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Newest Homes for Sale in Defiance, MO

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  • 2461 Highway F, Defiance, MO 63341
    2461 Highway F, Defiance, MO 63341
    /2

    $485,000 Coming Soon

    • Land
    • 9.05 Acres
    • $53,591 per Acre

    2461 Highway F, Defiance, MO 63341

    This mostly level 9.05 Acres of land includes a well with a solar-powered pump and five frost-free spigots on the southeast side—perfect for gardens, orchards, or hobby farming. A gravel driveway has already been added along the south side for convenient access. Only a small portion of the front is in the 100-year floodplain, while the majority of the property sits outside of it, giving you

    Catherine Shaw-Connely Tom Shaw, REALTORS

    2461 Highway F, Defiance, MO 63341
  • 50 Sunfish Dr, Defiance, MO 63341
    50 Sunfish Dr, Defiance, MO 63341
    50 Sunfish Dr, Defiance, MO 63341
    /50

    $950,000 Coming Soon

    • 4 Beds
    • 4.5 Baths
    • 4,579 Sq Ft

    50 Sunfish Dr, Defiance, MO 63341

    Experience the best of Callaway Valley living—where privacy, luxury, and lifestyle align.Situated on a stunning 6-acre estate with coveted lake rights, this exceptional property offers a rare blend of space, serenity, and high-end living.The heart of the home is a chef’s dream kitchen, beautifully updated in 2022 with a 48” Wolf gas range with pot filler, Sub-Zero refrigerator, expansive

    Jessica Settlemoir Realty Shop

    50 Sunfish Dr, Defiance, MO 63341
  • 35 Greenview Dr, Defiance, MO 63341
    35 Greenview Dr, Defiance, MO 63341
    35 Greenview Dr, Defiance, MO 63341
    /5

    $675,000 Open Sun 1PM - 3PM

    • 4 Beds
    • 3.5 Baths
    • 3,831 Sq Ft

    35 Greenview Dr, Defiance, MO 63341

    Enjoy serene country living on 3+level, wooded acres in picturesque Defiance! This spacious 4-bedroom, 3.5-bath ranch offers an open floor plan with hardwood flooring throughout, fresh paint, and a new roof. The expansive kitchen features custom oak cabinetry, Corian countertops, center island with cooktop, double ovens, Sub-Zero refrigerator, built-in desk, and pantry—flowing seamlessly into a

    Victoria Meder Platinum Realty of St. Louis

    35 Greenview Dr, Defiance, MO 63341
  • 4 Cooper's Ct, Defiance, MO 63341
    4 Cooper's Ct, Defiance, MO 63341
    4 Cooper's Ct, Defiance, MO 63341
    /4

    $587,000

    • Land
    • 5.87 Acres
    • $100,000 per Acre

    4 Cooper's Ct, Defiance, MO 63341

    Nestled in the heart of St. Charles County near Defiance and New Melle, MO, Callaway Lake Estates offers a rare opportunity to build your dream home surrounded by natural beauty while remaining close to modern conveniences. This private community is designed for those seeking space, recreation, and long-term value. The development features 108 homesites, with 35 already sold in the first 18

    Toni Dillon Trophy Properties & Auction

    4 Cooper's Ct, Defiance, MO 63341
  • 12 Still Waters Ct, Defiance, MO 63341
    12 Still Waters Ct, Defiance, MO 63341
    12 Still Waters Ct, Defiance, MO 63341
    /4

    $350,000

    • Land
    • 5 Acres
    • $70,000 per Acre

    12 Still Waters Ct, Defiance, MO 63341

    Nestled in the heart of St. Charles County near Defiance and New Melle, MO, Callaway Lake Estates offers a rare opportunity to build your dream home surrounded by natural beauty while remaining close to modern conveniences. This private community is designed for those seeking space, recreation, and long-term value. The development features 108 homesites, with 35 already sold in the first 18

    Toni Dillon Trophy Properties & Auction

    12 Still Waters Ct, Defiance, MO 63341
  • 510 Callaway Estates Dr, Defiance, MO 63341
    510 Callaway Estates Dr, Defiance, MO 63341
    510 Callaway Estates Dr, Defiance, MO 63341
    /4

    $350,000

    • Land
    • 5 Acres
    • $70,000 per Acre

    510 Callaway Estates Dr, Defiance, MO 63341

    Nestled in the heart of St. Charles County near Defiance and New Melle, MO, Callaway Lake Estates offers a rare opportunity to build your dream home surrounded by natural beauty while remaining close to modern conveniences. This private community is designed for those seeking space, recreation, and long-term value. The development features 108 homesites, with 35 already sold in the first 18

    Toni Dillon Trophy Properties & Auction

    510 Callaway Estates Dr, Defiance, MO 63341
  • 3077 S Highway 94 (5 03+ - Acres), Defiance, MO 63341
    3077 S Highway 94 (5 03+ - Acres), Defiance, MO 63341
    3077 S Highway 94 (5 03+ - Acres), Defiance, MO 63341
    /19

    $325,000

    • Land
    • 5.03 Acres
    • $64,612 per Acre

    3077 S Highway 94 (5 03+ - Acres), Defiance, MO 63341

    5.03 acre homesite with exceptional Missouri River Valley views just outside the heart of Defiance. This scenic property offers a rare opportunity to build your home where the landscape opens to sweeping countryside views and beautiful sunrise exposure over the valley. The property features a PRIVATE Lane with direct access to Hwy 94, providing convenient access while maintaining a peaceful

    Meyer Auctions Meyer & Company Real Estate and Auctions

    3077 S Highway 94 (5 03+ - Acres), Defiance, MO 63341
  • 3840 Rooster Ridge Ln, Defiance, MO 63341
    3840 Rooster Ridge Ln, Defiance, MO 63341
    3840 Rooster Ridge Ln, Defiance, MO 63341
    /62

    $775,000

    • 3 Beds
    • 3.5 Baths
    • 5,601 Sq Ft

    3840 Rooster Ridge Ln, Defiance, MO 63341

    LOCATION is perfection! Travel down a paved road and arrive at your custom ranch home, with double garages, a finished basement, stunning seller/builder details with over 5,000 total finished SF! I need way more space here to describe all of the features. Large kitchen with second dining / living area arranged around the Buck stove fireplace. Brazilian cherry flooring, double wall ovens, long

    Agent Photo

    Hope Fick

    (636) 556-4474

    3840 Rooster Ridge Ln, Defiance, MO 63341
  • 115 Markham Trail Ln, Defiance, MO 63341
    115 Markham Trail Ln, Defiance, MO 63341
    115 Markham Trail Ln, Defiance, MO 63341
    /43

    $1,499,000

    • 4 Beds
    • 3.5 Baths
    • 4,461 Sq Ft

    115 Markham Trail Ln, Defiance, MO 63341

    Looking for the perfect multi-generational home or private in-law suite with its own entrance? This custom-built Lombardo Ranch on 5.44 acres checks every box. Thoughtfully designed with high-end upgrades throughout, this home blends style, comfort, and function in every detail.On the main level, you’ll find a chef’s kitchen featuring white custom cabinetry, quartz countertops, a striking

    Madison Lantz Berkshire Hathaway HomeServices Select Properties

    115 Markham Trail Ln, Defiance, MO 63341
  • 3077 S Missouri 94, Defiance, MO 63341
    3077 S Missouri 94, Defiance, MO 63341
    3077 S Missouri 94, Defiance, MO 63341
    /16

    $325,000

    • Land
    • 5.03 Acres
    • $64,612 per Acre

    3077 S Missouri 94, Defiance, MO 63341

    A truly rare opportunity to purchase 5 unrestricted acres with exceptional Missouri River Valley views. Ideally located within walking distance of the charming town of Defiance and the Katy Trail. Enjoy a 10-minute scenic drive to several county parks, the Weldon Spring Conservation Area, Missouri River access, and the Busch Shooting Range. Or unwind at one of the region’s many wineries, as this

    Sherry Ruyle Meyer & Company Real Estate

    3077 S Missouri 94, Defiance, MO 63341
  • 4075 Highway D, Defiance, MO 63341
    4075 Highway D, Defiance, MO 63341
    4075 Highway D, Defiance, MO 63341
    /30

    $949,900

    • 4 Beds
    • 5 Baths
    • 2,436 Sq Ft

    4075 Highway D, Defiance, MO 63341

    NOT IN A SUBDIVISION, NO INDENTURES OR RESTRICTIONS!!!! NEW ROOF.This is a must see!!! This beautifully updated, well maintained home with 3 beds, (3) full (2) 1/2 baths is on 10 flat acres. Primary bedroom has a bay window, separate shower/jacuzzi tub. Family room has a wood burning fireplace. Relax on the covered porch that overlooks a water feature and the lake. Kitchen has granite

    John Shaw Tom Shaw, REALTORS

    4075 Highway D, Defiance, MO 63341
  • 2 Woodridge Dr, Defiance, MO 63341
    2 Woodridge Dr, Defiance, MO 63341
    2 Woodridge Dr, Defiance, MO 63341
    /91

    $785,000

    • 4 Beds
    • 3.5 Baths
    • 4,564 Sq Ft

    2 Woodridge Dr, Defiance, MO 63341

    Spacious ranch home on 3 acres in one of the most beautiful settings in St. Charles County. Welcome home to picturesque rustic hardwood floors, a spacious country kitchen, large windows, vaulted ceilings, and TWO cozy fireplaces. The front, back, and side yards boast lovely mature trees placed perfectly to enhance the view and privacy. The pool (complete with a waterfall, salt water, and heater)

    Kathleen Helbig EXP Realty, LLC

    2 Woodridge Dr, Defiance, MO 63341
  • 180 Steeple Point Dr Lot #7 Dr, Defiance, MO 63341
    180 Steeple Point Dr Lot #7 Dr, Defiance, MO 63341
    180 Steeple Point Dr Lot #7 Dr, Defiance, MO 63341
    /4

    $151,000

    • Land
    • 5.03 Acres
    • $30,020 per Acre

    180 Steeple Point Dr Lot #7 Dr, Defiance, MO 63341

    Awesome lot available in a rural subdivision

    Dan Lauderdale Lauderdale Realty

    180 Steeple Point Dr Lot #7 Dr, Defiance, MO 63341
  • 130 Steeple Point Dr Lot #12 Dr, Defiance, MO 63341
    130 Steeple Point Dr Lot #12 Dr, Defiance, MO 63341
    130 Steeple Point Dr Lot #12 Dr, Defiance, MO 63341
    /9

    $151,000

    • Land
    • 5.05 Acres
    • $29,901 per Acre

    130 Steeple Point Dr Lot #12 Dr, Defiance, MO 63341

    Great Building Lot. Schedule an appointment and view this property today.

    Dan Lauderdale Lauderdale Realty

    130 Steeple Point Dr Lot #12 Dr, Defiance, MO 63341
  • 110 Steeple Point Dr Lot # 14 Dr, Defiance, MO 63341
    110 Steeple Point Dr Lot # 14 Dr, Defiance, MO 63341
    /2

    $238,900

    • Land
    • 8.89 Acres
    • $26,873 per Acre

    110 Steeple Point Dr Lot # 14 Dr, Defiance, MO 63341

    WOW, nearly 9 acres for under $250,000. Schedule an appointment and view this lot today.

    Dan Lauderdale Lauderdale Realty

    110 Steeple Point Dr Lot # 14 Dr, Defiance, MO 63341
  • 150 Steeple Point Dr Lot #10 Dr, Defiance, MO 63341
    150 Steeple Point Dr Lot #10 Dr, Defiance, MO 63341
    150 Steeple Point Dr Lot #10 Dr, Defiance, MO 63341
    /4

    $154,000

    • Land
    • 5.13 Acres
    • $30,019 per Acre

    150 Steeple Point Dr Lot #10 Dr, Defiance, MO 63341

    Gorgeous Lot in Steeple Point. Great views and quite living.

    Dan Lauderdale Lauderdale Realty

    150 Steeple Point Dr Lot #10 Dr, Defiance, MO 63341
  • 190 Steeple Point Dr Lot #6 Dr, Defiance, MO 63341
    190 Steeple Point Dr Lot #6 Dr, Defiance, MO 63341
    /2

    $290,000

    • Land
    • 10.72 Acres
    • $27,052 per Acre

    190 Steeple Point Dr Lot #6 Dr, Defiance, MO 63341

    Great home site in a rural setting.

    Dan Lauderdale Lauderdale Realty

    190 Steeple Point Dr Lot #6 Dr, Defiance, MO 63341
  • 120 Steeple Point Dr Lot #13 Dr, Defiance, MO 63341
    120 Steeple Point Dr Lot #13 Dr, Defiance, MO 63341
    /2

    $152,000

    • Land
    • 5.06 Acres
    • $30,040 per Acre

    120 Steeple Point Dr Lot #13 Dr, Defiance, MO 63341

    Another Great Lot in the Steeple Point Subdivision. Schedule your appointment to view today.

    Dan Lauderdale Lauderdale Realty

    120 Steeple Point Dr Lot #13 Dr, Defiance, MO 63341
  • 160 Steeple Point Dr Lot #9 Dr, Defiance, MO 63341
    160 Steeple Point Dr Lot #9 Dr, Defiance, MO 63341
    160 Steeple Point Dr Lot #9 Dr, Defiance, MO 63341
    /12

    $155,000

    • Land
    • 5.17 Acres
    • $29,981 per Acre

    160 Steeple Point Dr Lot #9 Dr, Defiance, MO 63341

    Dan Lauderdale Lauderdale Realty

    160 Steeple Point Dr Lot #9 Dr, Defiance, MO 63341
  • 1330 Lake Hollow Dr, Defiance, MO 63341
    1330 Lake Hollow Dr, Defiance, MO 63341
    1330 Lake Hollow Dr, Defiance, MO 63341
    /47

    $649,900

    • 4 Beds
    • 2.5 Baths
    • 2,556 Sq Ft

    1330 Lake Hollow Dr, Defiance, MO 63341

    Enjoy the serenity of your own private retreat, surrounded by trees and nature while still being just minutes from shopping, dining, and entertainment. Inside, the stunning kitchen is a true showpiece—featuring quartz countertops, cherry cabinetry, stainless steel appliances, a massive island, and a spacious walk-in pantry. The main level shines with new 5” wide wood-plank luxury vinyl flooring,

    Suzanne Matyiko ReeceNichols Real Estate

    1330 Lake Hollow Dr, Defiance, MO 63341
  • 353 Callaway Ridge Dr, Defiance, MO 63341
    353 Callaway Ridge Dr, Defiance, MO 63341
    353 Callaway Ridge Dr, Defiance, MO 63341
    /67

    $2,750,000

    • 3 Beds
    • 4.5 Baths
    • 4,037 Sq Ft

    353 Callaway Ridge Dr, Defiance, MO 63341

    Experience the ultimate in privacy and natural beauty with this stunning custom waterfront property nestled on 37+ mostly wooded acres fronting the serene waters of Callaway Valley Lake. Crafted with exceptional attention to detail, this one-of-a-kind property showcases rich woodwork and impeccable craftsmanship throughout. Highlighted by a grand wood-paneled ceiling with softly arched beams, and

    Kelly Beanblossom-Schlake Blondin Group, Inc

    353 Callaway Ridge Dr, Defiance, MO 63341
  • 404 Stones Throw Ct, Defiance, MO 63341
    404 Stones Throw Ct, Defiance, MO 63341
    404 Stones Throw Ct, Defiance, MO 63341
    /23

    $300,000

    • Land
    • 5.01 Acres
    • $59,907 per Acre

    404 Stones Throw Ct, Defiance, MO 63341

    Beautiful 5-acre building lot located in the highly sought-after gated community of Callaway Lake Estates! Bring your builder and design the home of your dreams while adhering to community building restrictions that help preserve the neighborhood’s character and value. Enjoy access to the 168-acre Callaway Lake, perfect for fishing, boating, and relaxing by the water. This prime lot is within the

    Tim Phillips MO Realty

    404 Stones Throw Ct, Defiance, MO 63341
  • 170 Blue Sky, Defiance, MO 63341
    170 Blue Sky, Defiance, MO 63341
    170 Blue Sky, Defiance, MO 63341
    /98

    $1,389,000 Open Sun 1PM - 3PM

    • 5 Beds
    • 5.5 Baths
    • 5,504 Sq Ft

    170 Blue Sky, Defiance, MO 63341

    Brand new custom-built home on 3+ wooded acres in Kohler Estates subdivision. Features 4 bedrooms and 5 1/2 baths, a oversized 4 car garage with stair access to basement, a Great Room with a stone gas fireplace, with custom bookshelves, Gourmet kitchen offers custom cabinetry with quartz countertops, tile backsplash, and a complete appliance package, and walk-in pantry with custom shelving.

    Chris Dawson Orenda Real Estate Services

    170 Blue Sky, Defiance, MO 63341
  • 5011 Lily Ridge, Defiance, MO 63341
    5011 Lily Ridge, Defiance, MO 63341
    5011 Lily Ridge, Defiance, MO 63341
    /4

    $279,900

    • Land
    • 5 Acres
    • $55,980 per Acre

    5011 Lily Ridge, Defiance, MO 63341

    Sunset Estates in St. Charles County MO. Four Luxurious home sites, on 5 acre lots. Located in the heart of Defiance and wine country. Bring your own builder/plans and build your dream home on one of these premium secluded, all wooded lots. Homesites are located on a private street with cul-de-sac. Homeowners will enjoy the peace and quiet, along with privacy. County water and high-speed

    Bill McNair II First American Real Estate Co.

    5011 Lily Ridge, Defiance, MO 63341
  • 5001 Lily Ridge Ct, Defiance, MO 63341
    5001 Lily Ridge Ct, Defiance, MO 63341
    5001 Lily Ridge Ct, Defiance, MO 63341
    /5

    $279,900

    • Land
    • 5 Acres
    • $55,980 per Acre

    5001 Lily Ridge Ct, Defiance, MO 63341

    Four Luxurious home sites, on 5 acre lots. Sunset Estates in St. Charles County MO. Located in the heart of Defiance and wine country. Bring your own builder/plans and build your dream home on one of these premium secluded, all wooded lots. Homesites are located on a private street with cul-de-sac. Homeowners will enjoy the peace and quiet, along with privacy. County water and high-speed

    Bill McNair II First American Real Estate Co.

    5001 Lily Ridge Ct, Defiance, MO 63341
  • 0 Defiance Rd Unit 22755774, Defiance, MO 63341
    0 Defiance Rd Unit 22755774, Defiance, MO 63341
    0 Defiance Rd Unit 22755774, Defiance, MO 63341
    /3

    $199,900

    • Land
    • 3.45 Acres
    • $57,942 per Acre

    0 Defiance Rd Unit 22755774, Defiance, MO 63341

    This expansive 3.45-acre lot is ideally situated in the heart of downtown Defiance, offering a rare combination of space and convenience. The property features a charming, rustic red barn that adds a touch of character and potential for various uses, from storage to creative projects. The ample size of the lot provides plenty of room for development, gardening, or outdoor activities. With its

    MO Realty MO Realty

    0 Defiance Rd Unit 22755774, Defiance, MO 63341
Missouri St. Charles County Defiance

Newest Listings for Sale in Defiance, MO

Frequently Asked Questions

What is the average home price in Defiance, MO?
Homes for sale in Defiance, MO have an average home price of $849,727.
Are home prices dropping in Defiance?
Yes, home prices in Defiance are down 3% in the last 12 months.
How many homes have sold over the last 12 months in Defiance, MO?
42 homes have sold in Defiance, MO over the last 12 months.
What are the most popular zip codes in Defiance, MO?
The most popular zip codes in Defiance, MO include 63341, 63073, 63005, 63348 and 63332.
How much do you need to make to afford a house in Defiance?
The median home price in Defiance is $749,000. If you put a 20% down payment of $149,800 and had a 30-year fixed mortgage with an interest rate of 6.37%, your estimated principal and interest payment would be $3,740 a month plus property taxes, HOA fees, home insurance, PMI, and utilities. Using the 28% rule, you would need to make at least $160K a year to afford the median home price in Defiance. Learn how much home you can afford with our Home Affordability Calculator.
How are the schools in Defiance, MO?
Defiance, MO has highly rated public and private schools. Some of the best schools in Defiance based on Niche Grades are Francis Howell High School, Daniel Boone Elementary School and Francis Howell Middle School. Browse all the schools in Defiance, MO to learn more.

Home Trends in Defiance, MO

On average, homes in Defiance, MO sell after 54 days on the market compared to the national average of 55 days. The median sale price for homes in Defiance, MO over the last 12 months is $615,000, down 2% from the median home sale price over the previous 12 months.

Housing Trends

Median Sale Price
$615,000
Median Single Family Sale Price
$660,000
Average Price Per Sq Ft
$207
Number of Homes for Sale
10
Last 12 months Home Sales
42
Months of Supply
2.90
Median List Price
$749,000
Median Change From 1st List Price
5%
Median Home Sale Price YoY Change
-2%
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