Florence, SC Homes for Sale with Acreage

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  /14

  $1,644,000

  • 10 Beds
  • 5 Baths
  • 14,576 Sq Ft

  200 Hudson Dr, Florence, SC 29506

  **Investment Opportunity -Charming Duplex Apartment Complex in Florence, SC**Discover an exceptional investment opportunity with this well-maintained apartment complex featuring 8 spacious duplexes, each designed for comfortable living. Located in the heart of Florence, SC, this property is an investor's dream, offering significant cash flow potential and strong returns.Each duplex consists of 2

  

  Tammy Lyles

  SM Realty & Associates LLC

  (843) 919-4679

  200 Hudson Dr, Florence, SC 29506
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  Explore Florence

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  /2

  $399,900

  • Land
  • 1.38 Acres
  • $289,783 per Acre

  1521 2nd Loop Rd, Florence, SC 29505

  For sale a portion of lot located at 1521 2nd Loop Rd, approx 1.38 acres (lot is to the left side of the Carolina Trading Post. The actual address and TMS of the lot is TBD

  

  Chad Yates

  Assist 2 Sell, Buyers & Seller

  (843) 938-1717

  1521 2nd Loop Rd, Florence, SC 29505
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  /32

  $245,000

  • 3 Beds
  • 2 Baths
  • 1,650 Sq Ft

  226 S Wallace Rd, Florence, SC 29506

  What a fantastic property with tons of updates—and boy, does it look good! This 3-bedroom, 2-bath home sits on a beautiful one-acre lot and has been cared for with impressive improvements. In 2025, the entire home was freshly painted, including walls, trim & ceilings and a breakfast bar was added in the kitchen. In 2024, new septic field lines were installed, a moisture barrier was added and a

  

  Tom Snyder

  ERA Leatherman Realty, Inc.

  (843) 699-8488

  226 S Wallace Rd, Florence, SC 29506
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  /14

  $559,900

  • 4 Beds
  • 3 Baths
  • 2,839 Sq Ft

  3703 State Road S-21-1389, Florence, SC 29501

  Discover refined luxury in this Modern farmhouse design, this home is to-be-built currently in the foundation phase. This plan features 2839sqft with 4 bedrooms, 3 bathrooms and a 2 car garage. This well appointed home will be situated on a 1.11 acre corner lot in Colonial Heights Subdivision in West Florence. There are many features and upgrades planned for the interior of this home from

  

  Chad Yates

  Assist 2 Sell, Buyers & Seller

  (843) 400-2112

  3703 State Road S-21-1389, Florence, SC 29501
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  /13

  $59,700

  • Land
  • 1.7 Acres
  • $35,118 per Acre

  3141 Woodside Dr, Florence, SC 29541

  Discover the perfect opportunity to build your dream home on this spacious 1.7-acre residential lot located in the desirable Millwood Run subdivision. This lot offers a serene and picturesque setting, backing up to the tranquil Alligator Branch, providing a peaceful backdrop for your future residence.Contact your agent for more information or to schedule a viewing!

  

  Robricco Porter

  Coldwell Banker McMillan and Associates

  (843) 612-1932

  3141 Woodside Dr, Florence, SC 29541
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  /5

  $799,000 New Construction

  • 5 Beds
  • 3.5 Baths
  • 3,883 Sq Ft

  928 Barclay Dr, Florence, SC 29501

  Luxury New Construction on 1.06 Acres! Experience the perfect blend of elegance and space in this stunning new construction brick home nestled on over an acre. Boasting 5 large bedrooms, 3 full bathrooms, and a convenient half bath, this residence offers luxurious living at its finest. The gourmet eat-in kitchen features a spacious island, stainless steel appliances, and quartz countertops —

  

  Crystal White Stroud

  My Real Estate Group,LLC

  (854) 204-4521

  928 Barclay Dr, Florence, SC 29501
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  /22

  $572,000

  • Land
  • 97.83 Acres
  • $5,847 per Acre

  Sugar Hill Fox Rd, Florence, SC 29505

  97+/- acre tract located in Pamplico, SC - Near Florence, SC! Being part of Sugar Hill Fox Pen, this property is partially fenced. Located at the front of the property is a small building that has water and power. Equipped with a mixture hardwoods and pines, this a great for the avid hunter. There is a small branch at the rear of the property that has the potential to make a great duck hunting

  Fred Chandler

  Sugar Hill Fox Rd, Florence, SC 29505
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  /46

  $389,900

  • 5 Beds
  • 3 Baths
  • 3,563 Sq Ft

  6431 E Old Marion Hwy, Florence, SC 29506

  Spacious 5-bedroom, 3-full-bath home on a generous 1-acre lot, perfectly situated in Florence, SC, just minutes from Francis Marion University, Buc-ee’s, and I-95 for convenient access to education, shopping, and travel. This stunning residence boasts a first-floor master suite and large, airy rooms throughout, offering ample space for comfortable living. Featuring a brand-new HVAC system for

  Samuel Fryer Drayton Realty Group

  6431 E Old Marion Hwy, Florence, SC 29506
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  /56

  $447,400

  • 5 Beds
  • 4 Baths
  • 3,338 Sq Ft

  4531 E National Cemetery Rd, Florence, SC 29506

  Charming Country Brick Home on 4 Acres with Pond. This spacious 5-bedroom, 4-bath home offers the perfect blend of country charm and modern comfort. Set on 4 picturesque acres with a serene pond, the brick residence features a freshly painted interior, stainless steel bathrooms, and a main-level owner’s suite. Enjoy peaceful living with plenty of room to roam—ideal for those seeking privacy and

  Ashley Drayton Drayton Realty Group

  4531 E National Cemetery Rd, Florence, SC 29506
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  /72

  $619,900

  • 7 Beds
  • 4.5 Baths
  • 6,276 Sq Ft

  1602 Cherokee Rd, Florence, SC 29501

  This spacious property offers a 5-bedroom, 3.5-bathroom main house with 4,676 sqft of living space, situated on 1.63 acres. The home features two full kitchens, perfect for multi-functional use, including a large, updated kitchen with a 4'x6' island, granite countertops, and a metal backsplash. Hardwood floors throughout the downstairs, dental crown molding, and a cozy family room with a gas log

  Tom Langan exp Realty Greyfeather Group

  1602 Cherokee Rd, Florence, SC 29501
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  /57

  $594,000

  • 3 Beds
  • 2 Baths
  • 3,706 Sq Ft

  4835 Willow Creek Rd, Florence, SC 29505

  Welcome to a truly unique country estate where historic charm meets modern amenities. Set on three picturesque acres, this exceptional property features a beautifully preserved main house built in 1880, offering timeless character and warmth throughout. Thoughtful updates have been seamlessly integrated, creating a comfortable and inviting home that honors its heritage. In addition to the main

  Steven Ateyeh EXP Realty LLC

  4835 Willow Creek Rd, Florence, SC 29505
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  /39

  $535,000

  • 3 Beds
  • 2 Baths
  • 1,352 Sq Ft

  3101 Willow Creek Rd, Florence, SC 29505

  For all Equine Lovers this is it: 19 Acres with a 5,300 square foot 18 stall horse barn, wash rack, 2 tack rooms and office with a full bath. 2 acre stocked pond; 53 x 40 pole shed. Dog pin. This is truly a special property. Nice home on front of property. So, a place for your horses, dogs, fish, equipment and people. Home can be split off and sold separately from land or vice versa.

  Joe McMillan C/B McMillan and Assoc.

  3101 Willow Creek Rd, Florence, SC 29505
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  /30

  $449,900

  • 3 Beds
  • 1 Bath
  • 1,316 Sq Ft

  130 N Mustang Rd, Florence, SC 29506

  2 Brick Ranch Homes---1) Home 3/1 Super Nice inside & 1 - Brick Ranch Home 3/2 coming available soon 1 -14x60 Singlewide Mastercraft All OF THIS IS A GREAT INVESTMENT PROPERTY 1-Double Wide 24x44 Mansion M 1n Garage Apartment 1 bedroom 1 bath den & kitchen & Garage 1 Rented Mobile Home Lot 1Tiny House MH 12x34 AHOY

  Jane Singleton Coldwell Banker McMillan and Associates

  130 N Mustang Rd, Florence, SC 29506
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  /56

  $659,900 New Construction

  • 4 Beds
  • 3.5 Baths
  • 3,328 Sq Ft

  4540 Tightrope Dr, Florence, SC 29501

  Welcome to Plum's Place! This stunning new construction home by Bean Builders LLC, situated on 2.70 acres in a beautiful setting. With 3,328 square feet, this thoughtfully designed residence offers the perfect combination of style, comfort, and functionality. Step inside to find an open and inviting floor plan featuring 4 spacious bedrooms and 3.5 bathrooms. A dedicated home office makes working

  Natasha Byrd House of Real Estate

  4540 Tightrope Dr, Florence, SC 29501
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  /5

  $120,000

  • Land
  • 5.17 Acres
  • $23,211 per Acre

  TBD E National Cemetary Rd, Florence, SC 29506

  5.17 Acres in Growing Florence Area Opportunity awaits with this 5.17-acre tract in the rapidly developing part of Florence. Surrounded by new construction, this property is ideal for building your dream home, investing, or future development. Conveniently located near schools, shopping, and major highways—offering both privacy and potential.

  Sydney Sweeney Tru Vision Realty

  TBD E National Cemetary Rd, Florence, SC 29506
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  /9

  $187,500

  • Land
  • 10.54 Acres
  • $17,789 per Acre

  10.5 Acres Leigh Ln, Florence, SC 29505

  This 10.5-acre wooded tract is tucked away at the back of Tara Village in South Florence, offering both privacy and potential. The property has deeded access through Aunt Prissey Court and Leigh Lane, giving it convenient entry points. It is zoned rural residential in the county, but right next door the city limits bring water and sewer service to the surrounding homes—making this a property with

  Brian Rodgers Northgroup Real Estate Llc

  10.5 Acres Leigh Ln, Florence, SC 29505
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  /13

  $265,000

  • Land
  • 6.54 Acres
  • $40,520 per Acre

  6.54 Acres-TBD Alligator Rd, Florence, SC 29501

  6.54 acres located on Alligator Road in Florence, SC! Looking for the perfect spot to build a home or open a business? Then take a look at this! Currently, unzoned, this 6.54 acres offers tons of potential. Located 15 minutes from downtown Florence and 10 minutes from Florence mall, this piece of land offers exclusion but close proximity to all things! There is a small adjoining pond at the rear

  Robert McCants Tidewater Properties

  6.54 Acres-TBD Alligator Rd, Florence, SC 29501
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  /42

  $239,900

  • 3 Beds
  • 2 Baths
  • 1,568 Sq Ft

  300 N Williamson Rd, Florence, SC 29506

  A renovated, move-in-ready home over an acre corner lot with no Homeowners Association (HOA). The property features three bedrooms and two full bathrooms. The relaxing, covered front porch surrounds plants and mulch with two doors that lead to the living room and den. Step inside to the freshly painted walls, crown molding, shoe molding, recessed lights, and new ceiling fans, complementing the

  Melissa Floyd Real Estate Direct

  300 N Williamson Rd, Florence, SC 29506
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  /36

  $329,000

  • 3 Beds
  • 2.5 Baths
  • 3,210 Sq Ft

  123 Timberlake Dr, Florence, SC 29501

  Nestled in the beloved Palmetto Shores community and conveniently located between Florence, SC and Darlington, SC this home is situated on a double 2.19 acre lot with an inground pool with plenty of room for outdoor living and gardening! With a spacious living room, a large family-style eat-in kitchen, two-car garage, outdoor deck, bonus "Carolina" room, formal dining room, and more you will be

  Lindsey Moore Wolfe & Taylor, Inc.

  123 Timberlake Dr, Florence, SC 29501
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  /30

  $183,900

  • 3 Beds
  • 2 Baths
  • 1,568 Sq Ft

  1007 Springwood Dr, Florence, SC 29501

  Welcome to 1007 Springwood Drive, a well-maintained home offering comfort and convenience in a peaceful Florence setting. Featuring 3 bedrooms, 2 bathrooms, and approximately 1,568 square feet of living space, this property provides a functional layout designed for everyday living. Recent improvements make this home move-in ready, including brand-new insulated windows for improved energy

  Christopher Frederick exp Realty Greyfeather Group

  1007 Springwood Dr, Florence, SC 29501
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  /7

  $115,000

  • Land
  • 1.33 Acres
  • $86,466 per Acre

  2206 Wellesly Ct, Florence, SC 29505

  Rare Opportunity in Prestigious Queensferry! Welcome to one of the last remaining residential lots in the highly sought-after Queensferry subdivision—Florence’s premier address for luxury living. Spanning 1.33 acres, this spacious homesite offers the perfect setting to build your custom dream home, surrounded by stately residences and mature landscaping. Enjoy the privacy and exclusivity of this

  Reeves Cannon Greystone Properties, LLC

  2206 Wellesly Ct, Florence, SC 29505
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  /3

  $119,000

  • Land
  • 1.97 Acres
  • $60,406 per Acre

  TBD E Mciver Rd, Florence, SC 29506

  Commercial Lot – 1.96 Acres | Excellent Location! Don’t miss this rare opportunity to own nearly 2 acres of commercially zoned land in a high-traffic, rapidly developing area. This 1.96-acre parcel offers endless potential that is located in a desirable and accessible location and it's ready for your vision.

  Joi Perkins Re/max Professionals

  TBD E Mciver Rd, Florence, SC 29506
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  /18

  $355,000

  • Land
  • 53.53 Acres
  • $6,632 per Acre

  53 Acres Old River Rd, Florence, SC 29505

  Come discover the beauty of this expansive 53 acre parcel located in the Claussen Community. This rare opportunity provides the perfect blend of natural beauty and the potential to build your dream home on your private farm. Located just a short drive back into Florence it offers the conveniences of town while living enjoying private farm living. Please call your agent today to schedule your

  Kevin Pryor Greystone Properties, LLC

  53 Acres Old River Rd, Florence, SC 29505
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  /73

  $979,000

  • 4 Beds
  • 4.5 Baths
  • 5,764 Sq Ft

  451 Green Acres Rd, Florence, SC 29505

  Welcome to your own private retreat in Florence County—a true nature lover’s paradise where deer wander through the yard each evening and tranquility surrounds you at every turn. Spanning 24 acres, this extraordinary estate offers just shy of 6,000 square feet of beautifully designed living space, blending classic charm with modern comforts in a peaceful country setting. As you step inside,

  Natalie Taflinger EXP Realty LLC

  451 Green Acres Rd, Florence, SC 29505
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  /2

  $295,000

  • Land
  • 50.1 Acres
  • $5,888 per Acre

  4004 & 3924 Redbird Rd, Florence, SC 29505

  Two exceptional parcels on Redbird Lane—22.94 and 27.16 acres—offering that rare chance to own two 20+ acre tracts in close proximity. Whether you're looking to build your dream home, establish a family compound, or simply stake out your own private slice of the countryside, this is the kind of space that's getting harder to find. If privacy is what you want, this delivers. Expansive acreage

  Nell Folkens Folkens Real Estate, LLC

  4004 & 3924 Redbird Rd, Florence, SC 29505
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  /46

  $325,000

  • 3 Beds
  • 2 Baths
  • 1,910 Sq Ft

  2 Bayswater Rd, Florence, SC 29506

  What a Find! Located in Quinby Forest, this neat older home sits on a generous 1.45 acre corner lot – one of the largest if not the largest lot in the neighborhood. Offering over 1900 square feet, this home features 3 bedrooms, 2 full baths, formal dining room, formal living room with decorative fireplace & cozy den with wood burning fireplace. The kitchen is spacious with a breakfast area that

  Sherri Hardee ERA Leatherman Realty, Inc.

  2 Bayswater Rd, Florence, SC 29506
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  /9

  $700,000

  • Land
  • 3.53 Acres
  • $198,300 per Acre

  1329 Turner Rd, Florence, SC 29506

  Commercial Land Tract Available 1329 Turner Road 3.53 acres with paved road frontage on 3 sides. Estimated 630’ on Freedom Blvd. Highly attractive curve with very high visibility and easy access. Over 17,000 VPD Rapidly growing area.

  Corey Craig Diamond Shores Realty

  1329 Turner Rd, Florence, SC 29506
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  /23

  $217,900

  • 3 Beds
  • 2 Baths
  • 1,949 Sq Ft

  3544 E National Cemetery Rd, Florence, SC 29506

  AS IS!!!!! Bring all offers! Looking for some space? Long driveway! 1.45 acres! New Metal Roof June 2025. Lots of updates! HVAC 2022, New plumbing in bathrooms 2024, Septic Tank pumped 2024, Updated electrical panels 2024, Remodeled hall bath 2024, hardwood floors refinished in 2022, new kitchen cabinets 2024. Grape Vines (muscadine and scuppernong), pear tree, fig tree, and pecan trees.

  Bobbie Housand Home Sales of Florence

  3544 E National Cemetery Rd, Florence, SC 29506
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  /72

  $2,250,000

  • 8 Beds
  • 11 Baths
  • 13,375 Sq Ft

  1308 S Lazar Place, Florence, SC 29501

  Magnificent 13,375 sq ft French Provincial estate on a premium corner lot. This architectural masterpiece showcases the finest in European-inspired design with modern luxury finishes. Situated on an oversized corner lot with circular drive, this distinguished property offers unparalleled elegance and functionality. Estate Features: ~ 8 bedrooms providing exceptional flexibility for family,

  Jean Leatherman ERA Leatherman Realty, Inc.

  1308 S Lazar Place, Florence, SC 29501
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  /4

  $3,500,000

  • Land
  • 59.44 Acres
  • $58,883 per Acre

  880 Freedom Blvd, Florence, SC 29506

  Prime 59-Acre Parcel in Rapidly Growing Area – Unlimited Potential Don’t miss this rare opportunity to own 59 acres of unzoned land in one of the fastest-growing areas in the region. Perfectly positioned for future development, investment, or private use, this expansive property offers unmatched flexibility and endless possibilities. Located just minutes from key transportation routes,

  Emily Fisher exp Realty Greyfeather Group

  880 Freedom Blvd, Florence, SC 29506
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  /5

  $465,000

  • Land
  • 2.33 Acres
  • $199,571 per Acre

  0 S Cashua Dr, Florence, SC 29501

  Prime 2.33-Acre Multi-Use Property in High-Growth Area – Florence, SC Don't miss this rare opportunity to own 2.33 acres of premium real estate in one of Florence’s most rapidly developing and high-traffic areas. This versatile property offers exceptional visibility and accessibility, making it ideal for a wide range of ventures—retail, office space, hospitality, medical, or mixed-use

  Reeves Cannon Greystone Properties, LLC

  0 S Cashua Dr, Florence, SC 29501
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  /33

  $280,000

  • 2 Beds
  • 2 Baths
  • 1,493 Sq Ft

  3719 Pine Haven Dr, Florence, SC 29506

  This beautifully maintained, nearly new 2-bedroom, 2-bathcustom residence offers 1,493 square feet of refined living space on a generous 1.28-acre lot-free from HOA restrictions. Thoughtfully designed with quality and functionality in mind, the home features high-end finishes throughout, including energy-efficient LED lighting, a professional-grade gas range, quartz countertops, bespoke

  Alan Cardona

  3719 Pine Haven Dr, Florence, SC 29506
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  /8

  $1,900,000

  • Land
  • 7.27 Acres
  • $261,348 per Acre

  3312 State Road S-21-545, Florence, SC 29501

  Incredible opportunity for commercial developers! This two parcel package is 7.27 acres total and is ideally located just off I-95 and directly across from the newly built Quick Trip store. With high traffic counts, outstanding visibility, and easy access, this level, buildable property is perfect for a wide range of commercial uses including retail, service stations, hospitality, and more. These

  Sarah Blaire Goodson Brown & Coker Realty

  3312 State Road S-21-545, Florence, SC 29501
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  /42

  $215,000

  • 4 Beds
  • 1.5 Baths
  • 1,584 Sq Ft

  201 N Williamson Rd, Florence, SC 29506

  This home is being sold AS-IS! This charming brick ranch home sits on 1.8 acres and offers a cozy yet spacious layout. Built in 1956, the home features three bedrooms, 1.5 baths, and a **bonus room**. Inside, you'll find hardwood floors throughout, with tile in the bathrooms. The home includes a den, kitchen, living room, and dining room, plus two fireplaces. The attached laundry room and

  Gary Martin exp Realty Greyfeather Group

  201 N Williamson Rd, Florence, SC 29506
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  /14

  $4,550,000

  • Land
  • 12.65 Acres
  • $359,684 per Acre

  tbd E Palmetto, Florence, SC 29506

  High-Visibility Commercial Parcel – E. Palmetto Street & Dunton Drive, Florence, SC This exceptional ±12.65-acre commercial parcel offers 493 feet of frontage on E. Palmetto Street and 1,063 feet on Dunton Drive, positioned just off the corner of Hwy 327 and E. Palmetto Street. Located approximately 5 miles from I-95 Exit 170 (327)—the same exit as Buc-ee’s—this site enjoys consistently high

  Dorothy Corriero ERA Leatherman Realty, Inc.

  tbd E Palmetto, Florence, SC 29506
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  /7

  $630,000

  • Land
  • 3.5 Acres
  • $180,000 per Acre

  TBD Quartz Ln, Florence, SC 29506

  Prime Commercial Opportunity in Sandstone Development – Florence, SC Strategically positioned within the thriving Sandstone Commercial development, this parcel offers exceptional visibility and high traffic exposure from all four directions. Located directly behind Booty Brothers on E Palmetto Street, the site benefits from seamless access via Quartz Lane and Freedom Blvd through Dunton Drive.

  Dorothy Corriero ERA Leatherman Realty, Inc.

  TBD Quartz Ln, Florence, SC 29506
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  /14

  $1,870,000

  • Land
  • 5 Acres
  • $374,000 per Acre

  TBD E Palmetto Street & Quartz Ln, Florence, SC 29506

  Approximately 536 feet of road frontage on E Palmetto Road (state road) offers quick access east and west via E Palmetto Street. It's directly across from Booty Brothers and experiences high traffic from automobiles, commercial vehicles, and motorhomes. Located close to I-95 and exit 170 (327), it's near the AESC plant and training center, Amazon, Pee Dee Commerce Center East and West, FMU, both

  Dorothy Corriero ERA Leatherman Realty, Inc.

  TBD E Palmetto Street & Quartz Ln, Florence, SC 29506
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  /4

  $84,900

  • Land
  • 1.91 Acres
  • $44,450 per Acre

  928 Ashton Dr, Florence, SC 29501

  Mature 1.91+/- acre Cul-de-sac lot located in the desired Vintage Place!!

  Hank Edwards Aiken & Company

  928 Ashton Dr, Florence, SC 29501
• 

  

  /24

  $870,000

  • Land
  • 4.65 Acres
  • $187,097 per Acre

  1050 Freedom Blvd, Florence, SC 29506

  Prime Commercial Opportunity – Approx. 4.65 Acres on Freedom Blvd, Florence, SC. Located at the high-visibility corner of Freedom Blvd and Gilbert Drive, this tract offers unmatched potential in a rapidly expanding area of Florence. With 706 feet of frontage on Freedom Blvd with Commercial General zoning, the site is ideal for a wide range of development projects. Property Highlights:

  Dorothy Corriero ERA Leatherman Realty, Inc.

  1050 Freedom Blvd, Florence, SC 29506
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  /6

  $50,000

  • Land
  • 3.9 Acres
  • $12,821 per Acre

  TBD Bazen Ln, Florence, SC 29505

  SECLUDED, WOODED, 3.90 ACRES 3.90 acres at the end of Bazen Lane off Hwy. 51. This is a nice, wooded piece of property that would be a great home site. It is located about 5 minutes outside of Florence. Land is located on the back right where Bazen Lane ends. Owner has a survey on the 3.90 Acres.

  Charles Munn Drayton Realty Group

  TBD Bazen Ln, Florence, SC 29505

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