8

Defiance, MO Houses for Sale

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  • /30

    $999,999

    • 4 Beds
    • 5 Baths
    • 2,436 Sq Ft

    4075 Highway D, Defiance, MO 63341

    NOT IN A SUBDIVISION, NO INDENTURES OR RESTRICTIONS!!!! NEW ROOF.This is a must see!!! This beautifully updated, well maintained home with 3 beds, (3) full (2) 1/2 baths is on 10 flat acres. Primary bedroom has a bay window, separate shower/jacuzzi tub. Family room has a wood burning fireplace. Relax on the covered porch that overlooks a water feature and the lake. Kitchen has granite

    John Shaw Tom Shaw, REALTORS

    4075 Highway D, Defiance, MO 63341
  • /47

    $689,900

    • 4 Beds
    • 2.5 Baths
    • 2,556 Sq Ft

    1330 Lake Hollow Dr, Defiance, MO 63341

    Enjoy the serenity of your own private retreat, surrounded by trees and nature while still being just minutes from shopping, dining, and entertainment. Inside, the stunning kitchen is a true showpiece—featuring quartz countertops, cherry cabinetry, stainless steel appliances, a massive island, and a spacious walk-in pantry. The main level shines with new 5” wide wood-plank luxury vinyl flooring,

    Suzanne Matyiko ReeceNichols Real Estate

    1330 Lake Hollow Dr, Defiance, MO 63341
  • /45

    $575,000

    • 4 Beds
    • 3.5 Baths
    • 1,922 Sq Ft

    640 Callaway Ridge Dr, Defiance, MO 63341

    Discover the perfect blend of privacy, recreation and thoughtful updates in this 2-story home set on 3.24 picturesque acres in desirable Callaway Valley.Offering 4 bedrooms and 3.5 baths with 1,922 sf of finished living space above grade, this home delivers both functionality and flexibility. Numerous updates have been completed throughout, including refreshed bathrooms and improvements

    Julie Burt Blondin Group, Inc

    640 Callaway Ridge Dr, Defiance, MO 63341
  • /51

    $385,000

    • 3 Beds
    • 2 Baths
    • 1,225 Sq Ft

    2934 S Highway 94, Defiance, MO 63341

    Refurbished 100-year-old historic home in the heart of Defiance wine country, offering rare character and flexible potential. This property is ideal for buyers seeking lifestyle, income opportunity, or a creative use rather than a traditional suburban layout. Completely updated while preserving original charm. Currently zoned residential and well-suited for short-term rental use (buyer to

    Chris Neskar Compass Realty Group

    2934 S Highway 94, Defiance, MO 63341
  • /98

    $1,389,000 New Construction

    • 5 Beds
    • 5.5 Baths
    • 5,504 Sq Ft

    170 Blue Sky, Defiance, MO 63341

    Brand new custom-built home on 3+ wooded acres in Kohler Estates subdivision. Features 4 bedrooms and 5 1/2 baths, a oversized 4 car garage with stair access to basement, a Great Room with a stone gas fireplace, with custom bookshelves, Gourmet kitchen offers custom cabinetry with quartz countertops, tile backsplash, and a complete appliance package, and walk-in pantry with custom shelving.

    Chris Dawson Orenda Real Estate Services

    170 Blue Sky, Defiance, MO 63341
  • /91

    $799,000

    • 5 Beds
    • 3.5 Baths
    • 4,564 Sq Ft

    2 Woodridge Dr, Defiance, MO 63341

    Spacious ranch home on 3 acres in one of the most beautiful settings in St. Charles County. Welcome home to picturesque rustic hardwood floors, a spacious country kitchen, large windows, vaulted ceilings, and TWO cozy fireplaces. The front, back, and side yards boast lovely mature trees placed perfectly to enhance the view and privacy. The pool (complete with a waterfall, salt water, and heater)

    Kathleen Helbig EXP Realty, LLC

    2 Woodridge Dr, Defiance, MO 63341
  • /70

    $2,775,000

    • 3 Beds
    • 4.5 Baths
    • 4,037 Sq Ft

    353 Callaway Ridge Dr, Defiance, MO 63341

    Experience the ultimate in privacy and natural beauty with this stunning custom waterfront property nestled on 37+ mostly wooded acres fronting the serene waters of Callaway Valley Lake. Crafted with exceptional attention to detail, this one-of-a-kind property showcases rich woodwork and impeccable craftsmanship throughout. Highlighted by a grand wood-paneled ceiling with softly arched beams, and

    Maureen Blondin Blondin Group, Inc

    353 Callaway Ridge Dr, Defiance, MO 63341
  • /92

    $830,000

    • 5 Beds
    • 3.5 Baths
    • 4,814 Sq Ft

    3780 Forest Meadow Dr, Defiance, MO 63341

    Experience refined country living in this stunning 1.5-story estate nestled on a peaceful 3.43-acre lot. This 5-bedroom, 3.5-bath home combines timeless design, modern updates, and luxurious comfort throughout. The gourmet kitchen impresses with white cabinetry, gleaming quartz countertops, a large center island, and an inviting eat-in peninsula. A spacious walk-in pantry and a convenient wet bar

    Emily Brophy MO Realty

    3780 Forest Meadow Dr, Defiance, MO 63341

Why Live in Defiance

Defiance, Missouri, is an unincorporated community in southwest St. Charles County, known for its expansive lots and rural charm. With a population of around 3,200, Defiance offers a blend of farms, vineyards and pastoral estates. Homes typically sit on lots of 5 acres or more, though 3-acre lots are also common. The Francis Howell School District serves the area, with students attending the highly rated Daniel Boone Elementary School, Francis Howell Middle School, and the newly relocated Francis Howell High School. Local attractions include the Defiance General Store on Highway 94, where residents can enjoy coffee, deli sandwiches and ice cream. For groceries, locals head to Schnucks in Weldon Spring. Defiance Ridge Vineyards offers hilltop views and locally made wines, and the area is dotted with other vineyards along Highway 94. Matson Hill State Park has 475 acres of forestland and 6 miles of trails, including gravity-flow paths for mountain biking. The park also houses the historic Hays Home, dating back to the 1830s. Despite residential growth, Defiance maintains its rural feel, providing a unique lifestyle within St. Charles County.

Home Trends in Defiance, MO

Housing Trends

Median Sale Price
$580,000
Median Single Family Sale Price
$595,000
Average Price Per Sq Ft
$221
Number of Homes for Sale
8
Last 12 months Home Sales
45
Months of Supply
2.10
Median List Price
$659,900
Median Change From 1st List Price
4%
Median Home Sale Price YoY Change
-8%
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