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Sikeston, MO Homes for Sale

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  • /2

    $45,000

    • 2 Beds
    • 1 Bath
    • 1,335 Sq Ft

    420 Malcolm Ave, Sikeston, MO 63801

    If you are looking for an investment property or a home that requires some TLC, this home is ready for your renovations. Priced to sell quickly, schedule your viewing today!

    Thomas Williams Century 21 Premiere Realty

    420 Malcolm Ave, Sikeston, MO 63801
  • /38

    $344,500

    • 3 Beds
    • 3 Baths
    • 6,536 Sq Ft

    901 Moore Ave, Sikeston, MO 63801

    Do you like both indoor and outdoor space? This is the one for you. This home includes a large sunroom with ceiling fans located on the back of the house overlooking gorgeous landscaping. There's also outdoor space on the composite deck if you'd like a little sun. This nice brick home is on a corner lot in Sikeston's north end. Inside, the kitchen was recently remodeled with a nice island and

    Tim Merideth Century 21 Premiere Realty

    901 Moore Ave, Sikeston, MO 63801
  • /3

    $42,500

    • Land
    • 0.34 Acre
    • $125,000 per Acre

    404 Secretariat, Sikeston, MO 63801

    Welcome to Saddleridge South, 2nd Addition! Located inside the city limits of Sikeston, these lots have utilities already ran to them and are ready for construction to begin. You can be the general contractor, or we can introduce you to some of the area's finest builders to work with. Covenants and restrictions were crafted to help protect property value and are available upon request. These are

    Tim Merideth Century 21 Premiere Realty

    404 Secretariat, Sikeston, MO 63801
  • /4

    $195,000

    • Land
    • 0.72 Acre
    • $270,833 per Acre

    116 Hospitality Dr, Sikeston, MO 63801

    Vacant, level lot. Not in the flood plain.

    Larry Lindsey Century 21 Premiere Realty

    116 Hospitality Dr, Sikeston, MO 63801
  • /2

    $15,000

    • Land
    • 0.24 Acre
    • $62,500 per Acre

    810 Cotton Ridge Dr, Sikeston, MO 63801

    This vacant residential lot is ready for you to build on, and priced to help you get started quickly. Covenants and restrictions are in place to help protect your investment. Located inside Sikeston City Limits. Additional Rooms: In Platted Subdv.

    Tim Merideth Century 21 Premiere Realty

    810 Cotton Ridge Dr, Sikeston, MO 63801
  • /27

    $279,900

    • 3 Beds
    • 2 Baths
    • 1,946 Sq Ft

    829 Plantation Blvd, Sikeston, MO 63801

    Welcome to this beautiful 3-bedroom, 2-bath home located in a desirable Sikeston neighborhood! Step inside to an inviting open floor plan that seamlessly connects to the living, dining and kitchen areas-perfect for both everyday living and entertaining. The vaulted ceilings add an airy, spacious feel, while natural light fills the home throughout. The kitchen offers great functionality and flows

    Pam Dannenmueller EDGE Realty, ERA Powered

    829 Plantation Blvd, Sikeston, MO 63801
  • /4

    $15,000

    • Land
    • 0.16 Acre
    • $93,750 per Acre

    315 Jackson St, Sikeston, MO 63801

    Vacant residential lot ready for a buyer to build on. This is a 70 x 100 corner lot.

    Annie Harris Century 21 Premiere Realty

    315 Jackson St, Sikeston, MO 63801
  • /21

    $265,000

    • 3 Beds
    • 2.5 Baths
    • 1,774 Sq Ft

    1811 State Highway Z, Sikeston, MO 63801

    This 3 bedroom, 2.5 bath home offers the perfect blend of space, privacy, and convenience. Situated on just over an acre +/- outside of city limits, you can enjoy peaceful country living while still being less than a 10 minute drive to town. The spacious layout provides comfortable living with thoughtful updates throughout. A standout feature is the shop, which offers over a thousand square feet

    Rachel Sitzes Poplar Bluff Realty Inc

    1811 State Highway Z, Sikeston, MO 63801
  • /14

    $94,400

    • 2 Beds
    • 1 Bath
    • 1,000 Sq Ft

    406 W Gladys St, Sikeston, MO 63801

    Step inside this beautifully remodeled 2-bedroom, 1-bath home that’s move-in ready and full of modern updates! Fresh interior and exterior paint give the home a crisp, inviting look, while the brand-new flooring throughout adds warmth and style. Outside, the freshly painted exterior provides excellent curb appeal, and the manageable yard makes maintenance a breeze. Whether you’re a first-time

    Lawren McMullan EDGE Realty, ERA Powered

    406 W Gladys St, Sikeston, MO 63801
  • /9

    $100,000

    • 2 Beds
    • 1 Bath
    • 1,030 Sq Ft

    448 Crowe St, Sikeston, MO 63801

    TWO BEDROOM HOUSE LOCATED ON A LARGE CORNER LOT WITH 3 EXTRA VACANT LOTS INCLUDED, ALONG WITH TWO DETACHED SHOPS

    Tony McDonald McDonald Realty

    448 Crowe St, Sikeston, MO 63801
  • /2

    $90,000

    • 3 Beds
    • 1 Bath
    • 1,077 Sq Ft

    849 William St, Sikeston, MO 63801

    Enjoy entertaining in this 3-bedroom, 1-bath home with a spacious yard and separate dining room. Updates like the new dryer plug-in, baseboard heaters, fresh interior paint, kitchen cabinets, and sink add modern convenience while keeping maintenance low. Plus, the covered carport provides protected parking. Set up a showing today!

    Tasha Cardin EXP Realty, LLC

    849 William St, Sikeston, MO 63801
  • /3

    $42,500

    • Land
    • 0.39 Acre
    • $108,974 per Acre

    419 Secretariat, Sikeston, MO 63801

    Welcome to Saddleridge South, 2nd Addition! Located inside the city limits of Sikeston, these lots have utilities already ran to them and are ready for construction to begin. You can be the general contractor, or we can introduce you to some of the area's finest builders to work with. Covenants and restrictions were crafted to help protect property value and are available upon request. These are

    Tim Merideth Century 21 Premiere Realty

    419 Secretariat, Sikeston, MO 63801
  • /2

    $44,000

    • 4 Beds
    • 2 Baths
    • 1,300 Sq Ft

    408 Carroll St, Sikeston, MO 63801

    If you are looking for an investment property or a home that requires some TLC, this home is ready for your renovations. Priced to sell quickly, schedule your viewing today!

    Thomas Williams Century 21 Premiere Realty

    408 Carroll St, Sikeston, MO 63801
  • /14

    $3,960,000

    0 Ables Rd, Sikeston, MO 63801

    Located on the northwest corner of I-55 and I-57 inside Sikeston City limits, this ground is in a prime location for commercial development. This property can be accessed via Ables Road or County Line Road. Owner will subdivide into smaller tracts. There is power, water and sewer available, all provided by Sikeston Board of Municipal Utilities.

    Tim Merideth Century 21 Premiere Realty

    0 Ables Rd, Sikeston, MO 63801
  • /9

    $106,000

    • Land
    • 0.86 Acre
    • $123,256 per Acre

    120 Cypress Branch Rd, Sikeston, MO 63801

    Greenfield North will be a gated, fenced cul-de-sac community located inside the city limits of Sikeston, just off Highway 61. You'll experience the convenience of town combined with the calm of a quiet neighborhood. Enjoy a private, secure location for your custom home. The covenants and restrictions were designed to help preserve property values and maintain a safe, high-quality, and

    Tim Merideth Century 21 Premiere Realty

    120 Cypress Branch Rd, Sikeston, MO 63801
  • /3

    $42,500

    • Land
    • 0.35 Acre
    • $121,429 per Acre

    408 Secretariat, Sikeston, MO 63801

    Welcome to Saddleridge South, 2nd Addition! Located inside the city limits of Sikeston, these lots have utilities already ran to them and are ready for construction to begin. You can be the general contractor, or we can introduce you to some of the area's finest builders to work with. Covenants and restrictions were crafted to help protect property value and are available upon request. These are

    Tim Merideth Century 21 Premiere Realty

    408 Secretariat, Sikeston, MO 63801
  • /28

    $249,900

    • 3 Beds
    • 1.5 Baths
    • 1,782 Sq Ft

    109 Lynn St, Sikeston, MO 63801

    Welcome to 109 Lynn St. in Sikeston, located in the desirable Mini Farms subdivision - where space and comfort come together for family living. This 3-bedroom, 2-bathroom home offers two spacious living rooms, perfect for family movie nights, play areas, or hosting friends and relatives. Sitting on 1.62 acres, there is plenty of room for kids to play, pets to roam, and outdoor gatherings to

    Lauren DeWitt EDGE Realty, ERA Powered

    109 Lynn St, Sikeston, MO 63801
  • /60

    $475,000

    • 4 Beds
    • 4 Baths
    • 3,833 Sq Ft

    118 Greenbriar Dr, Sikeston, MO 63801

    Located on a desirable corner lot in one of the most sought-after neighborhoods on the north end of Sikeston, this meticulously maintained custom-built home (1988) offers exceptional space, craftsmanship, and distinctive features rarely found in today’s homes. With approximately 3,800 square feet of living space, the home features 4 bedrooms and 4 bathrooms, providing plenty of room for

    Stephanie Anderson SMG Realty

    118 Greenbriar Dr, Sikeston, MO 63801
  • /3

    $42,500

    • Land
    • 0.33 Acre
    • $128,788 per Acre

    403 Secretariat, Sikeston, MO 63801

    Welcome to Saddleridge South, 2nd Addition! Located inside the city limits of Sikeston, these lots have utilities already ran to them and are ready for construction to begin. You can be the general contractor, or we can introduce you to some of the area's finest builders to work with. Covenants and restrictions were crafted to help protect property value and are available upon request. These are

    Tim Merideth Century 21 Premiere Realty

    403 Secretariat, Sikeston, MO 63801
  • /9

    $108,000

    • Land
    • 0.99 Acre
    • $109,091 per Acre

    110 Cypress Branch Rd, Sikeston, MO 63801

    Greenfield North will be a gated, fenced cul-de-sac community located inside the city limits of Sikeston, just off Highway 61. You'll experience the convenience of town combined with the calm of a quiet neighborhood. Enjoy a private, secure location for your custom home. The covenants and restrictions were designed to help preserve property values and maintain safe, high-quality, and comfortable

    Tim Merideth Century 21 Premiere Realty

    110 Cypress Branch Rd, Sikeston, MO 63801
  • /2

    $69,900

    • 2 Beds
    • 2 Baths
    • 1,008 Sq Ft

    118 N 3rd St, Sikeston, MO 63801

    Welcome to this 2-bedroom, 2-bath ranch home—a perfect choice for a starter home or someone looking to downsize! Enjoy the ease of single-level living with a functional layout and plenty of natural light throughout. The home includes a detached garage, offering extra storage or workspace potential. With its classic design and solid bones, this property is full of potential to make it your own.

    Christina Essner EXP Realty, LLC

    118 N 3rd St, Sikeston, MO 63801
  • /2

    $45,000

    • 3 Beds
    • 1 Bath
    • 1,309 Sq Ft

    1140 Ruth St, Sikeston, MO 63801

    If you are looking for an investment property or a home that requires some TLC, this home is ready for your renovations. Priced to sell quickly, schedule your viewing today!

    Thomas Williams Century 21 Premiere Realty

    1140 Ruth St, Sikeston, MO 63801
  • /21

    $249,000 New Construction

    • 3 Beds
    • 2 Baths
    • 1,300 Sq Ft

    50 Byrd Dr, Sikeston, MO 63801

    Welcome to this stunning NEW construction home, thoughtfully designed with modern living in mind. This beautifully crafted residence features an open-concept floor plan that seamlessly connects the living, dining, and kitchen areas—perfect for both everyday living and entertaining. Offering 3 spacious bedrooms and 2 full bathrooms, the home provides comfort and functionality for a variety of

    Lawren McMullan EDGE Realty, ERA Powered

    50 Byrd Dr, Sikeston, MO 63801
  • /2

    $15,000

    • Land
    • 0.2 Acre
    • $75,000 per Acre

    809 Bollweevil Blvd, Sikeston, MO 63801

    This vacant residential lot is ready for you to build on, and priced to help you get started quickly. Covenants and restrictions are in place to help protect your investment. Located inside Sikeston City Limits. Additional Rooms: In Platted Subdv.

    Tim Merideth Century 21 Premiere Realty

    809 Bollweevil Blvd, Sikeston, MO 63801
  • /7

    $169,900

    • 3 Beds
    • 1.5 Baths
    • 1,653 Sq Ft

    926 Crescent Dr, Sikeston, MO 63801

    This beautifully maintained all-brick hoe is nestled in a quiet, family-friendly neighborhood. It features 3 bedrooms, 1.5 baths, and a full basement with the potential for an additional bathroom. The interior boasts new laminate flooring throughout, and the roof was replaced in 2020, and the HVAC is 2 years old. Enjoy a spacious kitchen, with a double oven - perfect for cooking and entertaining

    Rene Church Century 21 Premiere Realty

    926 Crescent Dr, Sikeston, MO 63801
  • /2

    $59,900

    • 2 Beds
    • 1 Bath
    • 744 Sq Ft

    321 Benton St, Sikeston, MO 63801

    Investor Opportunity! This income-producing property offers solid potential with hardwood and tile floors throughout, combining durability with low-maintenance appeal. The fenced-in yard adds value for tenants seeking outdoor space, and the property's layout and location make it an attractive rental option. Whether you're expanding your portfolio or diving into your first investment, this is a

    Christina Essner EXP Realty, LLC

    321 Benton St, Sikeston, MO 63801
  • /9

    $32,000

    • 2 Beds
    • 1 Bath
    • 1,116 Sq Ft

    405 Branum St, Sikeston, MO 63801

    Investor Special in Sikeston! Opportunity awaits at 405 Branum St. This property has been partially gutted and is ready for your vision to bring it back to life. Major demo work has already been completed, saving you time and upfront labor. Whether you’re looking for your next fix-and-flip project, rental property, or long-term hold, this is a blank canvas with serious upside potential.

    Jonathan Adams Keller Williams Realty West

    405 Branum St, Sikeston, MO 63801
  • /2

    $48,000

    • 3 Beds
    • 2 Baths
    • 1,120 Sq Ft

    1205 W Murray Ln, Sikeston, MO 63801

    If you are looking for an investment property or a home that requires some TLC, this home is ready for your renovations. Priced to sell quickly, schedule your viewing today!

    Thomas Williams Century 21 Premiere Realty

    1205 W Murray Ln, Sikeston, MO 63801
  • /2

    $74,900

    • 3 Beds
    • 1 Bath
    • 1,252 Sq Ft

    512 S New Madrid St, Sikeston, MO 63801

    Great opportunity for investors! This 3-bedroom property offers solid potential as a rental or flip, with a manageable layout and room to add value. Whether you're expanding your portfolio or getting started in real estate, this is a smart, affordable option. Don't miss out on this income-producing opportunity—schedule a showing today to see the possibilities!

    Christina Essner EXP Realty, LLC

    512 S New Madrid St, Sikeston, MO 63801
  • /3

    $42,500

    • Land
    • 0.46 Acre
    • $92,391 per Acre

    311 Citation Dr, Sikeston, MO 63801

    Come see Sikeston's newest subdivision! These are excellent sites for first-time home buyers, families, or those wanting to downsize. Turn south off Broadway onto South Illinois Avenue to two new cul-de-sacs, ensuring reduced traffic. This subdivision is inside Sikeston City limits, and has covenants and restrictions to help protect your investment. Super easy, fast access to Highway 60 and

    Tim Merideth Century 21 Premiere Realty

    311 Citation Dr, Sikeston, MO 63801
  • /12

    $264,000

    • 3 Beds
    • 2 Baths
    • 1,965 Sq Ft

    402 Garner St, Sikeston, MO 63801

    FIRST TIME ON THE MARKET !CUSTOM BUILT, ONE OWNER HOME, OPEN FLOOR PLAN WITH CUSTOM CABINETS, FLOORING , HUGE WALK IN SHOWER, INCLOSED SUNROOM ,ALL SITTING ON A LARGE CORNER LOT IN THE WESTVIEW SUBDIVISION AND SIKESTON SCHOOL DISTRICT .

    Tony McDonald McDonald Realty

    402 Garner St, Sikeston, MO 63801
  • /2

    $15,000

    • Land
    • 0.24 Acre
    • $62,500 per Acre

    804 Cotton Ridge Dr, Sikeston, MO 63801

    This vacant residential lot is ready for you to build on, and priced to help you get started quickly. Covenants and restrictions are in place to help protect your investment. Located inside Sikeston City Limits. Additional Rooms: In Platted Subdv.

    Tim Merideth Century 21 Premiere Realty

    804 Cotton Ridge Dr, Sikeston, MO 63801
  • /27

    $149,900

    • 1 Bed
    • 1 Bath
    • 986 Sq Ft

    1300 N Main St Unit 204, Sikeston, MO 63801

    LUXURY LIVING REDEFINED at Maingate Condominiums. Experience the perfect blend of security, style, and sophistication in this rarely available one bedroom executive condo. Located in Sikeston‘s premier gated community, unit 204 has been upgraded with new flooring, light fixtures, fresh paint and kitchen upgrades to make this a turnkey lifestyle for the new owner. Step inside to an open-concept

    Reida Kimes Century 21 Premiere Realty

    1300 N Main St Unit 204, Sikeston, MO 63801
  • /2

    $44,900

    • 2 Beds
    • 1.5 Baths
    • 576 Sq Ft

    136 N 6th St, Sikeston, MO 63801

    Great opportunity for investors! This 2-bedroom property offers solid potential as a rental or flip, with a manageable layout and room to add value. Whether you're expanding your portfolio or getting started in real estate, this is a smart, affordable option.

    Christina Essner EXP Realty, LLC

    136 N 6th St, Sikeston, MO 63801
  • /3

    $42,500

    • Land
    • 0.32 Acre
    • $132,812 per Acre

    414 Secretariat, Sikeston, MO 63801

    Welcome to Saddleridge South, 2nd Addition! Located inside the city limits of Sikeston, these lots have utilities already ran to them and are ready for construction to begin. You can be the general contractor, or we can introduce you to some of the area's finest builders to work with. Covenants and restrictions were crafted to help protect property value and are available upon request. These are

    Tim Merideth Century 21 Premiere Realty

    414 Secretariat, Sikeston, MO 63801
  • /11

    $169,900

    • 4 Beds
    • 2 Baths
    • 2,101 Sq Ft

    502 Jaycee St, Sikeston, MO 63801

    This well-maintained four-bedroom, two-bath home offers plenty of room to grow, plus a versatile bonus space that can serve as a fifth bedroom, home office, playroom, or anything you envision. Situated on a desirable corner lot, the property features a fully fenced backyard—perfect for pets, gardening, or outdoor entertaining. Step inside to a warm and inviting layout, beginning with an eat-in

    Scott Harrison Delta Realty, LLC

    502 Jaycee St, Sikeston, MO 63801
  • /26

    $164,000

    • 3 Beds
    • 1.5 Baths
    • 1,702 Sq Ft

    701 Sikes Ave, Sikeston, MO 63801

    Jakahran Johnson EDGE Realty ERA Powered

    701 Sikes Ave, Sikeston, MO 63801
  • /9

    $106,000

    • Land
    • 0.81 Acre
    • $130,864 per Acre

    130 Cypress Branch Rd, Sikeston, MO 63801

    Greenfield North will be a gated, fenced cul-de-sac community located inside the city limits of Sikeston, just off Highway 61. You'll experience the convenience of town combined with the calm of a quiet neighborhood. Enjoy a private, secure location for your custom home. The covenants and restrictions were designed to help preserve property values and maintain a safe, high-quality, and

    Tim Merideth Century 21 Premiere Realty

    130 Cypress Branch Rd, Sikeston, MO 63801
  • /2

    $400,000

    • Land
    • 2.63 Acres
    • $152,091 per Acre

    109 Stallcup Dr, Sikeston, MO 63801

    Over 2.5 acres of commercial property located in the heart of Sikeston's booming retail and hospitality area. Just a block from Wal-Mart Supercenter, 2 new hotels, shopping and restaurants, and a half mile to the intersection of US Highways 60 & 61. This is a premium location at an outstanding price.

    Tim Merideth Century 21 Premiere Realty

    109 Stallcup Dr, Sikeston, MO 63801
  • /3

    $42,500

    • Land
    • 0.14 Acre
    • $303,571 per Acre

    406 Aster, Sikeston, MO 63801

    Welcome to Saddleridge South, 2nd Addition! Located inside the city limits of Sikeston, these lots have utilities already ran to them and are ready for construction to begin. You can be the general contractor, or we can introduce you to some of the area's finest builders to work with. Covenants and restrictions were crafted to help protect property value and are available upon request. These are

    Tim Merideth Century 21 Premiere Realty

    406 Aster, Sikeston, MO 63801

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