4,160 Per Month

    • 2 Beds

    842-858 Antoinette Ln, South San Francisco, CA 94080

    Peninsula Pines Apartments offers beautiful, newly remodeled apartments featuring: gas fireplaces, upgraded kitchens, berber-style carpeting, modern lighting, and friendly staff and maintenance. Please call for an appointment today!

    Peninsula Pines Apartments

    842-858 Antoinette Ln, South San Francisco, CA 94080
  • /24

    Starting at $3,500

    Total Monthly Price

    • Studio - 2 Beds

    2 Pacific Bay Cir, San Bruno, CA 94066

    Live at Pacific Bay Vistas in San Bruno, California and enjoy our community that is smoke free with incredible views of the San Francisco Bay and the Pacific Ocean. Your time matters, so we skip the hidden fee shuffle. Our prices include required monthly costs, no extra math, no mystery, just the real number. Our apartment homes feature open layouts, a private patio or balcony, walk in closets,

    Pacific Bay Vistas

    2 Pacific Bay Cir, San Bruno, CA 94066
  • /40

    Starting at $2,795 Per Month

    • 1 - 2 Beds

    849 W Orange Ave, South San Francisco, CA 94080

    Enjoy the perfect mix of relaxation and convenience creating an ideal place for you to call your new home. Choose from one of our spacious 1 and 2 bedroom floorplans - many with beautifully appointed kitchens featuring stainless steel appliances, oversized closets, and private patios where you can enjoy stunning views of the courtyard and relax after a busy day.Spend your downtime

    Clubview Apartment Homes

    849 W Orange Ave, South San Francisco, CA 94080
  • /15

    Starting at $2,450 Per Month

    • 1 Bed

    362 Alida Way, South San Francisco, CA 94080

    NO UNITS AVAILABLE AT THIS TIME ! Enjoy the Bay Area's abundant beauty and exciting activities from your home in the center of it all. Alida Way Apartments is conveniently located in the tranquil Avalon neighborhood of South San Francisco and offers spacious garden residences with well designed floor plans and private balconies. Each apartment features a private garage with ample storage

    362 Alida Way, South San Francisco, CA 94080
  • /40

    Starting at $4,298 Per Month

    • Studio - 2 Beds

    150 Airport Blvd, South San Francisco, CA 94080

    Conveniently located within blocks of South San Francisco's historic downtown, Altitude Apartments offers the comfort of a residential neighborhood while still being close to a vibrant downtown scene. Altitude Apartments encompass contemporary style with a sophisticated San Franciscan sensibility. Our spacious studio, 1, and 2 bedroom homes are meticulously outfitted with?high-end, modern

    Altitude Apartments

    150 Airport Blvd, South San Francisco, CA 94080
  • /34

    Starting at $3,600 Per Month

    • Studio - 3 Beds

    401 Cypress Ave, South San Francisco, CA 94080

    Welcome to a more polished way to live in South San Francisco. At Bell South City, you're at the center of the South City lifestyle, surrounded by the energy of the biotech corridor, the convenience of Caltrain, and everyday comfort in our community designed for modern living. Our walkable luxury apartments place you near Oyster Point, top biotech employers like Genentech, Amgen, and Verily, and

    Bell South City

    401 Cypress Ave, South San Francisco, CA 94080
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    Starting at $3,224

    Total Monthly Price

    • 1 - 3 Beds

    3880 Callan Blvd, South San Francisco, CA 94080

    Unpack and relax in one of our light and bright one, two or three bedroom apartment homes which were designed with ample closet space and comfort in mind. If working out is your passion, our fitness center is the place for you or if you're looking for relaxation, our picnic area complete with barbeques will be the ideal hang out. Our community is complete with a recreation room and a playground

    Skyline View

    3880 Callan Blvd, South San Francisco, CA 94080
  • /20

    $4,220

    Total Monthly Price

    • 3 Beds
    • 2 Baths
    • 1,100 Sq Ft
    • House for Rent

    657 Grand Ave, South San Francisco, CA 94080

    Feel at home wherever you choose to live with Blueground. You’ll love this lovely Downtown furnished three bedroom house with its modern decor, fully equipped kitchen, and exquisite living room. Ideally located, you’re close to all the best that South San Francisco has to offer! (ID #SFO1655) The advertised rate of $4,220/month is the lowest available price, based on a 1 month(s) and 29

    657 Grand Ave, South San Francisco, CA 94080
  • /28

    $8,950

    Total Monthly Price

    • 3 Beds
    • 2 Baths
    • 1,820 Sq Ft
    • Condo for Rent

    460 Valverde Dr, South San Francisco, CA 94080

    Welcome to this beautifully renovated single-family home located at the corner of Avalon Drive and Mariposa Drive in the desirable South San Francisco neighborhood. Offering 1,820 square feet of updated living space on a 5,768-square-foot lot, this fully furnished residence features modern finishes, smart home technology, and a thoughtfully designed floor plan for comfortable everyday living.

    460 Valverde Dr, South San Francisco, CA 94080
  • /13

    $4,000

    Total Monthly Price

    • 2 Beds
    • 1 Bath
    • 1,200 Sq Ft
    • House for Rent

    215 Hazelwood Dr, South San Francisco, CA 94080

    Welcome to our charming and exceptionally spacious 2-bedroom, 1-bathroom single-family home. Thoughtfully designed with a bright, open flow, our home offers comfort, privacy, and classic appeal.Generous Layout: Sunlit, open living and dining areas perfect for relaxing or entertaining. A wooden deck for outside grilling or stargazing chilling. Energy Efficient: Brand new double-pane

    215 Hazelwood Dr, South San Francisco, CA 94080
  • /8

    $7,470

    Total Monthly Price

    • 1 Bed
    • 1 Bath
    • 667 Sq Ft
    • Condo for Rent

    401 Cypress Ave Unit SI FL6-ID1070892P, South San Francisco, CA 94080

    The advertised rate of $7,471/month is the lowest available price, based on a 1 month(s) stay with a move-in date of April 1, 2028. Rates vary depending on the duration of stay, season, and other parameters. For exact pricing and additional pricing components, please visit our website and enter your desired move-in and move-out dates. The rate is applicable when billed upfront; it can be

    401 Cypress Ave Unit SI FL6-ID1070892P, South San Francisco, CA 94080
  • /8

    $7,470

    Total Monthly Price

    • 1 Bed
    • 1 Bath
    • 753 Sq Ft
    • Condo for Rent

    401 Cypress Ave Unit SI FL5-ID1280670P, South San Francisco, CA 94080

    The advertised rate of $7,471/month is the lowest available price, based on a 1 month(s) stay with a move-in date of April 1, 2028. Rates vary depending on the duration of stay, season, and other parameters. For exact pricing and additional pricing components, please visit our website and enter your desired move-in and move-out dates. The rate is applicable when billed upfront; it can be

    401 Cypress Ave Unit SI FL5-ID1280670P, South San Francisco, CA 94080
  • /8

    $8,384

    Total Monthly Price

    • 2 Beds
    • 1 Bath
    • 850 Sq Ft
    • Condo for Rent

    401 Cypress Ave Unit SI FL5-ID1280669P, South San Francisco, CA 94080

    The advertised rate of $8,385/month is the lowest available price, based on a 1 month(s) stay with a move-in date of April 1, 2028. Rates vary depending on the duration of stay, season, and other parameters. For exact pricing and additional pricing components, please visit our website and enter your desired move-in and move-out dates. The rate is applicable when billed upfront; it can be

    401 Cypress Ave Unit SI FL5-ID1280669P, South San Francisco, CA 94080
  • /11

    $5,100 Per Month

    • 3 Beds
    • 2 Baths
    • 1,322 Sq Ft
    • House for Rent

    823 Linden Ave, South San Francisco, CA 94080

    Welcome home to 823 Linden, a charming and light-filled 3 bed 2 bath home with timeless character throughout! Enjoy the inviting and spacious eat-in kitchen, separate dining room, primary suite, attached garage, washer and dryer in the home and a large low-maintenance backyard. The location offers everyday convenience being walking distance to vibrant downtown South San Francisco's local shops

    823 Linden Ave, South San Francisco, CA 94080
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    $7,470

    Total Monthly Price

    • 1 Bed
    • 1 Bath
    • 678 Sq Ft
    • Condo for Rent

    401 Cypress Ave Unit SI FL5-ID1064994P, South San Francisco, CA 94080

    The advertised rate of $7,471/month is the lowest available price, based on a 1 month(s) stay with a move-in date of April 1, 2028. Rates vary depending on the duration of stay, season, and other parameters. For exact pricing and additional pricing components, please visit our website and enter your desired move-in and move-out dates. The rate is applicable when billed upfront; it can be

    401 Cypress Ave Unit SI FL5-ID1064994P, South San Francisco, CA 94080
  • /27

    $5,495 Per Month

    • 3 Beds
    • 2 Baths
    • 1,410 Sq Ft
    • House for Rent

    1225 Douglas Way, South San Francisco, CA 94080

    To view a virtual tour and schedule a showing directly, please visit our website www. kennyrealty .comClick to view virtual tour: This beautifully remodeled 3 bedroom, 2 bathroom home in South San Francisco's sought-after Sunshine Gardens neighborhood is ready for its next chapter. Every detail has been thoughtfully updated, from the brand new kitchen with stainless steel appliances

    1225 Douglas Way, South San Francisco, CA 94080
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    $5,750 Per Month

    • 3 Beds
    • 2 Baths
    • House for Rent

    136 Rosewood Way, South San Francisco, CA 94080

    To view a virtual tour and schedule a showing directly, please visit our website www. kennyrealty .comClick to view virtual tour: Tucked into the highly desirable Brentwood neighborhood — directly across from Brentwood Park's basketball and tennis courts, playground, and tree-lined walking paths — this 3 bedroom, 2 bathroom home offers space, light, and flexibility that's hard to

    136 Rosewood Way, South San Francisco, CA 94080
  • /33

    $5,600 Per Month

    • 3 Beds
    • 2 Baths
    • 1,100 Sq Ft
    • Townhouse for Rent

    663 1st Ln, South San Francisco, CA 94080

    (1 MIDSIZE GARAGE PARKING AVAILABLE) Pet-friendly 3BR/2BA upper-level duplex near downtown South San Francisco. Bright, modern home with balcony, full kitchen, and easy access to Kaiser, Stanford, and the biotech hub ideal for extended stays and traveling professionals. Address: 663 1st Ln, South San Francisco, CA Experience modern comfort in this pet-friendly 3-bedroom, 2-bath

    663 1st Ln, South San Francisco, CA 94080
  • /8

    $8,664

    Total Monthly Price

    • 2 Beds
    • 1 Bath
    • 882 Sq Ft
    • Condo for Rent

    401 Cypress Ave Unit SI FL8-ID1280658P, South San Francisco, CA 94080

    The advertised rate of $8,664/month is the lowest available price, based on a 30 day(s) stay with a move-in date of March 1, 2028. Rates vary depending on the duration of stay, season, and other parameters. For exact pricing and additional pricing components, please visit our website and enter your desired move-in and move-out dates. The rate is applicable when billed upfront; it can be

    401 Cypress Ave Unit SI FL8-ID1280658P, South San Francisco, CA 94080
  • /18

    $2,695 Per Month

    • 1 Bed
    • 1 Bath
    • Condo for Rent

    517 1st Ln Unit 519 1st Lane - MBA02-03 - 109 - VACANT, South San Francisco, CA 94080

    To view a virtual tour and schedule a showing directly, please visit our website www. kennyrealty .com Click to view virtual tour: Welcome home to this updated 1 bedroom, 1 bathroom, one unit of a duplex at 519 1st Lane in South San Francisco. New carpet runs throughout the home, giving the space a fresh, clean feel from room to room.The updated kitchen offers a bright, functional

    517 1st Ln Unit 519 1st Lane - MBA02-03 - 109 - VACANT, South San Francisco, CA 94080

Why Live in South San Francisco

South San Francisco, California, is a dense suburb on the San Francisco Peninsula known for its midcentury homes, landscaped lawns, and cozy downtown district. The city, which skirts the edge of San Bruno Mountain and the San Francisco Bay, is home to major biotech companies like Genentech, Amgen, and Exelixis, earning it the title "the birthplace of biotechnology." This industry has significantly boosted local real estate values and funded improvements to parks and city amenities. Housing options range from historic early 20th-century dwellings to contemporary homes, with many post-war ranch homes and split-levels in neighborhoods such as Sunshine Gardens, Westborough, and Serra Highlands. Downtown South San Francisco features historic single-story shops and storefronts, including family-owned businesses and eclectic dining options. Residents enjoy outdoor attractions like hiking trails on Sign Hill and San Bruno Mountain, as well as the San Francisco Bay Trail. The South San Francisco Unified School District is highly rated, with El Camino High boasting a graduation rate of 96% and strong academic scores. The city is conveniently located 10 miles from Downtown San Francisco and 25 miles from Silicon Valley, with access to BART, Caltrain, and San Francisco International Airport.

Frequently Asked Questions

How much does it cost to rent a home in South San Francisco, CA?
The median rent for a home in South San Francisco, CA is $6,610 per month, though prices vary by neighborhood, size, and property type. As of September 2026, condos tend to be the most affordable option while single-family homes and townhouses are currently more expensive.
How much do you need to make to afford rent in South San Francisco, CA?
To comfortably afford the median rent in South San Francisco, CA, a household needs to earn roughly $264,400 per year. This is based on the common guideline that households should spend no more than 30% of gross income on housing. Most landlords require monthly household income of at least 3x the monthly rent, and with a median rent of $6,610 per month in South San Francisco, CA, renters typically need to show $19,830 per month in gross income to qualify. Actual affordability will vary depending on household debts, other living expenses, and overall budget.
Is it more affordable to rent or buy in South San Francisco, CA?
In South San Francisco, CA, the price-to-rent ratio is 15.8, which generally favors renting. This ratio divides the median home price by the annual median rent: below 15 typically favors buying, 15 to 20 is balanced, and above 20 typically favors renting. Your finances, how long you plan to stay, and costs like mortgage rates, taxes, and maintenance all factor into the decision.
What neighborhoods in South San Francisco, CA are best for renting a home?
The best neighborhood for renting in South San Francisco, CA depends on your priorities: commute, walkability, budget, and lifestyle all play a role. Popular areas for renting a home include Central Brisbane, Serramonte, Hillside, Sharp Park and Downtown South San Francis, each with its own character and price range.

Rental Home Trends

Number of Homes for Rent
20
Median Rent
$6,610
Median Single Family Home Rent
$5,000
Median Townhouse Rent
$5,600
Median Condo Rent
$3,800
How to Rent a Home