20

Defiance, MO Houses for Sale

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  • /43

    $899,999

    $50K PRICE DROP
    • 4 Beds
    • 4.5 Baths
    • 4,579 Sq Ft

    50 Sunfish Dr, Defiance, MO 63341

    Experience the best of Callaway Valley living—where privacy, luxury, and lifestyle align.Situated on a stunning 6-acre estate with coveted lake rights, this exceptional property offers a rare blend of space, serenity, and high-end living.The heart of the home is a chef’s dream kitchen, beautifully updated in 2022 with a 48” Wolf gas range with pot filler, Sub-Zero refrigerator, expansive

    Agent Photo

    Amanda Alejandro

    Realty Shop

    50 Sunfish Dr, Defiance, MO 63341
  • /87

    $950,000

    • 4 Beds
    • 5 Baths
    • 4,298 Sq Ft

    4075 Highway D, Defiance, MO 63341

    Luxury country living meets everyday convenience on this exceptional 10 unrestricted acre estate! Perfectly situated just minutes from Highway 40/61, Highway N, Winghaven shopping, New Melle, Augusta, and Defiance, you’ll enjoy the peace and privacy of country living while remaining close to award-winning wineries, restaurants, shopping, and an easy commute.Beautifully updated and

    Agent Photo

    Samantha Richardson

    Main St. Real Estate

    4075 Highway D, Defiance, MO 63341
  • /99

    $1,690,000

    $100K PRICE DROP
    • 4 Beds
    • 3.5 Baths
    • 5,609 Sq Ft

    4325 Hueffmeier Rd, Defiance, MO 63341

    Welcome home to this beautifully appointed brick ranch that truly has it all—inside and out. Situated on approximately 10+/- acres, this property offers the perfect blend of privacy, space, and resort-style living. Step into your own private backyard retreat featuring a stunning in-ground saltwater pool (9.5 ft deep), complete with heating and cooling for extended seasonal enjoyment. The

    Scott Dyer MO Realty

    4325 Hueffmeier Rd, Defiance, MO 63341
  • /6

    $1

    • 3 Beds
    • 4 Baths
    • 2,090 Sq Ft

    1 Country Life, Defiance, MO 63341

    Improvements include a 2090 sq. ft. ranch home built in 1980. The home features 3 bedrooms, 2 full baths & 2 half baths, custom kitchen/breakfast room w/updated stainless steel appliances & granite marble top center island & counter tops, great room w/woodburning stone fireplace, wood floors, formal dining room, formal entry, main floor laundry, huge master bedroom w/large master bath w/tub &

    Dusty Thornhill Thornhill Real Estate & Auction Co

    1 Country Life, Defiance, MO 63341
  • /52

    $625,000

    Open Sun 1PM - 3PM
    • 4 Beds
    • 2.5 Baths
    • 2,096 Sq Ft

    44 Wilderness Ln, Defiance, MO 63341

    Tucked away at the end of a cul-de-sac and lined by trees on a gorgeous 3 acre lot this lovely, private hideaway is calling you home to a welcoming 2 story gem, Woodworking Shop or She shed, Barn and pasture. Enter to ceramic tile entry, coat closet and powder room. Grand staircase in entry with wood rails and wrought iron balusters. Large L shaped great room with solid oak floors and wood stove.

    Mike Simms Worth Clark Realty

    44 Wilderness Ln, Defiance, MO 63341
  • /56

    $850,000

    Pending
    • 5 Beds
    • 5 Baths
    • 4,749 Sq Ft

    769 Old Colony Rd, Defiance, MO 63341

    Experience refined country living in the heart of Missouri wine country at this stunning custom-built brick atrium ranch in Defiance. Nestled on approximately 5 picturesque acres, this exceptional estate offers nearly 5,000 square feet of beautifully finished living space designed for both luxury and comfort. Step inside and be captivated by the dramatic atrium wall of windows that floods the

    Lori Dillick Coldwell Banker Realty - Gundaker

    769 Old Colony Rd, Defiance, MO 63341
  • /79

    $1,400,000

    Pending
    • 5 Beds
    • 7 Baths
    • 6,521 Sq Ft

    220 Northlind Dr, Defiance, MO 63341

    Stunning brick and stone ranch-style home sitting on 3 private acres surrounded by mature trees and scenic views! This custom-built home boasts 5 bedrooms, 4 full bathrooms, 3 half bathrooms, and over 6,500 square feet of living space including the finished walkout lower level. The property also features an attached 3 car garage and a detached 52 x 40 foot detached garage with a bonus room. The

    Mark Gellman EXP Realty, LLC

    220 Northlind Dr, Defiance, MO 63341
  • /73

    $489,000

    Pending
    • 3 Beds
    • 2 Baths
    • 2,156 Sq Ft

    7 Wilderness Ln, Defiance, MO 63341

    Hard to Find Log Cabin on 3 very usable Acres in the Heart of Defiance! Get ready to unleash your inner explorer at 7 Wilderness Lane. Built in 1978, this charming single-family lob cabin-type home is more than just a residence—it’s your gateway to adventure and peaceful country living. Inside, you’ll find three cozy bedrooms and two full bathrooms, thoughtfully designed for everyday comfort and

    Sandi Alexander RE/MAX EDGE

    7 Wilderness Ln, Defiance, MO 63341
  • /44

    $1,430,000

    $69K PRICE DROP Pending
    • 4 Beds
    • 3.5 Baths
    • 4,461 Sq Ft

    115 Markham Trail Ln, Defiance, MO 63341

    Looking for the perfect multi-generational home or private in-law suite with its own entrance? This custom-built Lombardo Ranch on 5.44 acres checks every box. Thoughtfully designed with high-end upgrades throughout, this home blends style, comfort, and function in every detail.On the main level, you’ll find a chef’s kitchen featuring white custom cabinetry, quartz countertops, a striking

    Madison Lantz Berkshire Hathaway HomeServices Select Properties

    115 Markham Trail Ln, Defiance, MO 63341
  • /18

    $650,000

    • 3 Beds
    • 2 Baths
    • 2,013 Sq Ft

    215 Rugged Acres Ln, Defiance, MO 63341

    Custom built, beautifully crafted home with over 2,000 sq feet of living space with luxury finishes. Located on 5 unrestricted acres, mostly wooded, outside New Melle in the heart of wine country. Private and peacefully located with access to major roads, living in country with easy access to all modern conveniences. Stepping Inside you are greeted with soaring 10' ceilings, open floor plan from

    Dolly Sjoholm Call Dolly, LLC

    215 Rugged Acres Ln, Defiance, MO 63341
  • /37

    $535,000

    $14K PRICE DROP
    • 3 Beds
    • 2 Baths
    • 1,600 Sq Ft

    3877 Highway D, Defiance, MO 63341

    Spacious ranch on 6 gorgeous acres conveniently located just minutes from wineries, schools, shopping and highways! This charming 3 bedroom, 2 bath home comes complete with main floor laundry, full, unfinished basement, and a primary bedroom with walk-in closet and ensuite bath. Besides the 2-car attached garage, there is a 28’x60’ insulated metal outbuilding with concrete floor, electric and 220

    Sherry Raleigh-Adams Wolfe Realty

    3877 Highway D, Defiance, MO 63341
  • /50

    $749,900

    $45K PRICE DROP
    • 4 Beds
    • 3.5 Baths
    • 4,564 Sq Ft

    2 Woodridge Dr, Defiance, MO 63341

    This spacious 4 bedroom 4 bath ranch home is beautifully situated on a 3 acre wooded lot creating a private, peaceful oasis which features a saltwater pool with waterfall, perfect for relaxing and entertaining. The recently refinished wide-plank hardwood floors are simply outstanding. A large living/family room with fireplace leads to an outdoor brick terrace. The family dining area with

    John Zarky Janet McAfee Inc.

    2 Woodridge Dr, Defiance, MO 63341
  • /10

    $499,900

    Under Contract
    • 3 Beds
    • 2.5 Baths
    • 1,978 Sq Ft

    2540 S Highway 94, Defiance, MO 63341

    Country living on 5.21+/- level STUNNING acres in unincorporated Defiance! A tree lined driveway leads to a CHARMING, RANCH home with 3 bedrooms, 2.5 baths & 1,978+/- SqFt of living space that offers an AWESOME, 30’ x 24’, 2-car, detached garage & shed. Partially covered front porch greets you as you step inside the entry foyer. Step down, living room boasts a floor-to-ceiling brick wood burning

    Catherine Shaw-Connely Tom Shaw, REALTORS

    2540 S Highway 94, Defiance, MO 63341
  • /78

    $620,000

    • 4 Beds
    • 3.5 Baths
    • 3,057 Sq Ft

    8 Whippoorwill Ct, Defiance, MO 63341

    Escape to your own private retreat with this stunning log home nestled on 3 picturesque acres, where peaceful country living meets modern comfort. Surrounded by mature trees and breathtaking natural beauty, you'll enjoy the serenity of nature while remaining just 15 minutes from Highway 40, offering the perfect balance of privacy and convenience. Enjoy the view from either the fully covered front

    Jennifer Bommarito Fox & Riley Real Estate

    8 Whippoorwill Ct, Defiance, MO 63341
  • /67

    $2,750,000

    $25K PRICE DROP
    • 3 Beds
    • 4.5 Baths
    • 4,037 Sq Ft

    353 Callaway Ridge Dr, Defiance, MO 63341

    Experience the ultimate in privacy and natural beauty with this stunning custom waterfront property nestled on 37+ mostly wooded acres fronting the serene waters of Callaway Valley Lake. Crafted with exceptional attention to detail, this one-of-a-kind property showcases rich woodwork and impeccable craftsmanship throughout. Highlighted by a grand wood-paneled ceiling with softly arched beams, and

    Kelly Beanblossom-Schlake Blondin Group, Inc

    353 Callaway Ridge Dr, Defiance, MO 63341
  • /43

    $679,900

    $20K PRICE DROP
    • 3 Beds
    • 2.5 Baths
    • 1,944 Sq Ft

    1451 Highway F, Defiance, MO 63341

    Rarely does an opportunity like this come available in Defiance! Located in the beautiful Femme Osage valley, nestled on 9+ picturesque acres, this 3 bed, 2.5 home offers the perfect blend of privacy, space, and comfort. The setting is rural but convenient to highway 64/40, Chesterfield, Wentzville, and Francis Howell schools. Step inside to find hardwood floors throughout the main level, leading

    Matthew Lauman Magnolia Real Estate

    1451 Highway F, Defiance, MO 63341
  • /40

    $625,000

    $25K PRICE DROP
    • 5 Beds
    • 3 Baths
    • 3,391 Sq Ft

    1510 Highway Dd, Defiance, MO 63341

    Welcome to 1510 Highway DD in unincorporated St. Charles County and in the Francis Howell School District. Nestled on 3 beautiful acres in St. Charles County, this rare 5 bedroom ranch offers the perfect blend of peaceful living while keeping you just minutes from shopping, restaurants, and major highways. Step inside to find an expansive open layout where the kitchen is a true centerpiece,

    Timothy Koppel Berkshire Hathaway HomeServices Select Properties

    1510 Highway Dd, Defiance, MO 63341
  • /69

    $2,375,000

    • 3 Beds
    • 4.5 Baths
    • 4,037 Sq Ft

    353 Callaway Ridge (25 5) Dr, Defiance, MO 63341

    Experience the ultimate in privacy and natural beauty with this stunning custom waterfront property nestled on 25.5+/- mostly wooded acres with frontage on the serene waters of Callaway Valley Lake. Crafted with exceptional attention to detail, this one-of-a-kind property showcases rich woodwork and impeccable craftsmanship throughout. Highlighted by a grand wood-paneled ceiling with softly

    Kelly Beanblossom-Schlake Blondin Group, Inc

    353 Callaway Ridge (25 5) Dr, Defiance, MO 63341
  • /32

    $379,950

    • 3 Beds
    • 1 Bath
    • 1,296 Sq Ft

    3901 Highway D, Defiance, MO 63341

    Ranch style, full brick home situated on 4.6 acres with an attached one car garage. The home has 3 bedrooms, 1 bath, 1296 square feet, some hardwood floors, and a full basement situated on a fairly level lot. Some photos are virtually staged.

    Michelle Syberg Mid America Property Partners

    3901 Highway D, Defiance, MO 63341
  • /53

    $649,900

    • 4 Beds
    • 3 Baths
    • 2,479 Sq Ft

    800 Matson Hill Rd, Defiance, MO 63341

    Nestled on 8+ scenic acres off coveted Matson Hill Road in Unincorporated St. Charles County, this meticulously maintained retreat offers the perfect blend of refined comfort and peaceful country living. Surrounded by mature trees, wildlife, and nature, this stunning property delivers privacy without sacrificing convenience. Welcoming foyer opens to formal living and dining rooms before leading

    Suzanne Matyiko ReeceNichols Real Estate

    800 Matson Hill Rd, Defiance, MO 63341

Single Family Home Price Trends

Median Home Price
$677,450
Median 3-Bedroom Home Price
$475,000
Median 4-Bedroom Home Price
$675,000
Median 5-Bedroom Home Price
$1,100,000
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