Defiance, MO Homes for Sale

Q: What are the most popular zip codes in Defiance, MO?

The most popular zip codes in Defiance, MO include 63341 , 63073 , 63005 , 63348 and 63332 .

/62
$775,000
- 3 Beds
- 3.5 Baths
- 5,601 Sq Ft
3840 Rooster Ridge Ln, Defiance, MO 63341

LOCATION is perfection! Travel down a paved road and arrive at your custom ranch home, with double garages, a finished basement, stunning seller/builder details with over 5,000 total finished SF! I need way more space here to describe all of the features. Large kitchen with second dining / living area arranged around the Buck stove fireplace. Brazilian cherry flooring, double wall ovens, long

Hope Fick

Sage Property Group, LLC

(636) 556-4474

3840 Rooster Ridge Ln, Defiance, MO 63341
Explore Defiance
/19
$325,000
- Land
- 5.03 Acres
- $64,612 per Acre
3077 S Highway 94 (5 03+ - Acres), Defiance, MO 63341

5.03 acre homesite with exceptional Missouri River Valley views just outside the heart of Defiance. This scenic property offers a rare opportunity to build your home where the landscape opens to sweeping countryside views and beautiful sunrise exposure over the valley. The property features a PRIVATE Lane with direct access to Hwy 94, providing convenient access while maintaining a peaceful

Meyer Auctions Meyer & Company Real Estate and Auctions

3077 S Highway 94 (5 03+ - Acres), Defiance, MO 63341
/3
$199,900
- Land
- 3.45 Acres
- $57,942 per Acre
0 Defiance Rd Unit 22755774, Defiance, MO 63341

This expansive 3.45-acre lot is ideally situated in the heart of downtown Defiance, offering a rare combination of space and convenience. The property features a charming, rustic red barn that adds a touch of character and potential for various uses, from storage to creative projects. The ample size of the lot provides plenty of room for development, gardening, or outdoor activities. With its

MO Realty MO Realty

0 Defiance Rd Unit 22755774, Defiance, MO 63341
/89
$1,450,000
- 3 Beds
- 5 Baths
- 3,974 Sq Ft
4500 Hueffmeier Rd, Defiance, MO 63341

Double Mustang Ranch — a 15-acre equestrian estate set among rolling hills and surrounding horse properties, where refined living meets a fully developed, turnkey equestrian setup designed for both lifestyle and function. Set behind a long private drive and framed by classic white equestrian fencing, the property delivers the setting buyers seek but rarely find. Just minutes from Broemmelsiek

Christine Williams Coldwell Banker Realty - Gundaker

4500 Hueffmeier Rd, Defiance, MO 63341
/43
$1,499,000
- 4 Beds
- 3.5 Baths
- 4,461 Sq Ft
115 Markham Trail Ln, Defiance, MO 63341

Looking for the perfect multi-generational home or private in-law suite with its own entrance? This custom-built Lombardo Ranch on 5.44 acres checks every box. Thoughtfully designed with high-end upgrades throughout, this home blends style, comfort, and function in every detail.On the main level, you’ll find a chef’s kitchen featuring white custom cabinetry, quartz countertops, a striking

Madison Lantz Berkshire Hathaway HomeServices Select Properties

115 Markham Trail Ln, Defiance, MO 63341
/80
$1,350,000 Coming Soon
- 4 Beds
- 5.5 Baths
- 5,087 Sq Ft
3817 Indian Ridge Ln, Defiance, MO 63341

Tucked away on over 3 acres, this exceptional custom estate offers a rare blend of privacy, luxury, and resort-style living. Expansive indoor spaces and exceptional outdoor amenities create a true retreat defined by privacy and natural surroundings. A grand entry with soaring 18-foot ceilings create an immediate sense of arrival, flanked by a private office with custom built-ins and a formal

Laura Sanders Compass Realty Group

3817 Indian Ridge Ln, Defiance, MO 63341
/98
$1,389,000 New Construction
- 5 Beds
- 5.5 Baths
- 5,504 Sq Ft
170 Blue Sky, Defiance, MO 63341

Brand new custom-built home on 3+ wooded acres in Kohler Estates subdivision. Features 4 bedrooms and 5 1/2 baths, a oversized 4 car garage with stair access to basement, a Great Room with a stone gas fireplace, with custom bookshelves, Gourmet kitchen offers custom cabinetry with quartz countertops, tile backsplash, and a complete appliance package, and walk-in pantry with custom shelving.

Chris Dawson Orenda Real Estate Services

170 Blue Sky, Defiance, MO 63341
/4
$587,000
- Land
- 5.87 Acres
- $100,000 per Acre
4 Cooper's Ct, Defiance, MO 63341

Nestled in the heart of St. Charles County near Defiance and New Melle, MO, Callaway Lake Estates offers a rare opportunity to build your dream home surrounded by natural beauty while remaining close to modern conveniences. This private community is designed for those seeking space, recreation, and long-term value. The development features 108 homesites, with 35 already sold in the first 18

Toni Dillon Trophy Properties & Auction

4 Cooper's Ct, Defiance, MO 63341
/4
$279,900
- Land
- 5 Acres
- $55,980 per Acre
5011 Lily Ridge, Defiance, MO 63341

Sunset Estates in St. Charles County MO. Four Luxurious home sites, on 5 acre lots. Located in the heart of Defiance and wine country. Bring your own builder/plans and build your dream home on one of these premium secluded, all wooded lots. Homesites are located on a private street with cul-de-sac. Homeowners will enjoy the peace and quiet, along with privacy. County water and high-speed

Bill McNair II First American Real Estate Co.

5011 Lily Ridge, Defiance, MO 63341
/2
$485,000 Coming Soon
- Land
- 9.05 Acres
- $53,591 per Acre
2461 Highway F, Defiance, MO 63341

This mostly level 9.05 Acres of land includes a well with a solar-powered pump and five frost-free spigots on the southeast side—perfect for gardens, orchards, or hobby farming. A gravel driveway has already been added along the south side for convenient access. Only a small portion of the front is in the 100-year floodplain, while the majority of the property sits outside of it, giving you

Catherine Shaw-Connely Tom Shaw, REALTORS

2461 Highway F, Defiance, MO 63341
/4
$151,000
- Land
- 5.03 Acres
- $30,020 per Acre
180 Steeple Point Dr Lot #7 Dr, Defiance, MO 63341

Awesome lot available in a rural subdivision

Dan Lauderdale Lauderdale Realty

180 Steeple Point Dr Lot #7 Dr, Defiance, MO 63341
/30
$949,900
- 4 Beds
- 5 Baths
- 2,436 Sq Ft
4075 Highway D, Defiance, MO 63341

NOT IN A SUBDIVISION, NO INDENTURES OR RESTRICTIONS!!!! NEW ROOF.This is a must see!!! This beautifully updated, well maintained home with 3 beds, (3) full (2) 1/2 baths is on 10 flat acres. Primary bedroom has a bay window, separate shower/jacuzzi tub. Family room has a wood burning fireplace. Relax on the covered porch that overlooks a water feature and the lake. Kitchen has granite

John Shaw Tom Shaw, REALTORS

4075 Highway D, Defiance, MO 63341
/9
$151,000
- Land
- 5.05 Acres
- $29,901 per Acre
130 Steeple Point Dr Lot #12 Dr, Defiance, MO 63341

Great Building Lot. Schedule an appointment and view this property today.

Dan Lauderdale Lauderdale Realty

130 Steeple Point Dr Lot #12 Dr, Defiance, MO 63341
/2
$152,000
- Land
- 5.06 Acres
- $30,040 per Acre
120 Steeple Point Dr Lot #13 Dr, Defiance, MO 63341

Another Great Lot in the Steeple Point Subdivision. Schedule your appointment to view today.

Dan Lauderdale Lauderdale Realty

120 Steeple Point Dr Lot #13 Dr, Defiance, MO 63341
/97
$695,000 Open Sun 2PM - 4PM
- 3 Beds
- 2.5 Baths
- 2,852 Sq Ft
51 Nordic Ln, Defiance, MO 63341

Welcome to your dream home - a stunning, cozy, country home nestled in the middle of the woods on 3 acres. This home is an oasis located in St. Charles County wine country, minutes from some of St. Charles ’best hiking & biking trails! This outdoor play scape was designed with the outdoors lover in mind and has ample green-space to enjoy. This remarkable property features an inviting inground

Mary Bay Coldwell Banker Realty - Gundaker

51 Nordic Ln, Defiance, MO 63341
/2
$238,900
- Land
- 8.89 Acres
- $26,873 per Acre
110 Steeple Point Dr Lot # 14 Dr, Defiance, MO 63341

WOW, nearly 9 acres for under $250,000. Schedule an appointment and view this lot today.

Dan Lauderdale Lauderdale Realty

110 Steeple Point Dr Lot # 14 Dr, Defiance, MO 63341
/22
$299,000
- Land
- 5.03 Acres
- $59,443 per Acre
3077 S Missouri 94, Defiance, MO 63341

A truly rare opportunity to purchase 5 unrestricted acres with exceptional Missouri River Valley views. Ideally located within walking distance of the charming town of Defiance and the Katy Trail. Enjoy a 10-minute scenic drive to several county parks, the Weldon Spring Conservation Area, Missouri River access, and the Busch Shooting Range. Or unwind at one of the region’s many wineries, as this

Sherry Ruyle Meyer & Company Real Estate

3077 S Missouri 94, Defiance, MO 63341
/18
$650,000
- 3 Beds
- 2 Baths
- 2,013 Sq Ft
215 Rugged Acres Ln, Defiance, MO 63341

Custom built, beautifully crafted home with over 2,000 sq feet of living space with luxury finishes. Located on 5 unrestricted acres, mostly wooded, outside New Melle in the heart of wine country. Private and peacefully located with access to major roads, living in country with easy access to all modern conveniences. Stepping Inside you are greeted with soaring 10' ceilings, open floor plan from

Dolly Sjoholm Call Dolly, LLC

215 Rugged Acres Ln, Defiance, MO 63341
/5
$279,900
- Land
- 5 Acres
- $55,980 per Acre
5001 Lily Ridge Ct, Defiance, MO 63341

Four Luxurious home sites, on 5 acre lots. Sunset Estates in St. Charles County MO. Located in the heart of Defiance and wine country. Bring your own builder/plans and build your dream home on one of these premium secluded, all wooded lots. Homesites are located on a private street with cul-de-sac. Homeowners will enjoy the peace and quiet, along with privacy. County water and high-speed

Bill McNair II First American Real Estate Co.

5001 Lily Ridge Ct, Defiance, MO 63341
/4
$154,000
- Land
- 5.13 Acres
- $30,019 per Acre
150 Steeple Point Dr Lot #10 Dr, Defiance, MO 63341

Gorgeous Lot in Steeple Point. Great views and quite living.

Dan Lauderdale Lauderdale Realty

150 Steeple Point Dr Lot #10 Dr, Defiance, MO 63341
/4
$350,000
- Land
- 5 Acres
- $70,000 per Acre
12 Still Waters Ct, Defiance, MO 63341

Nestled in the heart of St. Charles County near Defiance and New Melle, MO, Callaway Lake Estates offers a rare opportunity to build your dream home surrounded by natural beauty while remaining close to modern conveniences. This private community is designed for those seeking space, recreation, and long-term value. The development features 108 homesites, with 35 already sold in the first 18

Toni Dillon Trophy Properties & Auction

12 Still Waters Ct, Defiance, MO 63341
/67
$2,750,000
- 3 Beds
- 4.5 Baths
- 4,037 Sq Ft
353 Callaway Ridge Dr, Defiance, MO 63341

Experience the ultimate in privacy and natural beauty with this stunning custom waterfront property nestled on 37+ mostly wooded acres fronting the serene waters of Callaway Valley Lake. Crafted with exceptional attention to detail, this one-of-a-kind property showcases rich woodwork and impeccable craftsmanship throughout. Highlighted by a grand wood-paneled ceiling with softly arched beams, and

Kelly Beanblossom-Schlake Blondin Group, Inc

353 Callaway Ridge Dr, Defiance, MO 63341
/57
$950,000
- 4 Beds
- 4.5 Baths
- 4,579 Sq Ft
50 Sunfish Dr, Defiance, MO 63341

Experience the best of Callaway Valley living—where privacy, luxury, and lifestyle align.Situated on a stunning 6-acre estate with coveted lake rights, this exceptional property offers a rare blend of space, serenity, and high-end living.The heart of the home is a chef’s dream kitchen, beautifully updated in 2022 with a 48” Wolf gas range with pot filler, Sub-Zero refrigerator, expansive

Jessica Settlemoir Realty Shop

50 Sunfish Dr, Defiance, MO 63341
/4
$350,000
- Land
- 5 Acres
- $70,000 per Acre
510 Callaway Estates Dr, Defiance, MO 63341

Nestled in the heart of St. Charles County near Defiance and New Melle, MO, Callaway Lake Estates offers a rare opportunity to build your dream home surrounded by natural beauty while remaining close to modern conveniences. This private community is designed for those seeking space, recreation, and long-term value. The development features 108 homesites, with 35 already sold in the first 18

Toni Dillon Trophy Properties & Auction

510 Callaway Estates Dr, Defiance, MO 63341
/91
$785,000
- 4 Beds
- 3.5 Baths
- 4,564 Sq Ft
2 Woodridge Dr, Defiance, MO 63341

Spacious ranch home on 3 acres in one of the most beautiful settings in St. Charles County. Welcome home to picturesque rustic hardwood floors, a spacious country kitchen, large windows, vaulted ceilings, and TWO cozy fireplaces. The front, back, and side yards boast lovely mature trees placed perfectly to enhance the view and privacy. The pool (complete with a waterfall, salt water, and heater)

Kathleen Helbig EXP Realty, LLC

2 Woodridge Dr, Defiance, MO 63341
/2
$290,000
- Land
- 10.72 Acres
- $27,052 per Acre
190 Steeple Point Dr Lot #6 Dr, Defiance, MO 63341

Great home site in a rural setting.

Dan Lauderdale Lauderdale Realty

190 Steeple Point Dr Lot #6 Dr, Defiance, MO 63341
/12
$155,000
- Land
- 5.17 Acres
- $29,981 per Acre
160 Steeple Point Dr Lot #9 Dr, Defiance, MO 63341

Dan Lauderdale Lauderdale Realty

160 Steeple Point Dr Lot #9 Dr, Defiance, MO 63341

Missouri St. Charles County Defiance

Why Live in Defiance

Defiance, Missouri, is an unincorporated community in southwest St. Charles County, known for its expansive lots and rural charm. With a population of around 3,200, Defiance offers a blend of farms, vineyards and pastoral estates. Homes typically sit on lots of 5 acres or more, though 3-acre lots are also common. The Francis Howell School District serves the area, with students attending the highly rated Daniel Boone Elementary School, Francis Howell Middle School, and the newly relocated Francis Howell High School. Local attractions include the Defiance General Store on Highway 94, where residents can enjoy coffee, deli sandwiches and ice cream. For groceries, locals head to Schnucks in Weldon Spring. Defiance Ridge Vineyards offers hilltop views and locally made wines, and the area is dotted with other vineyards along Highway 94. Matson Hill State Park has 475 acres of forestland and 6 miles of trails, including gravity-flow paths for mountain biking. The park also houses the historic Hays Home, dating back to the 1830s. Despite residential growth, Defiance maintains its rural feel, providing a unique lifestyle within St. Charles County.

Learn more about living in Defiance

Frequently Asked Questions

What is the average home price in Defiance, MO?

Homes for sale in Defiance, MO have an average home price of $873,579.

Are home prices dropping in Defiance?

Yes, home prices in Defiance are down 2% in the last 12 months.

How many homes have sold over the last 12 months in Defiance, MO?

44 homes have sold in Defiance, MO over the last 12 months.

What are the most popular zip codes in Defiance, MO?

The most popular zip codes in Defiance, MO include 63341, 63073, 63005, 63348 and 63332.

How much do you need to make to afford a house in Defiance?

The median home price in Defiance is $750,000. If you put a 20% down payment of $150,000 and had a 30-year fixed mortgage with an interest rate of 6.3%, your estimated principal and interest payment would be $3,710 a month plus property taxes, HOA fees, home insurance, PMI, and utilities. Using the 28% rule, you would need to make at least $159K a year to afford the median home price in Defiance. Learn how much home you can afford with our Home Affordability Calculator.

How are the schools in Defiance, MO?

Defiance, MO has highly rated public and private schools. Some of the best schools in Defiance based on Niche Grades are Francis Howell High School, Daniel Boone Elementary School and Francis Howell Middle School. Browse all the schools in Defiance, MO to learn more.

Home Trends in Defiance, MO

On average, homes in Defiance, MO sell after 56 days on the market compared to the national average of 56 days. The median sale price for homes in Defiance, MO over the last 12 months is $615,000, down 2% from the median home sale price over the previous 12 months.

Housing Trends

Median Sale Price

$615,000

Median Single Family Sale Price

$685,000

Average Price Per Sq Ft

$220

Number of Homes for Sale

Last 12 months Home Sales

Months of Supply

2.70

Median List Price

$750,000

Median Change From 1st List Price

Median Home Sale Price YoY Change

-2%

How to Buy a Home How to Finance a Home How to Sell a Home

Defiance Types of Homes for Sale

More About Living in Defiance

Defiance Homes for Sale by Style

Defiance Ranch Style Homes for Sale

Homes for Sale in Nearby Cities

Homes for Sale in Nearby Counties

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