27

Newest Homes for Sale in Defiance, MO

Section Image
  • 640 Callaway Ridge Dr, Defiance, MO 63341
    640 Callaway Ridge Dr, Defiance, MO 63341
    640 Callaway Ridge Dr, Defiance, MO 63341
    /45

    $575,000

    • 4 Beds
    • 3.5 Baths
    • 1,922 Sq Ft

    640 Callaway Ridge Dr, Defiance, MO 63341

    Discover the perfect blend of privacy, recreation and thoughtful updates in this 2-story home set on 3.24 picturesque acres in desirable Callaway Valley.Offering 4 bedrooms and 3.5 baths with 1,922 sf of finished living space above grade, this home delivers both functionality and flexibility. Numerous updates have been completed throughout, including refreshed bathrooms and improvements

    Julie Burt Blondin Group, Inc

    640 Callaway Ridge Dr, Defiance, MO 63341
  • 4075 Highway D, Defiance, MO 63341
    4075 Highway D, Defiance, MO 63341
    4075 Highway D, Defiance, MO 63341
    /30

    $999,999

    • 4 Beds
    • 5 Baths
    • 2,436 Sq Ft

    4075 Highway D, Defiance, MO 63341

    NOT IN A SUBDIVISION, NO INDENTURES OR RESTRICTIONS!!!! NEW ROOF.This is a must see!!! This beautifully updated, well maintained home with 3 beds, (3) full (2) 1/2 baths is on 10 flat acres. Primary bedroom has a bay window, separate shower/jacuzzi tub. Family room has a wood burning fireplace. Relax on the covered porch that overlooks a water feature and the lake. Kitchen has granite

    John Shaw Tom Shaw, REALTORS

    4075 Highway D, Defiance, MO 63341
  • 2 Woodridge Dr, Defiance, MO 63341
    2 Woodridge Dr, Defiance, MO 63341
    2 Woodridge Dr, Defiance, MO 63341
    /91

    $799,000

    • 5 Beds
    • 3.5 Baths
    • 4,564 Sq Ft

    2 Woodridge Dr, Defiance, MO 63341

    Spacious ranch home on 3 acres in one of the most beautiful settings in St. Charles County. Welcome home to picturesque rustic hardwood floors, a spacious country kitchen, large windows, vaulted ceilings, and TWO cozy fireplaces. The front, back, and side yards boast lovely mature trees placed perfectly to enhance the view and privacy. The pool (complete with a waterfall, salt water, and heater)

    Kathleen Helbig EXP Realty, LLC

    2 Woodridge Dr, Defiance, MO 63341
  • 180 Steeple Point Dr Lot #7 Dr, Defiance, MO 63341
    180 Steeple Point Dr Lot #7 Dr, Defiance, MO 63341
    180 Steeple Point Dr Lot #7 Dr, Defiance, MO 63341
    /4

    $151,000

    • Land
    • 5.03 Acres
    • $30,020 per Acre

    180 Steeple Point Dr Lot #7 Dr, Defiance, MO 63341

    Awesome lot available in a rural subdivision

    Dan Lauderdale Lauderdale Realty

    180 Steeple Point Dr Lot #7 Dr, Defiance, MO 63341
  • 130 Steeple Point Dr Lot #12 Dr, Defiance, MO 63341
    130 Steeple Point Dr Lot #12 Dr, Defiance, MO 63341
    130 Steeple Point Dr Lot #12 Dr, Defiance, MO 63341
    /9

    $151,000

    • Land
    • 5.05 Acres
    • $29,901 per Acre

    130 Steeple Point Dr Lot #12 Dr, Defiance, MO 63341

    Great Building Lot. Schedule an appointment and view this property today.

    Dan Lauderdale Lauderdale Realty

    130 Steeple Point Dr Lot #12 Dr, Defiance, MO 63341
  • 110 Steeple Point Dr Lot # 14 Dr, Defiance, MO 63341
    110 Steeple Point Dr Lot # 14 Dr, Defiance, MO 63341
    /2

    $238,900

    • Land
    • 8.89 Acres
    • $26,873 per Acre

    110 Steeple Point Dr Lot # 14 Dr, Defiance, MO 63341

    WOW, nearly 9 acres for under $250,000. Schedule an appointment and view this lot today.

    Dan Lauderdale Lauderdale Realty

    110 Steeple Point Dr Lot # 14 Dr, Defiance, MO 63341
  • 150 Steeple Point Dr Lot #10 Dr, Defiance, MO 63341
    150 Steeple Point Dr Lot #10 Dr, Defiance, MO 63341
    150 Steeple Point Dr Lot #10 Dr, Defiance, MO 63341
    /4

    $154,000

    • Land
    • 5.13 Acres
    • $30,019 per Acre

    150 Steeple Point Dr Lot #10 Dr, Defiance, MO 63341

    Gorgeous Lot in Steeple Point. Great views and quite living.

    Dan Lauderdale Lauderdale Realty

    150 Steeple Point Dr Lot #10 Dr, Defiance, MO 63341
  • 190 Steeple Point Dr Lot #6 Dr, Defiance, MO 63341
    190 Steeple Point Dr Lot #6 Dr, Defiance, MO 63341
    /2

    $290,000

    • Land
    • 10.72 Acres
    • $27,052 per Acre

    190 Steeple Point Dr Lot #6 Dr, Defiance, MO 63341

    Great home site in a rural setting.

    Dan Lauderdale Lauderdale Realty

    190 Steeple Point Dr Lot #6 Dr, Defiance, MO 63341
  • 120 Steeple Point Dr Lot #13 Dr, Defiance, MO 63341
    120 Steeple Point Dr Lot #13 Dr, Defiance, MO 63341
    /2

    $152,000

    • Land
    • 5.06 Acres
    • $30,040 per Acre

    120 Steeple Point Dr Lot #13 Dr, Defiance, MO 63341

    Another Great Lot in the Steeple Point Subdivision. Schedule your appointment to view today.

    Dan Lauderdale Lauderdale Realty

    120 Steeple Point Dr Lot #13 Dr, Defiance, MO 63341
  • 160 Steeple Point Dr Lot #9 Dr, Defiance, MO 63341
    160 Steeple Point Dr Lot #9 Dr, Defiance, MO 63341
    160 Steeple Point Dr Lot #9 Dr, Defiance, MO 63341
    /12

    $155,000

    • Land
    • 5.17 Acres
    • $29,981 per Acre

    160 Steeple Point Dr Lot #9 Dr, Defiance, MO 63341

    Dan Lauderdale Lauderdale Realty

    160 Steeple Point Dr Lot #9 Dr, Defiance, MO 63341
  • 1330 Lake Hollow Dr, Defiance, MO 63341
    1330 Lake Hollow Dr, Defiance, MO 63341
    1330 Lake Hollow Dr, Defiance, MO 63341
    /47

    $689,900

    • 4 Beds
    • 2.5 Baths
    • 2,556 Sq Ft

    1330 Lake Hollow Dr, Defiance, MO 63341

    Enjoy the serenity of your own private retreat, surrounded by trees and nature while still being just minutes from shopping, dining, and entertainment. Inside, the stunning kitchen is a true showpiece—featuring quartz countertops, cherry cabinetry, stainless steel appliances, a massive island, and a spacious walk-in pantry. The main level shines with new 5” wide wood-plank luxury vinyl flooring,

    Suzanne Matyiko ReeceNichols Real Estate

    1330 Lake Hollow Dr, Defiance, MO 63341
  • 2934 S Highway 94, Defiance, MO 63341
    2934 S Highway 94, Defiance, MO 63341
    2934 S Highway 94, Defiance, MO 63341
    /51

    $385,000

    • 3 Beds
    • 2 Baths
    • 1,225 Sq Ft

    2934 S Highway 94, Defiance, MO 63341

    Refurbished 100-year-old historic home in the heart of Defiance wine country, offering rare character and flexible potential. This property is ideal for buyers seeking lifestyle, income opportunity, or a creative use rather than a traditional suburban layout. Completely updated while preserving original charm. Currently zoned residential and well-suited for short-term rental use (buyer to

    Chris Neskar Compass Realty Group

    2934 S Highway 94, Defiance, MO 63341
  • 3780 Forest Meadow Dr, Defiance, MO 63341
    3780 Forest Meadow Dr, Defiance, MO 63341
    3780 Forest Meadow Dr, Defiance, MO 63341
    /92

    $830,000

    • 5 Beds
    • 3.5 Baths
    • 4,814 Sq Ft

    3780 Forest Meadow Dr, Defiance, MO 63341

    Experience refined country living in this stunning 1.5-story estate nestled on a peaceful 3.43-acre lot. This 5-bedroom, 3.5-bath home combines timeless design, modern updates, and luxurious comfort throughout. The gourmet kitchen impresses with white cabinetry, gleaming quartz countertops, a large center island, and an inviting eat-in peninsula. A spacious walk-in pantry and a convenient wet bar

    Emily Brophy MO Realty

    3780 Forest Meadow Dr, Defiance, MO 63341
  • 353 Callaway Ridge Dr, Defiance, MO 63341
    353 Callaway Ridge Dr, Defiance, MO 63341
    353 Callaway Ridge Dr, Defiance, MO 63341
    /70

    $2,775,000

    • 3 Beds
    • 4.5 Baths
    • 4,037 Sq Ft

    353 Callaway Ridge Dr, Defiance, MO 63341

    Experience the ultimate in privacy and natural beauty with this stunning custom waterfront property nestled on 37+ mostly wooded acres fronting the serene waters of Callaway Valley Lake. Crafted with exceptional attention to detail, this one-of-a-kind property showcases rich woodwork and impeccable craftsmanship throughout. Highlighted by a grand wood-paneled ceiling with softly arched beams, and

    Maureen Blondin Blondin Group, Inc

    353 Callaway Ridge Dr, Defiance, MO 63341
  • 440 Stones Throw Ct, Defiance, MO 63341
    440 Stones Throw Ct, Defiance, MO 63341
    440 Stones Throw Ct, Defiance, MO 63341
    /3

    $338,650

    • Land
    • 5.21 Acres
    • $65,000 per Acre

    440 Stones Throw Ct, Defiance, MO 63341

    Welcome to Callaway Lake Estates, an exclusive luxury subdivision nestled in the serene countryside of unincorporated Saint Charles County, Missouri. This prestigious community offers 108 breathtaking lots, ranging from 5 to 15 acres, providing the perfect canvas for your custom dream home. With a minimum build requirement of 2,400 sq. ft. and architectural approval, each estate combines elegance

    Stephen Kaiser Trophy Properties & Auction

    440 Stones Throw Ct, Defiance, MO 63341
  • 48 Watershed Ct, Defiance, MO 63341
    48 Watershed Ct, Defiance, MO 63341
    48 Watershed Ct, Defiance, MO 63341
    /3

    $412,800

    • Land
    • 6.88 Acres
    • $60,000 per Acre

    48 Watershed Ct, Defiance, MO 63341

    Welcome to Callaway Lake Estates, an exclusive luxury subdivision nestled in the serene countryside of unincorporated Saint Charles County, Missouri. This prestigious community offers 108 breathtaking lots, ranging from 5 to 15 acres, providing the perfect canvas for your custom dream home. With a minimum build requirement of 2,400 sq. ft. and architectural approval, each estate combines elegance

    Stephen Kaiser Trophy Properties & Auction

    48 Watershed Ct, Defiance, MO 63341
  • 521 Callaway Estates Dr, Defiance, MO 63341
    521 Callaway Estates Dr, Defiance, MO 63341
    521 Callaway Estates Dr, Defiance, MO 63341
    /3

    $325,000

    • Land
    • 5 Acres
    • $65,000 per Acre

    521 Callaway Estates Dr, Defiance, MO 63341

    Welcome to Callaway Lake Estates, an exclusive luxury subdivision nestled in the serene countryside of unincorporated Saint Charles County, Missouri. This prestigious community offers 108 breathtaking lots, ranging from 5 to 15 acres, providing the perfect canvas for your custom dream home. With a minimum build requirement of 2,400 sq. ft. and architectural approval, each estate combines elegance

    Stephen Kaiser Trophy Properties & Auction

    521 Callaway Estates Dr, Defiance, MO 63341
  • 2461 Highway F, Defiance, MO 63341
    2461 Highway F, Defiance, MO 63341
    2461 Highway F, Defiance, MO 63341
    /11

    $495,000

    • Land
    • 9.05 Acres
    • $54,696 per Acre

    2461 Highway F, Defiance, MO 63341

    9.05 acres in the Francis Howell School District offering a versatile opportunity for farming, recreation, or future building. The property is primarily level and features an established well operated by a solar pump with 5 frost free spigots throughout the southeastern side of the property, making it ideal for gardens, orchards or hobby farming. A private gravel driveway has been added on the

    Julie Burt Blondin Group, Inc

    2461 Highway F, Defiance, MO 63341
  • 404 Stones Throw Ct, Defiance, MO 63341
    404 Stones Throw Ct, Defiance, MO 63341
    404 Stones Throw Ct, Defiance, MO 63341
    /23

    $300,000

    • Land
    • 5.01 Acres
    • $59,907 per Acre

    404 Stones Throw Ct, Defiance, MO 63341

    Beautiful 5-acre building lot located in the highly sought-after gated community of Callaway Lake Estates! Bring your builder and design the home of your dreams while adhering to community building restrictions that help preserve the neighborhood’s character and value. Enjoy access to the 168-acre Callaway Lake, perfect for fishing, boating, and relaxing by the water. This prime lot is within the

    Tim Phillips MO Realty

    404 Stones Throw Ct, Defiance, MO 63341
  • 170 Blue Sky, Defiance, MO 63341
    170 Blue Sky, Defiance, MO 63341
    170 Blue Sky, Defiance, MO 63341
    /98

    $1,389,000 New Construction

    • 5 Beds
    • 5.5 Baths
    • 5,504 Sq Ft

    170 Blue Sky, Defiance, MO 63341

    Brand new custom-built home on 3+ wooded acres in Kohler Estates subdivision. Features 4 bedrooms and 5 1/2 baths, a oversized 4 car garage with stair access to basement, a Great Room with a stone gas fireplace, with custom bookshelves, Gourmet kitchen offers custom cabinetry with quartz countertops, tile backsplash, and a complete appliance package, and walk-in pantry with custom shelving.

    Chris Dawson Orenda Real Estate Services

    170 Blue Sky, Defiance, MO 63341
  • 60 Lakefront Ct, Defiance, MO 63341
    60 Lakefront Ct, Defiance, MO 63341
    60 Lakefront Ct, Defiance, MO 63341
    /4

    $502,000

    • Land
    • 5.02 Acres
    • $100,000 per Acre

    60 Lakefront Ct, Defiance, MO 63341

    Welcome to Lot #60 in Callaway Lake Estates, an exclusive luxury subdivision nestled in the serene countryside of unincorporated Saint Charles County, Missouri. This prestigious community offers 108 breathtaking lots, ranging from 5 to 15 acres, providing the perfect canvas for your custom dream home. With a minimum build requirement of 2,400 sq. ft. and architectural approval, each estate

    Toni Dillon Trophy Properties & Auction

    60 Lakefront Ct, Defiance, MO 63341
  • 525 Callaway Estates Dr, Defiance, MO 63341
    525 Callaway Estates Dr, Defiance, MO 63341
    525 Callaway Estates Dr, Defiance, MO 63341
    /4

    $325,000

    • Land
    • 5 Acres
    • $65,000 per Acre

    525 Callaway Estates Dr, Defiance, MO 63341

    Welcome to Callaway Lake Estates...Lot #5, an exclusive luxury subdivision nestled in the serene countryside of unincorporated Saint Charles County, Missouri. This prestigious community offers 108 breathtaking lots, ranging from 5 to 15 acres, providing the perfect canvas for your custom dream home. With a minimum build requirement of 2,400 sq. ft. and architectural approval, each estate combines

    Toni Dillon Trophy Properties & Auction

    525 Callaway Estates Dr, Defiance, MO 63341
  • 5011 Lily Ridge, Defiance, MO 63341
    5011 Lily Ridge, Defiance, MO 63341
    5011 Lily Ridge, Defiance, MO 63341
    /4

    $279,900

    • Land
    • 5 Acres
    • $55,980 per Acre

    5011 Lily Ridge, Defiance, MO 63341

    Sunset Estates in St. Charles County MO. Four Luxurious home sites, on 5 acre lots. Located in the heart of Defiance and wine country. Bring your own builder/plans and build your dream home on one of these premium secluded, all wooded lots. Homesites are located on a private street with cul-de-sac. Homeowners will enjoy the peace and quiet, along with privacy. County water and high-speed

    Bill McNair II First American Real Estate Co.

    5011 Lily Ridge, Defiance, MO 63341
  • 5000 Lily Ridge, Defiance, MO 63341
    5000 Lily Ridge, Defiance, MO 63341
    5000 Lily Ridge, Defiance, MO 63341
    /4

    $319,900

    • Land
    • 5 Acres
    • $63,980 per Acre

    5000 Lily Ridge, Defiance, MO 63341

    Sunset Estates in St. Charles County MO. Four Luxurious home sites, on 5 acre lots. Located in the heart of Defiance and wine country. Bring your own builder/plans and build your dream home on one of these premium secluded, all wooded lots. Homesites are located on a private street with cul-de-sac. Homeowners will enjoy the peace and quiet, along with privacy. County water and high-speed

    Bill McNair II First American Real Estate Co.

    5000 Lily Ridge, Defiance, MO 63341
  • 5001 Lily Ridge Ct, Defiance, MO 63341
    5001 Lily Ridge Ct, Defiance, MO 63341
    5001 Lily Ridge Ct, Defiance, MO 63341
    /5

    $279,900

    • Land
    • 5 Acres
    • $55,980 per Acre

    5001 Lily Ridge Ct, Defiance, MO 63341

    Four Luxurious home sites, on 5 acre lots. Sunset Estates in St. Charles County MO. Located in the heart of Defiance and wine country. Bring your own builder/plans and build your dream home on one of these premium secluded, all wooded lots. Homesites are located on a private street with cul-de-sac. Homeowners will enjoy the peace and quiet, along with privacy. County water and high-speed

    Bill McNair II First American Real Estate Co.

    5001 Lily Ridge Ct, Defiance, MO 63341
  • 449 Stones Throw Ct, Defiance, MO 63341
    449 Stones Throw Ct, Defiance, MO 63341
    449 Stones Throw Ct, Defiance, MO 63341
    /4

    $420,800

    • Land
    • 5.26 Acres
    • $80,000 per Acre

    449 Stones Throw Ct, Defiance, MO 63341

    Welcome to Callaway Lake Estates, an exclusive luxury subdivision nestled in the serene countryside of unincorporated Saint Charles County, Missouri. This prestigious community offers 108 breathtaking lots, ranging from 5 to 15 acres, providing the perfect canvas for your custom dream home. With a minimum build requirement of 2,400 sq. ft. and architectural approval, each estate combines elegance

    Toni Dillon Trophy Properties & Auction

    449 Stones Throw Ct, Defiance, MO 63341
  • 0 Defiance Rd Unit 22755774, Defiance, MO 63341
    0 Defiance Rd Unit 22755774, Defiance, MO 63341
    0 Defiance Rd Unit 22755774, Defiance, MO 63341
    /3

    $199,900

    • Land
    • 3.45 Acres
    • $57,942 per Acre

    0 Defiance Rd Unit 22755774, Defiance, MO 63341

    This expansive 3.45-acre lot is ideally situated in the heart of downtown Defiance, offering a rare combination of space and convenience. The property features a charming, rustic red barn that adds a touch of character and potential for various uses, from storage to creative projects. The ample size of the lot provides plenty of room for development, gardening, or outdoor activities. With its

    MO Realty MO Realty

    0 Defiance Rd Unit 22755774, Defiance, MO 63341
Missouri St. Charles County Defiance

Newest Listings for Sale in Defiance, MO

Frequently Asked Questions

What is the average home price in Defiance, MO?
Homes for sale in Defiance, MO have an average home price of $817,867.
Are home prices dropping in Defiance?
Yes, home prices in Defiance are down 1% in the last 12 months.
How many homes have sold over the last 12 months in Defiance, MO?
45 homes have sold in Defiance, MO over the last 12 months.
What are the most popular zip codes in Defiance, MO?
The most popular zip codes in Defiance, MO include 63341, 63073, 63348, 63332 and 63005.
How much do you need to make to afford a house in Defiance?
The median home price in Defiance is $659,900. If you put a 20% down payment of $132,000 and had a 30-year fixed mortgage with an interest rate of 6.01%, your estimated principal and interest payment would be $3,170 a month plus property taxes, HOA fees, home insurance, PMI, and utilities. Using the 28% rule, you would need to make at least $136K a year to afford the median home price in Defiance. Learn how much home you can afford with our Home Affordability Calculator.
How are the schools in Defiance, MO?
Defiance, MO has highly rated public and private schools. Some of the best schools in Defiance based on Niche Grades are Francis Howell High School, Daniel Boone Elementary School and Francis Howell Middle School. Browse all the schools in Defiance, MO to learn more.

Home Trends in Defiance, MO

On average, homes in Defiance, MO sell after 74 days on the market compared to the national average of 54 days. The median sale price for homes in Defiance, MO over the last 12 months is $580,000, down 8% from the median home sale price over the previous 12 months.

Housing Trends

Median Sale Price
$580,000
Median Single Family Sale Price
$595,000
Average Price Per Sq Ft
$221
Number of Homes for Sale
8
Last 12 months Home Sales
45
Months of Supply
2.10
Median List Price
$659,900
Median Change From 1st List Price
4%
Median Home Sale Price YoY Change
-8%
How to Buy a Home How to Finance a Home How to Sell a Home

Disclaimer: Certain information contained herein is derived from information provided by parties other than Homes.com. All information provided is deemed reliable, but is not guaranteed to be accurate and should be independently verified.

Homes.com Licensing Information

§ 442-H New York Standard Operating Procedures

New York Fair Housing Notice

TREC: Information about brokerage services, Consumer protection notice

California DRE #01937601

Contact Homes.com Brokerage

Copyright © 2026 CoStar Group