28

Defiance, MO Homes for Sale

Section Image
  • /48

    $699,900

    • 5 Beds
    • 4.5 Baths
    • 4,140 Sq Ft

    3856 Rooster Ridge Ln, Defiance, MO 63341

    Prepare to be WOWED! Impressive 1.5 story on a 3.2 AC, wooded lot for nature-loving buyers who enjoy the outdoors. This peaceful setting creates a picturesque back-drop for an amazing home. The ext is impressive w/brick, 4 bay windows, 3 car gar, arch shingles (1 yr old), leaded glass door and a large front porch. Features inc 4,140 s/f of living space, 5 BD, 4.5 BA, 2 story Grt Rm w/window wall,

    Kelly Boehmer Berkshire Hathaway HomeServices Select Properties

    3856 Rooster Ridge Ln, Defiance, MO 63341
  • /46

    $559,000

    • 4 Beds
    • 3 Baths
    • 2,978 Sq Ft

    8 Lost Trails Dr, Defiance, MO 63341

    PRICE IMPROVED!!! Discover your dream home in the exclusive Callaway Valley, a hidden gem in St. Charles County. This enchanting log cabin combines rustic charm with modern luxury on 3.6 wooded acres. Warm wood tones, exposed beams, and an open floor plan perfect for family living and entertaining. Updated kitchen with granite countertops and stainless steel appliances. Two cozy fireplaces.

    Suzanne Matyiko Berkshire Hathaway HomeServices Alliance Real Estate

    8 Lost Trails Dr, Defiance, MO 63341
  • /3

    $161,920

    • Land
    • 5 Acres
    • $32,000 per Acre

    120 Steeple Point Dr Lot #13 Dr, Defiance, MO 63341

    Another Great Lot in the Steeple Point Subdivision. Schedule your appointment to view today.

    Dan Lauderdale Lauderdale Realty

    120 Steeple Point Dr Lot #13 Dr, Defiance, MO 63341
  • /3

    $248,920

    • Land
    • 9 Acres
    • $28,000 per Acre

    110 Steeple Point Dr Lot # 14 Dr, Defiance, MO 63341

    WOW, nearly 9 acres for under $250,000. Schedule an appointment and view this lot today.

    Dan Lauderdale Lauderdale Realty

    110 Steeple Point Dr Lot # 14 Dr, Defiance, MO 63341
  • /9

    $161,600

    • Land
    • 5 Acres
    • $32,000 per Acre

    130 Steeple Point Dr Lot #12 Dr, Defiance, MO 63341

    Great Building Lot. Schedule an appointment and view this property today.

    Dan Lauderdale Lauderdale Realty

    130 Steeple Point Dr Lot #12 Dr, Defiance, MO 63341
  • /5

    $164,160

    • Land
    • 5 Acres
    • $32,000 per Acre

    150 Steeple Point Dr Lot #10 Dr, Defiance, MO 63341

    Gorgeous Lot in Steeple Point. Great views and quite living.

    Dan Lauderdale Lauderdale Realty

    150 Steeple Point Dr Lot #10 Dr, Defiance, MO 63341
  • /2

    $300,160

    • Land
    • 11 Acres
    • $28,000 per Acre

    190 Steeple Point Dr Lot #6 Dr, Defiance, MO 63341

    Great home site in a rural setting.

    Dan Lauderdale Lauderdale Realty

    190 Steeple Point Dr Lot #6 Dr, Defiance, MO 63341
  • /7

    $160,960

    • Land
    • 5 Acres
    • $32,000 per Acre

    180 Steeple Point Dr Lot #7 Dr, Defiance, MO 63341

    Awesome lot available in a rural subdivision

    Dan Lauderdale Lauderdale Realty

    180 Steeple Point Dr Lot #7 Dr, Defiance, MO 63341
  • /35

    $210,000

    • Land
    • 1.23 Acres
    • $170,732 per Acre

    1462 Highway Dd, Defiance, MO 63341

    A truly unique property with endless possibilities! Just use your imagination and see what happens! This 1.2 acre lot has an older utility building with storage space, garage spaces for storage, a large workshop and a partial underground storage space with gravel floor and large access doors. There are several partially finished rooms/offices, sinks and 2 bathrooms. Some rooms have baseboard

    Chad Matlick Coldwell Banker Realty - Gundaker

    1462 Highway Dd, Defiance, MO 63341
  • /39

    $399,900

    • 3 Beds
    • 2 Baths
    • 2,028 Sq Ft

    41 Greenview Dr, Defiance, MO 63341

    Attention Investors and Rehabbers!! This is an AS IS Sale. Seller to do no repairs, warranties or inspections. This is a great opportunity to add your own finishing touches to this home on 3.69 beautiful wooded acres in the tranquil Callaway Farms Subdivision in Defiance. This home features a large kitchen, large family room with fireplace, separate dining room and three bedrooms. The master

    Kim Slaughter Realty Resource Partners, LLC

    41 Greenview Dr, Defiance, MO 63341
  • /26

    $700,000

    • 4 Beds
    • 4 Baths
    • 3,898 Sq Ft

    2347 Callaway Fork Rd, Defiance, MO 63341

    Experience serene country living on this stunning 7.5-acre property! This beautifully maintained 3-bedroom, 4-bathroom home features soaring vaulted ceilings, rich wood floors, and a custom kitchen perfect for entertaining. Step outside to a spacious deck with a charming gazebo—ideal for relaxing or hosting guests. The finished lower level offers even more living space with a sleeping area,

    Katrina Van Dillen Berkshire Hathaway HomeServices Select Properties

    2347 Callaway Fork Rd, Defiance, MO 63341
  • /6

    $649,900

    • Land
    • 10 Acres
    • $64,990 per Acre

    151 Matson Hill Rd, Defiance, MO 63341

    Welcome to an extraordinary land opportunity in Missouri Wine Country. Perched high on the bluffs above the Missouri River, this breathtaking 10-acre estate offers incredible views that stretch across the rolling countryside—an unmatched backdrop for your dream home, luxury retreat, or next big vision. Located just three miles south of Defiance, this property sits at the epicenter of elegance and

    Ryan Zimmer Coldwell Banker Realty - Gundaker

    151 Matson Hill Rd, Defiance, MO 63341
  • /21

    $475,000

    • 4 Beds
    • 3 Baths
    • 2,847 Sq Ft

    5 Cedar Fork Ct, Defiance, MO 63341

    Looking for acreage in St. Charles County? Your search ends here! Don’t miss this 4BR/3BA hidden gem perfectly situated on a 3-acre lot in Defiance, providing a tranquil retreat. The wrap-around deck offers endless outdoor relaxation. Inside, large windows connect the indoors to the surrounding beauty. The vaulted living room features a cozy wood burning FP, and the kitchen includes a peninsula,

    Chad Matlick Coldwell Banker Realty - Gundaker

    5 Cedar Fork Ct, Defiance, MO 63341
  • /57

    $1,399,000

    • 3 Beds
    • 5 Baths
    • 2,436 Sq Ft

    4075 Highway D, Defiance, MO 63341

    More details to come. This is a must see!!! This beautifully updated, well maintained home with 3 beds, (3) full (2) 1/2 baths is on 10 flat acres. Primary bedroom has a bay window, separate shower/jacuzzi tub. Family room has a wood burning fireplace. Relax 0on the covered porch that overlooks a water feature and the lake. Kitchen has granite countertops, propane cooktop, double ovens. double

    John Shaw Tom Shaw, REALTORS

    4075 Highway D, Defiance, MO 63341
  • /53

    $480,000

    • 4 Beds
    • 4 Baths
    • 2,864 Sq Ft

    6 Cedar Fork Ct, Defiance, MO 63341

    Welcome to this charming 4 bed, 4 bath home nestled on 3 acres in the sought-after Francis Howell school district! Step inside and be captivated by the soaring floor to ceiling windows, creating a spacious feel that’s perfect for entertaining or nestling by the fireplace. The kitchen features ample storage, beautiful granite countertops and an inviting eat-in area with year-round views of a

    Terra Treece Epique Realty

    6 Cedar Fork Ct, Defiance, MO 63341
  • /3

    $325,000

    • Land
    • 5.00 Acres
    • $65,000 per Acre

    513 Callaway Estates Dr Unit 5 acres, Defiance, MO 63341

    Welcome to The Estates at Callaway Lake, an exclusive luxury subdivision nestled in the serene countryside of unincorporated Saint Charles County, Missouri. This prestigious community offers 108 breathtaking lots, ranging from 5 to 15 acres, providing the perfect canvas for your custom dream home. With a minimum build requirement of 2,400 sq. ft. and architectural approval, each estate combines

    Tom Shaw Tom Shaw, REALTORS

    513 Callaway Estates Dr Unit 5 acres, Defiance, MO 63341
  • /6

    $205,000

    • Land
    • 3.01 Acres
    • $68,106 per Acre

    121 Red Barn Ln, Defiance, MO 63341

    Your plans, your builder. Level, open lot with woods along the back line. The last unbuilt lot remaining. One of only (9) lots in Femme Osage Valley subdivision. Public water. Blacktop Streets. 10 minutes from Hwy 40/61. Additional Rooms: In Platted Subdv.

    John Shaw Tom Shaw, REALTORS

    121 Red Barn Ln, Defiance, MO 63341
  • /60

    $389,900

    • 3 Beds
    • 2 Baths
    • 2,469 Sq Ft

    3930 Highway D, Defiance, MO 63341

    PRICE IMPROVEMENTS MADE! Home is being sold "as is". Price has been reduced to allow buyer to make improvements/updates to the property. MOVE RIGHT INTO THIS 2.5 ACRE 2 STORY CONVENIENTLY LOCATED JUST MINUTES FROM WINERIES, SCHOOLS, SHOPPING & HIGHWAYS! PRICED TO SELL! Step into gleaming HARDWOOD FLOORING IN ENTRY & DINING RM! Perfect HOME OFFICE/FLEX RM flanks other side of foyer. Cozy family

    Vittorio Donati RE/MAX EDGE

    3930 Highway D, Defiance, MO 63341
  • /21

    $485,000

    • 3 Beds
    • 2 Baths
    • 1,705 Sq Ft

    5 Wilderness Ln, Defiance, MO 63341

    Just imagine, a private home on 3 acres with a composite deck to enjoy the yard. Walking inside you find gleaming hardwood flooring. The family room has a wood burning fireplace with a circulating blower. Windows through the home have between-the-glass blinds to provide privacy. Kitchen boast a double oven. Many closets in the home have closet systems to provide for organization. Basement is

    Bradley Hanewinkel NextHome Simple Transitions

    5 Wilderness Ln, Defiance, MO 63341
  • /24

    $419,900

    • 4 Beds
    • 1 Bath
    • 1,321 Sq Ft

    130 Defiance Rd, Defiance, MO 63341

    Charming rustic farmhouse in excellent condition, nestled in the heart of downtown Defiance. This home offers stunning views of the Missouri River bottoms from the front porch, providing a serene and picturesque setting. Ideal for a short-term rental investment or as a cozy permanent residence. With its well-preserved character and prime location, this property offers both comfort and potential

    Tony Schulte MO Realty

    130 Defiance Rd, Defiance, MO 63341
  • /19

    $400,000

    • 2 Beds
    • 1 Bath
    • 1,728 Sq Ft

    112 Defiance Rd, Defiance, MO 63341

    A prime commercial space in the heart of downtown Defiance, featuring a beautifully renovated 1,728 sq ft building, formerly used as a kitchen and catering house. This property offers endless possibilities for various business ventures. The building boasts a poured foundation basement, providing ample storage space. Outdoors, you'll find a spacious pavilion with a stunning stone fireplace,

    Tony Schulte MO Realty

    112 Defiance Rd, Defiance, MO 63341
  • /17

    $219,900

    • Land
    • 14 Acres
    • $15,378 per Acre

    0 Steeple Rock Unit MAR24075687, Defiance, MO 63341

    Beautiful building lot St. Charles County area of Defiance! All wooded with grand rock outcroppings and mature timber! Come build your dream home on the ridge overlooking the wooded valley and draws below. The drive coming down Callaway Fork Road is breathtaking as well. Where else in St. Charles County can you find 14+ Acres to call your own at this price and located in the Francis Howell School

    Eric Merchant Trophy Properties & Auction

    0 Steeple Rock Unit MAR24075687, Defiance, MO 63341
  • /3

    $325,000

    • Land
    • 5.00 Acres
    • $65,000 per Acre

    503 Callaway Estates Dr Unit 5 acres, Defiance, MO 63341

    Welcome to The Estates at Callaway Lake, an exclusive luxury subdivision nestled in the serene countryside of unincorporated Saint Charles County, Missouri. This prestigious community offers 108 breathtaking lots, ranging from 5 to 15 acres, providing the perfect canvas for your custom dream home. With a minimum build requirement of 2,400 sq. ft. and architectural approval, each estate combines

    Tom Shaw Tom Shaw, REALTORS

    503 Callaway Estates Dr Unit 5 acres, Defiance, MO 63341
  • /5

    $684,320

    26 Callaway Ridge Dr, Defiance, MO 63341

    Discover your private oasis on this rare 28.1-acre parcel in the sought-after Callaway Valley Subdivision! Perfect for your dream home or personal estate, this expansive property offers serene seclusion amidst lush nature, with the flexibility to create up to four ideal building sites. Surrounded by custom homes on private roads and located within the highly regarded Francis Howell School

    Suzanne Matyiko Berkshire Hathaway HomeServices Alliance Real Estate

    26 Callaway Ridge Dr, Defiance, MO 63341
  • /13

    $165,440

    • Land
    • 5 Acres
    • $32,000 per Acre

    160 Steeple Point Dr Lot #9 Dr, Defiance, MO 63341

    Dan Lauderdale Lauderdale Realty

    160 Steeple Point Dr Lot #9 Dr, Defiance, MO 63341
  • /68

    $1,150,000 Coming Soon

    • 5 Beds
    • 6.5 Baths
    • 6,687 Sq Ft

    848 Golden Meadows Dr, Defiance, MO 63341

    Stunning, custom built home in Defiance on 3.64 level acres. This 1.5 sty includes TWO primary suites. Main floor 1100 SF primary suite w/ fireplace, walk-in designer closet, coffee/wine bar & direct access to the basement. Primary bath w/ a walk-in shower & double vanity sinks. Great Room features cathedral ceilings and Palladian windows. Kitchen includes 42" white cabinets, granite

    Megan Kaup SCHNEIDER Real Estate

    848 Golden Meadows Dr, Defiance, MO 63341
  • /51

    $825,000 Open Sat 1PM - 3PM

    • 3 Beds
    • 4 Baths
    • 4,065 Sq Ft

    140 Norfork Ct, Defiance, MO 63341

    Experience refined living in this exceptional reverse 1.5-story estate nestled in Defiance, within the highly acclaimed Francis Howell Schools. Thoughtfully designed for both elegance & comfort, this residence showcases timeless travertine in the grand foyer & gleaming hardwood floors that flow through a sun-drenched living & dining space with soaring ceilings & a wood-burning fireplace, all

    Jeremy Barrett Keller Williams Realty West

    140 Norfork Ct, Defiance, MO 63341
  • /5

    $325,000

    • Land
    • 5.00 Acres
    • $65,000 per Acre

    513 Callaway Estates Dr, Defiance, MO 63341

    Welcome to Callaway Lake Estates, an exclusive luxury subdivision nestled in the serene countryside of unincorporated Saint Charles County, Missouri. This prestigious community offers 108 breathtaking lots, ranging from 5 to 15 acres, providing the perfect canvas for your custom dream home. With a minimum build requirement of 2,400 sq. ft. and architectural approval, each estate combines elegance

    Toni Dillon Tom Shaw, REALTORS

    513 Callaway Estates Dr, Defiance, MO 63341

Why Live in Defiance

The gateway to Missouri wine country begins in the green hills of Defiance. Not actually a city, Defiance is an unincorporated community in southwest St. Charles County, where farms, vineyards and pastoral estates are spread among the sparsely populated region of 3,200 residents.

Though residential construction is spilling into the area from other parts of the county, a defining factor of Defiance real estate remains the expansive lots that homes sit on, which Lauderdale Realty owner Dan Lauderdale says typically are 5 acres or larger, thou ...

Frequently Asked Questions

What is the average home price in Defiance, MO?
Homes for sale in Defiance, MO have an average home price of $743,387.
Are home prices dropping in Defiance?
Yes, home prices in Defiance are down 14% in the last 12 months.
How many homes have sold over the last 12 months in Defiance, MO?
37 homes have sold in Defiance, MO over the last 12 months.
What are the most popular zip codes in Defiance, MO?
The most popular zip codes in Defiance, MO include 63385, 63366, 63348, 63390 and 63368.
How much do you need to make to afford a house in Defiance?
The median home price in Defiance is $627,450. If you put a 20% down payment of $125,500 and had a 30-year fixed mortgage with an interest rate of 6.84%, your estimated principal and interest payment would be $3,290 a month plus property taxes, HOA fees, home insurance, PMI, and utilities. Using the 28% rule, you would need to make at least $141K a year to afford the median home price in Defiance.
How are the schools in Defiance, MO?
Defiance, MO has highly rated public and private schools. Some of the best schools in Defiance based on Niche Grades are Francis Howell High School, Daniel Boone Elementary School and Francis Howell Middle School. Browse all the schools in Defiance, MO to learn more.

Home Trends in Defiance, MO

Housing Trends

Median Sale Price
$680,000
Median Single Family Sale Price
$628,950
Average Price Per Sq Ft
$242
Number of Homes for Sale
13
Last 12 months Home Sales
37
Months of Supply
4.20
Median List Price
$627,450
Median Change From 1st List Price
3%
Median Home Sale Price YoY Change
7%
How to Buy a Home How to Finance a Home How to Sell a Home