$999,999
- 4 Beds
- 5 Baths
- 2,436 Sq Ft
4075 Highway D, Defiance, MO 63341
John Shaw Tom Shaw, REALTORS
$999,999
4075 Highway D, Defiance, MO 63341
John Shaw Tom Shaw, REALTORS
$689,900
1330 Lake Hollow Dr, Defiance, MO 63341
Suzanne Matyiko ReeceNichols Real Estate
$575,000
640 Callaway Ridge Dr, Defiance, MO 63341
Julie Burt Blondin Group, Inc
$385,000
2934 S Highway 94, Defiance, MO 63341
Chris Neskar Compass Realty Group
$1,389,000 New Construction
170 Blue Sky, Defiance, MO 63341
Chris Dawson Orenda Real Estate Services
$799,000
2 Woodridge Dr, Defiance, MO 63341
Kathleen Helbig EXP Realty, LLC
$2,775,000
353 Callaway Ridge Dr, Defiance, MO 63341
Maureen Blondin Blondin Group, Inc
$830,000
3780 Forest Meadow Dr, Defiance, MO 63341
Emily Brophy MO Realty
Defiance, Missouri, is an unincorporated community in southwest St. Charles County, known for its expansive lots and rural charm. With a population of around 3,200, Defiance offers a blend of farms, vineyards and pastoral estates. Homes typically sit on lots of 5 acres or more, though 3-acre lots are also common. The Francis Howell School District serves the area, with students attending the highly rated Daniel Boone Elementary School, Francis Howell Middle School, and the newly relocated Francis Howell High School. Local attractions include the Defiance General Store on Highway 94, where residents can enjoy coffee, deli sandwiches and ice cream. For groceries, locals head to Schnucks in Weldon Spring. Defiance Ridge Vineyards offers hilltop views and locally made wines, and the area is dotted with other vineyards along Highway 94. Matson Hill State Park has 475 acres of forestland and 6 miles of trails, including gravity-flow paths for mountain biking. The park also houses the historic Hays Home, dating back to the 1830s. Despite residential growth, Defiance maintains its rural feel, providing a unique lifestyle within St. Charles County.
On average, homes in Defiance, MO sell after 74 days on the market compared to the national average of 54 days. The median sale price for homes in Defiance, MO over the last 12 months is $580,000, down 8% from the median home sale price over the previous 12 months.
In Defiance, there are currently 8 houses for sale, offering an array of options for potential buyers. With houses priced between $385,000 to $2,775,000, there's a range to accomodate every budget. As of February, 2026 the median home price in Defiance is $659,900, while the average sale price is $702,222, offering insights into the local housing market. On average, houses spend 74 days listed before being sold. Whether you're searching for a single-family residence, exploring single-family detached houses for sale, or considering new construction houses for sale, there are options to cater to different lifestyles. Explore the listings and houses for sale in Defiance, MO and find the perfect place to call home.