113

Sikeston, MO Homes for Sale

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  • /38

    $315,000

    • 3 Beds
    • 2 Baths
    • 2,495 Sq Ft

    202 N Brushwick Ave, Sikeston, MO 63801

    Welcome home to this stunning single-level retreat on a huge lot, offering the perfect blend of space, comfort, and style. Step inside to a large open-concept floor plan filled with natural light from dramatic floor-to-ceiling windows, creating an airy, inviting atmosphere ideal for both everyday living and entertaining.The warm and inviting den features beautiful wood paneling, adding

    Lawren McMullan EDGE Realty, ERA Powered

    202 N Brushwick Ave, Sikeston, MO 63801
  • /9

    $127,000

    • 3 Beds
    • 1.5 Baths
    • 1,466 Sq Ft

    114 W North St, Sikeston, MO 63801

    Full of character and opportunity, this spacious 3-bedroom, 1.5-bath historic Colonial offers the perfect canvas to create your dream home. Tall ceilings, a grand front porch, and vintage charm throughout set the stage for something truly special. The layout offers generous living space, and the cellar provides extra storage or storm shelter functionality. Whether you're an investor looking for

    Jenny Elliott Mossy Oak Properties Mozark Re

    114 W North St, Sikeston, MO 63801
  • /32

    $149,900

    • 3 Beds
    • 2 Baths
    • 1,250 Sq Ft

    219 Petroleum St, Sikeston, MO 63801

    Take a look at this nice, clean, move-in ready home sporting a NEW ROOF! The charming front porch leads to an open living, kitchen & dining area. Primary bedroom with 3/4 bath, two additional bedrooms, one full bath and a one car attached carport, a 12x24 storage shed with walk-in door and garage door. This is the perfect size for a starter home or someone ready to downsize. Come and see for

    Rebecca Shaver C. Lawrence Realty LLC

    219 Petroleum St, Sikeston, MO 63801
  • /34

    $215,000

    • 4 Beds
    • 2 Baths
    • 1,922 Sq Ft

    406 Lynn St, Sikeston, MO 63801

    Located in the highly sought-after Mini Farms subdivision just outside Sikeston, this beautifully remodeled 4-bedroom, 2-bath home on 1.84 acres offers the perfect combination of modern updates and country-style living with convenient access to town. The home was completely remodeled in 2025 and includes major system updates such as new gas heat and air, a new gas tankless water heater, and an

    Lynsey Perry Silverthorn Realty, LLC

    406 Lynn St, Sikeston, MO 63801
  • /12

    $139,000

    • 3 Beds
    • 1 Bath
    • 1,080 Sq Ft

    2012 Kentucky St, Sikeston, MO 63801

    Charming 3 bedroom, 1 bathroom home featuring warm and inviting living spaces. Recent updates include an updated bathroom, freshly painted kitchen cabinets, and exterior paint improvements that add to the home’s curb appeal. This property offers comfortable living and great potential, making it a perfect option for first-time home buyers, those looking to downsize, or investors seeking an

    Rebecca Ault EDGE Realty, ERA Powered

    2012 Kentucky St, Sikeston, MO 63801
  • /36

    $260,000

    • 3 Beds
    • 3 Baths
    • 1,492 Sq Ft

    119 Depro Ave, Sikeston, MO 63801

    Newly remodeled and move-in ready just outside Sikeston! Sitting on a spacious corner lot with 0.7187 acres, this home gives you room to breathe and room to work. You’ll love the outdoor setup with a large shed plus a brand-new 30x40 pole barn, perfect for hobbies, storage, or a workshop. New roof, fresh updates, and space inside and out—this one checks all the boxes!

    Jessica Moore EXP Realty, LLC

    119 Depro Ave, Sikeston, MO 63801
  • /19

    $189,000

    • 4 Beds
    • 2 Baths
    • 1,914 Sq Ft

    410 Hux St, Sikeston, MO 63801

    Discover your dream home in this delightful 4-bedroom, 2-bath ranch that perfectly blends comfort and style. Nestled on a serene street, this inviting residence features a spacious front porch, ideal for sipping morning coffee or enjoying evening sunsets. Step inside to find a bright and airy layout that welcomes you with warmth and charm.The heart of the home boasts an open living area,

    Brandon Kielhofner EPM Real Estate

    410 Hux St, Sikeston, MO 63801
  • /16

    $205,000

    • 3 Beds
    • 2 Baths
    • 1,200 Sq Ft

    2163 E County Highway 450, Sikeston, MO 63801

    Welcome to this beautifully maintained one-owner home, thoughtfully designed and built with comfort in mind. Offering 3 bedrooms, 2 bathrooms, and approximately 1,200 sq ft of living space, this property blends an open, inviting layout with the peaceful feel of country living. Step inside to an open concept living room and kitchen, perfect for entertaining, family gatherings, or simply enjoying

    Christy Lawrence C. Lawrence Realty LLC

    2163 E County Highway 450, Sikeston, MO 63801
  • /14

    $119,000

    • 3 Beds
    • 1 Bath
    • 1,080 Sq Ft

    318 Kendall St, Sikeston, MO 63801

    Welcome home to this fully remodeled 3-bedroom, 1-bath charmer, offering modern comfort and timeless style. Every detail has been thoughtfully updated, including fresh flooring, contemporary fixtures, new paint, and an inviting open layout that maximizes both light and space. All three bedrooms are generously sized, providing flexibility for family, guests, or a home office. The updated bathroom

    Lawren McMullan EDGE Realty, ERA Powered

    318 Kendall St, Sikeston, MO 63801
  • /11

    $127,500

    • 2 Beds
    • 1 Bath
    • 910 Sq Ft

    628 Moore Ave, Sikeston, MO 63801

    This charming bungalow in Sikeston's historic district has been beautifully updated and is ready for its new owner. Featuring 2 bedrooms and 1 bath, it's the perfect home for first-time buyers or anyone looking to downsize. Conveniently located withing walking distance to the YMCA and local grocery stores, this home offers both everyday convenience and timeless charm.

    Rene Church Century 21 Premiere Realty

    628 Moore Ave, Sikeston, MO 63801
  • /9

    $106,000

    • Land
    • 0.86 Acre
    • $123,256 per Acre

    190 Cypress Branch Rd, Sikeston, MO 63801

    Greenfield North will be a gated, fenced cul-de-sac community located inside the city limits of Sikeston, just off Highway 61. You'll experience the convenience of town combined with the calm of a quiet neighborhood. Enjoy a private secure location for your custom home. The covenants and restrictions were designed to help preserve property values and maintain a safe, high-quality, and comfortable

    Tim Merideth Century 21 Premiere Realty

    190 Cypress Branch Rd, Sikeston, MO 63801
  • /2

    $15,000

    • Land
    • 0.2 Acre
    • $75,000 per Acre

    807 Bollweevil Blvd, Sikeston, MO 63801

    This vacant residential lot is ready for you to build on, and priced to help you get started quickly. Covenants and restrictions are in place to help protect your investment. Located inside Sikeston City Limits. Additional Rooms: In Platted Subdv.

    Tim Merideth Century 21 Premiere Realty

    807 Bollweevil Blvd, Sikeston, MO 63801
  • /3

    $42,500

    • Land
    • 0.3 Acre
    • $141,667 per Acre

    404 Aster, Sikeston, MO 63801

    Welcome to Saddleridge South, 2nd Addition! Located inside the city limits of Sikeston, these lots have utilities already ran to them and are ready for construction to begin. You can be the general contractor, or we can introduce you to some of the area's finest builders to work with. Covenants and restrictions were crafted to help protect property value and are available upon request. These are

    Tim Merideth Century 21 Premiere Realty

    404 Aster, Sikeston, MO 63801
  • /2

    $79,900

    • 3 Beds
    • 2 Baths
    • 1,232 Sq Ft

    338 E Gladys St, Sikeston, MO 63801

    Great opportunity for investors! This 3-bedroom property offers solid potential as a rental or flip, with a manageable layout and room to add value. Whether you're expanding your portfolio or getting started in real estate, this is a smart, affordable option.

    Christina Essner EXP Realty, LLC

    338 E Gladys St, Sikeston, MO 63801
  • /2

    $54,900

    • 2 Beds
    • 1 Bath
    • 600 Sq Ft

    627 Vernon Ave, Sikeston, MO 63801

    Great opportunity for investors! This 2-bedroom property offers solid potential as a rental or flip, with a manageable layout and room to add value. Whether you're expanding your portfolio or getting started in real estate, this is a smart, affordable option.

    Christina Essner EXP Realty, LLC

    627 Vernon Ave, Sikeston, MO 63801
  • /17

    $37,900

    • 2 Beds
    • 1 Bath
    • 728 Sq Ft

    309 Benton St, Sikeston, MO 63801

    Charming 2-bedroom, 1-bath home with great potential. A warm and welcoming layout offers the perfect canvas for your personal touches. Make it your own and enjoy the possibilities!

    Mike Zouglas REO Xpress, LLC

    309 Benton St, Sikeston, MO 63801
  • /3

    $42,500

    • Land
    • 0.28 Acre
    • $151,786 per Acre

    416 Secretariat, Sikeston, MO 63801

    Welcome to Saddleridge South, 2nd Addition! Located inside the city limits of Sikeston, these lots have utilities already ran to them and are ready for construction to begin. You can be the general contractor, or we can introduce you to some of the area's finest builders to work with. Covenants and restrictions were crafted to help protect property value and are available upon request. These are

    Tim Merideth Century 21 Premiere Realty

    416 Secretariat, Sikeston, MO 63801
  • /8

    $90,000

    • Land
    • 3 Acres
    • $30,000 per Acre

    2215 State Highway U, Sikeston, MO 63801

    Imagine a quiet country setting just a short drive to Interstate 55 with only 15 minutes to both Cape Girardeau & Sikeston. This property is not only located in Kelly School district but situated directly on a paved state road with access to county water. This cleared lot is ready for you to build your dream home on with a lot of space to stretch out and enjoy a peaceful country setting.

    Kyla Evans Paul Kitchen & Associates

    2215 State Highway U, Sikeston, MO 63801
  • /3

    $42,500

    • Land
    • 0.27 Acre
    • $157,407 per Acre

    405 Aster, Sikeston, MO 63801

    Welcome to Saddleridge South, 2nd Addition! Located inside the city limits of Sikeston, these lots have utilities already ran to them and are ready for construction to begin. You can be the general contractor, or we can introduce you to some of the area's finest builders to work with. Covenants and restrictions were crafted to help protect property value and are available upon request. These are

    Tim Merideth Century 21 Premiere Realty

    405 Aster, Sikeston, MO 63801
  • /21

    $1,000,000

    • 1,800 Sq Ft

    361 County Highway 405, Sikeston, MO 63801

    Exceptional Poultry Farm Opportunity with a 1,800 sqft 3 bed 2 bath home that was built in 2020. Presenting a rare opportunity to acquire a modern, income-producing poultry operation. This farm has been meticulously maintained and is available due to the owners’ retirement. Designed with efficiency and productivity in mind, the property offers state-of-the-art facilities and equipment to support

    Christy Lawrence C. Lawrence Realty LLC

    361 County Highway 405, Sikeston, MO 63801
  • /3

    $42,500

    • Land
    • 0.39 Acre
    • $108,974 per Acre

    407 Aster, Sikeston, MO 63801

    Welcome to Saddleridge South, 2nd Addition! Located inside the city limits of Sikeston, these lots have utilities already ran to them and are ready for construction to begin. You can be the general contractor, or we can introduce you to some of the area's finest builders to work with. Covenants and restrictions were crafted to help protect property value and are available upon request. These are

    Tim Merideth Century 21 Premiere Realty

    407 Aster, Sikeston, MO 63801
  • /3

    $42,500

    • Land
    • 0.39 Acre
    • $108,974 per Acre

    308 Citation Dr, Sikeston, MO 63801

    Come see Sikeston's newest subdivision! These are excellent sites for first-time home buyers, families, or those wanting to downsize. Turn south off Broadway onto South Illinois Avenue to two new cul-de-sacs, ensuring reduced traffic. This subdivision is inside Sikeston City limits, and has covenants and restrictions to help protect your investment. Super easy, fast access to Highway 60 and

    Tim Merideth Century 21 Premiere Realty

    308 Citation Dr, Sikeston, MO 63801
  • /2

    $15,000

    • Land
    • 0.28 Acre
    • $53,571 per Acre

    801 Bollweevil Blvd, Sikeston, MO 63801

    This vacant residential lot is ready for you to build on, and priced to help you get started quickly. Covenants and restrictions are in place to help protect your investment. Located inside Sikeston City Limits. Additional Rooms: In Platted Subdv.

    Tim Merideth Century 21 Premiere Realty

    801 Bollweevil Blvd, Sikeston, MO 63801
  • /3

    $42,500

    • Land
    • 0.4 Acre
    • $106,250 per Acre

    402 Secretariat, Sikeston, MO 63801

    Welcome to Saddleridge South, 2nd Addition! Located inside the city limits of Sikeston, these lots have utilities already ran to them and are ready for construction to begin. You can be the general contractor, or we can introduce you to some of the area's finest builders to work with. Covenants and restrictions were crafted to help protect property value and are available upon request. These are

    Tim Merideth Century 21 Premiere Realty

    402 Secretariat, Sikeston, MO 63801
  • /2

    $15,000

    • Land
    • 0.21 Acre
    • $71,429 per Acre

    811 Cotton Ridge Dr, Sikeston, MO 63801

    This vacant residential lot is ready for you to build on, and priced to help you get started quickly. Covenants and restrictions are in place to help protect your investment. Located inside Sikeston City Limits. Additional Rooms: In Platted Subdv.

    Tim Merideth Century 21 Premiere Realty

    811 Cotton Ridge Dr, Sikeston, MO 63801
  • /4

    $200,000

    • Land
    • 18.5 Acres
    • $10,811 per Acre

    2093 E County Highway 450, Sikeston, MO 63801

    Discover the perfect blend of open space and natural beauty with this 18.5-acre tract offering a variety of potential uses. Featuring a mix of wooded areas and open ground, this property is ideal for building your dream home, creating a private retreat, or investing for the future. Abundant wildlife—including deer and turkey—makes this a great spot for nature lovers or recreational use. Multiple

    Tara Newell-Koehler Century 21 Ashland Realty

    2093 E County Highway 450, Sikeston, MO 63801
  • /2

    $15,000

    • Land
    • 0.2 Acre
    • $75,000 per Acre

    811 Bollweevil Blvd, Sikeston, MO 63801

    This vacant residential lot is ready for you to build on, and priced to help you get started quickly. Covenants and restrictions are in place to help protect your investment. Located inside Sikeston City Limits. Additional Rooms: In Platted Subdv.

    Tim Merideth Century 21 Premiere Realty

    811 Bollweevil Blvd, Sikeston, MO 63801
  • /9

    $108,000

    • Land
    • 0.79 Acre
    • $136,709 per Acre

    170 Cypress Branch Rd, Sikeston, MO 63801

    Greenfield North will be a gated, fenced cul-de-sac community located inside the city limits of Sikeston, just off Highway 61. You'll experience the convenience of town combined with the calm of a quiet neighborhood. Enjoy a private secure location for your custom home. The covenants and restrictions were designed to help preserve property values and maintain a safe, high-quality, and comfortable

    Tim Merideth Century 21 Premiere Realty

    170 Cypress Branch Rd, Sikeston, MO 63801
  • /2

    $54,900

    • 2 Beds
    • 1 Bath
    • 736 Sq Ft

    319 Benton St, Sikeston, MO 63801

    Great opportunity for investors! This 2-bedroom property offers solid potential as a rental or flip, with a manageable layout and room to add value. Whether you're expanding your portfolio or getting started in real estate, this is a smart, affordable option.

    Christina Essner EXP Realty, LLC

    319 Benton St, Sikeston, MO 63801
  • /3

    $42,500

    • Land
    • 0.39 Acre
    • $108,974 per Acre

    418 Secretariat, Sikeston, MO 63801

    Welcome to Saddleridge South, 2nd Addition! Located inside the city limits of Sikeston, these lots have utilities already ran to them and are ready for construction to begin. You can be the general contractor, or we can introduce you to some of the area's finest builders to work with. Covenants and restrictions were crafted to help protect property value and are available upon request. These are

    Tim Merideth Century 21 Premiere Realty

    418 Secretariat, Sikeston, MO 63801
  • /2

    $69,900

    • 2 Beds
    • 1 Bath
    • 837 Sq Ft

    322 Helen St, Sikeston, MO 63801

    Great opportunity for investors! This 2-bedroom property offers solid potential as a rental or flip, with a manageable layout and room to add value. Whether you're expanding your portfolio or getting started in real estate, this is a smart, affordable option.

    Christina Essner EXP Realty, LLC

    322 Helen St, Sikeston, MO 63801
  • /2

    $15,000

    • Land
    • 0.28 Acre
    • $53,571 per Acre

    800 Cotton Ridge Dr, Sikeston, MO 63801

    This vacant residential lot is ready for you to build on, and priced to help you get started quickly. Covenants and restrictions are in place to help protect your investment. Located inside Sikeston City Limits. Additional Rooms: In Platted Subdv.

    Tim Merideth Century 21 Premiere Realty

    800 Cotton Ridge Dr, Sikeston, MO 63801
  • /2

    $44,000

    • 3 Beds
    • 2 Baths
    • 1,124 Sq Ft

    108 Adams St, Sikeston, MO 63801

    If you are looking for an investment property or a home that requires some TLC, this home is ready for your renovations. Priced to sell quickly, schedule your viewing today!

    Thomas Williams Century 21 Premiere Realty

    108 Adams St, Sikeston, MO 63801
  • /4

    $39,000

    • Land
    • 1.67 Acres
    • $23,353 per Acre

    38 Matt St, Sikeston, MO 63801

    Lauren DeWitt EDGE Realty, ERA Powered

    38 Matt St, Sikeston, MO 63801
  • /4

    $500,000

    1201 Lawrence St, Sikeston, MO 63801

    1.24 acres of commercial land located on the corner of Stallcup Drive and Lawrence Street. This lot is located beside a 60 unit apartment complex; and there is a Lowe's, JC Penney and Taco Bell within walking distance. Concrete streets. Located in New Madrid County, Sikeston city limits. Zoned light industrial.

    Tim Merideth Century 21 Premiere Realty

    1201 Lawrence St, Sikeston, MO 63801
  • /3

    $42,500

    • Land
    • 0.41 Acre
    • $103,659 per Acre

    304 Seabiscuit Dr, Sikeston, MO 63801

    Come see Sikeston's newest subdivision! These are excellent sites for first-time home buyers, families, or those wanting to downsize. Turn south off Broadway onto South Illinois Avenue to two new cul-de-sacs, ensuring reduced traffic. This subdivision is inside Sikeston City limits, and has covenants and restrictions to help protect your investment. Super easy, fast access to Highway 60 and

    Tim Merideth Century 21 Premiere Realty

    304 Seabiscuit Dr, Sikeston, MO 63801
  • /9

    $108,000

    • Land
    • 0.81 Acre
    • $133,333 per Acre

    140 Cypress Branch Rd, Sikeston, MO 63801

    Greenfield North will be a gated, fenced cul-de-sac community located inside the city limits of Sikeston. Just off Highway 61. You'll experience the convenience of town combined with the calm of a quiet neighborhood. Enjoy a private, secure location for your custom home. The covenants and restrictions were designed to help preserve property values and maintain a safe, high-quality, and

    Tim Merideth Century 21 Premiere Realty

    140 Cypress Branch Rd, Sikeston, MO 63801
  • /11

    $99,900

    • 3 Beds
    • 1 Bath
    • 1,237 Sq Ft

    303 Greer Ave, Sikeston, MO 63801

    Are you ready for a small home in Sikeston? You can sit on the covered, front porch and enjoy a morning cup of coffee while watching others out and about! This Bungalow-style home boasts of 3 bedrooms, 1 bathroom, an eat-in kitchen, a covered carport in back yard all located on a corner lot. The kitchen has several cabinets, an island along the wall, and a range and a dishwasher included. It's

    Scott Harrison Delta Realty, LLC

    303 Greer Ave, Sikeston, MO 63801
  • /12

    $195,000

    • 3 Beds
    • 2 Baths
    • 1,421 Sq Ft

    112 N 6th St, Sikeston, MO 63801

    Step inside to find a bright and airy living space featuring a freshly painted interior and brand-new flooring throughout. The heart of the home is the spacious, open-concept kitchen—perfect for entertaining—boasting ample cabinetry and a layout that flows seamlessly into the dining and living areas. Both bathrooms have been updated, ensuring this home is move-in ready from day one.Situated

    Kaci Self Epique Realty

    112 N 6th St, Sikeston, MO 63801
  • /4

    $500,000

    1209 Lawrence St, Sikeston, MO 63801

    Commercial land on a corner lot available for development in Sikeston's busiest retail area. 1.05 acres zoned light industrial is located directly across the street from Wal-Mart. Other major retailers located close by include JC Penney, Goodies, and Lowe's. Located in New Madrid county, Sikeston city limits.

    Tim Merideth Century 21 Premiere Realty

    1209 Lawrence St, Sikeston, MO 63801

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Why Live in Sikeston

Sikeston, Missouri, is a small city situated midway between St. Louis and Memphis, nestled in the "Missouri Bootheel." With a population of 16,000, Sikeston offers tradition and opportunity, highlighted by its thriving job market and strong schools. The city's historic charm is evident in its late 19th and early 20th-century homes, including Victorian and Colonial Revival styles, particularly in the downtown area. Housing styles throughout Sikeston are diverse, ranging from historic homes to midcentury architecture, including ranch and traditional two-story homes. Major employers in the area include Unilever, SoutheastHEALTH, Sikeston Public Schools, and Missouri Delta Medical Center. Sikeston Public Schools, known as Sikeston R-VI School District, offers both traditional and virtual academy options, along with several faith-based private schools.

Sikeston boasts numerous attractions, including the Sikeston Recreational Complex, which features a skate park, sports courts, fields, and a fishing lake. The city maintains 16 parks and eight trails, with the Cottonbelt Trail being a notable 1.5-mile paved multi-use trail. Indoor recreational facilities include the Clinton Building, YMCA, and Fox Haven Country Club. The Factory Outlet Mall and Walmart provide shopping options, while dining staples like Kirby’s Sandwich Shop and Lambert’s Café offer unique local flavors. Sikeston hosts several annual events, such as the Hot Air Balloon Festival, Cotton Carnival, and the Jaycee Bootheel Rodeo.

Sikeston is conveniently located within 5 miles of Interstates 55 and 57, with Cape Girardeau Regional Airport 30 miles away. Despite severe weather challenges, Sikeston remains a vibrant community with a low crime risk compared to the national average.

Frequently Asked Questions

What is the average home price in Sikeston, MO?
Homes for sale in Sikeston, MO have an average home price of $185,306.
How many homes have sold over the last 12 months in Sikeston, MO?
181 homes have sold in Sikeston, MO over the last 12 months.
What are the most popular zip codes in Sikeston, MO?
The most popular zip codes in Sikeston, MO include 63801, 63823, 63845, 63771 and 63834.
How much do you need to make to afford a house in Sikeston?
The median home price in Sikeston is $174,900. If you put a 20% down payment of $35,000 and had a 30-year fixed mortgage with an interest rate of 6.22%, your estimated principal and interest payment would be $860 a month plus property taxes, HOA fees, home insurance, PMI, and utilities. Using the 28% rule, you would need to make at least $37K a year to afford the median home price in Sikeston. Learn how much home you can afford with our Home Affordability Calculator.
How are the schools in Sikeston, MO?
Sikeston, MO has highly rated public and private schools. Some of the best schools in Sikeston based on Niche Grades are The Christian Academy, Sikeston Kindergarten Center and Sikeston Senior High School. Browse all the schools in Sikeston, MO to learn more.

Home Trends in Sikeston, MO

Housing Trends

Median Sale Price
$177,000
Median Single Family Sale Price
$125,000
Median Townhouse Sale Price
$400,000
Median 2 Bedroom Sale Price
$175,000
Median 1 Bedroom Sale Price
$144,950
Average Price Per Sq Ft
$96
Number of Homes for Sale
50
Last 12 months Home Sales
181
Months of Supply
3.30
Median List Price
$174,900
Median Change From 1st List Price
4%
Median Home Sale Price YoY Change
7%
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