Sikeston, MO Homes for Sale

• 

  

  /2

  $74,900

  • 3 Beds
  • 1 Bath
  • 1,252 Sq Ft

  512 S New Madrid St, Sikeston, MO 63801

  Great opportunity for investors! This 3-bedroom property offers solid potential as a rental or flip, with a manageable layout and room to add value. Whether you're expanding your portfolio or getting started in real estate, this is a smart, affordable option. Don't miss out on this income-producing opportunity—schedule a showing today to see the possibilities!

  Christina Essner EXP Realty, LLC

  512 S New Madrid St, Sikeston, MO 63801
• 

  

  

  /3

  $42,500

  • Land
  • 0.46 Acre
  • $92,391 per Acre

  311 Citation Dr, Sikeston, MO 63801

  Come see Sikeston's newest subdivision! These are excellent sites for first-time home buyers, families, or those wanting to downsize. Turn south off Broadway onto South Illinois Avenue to two new cul-de-sacs, ensuring reduced traffic. This subdivision is inside Sikeston City limits, and has covenants and restrictions to help protect your investment. Super easy, fast access to Highway 60 and

  Tim Merideth Century 21 Premiere Realty

  311 Citation Dr, Sikeston, MO 63801
• 

  

  

  /31

  $280,000

  • 3 Beds
  • 2 Baths
  • 2,009 Sq Ft

  608 State Highway H, Sikeston, MO 63801

  Looking for space, style, and function all in one? This brick home delivers. With 3 bedrooms, 2 full baths, and an open floor plan featuring a split-bedroom layout, it's designed for easy, comfortable living. The finishes make it truly move-in ready, while the layout offers both flow and privacy. Outside you'll find just over an acre of fenced ground, a circle drive, and a 2 car attached garage.

  Amber Prasanphanich EDGE Realty ERA Powered

  608 State Highway H, Sikeston, MO 63801
• 

  

  

  /12

  $264,900

  • 3 Beds
  • 2 Baths
  • 1,965 Sq Ft

  402 Garner St, Sikeston, MO 63801

  FIRST TIME ON THE MARKET !CUSTOM BUILT, ONE OWNER HOME, OPEN FLOOR PLAN WITH CUSTOM CABINETS, FLOORING , HUGE WALK IN SHOWER, INCLOSED SUNROOM ,ALL SITTING ON A LARGE CORNER LOT IN THE WESTVIEW SUBDIVISION AND SIKESTON SCHOOL DISTRICT .

  Tony McDonald McDonald Realty

  402 Garner St, Sikeston, MO 63801
• 

  

  /2

  $125,000

  • 3 Beds
  • 2 Baths
  • 1,554 Sq Ft

  2036 State Highway Y, Sikeston, MO 63801

  Enjoy peaceful living with all the conveniences of town just a short drive away! This 3-bedroom, 2-bath home offers comfort, space, and plenty of charm. Inside, you’ll find an open layout with lots of updates throughout. The spacious laundry room provides extra storage and functionality — perfect for busy families. Outside, the property sits on a huge yard, giving you plenty of room to garden,

  Lawren McMullan EDGE Realty, ERA Powered

  2036 State Highway Y, Sikeston, MO 63801
• 

  /2

  $15,000

  • Land
  • 0.24 Acre
  • $62,500 per Acre

  804 Cotton Ridge Dr, Sikeston, MO 63801

  This vacant residential lot is ready for you to build on, and priced to help you get started quickly. Covenants and restrictions are in place to help protect your investment. Located inside Sikeston City Limits. Additional Rooms: In Platted Subdv.

  Tim Merideth Century 21 Premiere Realty

  804 Cotton Ridge Dr, Sikeston, MO 63801
• 

  

  /4

  $184,000

  0 County Hwy 544 Unit MAR25013765, Sikeston, MO

  Nice small farm Interstate 55 and Interstate 57 agricultural and commercial property. Farm has been graded and is irrigated by neighbors well. Has County Road blacktop frontage.

  Jeff Carter

  0 County Hwy 544 Unit MAR25013765, Sikeston, MO
• 

  /2

  $200,000

  • 3 Beds
  • 2 Baths
  • 1,384 Sq Ft

  847 Cambridge Dr, Sikeston, MO 63801

  Welcome to this charming three-bedroom, two-bath brick home that blends comfort and style .Kitchen design has plenty of cabinet space. Primary bedroom with en-suite. Classic brick exterior for a timeless curb appeal. Partially finished basement featuring a wet bar making it ideal for recreation room or family room. Extra outside storage. Large patio perfect for outdoor entertaining. Ample off

  Paula Diebold EDGE Realty ERA Powered

  847 Cambridge Dr, Sikeston, MO 63801
• 

  /2

  $44,900

  • 2 Beds
  • 1.5 Baths
  • 576 Sq Ft

  136 N 6th St, Sikeston, MO 63801

  Great opportunity for investors! This 2-bedroom property offers solid potential as a rental or flip, with a manageable layout and room to add value. Whether you're expanding your portfolio or getting started in real estate, this is a smart, affordable option.

  Christina Essner EXP Realty, LLC

  136 N 6th St, Sikeston, MO 63801
• 

  

  /57

  $237,000

  • 5 Beds
  • 3.5 Baths
  • 2,262 Sq Ft

  203 N Kingshighway St, Sikeston, MO 63801

  Downtown Sikeston, multi-level property. Upper 2 bed apartment with balcony currently rented, Main level 3 bed, 2 bath remodeled with a basement newly vacant and ready for new tenants AND owners. Entrance/exterior doors in basement, side and main floors so every level has a seperate private entrance. One car garage and concrete parking off street for tenants or guests. Large finished area in the

  Lisa Russell EXP Realty LLC

  203 N Kingshighway St, Sikeston, MO 63801
• 

  

  /34

  $210,000 Open Sat 12PM - 1:30PM

  • 3 Beds
  • 2 Baths
  • 1,750 Sq Ft

  918 Hawthorn Dr, Sikeston, MO 63801

  Back on the Market- No Fault to Sellers! Beautiful and charming move-in ready ranch home! This thoughtfully updated property features a great floor plan with an open kitchen flowing into the dining room, 3 bedrooms on the main level, and a very spacious master bathroom. Step inside to a brand-new kitchen (2025) with modern finishes and some new appliances. Major updates include new HVAC,

  Christina Essner EXP Realty, LLC

  918 Hawthorn Dr, Sikeston, MO 63801
• 

  

  /83

  $549,000

  • 3 Beds
  • 4 Baths
  • 5,647 Sq Ft

  511 W Lindenwood Ave, Sikeston, MO 63801

  Welcome to your dream home! With over 5,600 sq ft of living space, this beautifully maintained residence offers the perfect blend of comfort, space, & style - ideal for a growing family or anyone who loves to entertain. The main level features an open-concept kitchen & living area, complete with custom cabinetry designed to accommodate all your culinary gadgets. Just off the living room, you’ll

  Lauren DeWitt EDGE Realty, ERA Powered

  511 W Lindenwood Ave, Sikeston, MO 63801
• 

  

  /3

  $42,500

  • Land
  • 0.32 Acre
  • $132,812 per Acre

  414 Secretariat, Sikeston, MO 63801

  Welcome to Saddleridge South, 2nd Addition! Located inside the city limits of Sikeston, these lots have utilities already ran to them and are ready for construction to begin. You can be the general contractor, or we can introduce you to some of the area's finest builders to work with. Covenants and restrictions were crafted to help protect property value and are available upon request. These

  Tim Merideth Century 21 Premiere Realty

  414 Secretariat, Sikeston, MO 63801
• 

  

  /17

  $309,900

  • 3 Beds
  • 2 Baths
  • 1,800 Sq Ft

  1201 Yosemite, Sikeston, MO 63801

  Beautiful new 3-bedroom, 2-bath home featuring an open living area with tray ceilings and a bright, modern feel. The kitchen is complete with granite countertops and stylish finishes, perfect for everyday living or entertaining. Enjoy the convenience of an attached garage and extra parking for guests. The fenced backyard offers privacy and space for outdoor fun or pets. Move-in ready and full of

  Leslie Ackman Young Real Estate LLC

  1201 Yosemite, Sikeston, MO 63801
• 

  /2

  $106,000

  • Land
  • 0.81 Acre
  • $130,864 per Acre

  130 Cypress Branch Rd, Sikeston, MO 63801

  Greenfield North will be a gated, fenced cul-de-sac community located inside the city limits of Sikeston, just off Highway 61. You'll experience the convenience of town combined with the calm of a quiet neighborhood. Enjoy a private, secure location for your custom home. The covenants and restrictions were designed to help preserve property values and maintain a safe, high-quality, and

  Tim Merideth Century 21 Premiere Realty

  130 Cypress Branch Rd, Sikeston, MO 63801
• 

  

  /3

  $42,500

  • Land
  • 0.14 Acre
  • $303,571 per Acre

  406 Aster, Sikeston, MO 63801

  Welcome to Saddleridge South, 2nd Addition! Located inside the city limits of Sikeston, these lots have utilities already ran to them and are ready for construction to begin. You can be the general contractor, or we can introduce you to some of the area's finest builders to work with. Covenants and restrictions were crafted to help protect property value and are available upon request. These

  Tim Merideth Century 21 Premiere Realty

  406 Aster, Sikeston, MO 63801
• 

  /2

  $15,000

  • Land
  • 0.24 Acre
  • $62,500 per Acre

  806 Cotton Ridge Dr, Sikeston, MO 63801

  This vacant residential lot is ready for you to build on, and priced to help you get started quickly. Covenants and restrictions are in place to help protect your investment. Located inside Sikeston City Limits. Additional Rooms: In Platted Subdv.

  Tim Merideth Century 21 Premiere Realty

  806 Cotton Ridge Dr, Sikeston, MO 63801
• 

  

  /3

  $42,500

  • Land
  • 0.29 Acre
  • $146,552 per Acre

  415 Secretariat, Sikeston, MO 63801

  Welcome to Saddleridge South, 2nd Addition! Located inside the city limits of Sikeston, these lots have utilities already ran to them and are ready for construction to begin. You can be the general contractor, or we can introduce you to some of the area's finest builders to work with. Covenants and restrictions were crafted to help protect property value and are available upon request. These

  Tim Merideth Century 21 Premiere Realty

  415 Secretariat, Sikeston, MO 63801
• 

  

  /99

  $790,000

  • 5 Beds
  • 5 Baths
  • 6,095 Sq Ft

  312 Tanner St, Sikeston, MO 63801

  Step into timeless charm with The Stallcup House, a grand historic estate built in 1909, nestled on 1.24 beautifully landscaped acres in the heart of Sikeston. This remarkable property spans two adjoining lots, zoned both residential and commercial, offering endless opportunities for living, entertaining, or business ventures. The main residence boasts over 5,000 square feet of refined

  Lauren DeWitt EDGE Realty, ERA Powered

  312 Tanner St, Sikeston, MO 63801
• 

  

  /3

  $42,500

  • Land
  • 0.47 Acre
  • $90,426 per Acre

  309 Citation Dr, Sikeston, MO 63801

  Come see Sikeston's newest subdivision! These are excellent sites for first-time home buyers, families, or those wanting to downsize. Turn south off Broadway onto South Illinois Avenue to two new cul-de-sacs, ensuring reduced traffic. This subdivision is inside Sikeston City limits, and has covenants and restrictions to help protect your investment. Super easy, fast access to Highway 60 and

  Tim Merideth Century 21 Premiere Realty

  309 Citation Dr, Sikeston, MO 63801
• 

  

  /3

  $42,500

  • Land
  • 0.34 Acre
  • $125,000 per Acre

  406 Secretariat, Sikeston, MO 63801

  Welcome to Saddleridge South, 2nd Addition! Located inside the city limits of Sikeston, these lots have utilities already ran to them and are ready for construction to begin. You can be the general contractor, or we can introduce you to some of the area's finest builders to work with. Covenants and restrictions were crafted to help protect property value and are available upon request. These

  Tim Merideth Century 21 Premiere Realty

  406 Secretariat, Sikeston, MO 63801
• 

  

  /17

  $219,000

  • 3 Beds
  • 2.5 Baths
  • 2,472 Sq Ft

  217 Foust Dr, Sikeston, MO 63801

  Welcome to 217 Foust Drive, a solid brick home built in 1988 and nestled in a quiet, well-established neighborhood. This spacious two-story residence offers three bedrooms, two and a half baths, and 2,472 square feet of comfortable living space.Enjoy the warmth of the wood-burning fireplace in the family room, along with a formal dining area and a second living space—perfect for

  Christy Lawrence C. Lawrence Realty LLC

  217 Foust Dr, Sikeston, MO 63801
• 

  

  /15

  $169,000

  0 Mo-Aa Unit MAR25029644, Sikeston, MO 63801

  Located in the heart of Southeast Missouri, this 67-acre tract of land lies between I-55 and Highway AA in Sikeston. Enrolled in the Wetlands Reserve Program (WRP), this property offers prime recreational and conservation value, making it ideal for hunting and outdoor recreation. With easy access via nearby major highways and a secluded feel, the property combines convenience and privacy. As WRP

  Lauren DeWitt EDGE Realty, ERA Powered

  0 Mo-Aa Unit MAR25029644, Sikeston, MO 63801
• 

  

  /8

  $94,900

  • 2 Beds
  • 1 Bath
  • 957 Sq Ft

  839 E Kathleen St, Sikeston, MO 63801

  Welcome to 839 E. Kathleen St., a cozy 2 bedroom, 1 bathroom home with character throughout. You'll love the original hardwood flooring and unique arched openings that give this home timeless appeal. Located right in the heart of Sikeston, you'll enjoy being close to schools, shopping, and local dining. Perfect for first-time buyers or anyone looking to downsize, this centrally located home

  Lauren DeWitt EDGE Realty, ERA Powered

  839 E Kathleen St, Sikeston, MO 63801
• 

  /2

  $15,000

  • Land
  • 0.24 Acre
  • $62,500 per Acre

  808 Cotton Ridge Dr, Sikeston, MO 63801

  This vacant residential lot is ready for you to build on, and priced to help you get started quickly. Covenants and restrictions are in place to help protect your investment. Located inside Sikeston City Limits. Additional Rooms: In Platted Subdv.

  Tim Merideth Century 21 Premiere Realty

  808 Cotton Ridge Dr, Sikeston, MO 63801
• 

  

  /14

  $40,900

  • 4 Beds
  • 1.5 Baths
  • 1,452 Sq Ft

  712 E Gladys St, Sikeston, MO 63801

  This property is available under the Freddie Mac First Look Initiative until 01/19/2026

  Nathaniel Simpson Trammell and Son Realty

  712 E Gladys St, Sikeston, MO 63801
• 

  /2

  $69,900

  • 2 Beds
  • 1 Bath
  • 884 Sq Ft

  819 E Kathleen St, Sikeston, MO 63801

  Great opportunity for investors! This 2-bedroom property offers solid potential as a rental or flip, with a manageable layout and room to add value. Whether you're expanding your portfolio or getting started in real estate, this is a smart, affordable option. Don't miss out on this income-producing opportunity.

  Christina Essner EXP Realty, LLC

  819 E Kathleen St, Sikeston, MO 63801
• 

  

  /3

  $42,500

  • Land
  • 0.46 Acre
  • $92,391 per Acre

  410 Secretariat, Sikeston, MO 63801

  Welcome to Saddleridge South, 2nd Addition! Located inside the city limits of Sikeston, these lots have utilities already ran to them and are ready for construction to begin. You can be the general contractor, or we can introduce you to some of the area's finest builders to work with. Covenants and restrictions were crafted to help protect property value and are available upon request. These

  Tim Merideth Century 21 Premiere Realty

  410 Secretariat, Sikeston, MO 63801
• 

  /2

  $39,000

  • 3 Beds
  • 1 Bath
  • 1,032 Sq Ft

  511 Clayton Ave, Sikeston, MO 63801

  If you are looking for an investment property or a home that requires some TLC, this home is ready for your renovations. Priced to sell quickly, schedule your viewing today!

  Thomas Williams Century 21 Premiere Realty

  511 Clayton Ave, Sikeston, MO 63801
• 

  /2

  $15,000

  • Land
  • 0.21 Acre
  • $71,429 per Acre

  809 Cotton Ridge Dr, Sikeston, MO 63801

  This vacant residential lot is ready for you to build on, and priced to help you get started quickly. Covenants and restrictions are in place to help protect your investment. Located inside Sikeston City Limits. Additional Rooms: In Platted Subdv.

  Tim Merideth Century 21 Premiere Realty

  809 Cotton Ridge Dr, Sikeston, MO 63801
• 

  

  /54

  $474,900

  832 County Line Rd, Sikeston, MO 63801

  New Listing! Situated in New Madrid County, Missouri, just west of Sikeston and south of Morehouse, this 163.02-acre property offers outstanding deer and duck hunting opportunities. A small portion of the land, about an acre, lies outside the Wetland Reserve Program (WRP) and provides an ideal location to build a home or cabin with electricity readily available nearby. The property boasts a

  Devin Hoehn AgriBuck Properties

  832 County Line Rd, Sikeston, MO 63801
• 

  

  /16

  $129,900

  • 3 Beds
  • 1 Bath
  • 987 Sq Ft

  614 Vaughn Ave, Sikeston, MO 63801

  614 Vaughn Ave., Sikeston is a freshly remodeled 3 bedroom, 1 bathroom home that's ready for it's new owner. Everything feels new, from the carpet and paint to the updated kitchen with brand new cabinets and countertops. You'll also love the new light fixtures and ceiling fans, a new inside HVAC unit, and some new windows for added comfort. Relax in the fully-fenced backyard, perfect for

  Lauren DeWitt EDGE Realty, ERA Powered

  614 Vaughn Ave, Sikeston, MO 63801
• 

  

  /3

  $42,500

  • Land
  • 0.47 Acre
  • $90,426 per Acre

  412 Secretariat, Sikeston, MO 63801

  Welcome to Saddleridge South, 2nd Addition! Located inside the city limits of Sikeston, these lots have utilities already ran to them and are ready for construction to begin. You can be the general contractor, or we can introduce you to some of the area's finest builders to work with. Covenants and restrictions were crafted to help protect property value and are available upon request. These

  Tim Merideth Century 21 Premiere Realty

  412 Secretariat, Sikeston, MO 63801
• 

  

  /6

  $95,000

  • Land
  • 0.81 Acre
  • $117,284 per Acre

  150 Cypress Branch Rd, Sikeston, MO 63801

  Greenfield North will be a gated, fenced cul-de-sac community located inside the city limits of Sikeston, just off Highway 61. You'll experience the convenience of town combined with the calm of a quiet neighborhood. Enjoy a private, secure location for your custom home. The covenants and restrictions were designed to help preserve property values and maintain a safe, high-quality, and

  Tim Merideth Century 21 Premiere Realty

  150 Cypress Branch Rd, Sikeston, MO 63801
• 

  

  /39

  $309,000

  • 4 Beds
  • 2.5 Baths
  • 3,492 Sq Ft

  303 Kennedy Dr, Sikeston, MO 63801

  Reduced! Large and spaciously laid out home. Three living areas, a recreational room/gym area by the 3 car garage, storage rooms and closets throughout. Updated and remodeled with new light fixtures, flooring, fresh paint throughout, bathroom remodels and tile work. HVAC 2018, Roof 2020, many nice features in this home. Room for friends and family for entertaining. Outdoor space is also ideal for

  Lisa Russell EXP Realty LLC

  303 Kennedy Dr, Sikeston, MO 63801
• 

  /2

  $15,000

  • Land
  • 0.2 Acre
  • $75,000 per Acre

  803 Bollweevil Blvd, Sikeston, MO 63801

  This vacant residential lot is ready for you to build on, and priced to help you get started quickly. Covenants and restrictions are in place to help protect your investment. Located inside Sikeston City Limits. Additional Rooms: In Platted Subdv.

  Tim Merideth Century 21 Premiere Realty

  803 Bollweevil Blvd, Sikeston, MO 63801
• 

  /2

  $89,900

  • 1 Bed
  • 1 Bath
  • 1,206 Sq Ft

  414 Matthews Ave, Sikeston, MO 63801

  Fantastic opportunity to own a duplex featuring 1 bedroom and 1 bathroom in each unit—perfect as a starter investment property or for those looking to live in one side and rent out the other to offset expenses. Each unit offers a manageable, low-maintenance layout ideal for singles, couples, or short-term rentals. Whether you're expanding your portfolio or just starting out, this property

  Christina Essner EXP Realty, LLC

  414 Matthews Ave, Sikeston, MO 63801
• 

  

  /3

  $42,500

  • Land
  • 0.28 Acre
  • $151,786 per Acre

  417 Secretariat, Sikeston, MO 63801

  Welcome to Saddleridge South, 2nd Addition! Located inside the city limits of Sikeston, these lots have utilities already ran to them and are ready for construction to begin. You can be the general contractor, or we can introduce you to some of the area's finest builders to work with. Covenants and restrictions were crafted to help protect property value and are available upon request. These

  Tim Merideth Century 21 Premiere Realty

  417 Secretariat, Sikeston, MO 63801
• 

  

  /5

  $159,000

  • Land
  • 1.08 Acres
  • $147,222 per Acre

  1405 N Main St, Sikeston, MO 63801

  Located on Highway 61, on the northern edge of Sikeston City limits, this tract is situated on a high-traffic state route that connect Sikeston with the City of Sikeston Industrial Park and Sikeston campus of Southeast Missouri State University. It is adjacent to Greenbriar and Fairfield Subdivisions; two of the town's nice subdivisions. Zoning is C-1 Neighborhood Shopping District, which is for

  Tim Merideth Century 21 Premiere Realty

  1405 N Main St, Sikeston, MO 63801
• 

  /2

  $38,000

  • 3 Beds
  • 1 Bath
  • 1,044 Sq Ft

  520 Coleman St, Sikeston, MO 63801

  If you are looking for an investment property or a home that requires some TLC, this home is ready for your renovations. Priced to sell quickly, schedule your viewing today!

  Thomas Williams Century 21 Premiere Realty

  520 Coleman St, Sikeston, MO 63801

Showing Results 81 - 120, Page 3 of 4