17

Defiance, MO Homes for Sale under $600,000

Section Image
  • 3077 S Missouri 94, Defiance, MO 63341
    3077 S Missouri 94, Defiance, MO 63341
    3077 S Missouri 94, Defiance, MO 63341
    /25

    $305,000

    • Land
    • 5.03 Acres
    • $60,636 per Acre

    3077 S Missouri 94, Defiance, MO 63341

    Rare opportunity to own 5.03 acres overlooking the Missouri River Valley just outside the heart of Defiance. Enjoy sweeping sunrise views, a private setting, and plenty of usable yard space for a custom home, outdoor living, gardens, or additional structures. A private lane provides direct access to Hwy 94 while maintaining a peaceful setting. The existing clearing offers an excellent homesite

    Meyer Auctions Meyer & Company Real Estate and Auctions

    3077 S Missouri 94, Defiance, MO 63341
  • 28 Meditation Way, Defiance, MO 63341
    28 Meditation Way, Defiance, MO 63341
    28 Meditation Way, Defiance, MO 63341
    /4

    $334,200

    Under Contract
    • Land
    • 5.57 Acres
    • $60,000 per Acre

    28 Meditation Way, Defiance, MO 63341

    Nestled in the heart of St. Charles County in Defiance and near New Melle, MO, Callaway Lake Estates offers a rare opportunity to build your dream home surrounded by natural beauty while remaining close to modern conveniences. This private community is designed for those seeking space, recreation, and long-term value. The development features 108 homesites, with 40 lots already sold in the first

    Toni Dillon Trophy Properties & Auction

    28 Meditation Way, Defiance, MO 63341
  • 0 Defiance Rd Unit MIS26025560, Defiance, MO 63341
    0 Defiance Rd Unit MIS26025560, Defiance, MO 63341
    /2

    $375,000

    $50K PRICE DROP
    • Land
    • 8.5 Acres
    • $44,118 per Acre

    0 Defiance Rd Unit MIS26025560, Defiance, MO 63341

    8.5+/- Fabulous acres that offer a combination of open land, level to rolling hills, wooded land & access to a shared pond. Rare opportunity to own this beautiful, very scenic acreage. The perfect place for an equestrian homestead, a country estate, contemporary farmhouse or your DREAM development. This acreage offers seclusion, country style living, with an abundant wildlife habitat for the avid

    Catherine Shaw-Connely Tom Shaw, REALTORS

    0 Defiance Rd Unit MIS26025560, Defiance, MO 63341
  • 4 Cooper's Ct, Defiance, MO 63341
    4 Cooper's Ct, Defiance, MO 63341
    4 Cooper's Ct, Defiance, MO 63341
    /4

    $587,000

    • Land
    • 5.87 Acres
    • $100,000 per Acre

    4 Cooper's Ct, Defiance, MO 63341

    Nestled in the heart of St. Charles County near Defiance and New Melle, MO, Callaway Lake Estates offers a rare opportunity to build your dream home surrounded by natural beauty while remaining close to modern conveniences. This private community is designed for those seeking space, recreation, and long-term value. The development features 108 homesites, with 35 already sold in the first 18

    Toni Dillon Trophy Properties & Auction

    4 Cooper's Ct, Defiance, MO 63341
  • 36 Meditation Way, Defiance, MO 63341
    36 Meditation Way, Defiance, MO 63341
    36 Meditation Way, Defiance, MO 63341
    /4

    $318,600

    Under Contract
    • Land
    • 5.31 Acres
    • $60,000 per Acre

    36 Meditation Way, Defiance, MO 63341

    Nestled in the heart of St. Charles County in Defiance and near New Melle, MO, Callaway Lake Estates offers a rare opportunity to build your dream home surrounded by natural beauty while remaining close to modern conveniences. This private community is designed for those seeking space, recreation, and long-term value. The development features 108 homesites, with 40 lots already sold in the first

    Toni Dillon Trophy Properties & Auction

    36 Meditation Way, Defiance, MO 63341
  • 2461 Highway F, Defiance, MO 63341
    2461 Highway F, Defiance, MO 63341
    /2

    $449,900

    $35K PRICE DROP
    • Land
    • 9.05 Acres
    • $49,713 per Acre

    2461 Highway F, Defiance, MO 63341

    This mostly level 9.05 Acres of land includes a well with a solar-powered pump and five frost-free spigots on the southeast side—perfect for gardens, orchards, or hobby farming. A gravel driveway has already been added along the south side for convenient access. Only a small portion of the front is in the 100-year floodplain, while the majority of the property sits outside of it, giving you

    Catherine Shaw-Connely Tom Shaw, REALTORS

    2461 Highway F, Defiance, MO 63341
  • 517 Callaway Estates Dr, Defiance, MO 63341
    517 Callaway Estates Dr, Defiance, MO 63341
    517 Callaway Estates Dr, Defiance, MO 63341
    /4

    $350,000

    • Land
    • 5 Acres
    • $70,000 per Acre

    517 Callaway Estates Dr, Defiance, MO 63341

    Nestled in the heart of St. Charles County near Defiance and New Melle, MO, Callaway Lake Estates offers a rare opportunity to build your dream home surrounded by natural beauty while remaining close to modern conveniences. This private community is designed for those seeking space, recreation, and long-term value. The development features 108 homesites, with 35 already sold in the first 18

    Stephen Kaiser Trophy Properties & Auction

    517 Callaway Estates Dr, Defiance, MO 63341
  • 513 Callaway Estates Dr, Defiance, MO 63341
    513 Callaway Estates Dr, Defiance, MO 63341
    513 Callaway Estates Dr, Defiance, MO 63341
    /4

    $350,000

    Under Contract
    • Land
    • 5 Acres
    • $70,000 per Acre

    513 Callaway Estates Dr, Defiance, MO 63341

    Nestled in the heart of St. Charles County near Defiance and New Melle, MO, Callaway Lake Estates offers a rare opportunity to build your dream home surrounded by natural beauty while remaining close to modern conveniences. This private community is designed for those seeking space, recreation, and long-term value. The development features 108 homesites, with 40 already sold in the first 18

    Toni Dillon Trophy Properties & Auction

    513 Callaway Estates Dr, Defiance, MO 63341
  • 503 Callaway Estates Dr, Defiance, MO 63341
    503 Callaway Estates Dr, Defiance, MO 63341
    503 Callaway Estates Dr, Defiance, MO 63341
    /4

    $350,000

    Under Contract
    • Land
    • 5 Acres
    • $70,000 per Acre

    503 Callaway Estates Dr, Defiance, MO 63341

    Nestled in the heart of St. Charles County near Defiance and New Melle, MO, Callaway Lake Estates offers a rare opportunity to build your dream home surrounded by natural beauty while remaining close to modern conveniences. This private community is designed for those seeking space, recreation, and long-term value. The development features 108 homesites, with 40 already sold in the first 18

    Toni Dillon Trophy Properties & Auction

    503 Callaway Estates Dr, Defiance, MO 63341
  • 3877 Highway D, Defiance, MO 63341
    3877 Highway D, Defiance, MO 63341
    3877 Highway D, Defiance, MO 63341
    /37

    $520,000

    $29K PRICE DROP
    • 3 Beds
    • 2 Baths
    • 1,600 Sq Ft

    3877 Highway D, Defiance, MO 63341

    Spacious ranch on 6 gorgeous acres conveniently located just minutes from wineries, schools, shopping and highways! This charming 3 bedroom, 2 bath home comes complete with main floor laundry, full, unfinished basement, and a primary bedroom with walk-in closet and ensuite bath. Besides the 2-car attached garage, there is a 28’x60’ insulated metal outbuilding with concrete floor, electric and 220

    Sherry Raleigh-Adams Wolfe Realty

    3877 Highway D, Defiance, MO 63341
  • 2540 S Highway 94, Defiance, MO 63341
    2540 S Highway 94, Defiance, MO 63341
    2540 S Highway 94, Defiance, MO 63341
    /10

    $499,900

    Under Contract
    • 3 Beds
    • 2.5 Baths
    • 1,978 Sq Ft

    2540 S Highway 94, Defiance, MO 63341

    Country living on 5.21+/- level STUNNING acres in unincorporated Defiance! A tree lined driveway leads to a CHARMING, RANCH home with 3 bedrooms, 2.5 baths & 1,978+/- SqFt of living space that offers an AWESOME, 30’ x 24’, 2-car, detached garage & shed. Partially covered front porch greets you as you step inside the entry foyer. Step down, living room boasts a floor-to-ceiling brick wood burning

    Catherine Shaw-Connely Tom Shaw, REALTORS

    2540 S Highway 94, Defiance, MO 63341
  • 8 Whippoorwill Ct, Defiance, MO 63341
    8 Whippoorwill Ct, Defiance, MO 63341
    8 Whippoorwill Ct, Defiance, MO 63341
    /76

    $579,900

    $40K PRICE DROP
    • 4 Beds
    • 3.5 Baths
    • 3,057 Sq Ft

    8 Whippoorwill Ct, Defiance, MO 63341

    Escape to your own private retreat with this stunning log home nestled on 3 ACRES, where peaceful country living meets modern comfort. Surrounded by mature trees and breathtaking natural beauty, you'll enjoy the serenity of nature while remaining just 15 minutes from Highway 40 and Highway 70, offering the perfect balance of privacy and convenience. Enjoy the view from either the fully covered

    Jennifer Bommarito Fox & Riley Real Estate

    8 Whippoorwill Ct, Defiance, MO 63341
  • 1451 Highway F, Defiance, MO 63341
    1451 Highway F, Defiance, MO 63341
    1451 Highway F, Defiance, MO 63341
    /43

    $599,900

    $100K PRICE DROP Pending
    • 3 Beds
    • 2.5 Baths
    • 1,944 Sq Ft

    1451 Highway F, Defiance, MO 63341

    Rarely does an opportunity like this come available in Defiance! Located in the beautiful Femme Osage valley, nestled on 9+ picturesque acres, this 3 bed, 2.5 home offers the perfect blend of privacy, space, and comfort. The setting is rural but convenient to highway 64/40, Chesterfield, Wentzville, and Francis Howell schools. Step inside to find hardwood floors throughout the main level, leading

    Matthew Lauman Magnolia Real Estate

    1451 Highway F, Defiance, MO 63341
  • 510 Callaway Estates Dr, Defiance, MO 63341
    510 Callaway Estates Dr, Defiance, MO 63341
    510 Callaway Estates Dr, Defiance, MO 63341
    /4

    $350,000

    • Land
    • 5 Acres
    • $70,000 per Acre

    510 Callaway Estates Dr, Defiance, MO 63341

    Nestled in the heart of St. Charles County near Defiance and New Melle, MO, Callaway Lake Estates offers a rare opportunity to build your dream home surrounded by natural beauty while remaining close to modern conveniences. This private community is designed for those seeking space, recreation, and long-term value. The development features 108 homesites, with 35 already sold in the first 18

    Toni Dillon Trophy Properties & Auction

    510 Callaway Estates Dr, Defiance, MO 63341
  • 9 Wilderness Ln, Defiance, MO 63341
    9 Wilderness Ln, Defiance, MO 63341
    9 Wilderness Ln, Defiance, MO 63341
    /54

    $450,000

    Pending
    • 3 Beds
    • 2.5 Baths
    • 1,762 Sq Ft

    9 Wilderness Ln, Defiance, MO 63341

    Welcome to this beautiful 2-story home nestled on 3.9 private acres in the heart of Defiance. Offering 3 bedrooms and 2.5 baths, this property combines peaceful country living with timeless charm.The bright, inviting kitchen features white cabinetry, a center island with an electric cooktop, hardwood floors, and plenty of workspace for cooking and entertaining. The convenient main floor

    Jennifer Gentry Coldwell Banker Realty - Gundaker

    9 Wilderness Ln, Defiance, MO 63341
  • 449 Stones Throw Ct, Defiance, MO 63341
    449 Stones Throw Ct, Defiance, MO 63341
    449 Stones Throw Ct, Defiance, MO 63341
    /4

    $420,800

    • Land
    • 5.26 Acres
    • $80,055 per Acre

    449 Stones Throw Ct, Defiance, MO 63341

    Nestled in the heart of St. Charles County near Defiance and New Melle, MO, Callaway Lake Estates offers a rare opportunity to build your dream home surrounded by natural beauty while remaining close to modern conveniences. This private community is designed for those seeking space, recreation, and long-term value. The development features 108 homesites, with 35 already sold in the first 18

    Stephen Kaiser Trophy Properties & Auction

    449 Stones Throw Ct, Defiance, MO 63341
  • 3901 Highway D, Defiance, MO 63341
    3901 Highway D, Defiance, MO 63341
    3901 Highway D, Defiance, MO 63341
    /32

    $364,950

    $15K PRICE DROP
    • 3 Beds
    • 1 Bath
    • 1,296 Sq Ft

    3901 Highway D, Defiance, MO 63341

    Ranch style, full brick home situated on 4.6 acres with an attached one car garage. The home has 3 bedrooms, 1 bath, 1296 square feet, some hardwood floors, and a full basement situated on a fairly level lot. Some photos are virtually staged.

    Michelle Syberg Mid America Property Partners

    3901 Highway D, Defiance, MO 63341
Missouri St. Charles County

Real Estate & Homes in Defiance, MO under $600,000

Home Prices in Defiance, MO

The median home sale price in Defiance, MO is $685,000, up 4% year-over-year. Homes in Defiance sell in 52 days on average, compared to the national average of 55 days.

Home Price Trends

Median Sale Price
$685,000
Median Single Family Sale Price
$672,500
Median 2 Bedroom Sale Price
$495,000
Average Price Per Sq Ft
$235
Number of Homes for Sale
13
Last 12 months Home Sales
53
Months of Supply
2.90
Median List Price
$709,900
Median Change From 1st List Price
2%
Median Home Sale Price YoY Change
4%
How to Buy a Home How to Finance a Home How to Sell a Home

Disclaimer: Certain information contained herein is derived from information provided by parties other than Homes.com. All information provided is deemed reliable, but is not guaranteed to be accurate and should be independently verified.

Homes.com Licensing Information

§ 442-H New York Standard Operating Procedures

New York Fair Housing Notice

TREC: Information about brokerage services, Consumer protection notice

California DRE #01937601

Contact Homes.com Brokerage

Copyright © 2026 CoStar Group