Defiance, MO Homes for Sale with Acreage

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  $800,000

  • 4 Beds
  • 4 Baths
  • 4,534 Sq Ft

  2503 Highway F, Defiance, MO 63341

  A Truly Unique Property Offering Peace, Privacy, & Endless Possibilities! This property has 8+/- acres that is nestled in the heart of nature & a rare find. The expansive 1500+sf original home has been thoughtfully expanded by the current homeowners w/ a 2100+sf addition to create a retreat w/ modern comforts. Over 4,700sf of living space, including a large primary suite w/ private balcony on the

  

  Ann Rothweil

  Realty Executives Premiere

  (636) 837-0123

  2503 Highway F, Defiance, MO 63341
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  Explore Defiance

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  /49

  $1,299,500

  • 4 Beds
  • 4.5 Baths
  • 4,870 Sq Ft

  14 Callaway Ridge Ct, Defiance, MO 63341

  Looking for a home that you never need to vacation from.....then this is the one! This stunning custom ranch offers over 4,800 sqft of spacious finished living space with 10 foot ceilings on the main level and 9 foot in the lower level. Natural light abounds throughout the main living area offering scenic views, wood burning fireplace that flows into the chef's gourmet kitchen complete with range

  Jakob Popp Legacy Realty Group

  14 Callaway Ridge Ct, Defiance, MO 63341
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  $799,000

  • 4 Beds
  • 2.5 Baths
  • 3,834 Sq Ft

  3751 Forest Meadow Dr, Defiance, MO 63341

  Encounter country living on 3 acres in a quiet neighborhood just a quick 10–15 min drive to your major highways & shopping/dining amenities. Directly located in the middle of wine country & a top rated school district! The expansive backyard is a great oasis ready for all of your entertainment & gardening needs! Enjoy a peaceful morning on your large covered deck (approx. 16’ x 40’) w/ vaulted

  Zach Halloran Magnolia Real Estate

  3751 Forest Meadow Dr, Defiance, MO 63341
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  $850,000

  • 4 Beds
  • 3.5 Baths
  • 3,341 Sq Ft

  19 Jacks Cabin Dr, Defiance, MO 63341

  Meticulously maintained 2-story traditional home with over 3,300 sf of finished living space and impressive landscape. Boasting 4 beds, 3.5 baths plus an office or nursery, sunroom and breakfast room. Entertain in style with a formal dining room. The chef's kitchen is a standout: plantation shutters, custom hickory cabinets, granite counters, center island, planning desk, and a double oven

  Julie Burt Blondin Group, Inc

  19 Jacks Cabin Dr, Defiance, MO 63341
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  $895,000

  • 5 Beds
  • 4.5 Baths
  • 4,852 Sq Ft

  809 Star Ridge Ct, Defiance, MO 63341

  That’s a stunning property! A Well Planned and Designed 1.5 Story Home on over Three premium, level acres, in a quiet cul-de-sac. 809 Star Ridge Court in Defiance, MO offers a luxurious blend of space, privacy, and charm. Here are some standout features: Over 4800sq. ft. of Living Space, that includes 5 Rooms, 5 Bathrooms / All New Septic System and New Roof - 2025 / Custom Millwork and

  Kevin McCarty Coldwell Banker Realty - Gundaker

  809 Star Ridge Ct, Defiance, MO 63341
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  $800,000

  • 5 Beds
  • 3.5 Baths
  • 3,846 Sq Ft

  3940 Indian Ridge Ln, Defiance, MO 63341

  Tucked away on a wooded 3.5-acre lot in scenic Defiance, this beautifully crafted atrium ranch offers over 3,800 sq ft of living space with updates, privacy, and charm. Located in Missouri Wine Country, you're just minutes from top wineries, the Katy Trail, and all the amenities of nearby towns. The main level features hardwood floors, vaulted ceilings, and large windows in the living room that

  Ashley Brickle Berkshire Hathaway HomeServices Select Properties

  3940 Indian Ridge Ln, Defiance, MO 63341
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  $1,150,000

  • 5 Beds
  • 6.5 Baths
  • 6,687 Sq Ft

  848 Golden Meadows Dr, Defiance, MO 63341

  Stunning, custom built home in Defiance on 3.64 level acres. This 1.5 sty includes TWO primary suites. Main floor 1100 SF primary suite w/ fireplace, walk-in designer closet, coffee/wine bar & direct access to the basement. Primary bath w/ a walk-in shower & double vanity sinks. Great Room features cathedral ceilings and Palladian windows. Kitchen includes 42" white cabinets, granite

  Megan Kaup SCHNEIDER Real Estate

  848 Golden Meadows Dr, Defiance, MO 63341
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  $800,000

  • 3 Beds
  • 4 Baths
  • 4,065 Sq Ft

  140 Norfork Ct, Defiance, MO 63341

  Experience refined living in this exceptional reverse 1.5-story estate nestled in Defiance, within the highly acclaimed Francis Howell Schools. Thoughtfully designed for both elegance & comfort, this residence showcases timeless travertine in the grand foyer & gleaming hardwood floors that flow through a sun-drenched living & dining space with soaring ceilings & a wood-burning fireplace, all

  Jeremy Barrett Keller Williams Realty West

  140 Norfork Ct, Defiance, MO 63341
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  $800,000

  • 3 Beds
  • 3.5 Baths
  • 5,016 Sq Ft

  3840 Rooster Ridge Ln, Defiance, MO 63341

  LOCATION is perfection! Travel down a paved road and arrive at your custom ranch home, with double garages, a finished basement, stunning seller/builder details with over 5,000 total finished SF! I'd need way more space here to describe all of the features. Large kitchen with second dining / living area arranged around the Buck stove fireplace. Brazilian cherry flooring, double wall ovens, long

  Hope Fick Blondin Group, Inc

  3840 Rooster Ridge Ln, Defiance, MO 63341
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  $1,299,000

  • 3 Beds
  • 5 Baths
  • 2,436 Sq Ft

  4075 Highway D, Defiance, MO 63341

  More details to come. This is a must see!!! This beautifully updated, well maintained home with 3 beds, (3) full (2) 1/2 baths is on 10 flat acres. Primary bedroom has a bay window, separate shower/jacuzzi tub. Family room has a wood burning fireplace. Relax 0on the covered porch that overlooks a water feature and the lake. Kitchen has granite countertops, propane cooktop, double ovens. double

  John Shaw Tom Shaw, REALTORS

  4075 Highway D, Defiance, MO 63341
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  $1,495,000

  • 4 Beds
  • 4.5 Baths
  • 6,000 Sq Ft

  725 Crown Pointe Farms, Defiance, MO 63341

  Discover refined living in this stunning 1.5-story home, nestled on 3 private, wooded acres in an exclusive Defiance neighborhood. With over 6,000 sq ft of luxury, this thoughtfully designed home impresses at every turn. The two-story great room features hardwood floors, soaring ceilings, and a cozy double-sided fireplace shared with the hearth room—perfect for taking in serene views of the

  Chad Wilson Keller Williams Realty West

  725 Crown Pointe Farms, Defiance, MO 63341
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  $715,000 Open Sun 1PM - 3PM

  • 4 Beds
  • 3.5 Baths
  • 3,132 Sq Ft

  1329 Lakeway Dr, Defiance, MO 63341

  Welcome to your new home with 3 car oversized side entry garage! This beautiful 4 bed, 3 1/2 bath 2 story is waiting for its new family, Once you walk into the entry way with beautiful hardwood floors you will go to the 2 story great room with a wood burning fireplace, Large windows over looking your beautiful 3 acre lot backing to woods. The hardwood floors continue from the breakfast room

  Cindy Williams Fox & Riley Real Estate

  1329 Lakeway Dr, Defiance, MO 63341
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  /55

  $289,900

  • 4 Beds
  • 2 Baths
  • 1,848 Sq Ft

  16 Garrett Ln, Defiance, MO 63341

  Exceptional 4 bedroom, 2 bath double wide manufactured home on a little over an acre of beautiful property that is only a couple minutes from both Weldon Spring Katy Trail and Defiance Katy Trail access. Nice large covered front porch and new roof June 2025! Enter into the spacious living room with vaulted ceilings that open to the gorgeous kitchen. The kitchen offers a large center island with

  Andy Boyd Keller Williams Realty St. Louis

  16 Garrett Ln, Defiance, MO 63341
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  $502,000

  • Land
  • 5 Acres
  • $100,000 per Acre

  60 Lakefront Ct, Defiance, MO 63341

  Welcome to Lot #60 in Callaway Lake Estates, an exclusive luxury subdivision nestled in the serene countryside of unincorporated Saint Charles County, Missouri. This prestigious community offers 108 breathtaking lots, ranging from 5 to 15 acres, providing the perfect canvas for your custom dream home. With a minimum build requirement of 2,400 sq. ft. and architectural approval, each estate

  Toni Dillon Trophy Properties & Auction

  60 Lakefront Ct, Defiance, MO 63341
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  $325,000

  • Land
  • 5.00 Acres
  • $65,000 per Acre

  525 Callaway Estates Dr, Defiance, MO 63341

  Welcome to Callaway Lake Estates...Lot #5, an exclusive luxury subdivision nestled in the serene countryside of unincorporated Saint Charles County, Missouri. This prestigious community offers 108 breathtaking lots, ranging from 5 to 15 acres, providing the perfect canvas for your custom dream home. With a minimum build requirement of 2,400 sq. ft. and architectural approval, each estate combines

  Toni Dillon Trophy Properties & Auction

  525 Callaway Estates Dr, Defiance, MO 63341
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  $319,900

  • Land
  • 5.00 Acres
  • $63,980 per Acre

  5010 Lily Ridge, Defiance, MO 63341

  Sunset Estates in St. Charles County MO. Four Luxurious home sites, on 5 acre lots. Located in the heart of Defiance and wine country. Bring your own builder/plans and build your dream home on one of these premium secluded, all wooded lots. Homesites are located on a private street with cul-de-sac. Homeowners will enjoy the peace and quiet, along with privacy. County water and high-speed

  Bill McNair II First American Real Estate Co.

  5010 Lily Ridge, Defiance, MO 63341
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  /4

  $319,900

  • Land
  • 5.00 Acres
  • $63,980 per Acre

  5000 Lily Ridge, Defiance, MO 63341

  Sunset Estates in St. Charles County MO. Four Luxurious home sites, on 5 acre lots. Located in the heart of Defiance and wine country. Bring your own builder/plans and build your dream home on one of these premium secluded, all wooded lots. Homesites are located on a private street with cul-de-sac. Homeowners will enjoy the peace and quiet, along with privacy. County water and high-speed

  Bill McNair II First American Real Estate Co.

  5000 Lily Ridge, Defiance, MO 63341
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  /4

  $279,900

  • Land
  • 5.00 Acres
  • $55,980 per Acre

  5011 Lily Ridge, Defiance, MO 63341

  Sunset Estates in St. Charles County MO. Four Luxurious home sites, on 5 acre lots. Located in the heart of Defiance and wine country. Bring your own builder/plans and build your dream home on one of these premium secluded, all wooded lots. Homesites are located on a private street with cul-de-sac. Homeowners will enjoy the peace and quiet, along with privacy. County water and high-speed

  Bill McNair II First American Real Estate Co.

  5011 Lily Ridge, Defiance, MO 63341
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  /5

  $279,900

  • Land
  • 5.00 Acres
  • $55,980 per Acre

  5001 Lily Ridge Ct, Defiance, MO 63341

  Four Luxurious home sites, on 5 acre lots. Sunset Estates in St. Charles County MO. Located in the heart of Defiance and wine country. Bring your own builder/plans and build your dream home on one of these premium secluded, all wooded lots. Homesites are located on a private street with cul-de-sac. Homeowners will enjoy the peace and quiet, along with privacy. County water and high-speed

  Bill McNair II First American Real Estate Co.

  5001 Lily Ridge Ct, Defiance, MO 63341
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  /4

  $420,800

  • Land
  • 5 Acres
  • $80,000 per Acre

  449 Stones Throw Ct, Defiance, MO 63341

  Welcome to Callaway Lake Estates, an exclusive luxury subdivision nestled in the serene countryside of unincorporated Saint Charles County, Missouri. This prestigious community offers 108 breathtaking lots, ranging from 5 to 15 acres, providing the perfect canvas for your custom dream home. With a minimum build requirement of 2,400 sq. ft. and architectural approval, each estate combines elegance

  Toni Dillon Trophy Properties & Auction

  449 Stones Throw Ct, Defiance, MO 63341
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  $899,900

  0 Callaway Ridge Dr Unit MIS25044862, Defiance, MO 63341

  Fabulous acreage for private estate or premier development land (cannot be subdivided less than 5 acre lots) on scenic Callaway Ridge Drive in Defiance! The land, approximately 30 acres, providing a spectacular view from the top, offers a combination of open land, with numerous home sites, and wooded land with timber. Along the road frontage is the peak of ridge top with level to sloping land.

  Catherine Shaw-Connely Tom Shaw, REALTORS

  0 Callaway Ridge Dr Unit MIS25044862, Defiance, MO 63341
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  $650,000

  • 3 Beds
  • 2 Baths
  • 2,336 Sq Ft

  50 Wilderness Ln, Defiance, MO 63341

  Rare opportunity to have a beautiful 4 year "new" ranch home located in a much sought after, established community in the Defiance area. Just minutes to I-64 and Hwy 94 allowing easy commutes and peaceful country living. Upon entering you will be impressed by the 11 ft ceilings and all of the natural light that fills this entertaining area. The kitchen offers tons of white cabinets, stainless

  Maureen Blondin Blondin Group, Inc

  50 Wilderness Ln, Defiance, MO 63341
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  $1,900,000

  • 5 Beds
  • 5.5 Baths
  • 9,188 Sq Ft

  701 Crown Pointe Farms, Defiance, MO 63341

  Tucked away at the end of a quiet cul-de-sac in one of Defiance’s most sought-after communities, 701 Crown Pointe Farms offers unmatched privacy and space—all set on 10.39 wooded acres. This breathtaking estate boasts over 9,000 sq ft of finished living space, including a separate in-law apartment and an entertainer’s dream of a lower level. The resort-style backyard features a heated & cooled

  Matthew Becker Magnolia Real Estate

  701 Crown Pointe Farms, Defiance, MO 63341
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  /3

  $161,920

  • Land
  • 5 Acres
  • $32,000 per Acre

  120 Steeple Point Dr Lot #13 Dr, Defiance, MO 63341

  Another Great Lot in the Steeple Point Subdivision. Schedule your appointment to view today.

  Dan Lauderdale Lauderdale Realty

  120 Steeple Point Dr Lot #13 Dr, Defiance, MO 63341
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  /3

  $248,920

  • Land
  • 9 Acres
  • $28,000 per Acre

  110 Steeple Point Dr Lot # 14 Dr, Defiance, MO 63341

  WOW, nearly 9 acres for under $250,000. Schedule an appointment and view this lot today.

  Dan Lauderdale Lauderdale Realty

  110 Steeple Point Dr Lot # 14 Dr, Defiance, MO 63341
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  $161,600

  • Land
  • 5 Acres
  • $32,000 per Acre

  130 Steeple Point Dr Lot #12 Dr, Defiance, MO 63341

  Great Building Lot. Schedule an appointment and view this property today.

  Dan Lauderdale Lauderdale Realty

  130 Steeple Point Dr Lot #12 Dr, Defiance, MO 63341
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  /5

  $164,160

  • Land
  • 5 Acres
  • $32,000 per Acre

  150 Steeple Point Dr Lot #10 Dr, Defiance, MO 63341

  Gorgeous Lot in Steeple Point. Great views and quite living.

  Dan Lauderdale Lauderdale Realty

  150 Steeple Point Dr Lot #10 Dr, Defiance, MO 63341
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  /2

  $300,160

  • Land
  • 11 Acres
  • $28,000 per Acre

  190 Steeple Point Dr Lot #6 Dr, Defiance, MO 63341

  Great home site in a rural setting.

  Dan Lauderdale Lauderdale Realty

  190 Steeple Point Dr Lot #6 Dr, Defiance, MO 63341
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  $160,960

  • Land
  • 5 Acres
  • $32,000 per Acre

  180 Steeple Point Dr Lot #7 Dr, Defiance, MO 63341

  Awesome lot available in a rural subdivision

  Dan Lauderdale Lauderdale Realty

  180 Steeple Point Dr Lot #7 Dr, Defiance, MO 63341
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  /6

  $629,900

  • Land
  • 10 Acres
  • $62,990 per Acre

  151 Matson Hill Rd, Defiance, MO 63341

  Welcome to an extraordinary land opportunity in Missouri Wine Country. Perched high on the bluffs above the Missouri River, this breathtaking 10-acre estate offers incredible views that stretch across the rolling countryside—an unmatched backdrop for your dream home, luxury retreat, or next big vision. Located just three miles south of Defiance, this property sits at the epicenter of elegance and

  Ryan Zimmer Coldwell Banker Realty - Gundaker

  151 Matson Hill Rd, Defiance, MO 63341
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  $449,999

  • 4 Beds
  • 3 Baths
  • 2,847 Sq Ft

  5 Cedar Fork Ct, Defiance, MO 63341

  Looking for acreage in St. Charles County? Your search ends here! Don’t miss this 4BR/3BA hidden gem perfectly situated on a 3-acre lot in Defiance, providing a tranquil retreat. The wrap-around deck offers endless outdoor relaxation. Inside, large windows connect the indoors to the surrounding beauty. The vaulted living room features a cozy wood burning FP, and the kitchen includes a peninsula,

  Chad Matlick Coldwell Banker Realty - Gundaker

  5 Cedar Fork Ct, Defiance, MO 63341
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  $675,000

  • 5 Beds
  • 4.5 Baths
  • 4,140 Sq Ft

  3856 Rooster Ridge Ln, Defiance, MO 63341

  Prepare to be WOWED! Impressive 1.5 story on a 3.2 AC, wooded lot for nature-loving buyers who enjoy the outdoors. This peaceful setting creates a picturesque back-drop for an amazing home. The ext is impressive w/brick, 4 bay windows, 3 car gar, arch shingles (1 yr old), leaded glass door and a large front porch. Features inc 4,140 s/f of living space, 5 BD, 4.5 BA, 2 story Grt Rm w/window wall,

  Kelly Boehmer Berkshire Hathaway HomeServices Select Properties

  3856 Rooster Ridge Ln, Defiance, MO 63341
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  $194,900

  • Land
  • 3.01 Acres
  • $64,751 per Acre

  121 Red Barn Ln, Defiance, MO 63341

  Your plans, your builder. Level, open lot with woods along the back line. The last unbuilt lot remaining. One of only (9) lots in Femme Osage Valley subdivision. Public water. Blacktop Streets. 10 minutes from Hwy 40/61. Additional Rooms: In Platted Subdv.

  John Shaw Tom Shaw, REALTORS

  121 Red Barn Ln, Defiance, MO 63341
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  $419,900

  • 4 Beds
  • 1 Bath
  • 1,321 Sq Ft

  130 Defiance Rd, Defiance, MO 63341

  Charming rustic farmhouse in excellent condition, nestled in the heart of downtown Defiance. This home offers stunning views of the Missouri River bottoms from the front porch, providing a serene and picturesque setting. Ideal for a short-term rental investment or as a cozy permanent residence. With its well-preserved character and prime location, this property offers both comfort and potential

  Tony Schulte MO Realty

  130 Defiance Rd, Defiance, MO 63341
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  /17

  $219,900

  • Land
  • 14 Acres
  • $15,378 per Acre

  0 Steeple Rock Unit MAR24075687, Defiance, MO 63341

  Beautiful building lot St. Charles County area of Defiance! All wooded with grand rock outcroppings and mature timber! Come build your dream home on the ridge overlooking the wooded valley and draws below. The drive coming down Callaway Fork Road is breathtaking as well. Where else in St. Charles County can you find 14+ Acres to call your own at this price and located in the Francis Howell School

  Eric Merchant Trophy Properties & Auction

  0 Steeple Rock Unit MAR24075687, Defiance, MO 63341
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  /5

  $684,320

  26 Callaway Ridge Dr, Defiance, MO 63341

  Discover your private oasis on this rare 28.1-acre parcel in the sought-after Callaway Valley Subdivision! Perfect for your dream home or personal estate, this expansive property offers serene seclusion amidst lush nature, with the flexibility to create up to four ideal building sites. Surrounded by custom homes on private roads and located within the highly regarded Francis Howell School

  Suzanne Matyiko Berkshire Hathaway HomeServices Alliance Real Estate

  26 Callaway Ridge Dr, Defiance, MO 63341
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  /2

  $1,460,000

  • Land
  • 40 Acres
  • $36,500 per Acre

  4834 Highway D, Defiance, MO 63341

  Stunning 40+- Acre Rural Retreat – Endless Possibilities Await!Discover the beauty and serenity of this 40+-- acre gem in the heart of nature! Nestled in the highly sought-after Francis Howell School District, this picturesque property offers rolling hills, open fields, and scattered wooded areas, creating the perfect blend of open space and privacy. A scenic creek meanders through the

  Tom Shaw Tom Shaw, REALTORS

  4834 Highway D, Defiance, MO 63341
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  /2

  $115,000

  • Land
  • 7 Acres
  • $16,429 per Acre

  0 Steeple Rock Unit MAR25019055, Defiance, MO 63341

  Beautiful building lot St. Charles County area of Defiance! All wooded with grand rock outcroppings and mature timber! Come build your dream home on the ridge overlooking the wooded valley and draws below. The drive coming down Callaway Fork Road is breathtaking as well. Where else in St. Charles County can you find 7+ Acres to call your own at this price and located in the Francis Howell School

  Eric Merchant Trophy Properties & Auction

  0 Steeple Rock Unit MAR25019055, Defiance, MO 63341
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  /2

  $135,000

  • Land
  • 7 Acres
  • $19,286 per Acre

  0 Steeple Rock Unit MAR25019015, Defiance, MO 63341

  Beautiful building lot St. Charles County area of Defiance! All wooded with grand rock outcroppings and mature timber! Come build your dream home on the ridge overlooking the wooded valley and draws below. The drive coming down Callaway Fork Road is breathtaking as well. Where else in St. Charles County can you find 7+ Acres to call your own at this price and located in the Francis Howell School

  Eric Merchant Trophy Properties & Auction

  0 Steeple Rock Unit MAR25019015, Defiance, MO 63341
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  /13

  $165,440

  • Land
  • 5 Acres
  • $32,000 per Acre

  160 Steeple Point Dr Lot #9 Dr, Defiance, MO 63341

  Dan Lauderdale Lauderdale Realty

  160 Steeple Point Dr Lot #9 Dr, Defiance, MO 63341

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