Sikeston, MO Homes for Sale

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  /4

  $500,000

  1209 Lawrence St, Sikeston, MO 63801

  Commercial land on a corner lot available for development in Sikeston's busiest retail area. 1.05 acres zoned light industrial is located directly across the street from Wal-Mart. Other major retailers located close by include JC Penney, Goodies, and Lowe's. Located in New Madrid county, Sikeston city limits.

  Tim Merideth Century 21 Premiere Realty

  1209 Lawrence St, Sikeston, MO 63801
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  /2

  $48,000

  • 2 Beds
  • 1 Bath
  • 1,335 Sq Ft

  420 Malcolm Ave, Sikeston, MO 63801

  If you are looking for an investment property or a home that requires some TLC, this home is ready for your renovations. Priced to sell quickly, schedule your viewing today!

  Thomas Williams Century 21 Premiere Realty

  420 Malcolm Ave, Sikeston, MO 63801
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  /38

  $355,000

  • 3 Beds
  • 3 Baths
  • 6,536 Sq Ft

  901 Moore Ave, Sikeston, MO 63801

  Do you like both indoor and outdoor space? This is the one for you. This home includes a large sunroom with ceiling fans located on the back of the house overlooking gorgeous landscaping. There's also outdoor space on the composite deck if you'd like a little sun. This nice brick home is on a corner lot in Sikeston's north end. Inside, the kitchen was recently remodeled with a nice island and

  Tim Merideth Century 21 Premiere Realty

  901 Moore Ave, Sikeston, MO 63801
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  /3

  $42,500

  • Land
  • 0.34 Acre
  • $125,000 per Acre

  404 Secretariat, Sikeston, MO 63801

  Welcome to Saddleridge South, 2nd Addition! Located inside the city limits of Sikeston, these lots have utilities already ran to them and are ready for construction to begin. You can be the general contractor, or we can introduce you to some of the area's finest builders to work with. Covenants and restrictions were crafted to help protect property value and are available upon request. These

  Tim Merideth Century 21 Premiere Realty

  404 Secretariat, Sikeston, MO 63801
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  /66

  $319,000

  • 2 Beds
  • 2 Baths
  • 1,858 Sq Ft

  814 Auburn Dr Unit 7, Sikeston, MO 63801

  Stunning is exactly the word that come to mind when you see this property! Step into the beautiful condominiums at Arbor Walk with this new listing! Unit #7, Sunstone is a gorgeous 2 bed 2 bath condo just under 1900 sq ft. It truly lives up to its name, Sunstone, with all of the natural light coming in from the balcony and large windows! Open Concept with beautiful hardwood flooring

  Leann Adams Silverthorn Realty, LLC

  814 Auburn Dr Unit 7, Sikeston, MO 63801
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  /20

  $285,000

  • 5 Beds
  • 3 Baths
  • 3,211 Sq Ft

  912 Plantation Blvd, Sikeston, MO 63801

  Are you looking for a home that is turn-key and well-maintained both inside and outside? Well, search no more! Check out this charming, welcoming home in a well-established neighborhood. This home is nestled on the end of a quiet street and will not be on the market long! This home offers an inviting foyer, laminate and ceramic tile flooring all throughout. The open-concept living room is great

  Katrina Dowell C. Lawrence Realty LLC

  912 Plantation Blvd, Sikeston, MO 63801
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  /4

  $195,000

  • Land
  • 0.72 Acre
  • $270,833 per Acre

  116 Hospitality Dr, Sikeston, MO 63801

  Vacant, level lot. Not in the flood plain.

  Larry Lindsey Century 21 Premiere Realty

  116 Hospitality Dr, Sikeston, MO 63801
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  /2

  $15,000

  • Land
  • 0.24 Acre
  • $62,500 per Acre

  810 Cotton Ridge Dr, Sikeston, MO 63801

  This vacant residential lot is ready for you to build on, and priced to help you get started quickly. Covenants and restrictions are in place to help protect your investment. Located inside Sikeston City Limits. Additional Rooms: In Platted Subdv.

  Tim Merideth Century 21 Premiere Realty

  810 Cotton Ridge Dr, Sikeston, MO 63801
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  /10

  $80,000

  • 2 Beds
  • 1 Bath
  • 884 Sq Ft

  516 Coleman St, Sikeston, MO 63801

  Welcome to 516 Coleman St. in Sikeston, a 2-bedroom home that combines classic charm with modern updates. Step inside to find some original hardwood floors that add warmth and character, complemented by new carpet in the bedrooms for a cozy touch. The fully remodeled bathroom features stylish finishes and a fresh, contemporary feel. This home offers comfortable living spaces, great natural light,

  Lauren DeWitt EDGE Realty, ERA Powered

  516 Coleman St, Sikeston, MO 63801
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  /12

  $58,049

  • 3 Beds
  • 1 Bath
  • 1,029 Sq Ft

  209 Russell Ave, Sikeston, MO 63801

  This 3-bedroom, 1-bath home offers 1,029 square feet of living space and great potential for anyone looking to update a property to their own taste. Inside, you’ll find a layout that includes both a living room and a family room, giving you extra space for relaxing, entertaining, or creating a home office. The kitchen features generous cabinet storage and a functional layout ready for a refresh.

  Scott Harrison Delta Realty, LLC

  209 Russell Ave, Sikeston, MO 63801
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  /28

  $250,000

  • 3 Beds
  • 2 Baths
  • 1,432 Sq Ft

  911 Pine St, Sikeston, MO 63801

  Amber Prasanphanich EDGE Realty ERA Powered

  911 Pine St, Sikeston, MO 63801
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  /2

  $400,000

  109 Stallcup Dr, Sikeston, MO 63801

  Over 2.5 acres of commercial property located in the heart of Sikeston's booming retail and hospitality area. Just a block from Wal-Mart Supercenter, 2 new hotels, shopping and restaurants, and a half mile to the intersection of US Highways 60 & 61. This is a premium location at an outstanding price.

  Tim Merideth Century 21 Premiere Realty

  109 Stallcup Dr, Sikeston, MO 63801
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  /99

  $690,000

  • 4 Beds
  • 5.5 Baths
  • 5,392 Sq Ft

  1011 N Ranney St, Sikeston, MO 63801

  Nestled in the Historic Downtown District, one of Sikeston's most desirable neighborhoods, you will find a stunning 5392 Sq Ft home on an acre of property! This home has been completely restored while maintaining its original character. You will walk through the imported 1850s mahogany carved wood front door, and to your left, you will find a beautiful study with a built-in bookcase and a

  Tara Roach EDGE Realty, ERA Powered

  1011 N Ranney St, Sikeston, MO 63801
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  /28

  $239,900

  • 3 Beds
  • 2.5 Baths
  • 1,798 Sq Ft

  123 Holmes Dr, Sikeston, MO 63801

  This ALL BRICK home has many upgrades and is MOVE-IN-READY. The home has 3 bedrooms & 2 1/2 baths, one of the full bathrooms is a "Jack & Jill" style. The Heating & Cooling units were NEW in July 2025. ALL the Kitchen appliances stay with the home and were NEW in 2023. Backyard is completely fenced-in. Ask to see the seller's disclosure for all the upgrades and improvements. Average utility bill

  Mike Leible Century 21 Premiere Realty

  123 Holmes Dr, Sikeston, MO 63801
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  /14

  $99,400

  • 2 Beds
  • 1 Bath
  • 1,000 Sq Ft

  406 W Gladys St, Sikeston, MO 63801

  Step inside this beautifully remodeled 2-bedroom, 1-bath home that’s move-in ready and full of modern updates! Fresh interior and exterior paint give the home a crisp, inviting look, while the brand-new flooring throughout adds warmth and style.Outside, the freshly painted exterior provides excellent curb appeal, and the manageable yard makes maintenance a breeze.Whether you’re a

  Lawren McMullan EDGE Realty, ERA Powered

  406 W Gladys St, Sikeston, MO 63801
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  /2

  $90,000

  • 3 Beds
  • 1 Bath
  • 1,077 Sq Ft

  849 William St, Sikeston, MO 63801

  Enjoy entertaining in this 3-bedroom, 1-bath home with a spacious yard and separate dining room. Updates like the new dryer plug-in, baseboard heaters, fresh interior paint, kitchen cabinets, and sink add modern convenience while keeping maintenance low. Plus, the covered carport provides protected parking. Set up a showing today!

  Tasha Cardin EXP Realty, LLC

  849 William St, Sikeston, MO 63801
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  /3

  $42,500

  • Land
  • 0.39 Acre
  • $108,974 per Acre

  419 Secretariat, Sikeston, MO 63801

  Welcome to Saddleridge South, 2nd Addition! Located inside the city limits of Sikeston, these lots have utilities already ran to them and are ready for construction to begin. You can be the general contractor, or we can introduce you to some of the area's finest builders to work with. Covenants and restrictions were crafted to help protect property value and are available upon request. These

  Tim Merideth Century 21 Premiere Realty

  419 Secretariat, Sikeston, MO 63801
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  /2

  $47,000

  • 4 Beds
  • 2 Baths
  • 1,300 Sq Ft

  408 Carroll St, Sikeston, MO 63801

  If you are looking for an investment property or a home that requires some TLC, this home is ready for your renovations. Priced to sell quickly, schedule your viewing today!

  Thomas Williams Century 21 Premiere Realty

  408 Carroll St, Sikeston, MO 63801
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  /14

  $3,960,000

  0 Ables Rd, Sikeston, MO 63801

  Located on the northwest corner of I-55 and I-57 inside Sikeston City limits, this ground is in a prime location for commercial development. This property can be accessed via Ables Road or County Line Road. Owner will subdivide into smaller tracts. There is power, water and sewer available, all provided by Sikeston Board of Municipal Utilities.

  Tim Merideth Century 21 Premiere Realty

  0 Ables Rd, Sikeston, MO 63801
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  /2

  $69,900

  • 2 Beds
  • 1 Bath
  • 1,204 Sq Ft

  334 E Kathleen St, Sikeston, MO 63801

  Christina Essner EXP Realty, LLC

  334 E Kathleen St, Sikeston, MO 63801
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  /2

  $106,000

  • Land
  • 0.86 Acre
  • $123,256 per Acre

  120 Cypress Branch Rd, Sikeston, MO 63801

  Greenfield North will be a gated, fenced cul-de-sac community located inside the city limits of Sikeston, just off Highway 61. You'll experience the convenience of town combined with the calm of a quiet neighborhood. Enjoy a private, secure location for your custom home. The covenants and restrictions were designed to help preserve property values and maintain a safe, high-quality, and

  Tim Merideth Century 21 Premiere Realty

  120 Cypress Branch Rd, Sikeston, MO 63801
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  /3

  $42,500

  • Land
  • 0.35 Acre
  • $121,429 per Acre

  408 Secretariat, Sikeston, MO 63801

  Welcome to Saddleridge South, 2nd Addition! Located inside the city limits of Sikeston, these lots have utilities already ran to them and are ready for construction to begin. You can be the general contractor, or we can introduce you to some of the area's finest builders to work with. Covenants and restrictions were crafted to help protect property value and are available upon request. These

  Tim Merideth Century 21 Premiere Realty

  408 Secretariat, Sikeston, MO 63801
• 

  

  /3

  $42,500

  • Land
  • 0.33 Acre
  • $128,788 per Acre

  403 Secretariat, Sikeston, MO 63801

  Welcome to Saddleridge South, 2nd Addition! Located inside the city limits of Sikeston, these lots have utilities already ran to them and are ready for construction to begin. You can be the general contractor, or we can introduce you to some of the area's finest builders to work with. Covenants and restrictions were crafted to help protect property value and are available upon request. These

  Tim Merideth Century 21 Premiere Realty

  403 Secretariat, Sikeston, MO 63801
• 

  /2

  $108,000

  • Land
  • 0.99 Acre
  • $109,091 per Acre

  110 Cypress Branch Rd, Sikeston, MO 63801

  Greenfield North will be a gated, fenced cul-de-sac community located inside the city limits of Sikeston, just off Highway 61. You'll experience the convenience of town combined with the calm of a quiet neighborhood. Enjoy a private, secure location for your custom home. The covenants and restrictions were designed to help preserve property values and maintain safe, high-quality, and comfortable

  Tim Merideth Century 21 Premiere Realty

  110 Cypress Branch Rd, Sikeston, MO 63801
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  /3

  $49,000

  • 2 Beds
  • 1 Bath
  • 976 Sq Ft

  115 William St, Sikeston, MO 63801

  Looking for a great investment opportunity. This home is it: nice size lot, detached shop/storage, a new roof in 2023, a new swing heat/cool unit and a few new windows. Home has original wood floors in living room and bedroom. Home needs to be redone in several of the rooms but definitely not a major overhaul. Make your appointment today and make this property your investment.

  Reida Kimes Century 21 Premiere Realty

  115 William St, Sikeston, MO 63801
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  /5

  $244,500

  • Land
  • 1.57 Acres
  • $155,732 per Acre

  1401 N Main St, Sikeston, MO 63801

  Located on Highway 61, on the northern edge of Sikeston City limits, this tract is situated on a high-traffic state route that connects Sikeston with the City of Sikeston Industrial Park and Sikeston campus of Southeast Missouri State University. It is adjacent to Greenbriar and Fairfield Subdivisions; two of the town's nice subdivisions. Zoning is C-1 Neighborhood Shopping District, which is for

  Tim Merideth Century 21 Premiere Realty

  1401 N Main St, Sikeston, MO 63801
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  /2

  $69,900

  • 2 Beds
  • 2 Baths
  • 1,008 Sq Ft

  118 N 3rd St, Sikeston, MO 63801

  Welcome to this 2-bedroom, 2-bath ranch home—a perfect choice for a starter home or someone looking to downsize! Enjoy the ease of single-level living with a functional layout and plenty of natural light throughout. The home includes a detached garage, offering extra storage or workspace potential. With its classic design and solid bones, this property is full of potential to make it your own.

  Christina Essner EXP Realty, LLC

  118 N 3rd St, Sikeston, MO 63801
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  /50

  $499,900

  • 3 Beds
  • 5 Baths
  • 5,296 Sq Ft

  243 N Ridge Rd, Sikeston, MO 63801

  Tucked at the edge of town in a quiet, well-kept neighborhood, this home has the kind of space and character that’s hard to find. Thoughtfully cared for and surrounded by mature landscaping and an established garden, it offers privacy, functionality, and room to grow.Upstairs features three spacious bedrooms, all with walk-in closets, plus two and a half baths. You'll find beautiful

  Sarah McKinney EXP Realty, LLC

  243 N Ridge Rd, Sikeston, MO 63801
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  /2

  $47,000

  • 3 Beds
  • 1 Bath
  • 1,309 Sq Ft

  1140 Ruth St, Sikeston, MO 63801

  If you are looking for an investment property or a home that requires some TLC, this home is ready for your renovations. Priced to sell quickly, schedule your viewing today!

  Thomas Williams Century 21 Premiere Realty

  1140 Ruth St, Sikeston, MO 63801
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  /2

  $15,000

  • Land
  • 0.2 Acre
  • $75,000 per Acre

  809 Bollweevil Blvd, Sikeston, MO 63801

  This vacant residential lot is ready for you to build on, and priced to help you get started quickly. Covenants and restrictions are in place to help protect your investment. Located inside Sikeston City Limits. Additional Rooms: In Platted Subdv.

  Tim Merideth Century 21 Premiere Realty

  809 Bollweevil Blvd, Sikeston, MO 63801
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  /7

  $174,900

  • 3 Beds
  • 1.5 Baths
  • 1,653 Sq Ft

  926 Crescent Dr, Sikeston, MO 63801

  This beautifully maintained all-brick hoe is nestled in a quiet, family-friendly neighborhood. It features 3 bedrooms, 1.5 baths, and a full basement with the potential for an additional bathroom. The interior boasts new laminate flooring throughout, and the roof was replaced in 2020, and the HVAC is 2 years old. Enjoy a spacious kitchen, with a double oven - perfect for cooking and entertaining

  Rene Church Century 21 Premiere Realty

  926 Crescent Dr, Sikeston, MO 63801
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  /2

  $59,900

  • 2 Beds
  • 1 Bath
  • 744 Sq Ft

  321 Benton St, Sikeston, MO 63801

  Investor Opportunity! This income-producing property offers solid potential with hardwood and tile floors throughout, combining durability with low-maintenance appeal. The fenced-in yard adds value for tenants seeking outdoor space, and the property's layout and location make it an attractive rental option. Whether you're expanding your portfolio or diving into your first investment, this is a

  Christina Essner EXP Realty, LLC

  321 Benton St, Sikeston, MO 63801
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  /6

  $198,900

  • 3 Beds
  • 2 Baths
  • 1,985 Sq Ft

  719 N West St, Sikeston, MO 63801

  Nice brick home with a family room added on the back. Wood burning fireplace. Huge walk in pantry. The bedrooms area ll good size. Master bath, unfinished basement perfect for storage.

  Ricki Ing Century 21 Ashland Realty

  719 N West St, Sikeston, MO 63801
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  /15

  $260,000

  • 3 Beds
  • 1.5 Baths
  • 2,034 Sq Ft

  106 Holmes Dr, Sikeston, MO 63801

  Spacious, modern, updated, extremely well appointed. Enter into a large living room plus a cozy family room at the back. Lots of natural light thru out. large eat in kitchen with island, all kitchen appliances stay including convection/air fryer oven and 2 pantry cabinets.. Vinyl plank flooring with new carpet in two bedrooms. Electric insert in the wood fireplace, the owner has never burned wood

  Linda Essner Century 21 Ashland Realty

  106 Holmes Dr, Sikeston, MO 63801
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  /2

  $48,000

  • 3 Beds
  • 2 Baths
  • 1,120 Sq Ft

  1205 W Murray Ln, Sikeston, MO 63801

  If you are looking for an investment property or a home that requires some TLC, this home is ready for your renovations. Priced to sell quickly, schedule your viewing today!

  Thomas Williams Century 21 Premiere Realty

  1205 W Murray Ln, Sikeston, MO 63801
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  /37

  $279,000

  • 3 Beds
  • 2 Baths
  • 2,113 Sq Ft

  907 Taylor St, Sikeston, MO 63801

  Welcome to 907 Taylor St in Sikeston — a spacious 3-bedroom, 2-bath brick home offering 2,113 sq ft of comfortable living space. Inside, you’ll find generously sized rooms perfect for both everyday living and entertaining. The home features a smart layout with large common areas, ideal for hosting or relaxing in comfort. Step outside to a well-maintained backyard complete with a workshop and

  Hunter Williams Century 21 Ashland Realty

  907 Taylor St, Sikeston, MO 63801
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  /8

  $98,900

  • 3 Beds
  • 1 Bath
  • 1,056 Sq Ft

  203 Russell Ave, Sikeston, MO 63801

  Tony McDonald McDonald Realty

  203 Russell Ave, Sikeston, MO 63801
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  /75

  $275,000

  • 3 Beds
  • 2 Baths
  • 1,295 Sq Ft

  511 S Kingshighway St, Sikeston, MO 63801

  Discover the perfect blend of timeless charm and contemporary luxury in this beautifully updated historical home. Featuring 3 spacious bedrooms, 2 full bathrooms, and an unfinished basement, this residence offers both character and comfort. Step inside to a light-filled interior adorned with gorgeous designer wallpaper, custom drapery, and thoughtful details that honor the home’s rich history.

  Lawren McMullan EDGE Realty, ERA Powered

  511 S Kingshighway St, Sikeston, MO 63801
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  /14

  $125,000

  • 3 Beds
  • 1 Bath
  • 1,080 Sq Ft

  318 Kendall St, Sikeston, MO 63801

  Welcome home to this fully remodeled 3-bedroom, 1-bath charmer, offering modern comfort and timeless style. Every detail has been thoughtfully updated, including fresh flooring, contemporary fixtures, new paint, and an inviting open layout that maximizes both light and space. All three bedrooms are generously sized, providing flexibility for family, guests, or a home office. The updated bathroom

  Lawren McMullan EDGE Realty, ERA Powered

  318 Kendall St, Sikeston, MO 63801
• 

  /2

  $74,500

  • 2 Beds
  • 1 Bath
  • 1,049 Sq Ft

  733 Matthews Ave, Sikeston, MO 63801

  Are you a first time homebuyer or looking to expand your investment portfolio? This cozy 2 bedroom home might be just for you! This home is located in a quiet neighborhood, yet is conveniently located close to shopping centers, schools, and both mid-town and downtown. This home offers an eat-in kitchen, laundry room and full bathroom with tub all that have been newly updated. This home is great

  Katrina Dowell C. Lawrence Realty LLC

  733 Matthews Ave, Sikeston, MO 63801

Showing Results 41 - 80, Page 2 of 4